Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia

Nature Medicine

Volumn 20, Issue 6, 2014, Pages 624-632

  Hong, Tingting ^a   Yang, Huanghe ^b,c   Zhang, Shan Shan ^a   Cho, Hee Cheol ^a   Kalashnikova, Mariya ^a   Sun, Baiming ^a   Zhang, Hao ^b   Bhargava, Anamika ^d   Grabe, Michael ^b   Olgin, Jeffrey ^c   Gorelik, Julia ^d   Marbán, Eduardo ^a   Jan, Lily Y ^b,c,e   Shaw, Robin M ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CALCIUM; CALCIUM CHANNEL; ISOPROTEIN; MEMBRANE PROTEIN; NEURAL WISKOTT ALDRICH SYNDROME PROTEIN; POTASSIUM ION; PROTEIN BIN1; PROTEIN BIN1+13+17; UNCLASSIFIED DRUG;

ACTIN POLYMERIZATION; ACTION POTENTIAL; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARRHYTHMOGENESIS; ARTICLE; BIN1 GENE; CARDIOMYOPATHY; CELL STRUCTURE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DOWN REGULATION; EXTRACELLULAR CALCIUM; GENE; GENE DELETION; HEART MUSCLE CELL; HEART VENTRICLE ARRHYTHMIA; HUMAN; HUMAN CELL; ION TRANSPORT; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; TRANSVERSE TUBULAR SYSTEM;

MUS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANALYSIS OF VARIANCE; ANIMALS; ARRHYTHMIAS, CARDIAC; BASE SEQUENCE; CALCIUM; CLONING, MOLECULAR; DNA PRIMERS; DNA PROBES; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; MYOCYTES, CARDIAC; NERVE TISSUE PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; SARCOLEMMA; TUMOR SUPPRESSOR PROTEINS;

EID: 84902208952     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3543     Document Type: Article

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