Luminal Mg2+, a key factor controlling RYR2-mediated Ca 2+ release: Cytoplasmic and luminal regulation modeled in a tetrameric channel

Journal of General Physiology

Volumn 132, Issue 4, 2008, Pages 429-446

  Laver, Derek R ^a   Honen, Bonny N ^a  

^a UNIVERSITY OF NEWCASTLE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CALCIUM CHANNEL; MAGNESIUM; RYANODINE RECEPTOR 2; TETRAMER; CALCIUM CHANNEL BLOCKING AGENT; RYANODINE RECEPTOR;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CALCIUM TRANSPORT; CELL ACTIVATION; CHANNEL GATING; CYTOPLASM; DIASTOLE; HEART MUSCLE; INHIBITION KINETICS; LIPID BILAYER; MOLECULAR MODEL; NONHUMAN; PHYSIOLOGY; POROSITY; PROTEIN STRUCTURE; RECEPTOR AFFINITY; RECEPTOR UPREGULATION; REGULATORY MECHANISM; UPREGULATION; ANIMAL; BIOLOGICAL MODEL; CALCIUM SIGNALING; CELL MEMBRANE POTENTIAL; CHEMISTRY; DRUG EFFECT; FINANCIAL MANAGEMENT; KINETICS; METABOLISM; MUSCLE CONTRACTION; PROTEIN DOMAIN; PROTEIN QUATERNARY STRUCTURE; SARCOPLASMIC RETICULUM; SHEEP; STRUCTURE ACTIVITY RELATION;

ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM SIGNALING; COMPETITIVE BIDDING; CYTOPLASM; ION CHANNEL GATING; KINETICS; LIPID BILAYERS; MAGNESIUM; MEMBRANE POTENTIALS; MODELS, BIOLOGICAL; MUSCLE CONTRACTION; MYOCARDIUM; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, QUATERNARY; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM; SHEEP; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 53549123851     PISSN: 00221295     EISSN: 00221295     Source Type: Journal    
DOI: 10.1085/jgp.200810001     Document Type: Article

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