Slow Ca2+ sparks de-synchronize Ca2+ release in failing cardiomyocytes: Evidence for altered configuration of Ca2+ release units?

Journal of Molecular and Cellular Cardiology

Volumn 58, Issue 1, 2013, Pages 41-52

  Louch, William E ^a,b   Hake, Johan ^c,d   Mørk, Halvor K ^a,b   Hougen, Karina ^a,b   Skrbic, Biljana ^a,b   Ursu, Daniel ^e   Tønnessen, Theis ^a,b   Sjaastad, Ivar ^a,b   Sejersted, Ole M ^a,b  

^a ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d SIMULA RESEARCH LABORATORY   (Norway)

^e UNIVERSITY OF ULM   (Germany)

Author keywords

Ca2+ sparks; Ca2+ transient; Cardiomyocytes; Heart failure

Indexed keywords

CALCIUM; RYANODINE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM SIGNALING; CALCIUM SPARK; CALCIUM TRANSPORT; CELL ISOLATION; CHRONIC DISEASE; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; CORONARY ARTERY LIGATION; DISEASE MODEL; FEMALE; FOURIER TRANSFORMATION; HEART INFARCTION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART MUSCLE POTENTIAL; HEART VENTRICLE SEPTUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RECEPTOR DOWN REGULATION; SHAM PROCEDURE; TRANSVERSE TUBULAR SYSTEM;

ACTION POTENTIALS; ANIMALS; CALCIUM; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; HEART FAILURE; HUMANS; MICE; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM;

MURINAE; MUS;

EID: 84876313002     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2013.01.014     Document Type: Article

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