Termination of cardiac Ca2+ sparks: An investigative mathematical model of calcium-induced calcium release

Biophysical Journal

Volumn 83, Issue 1, 2002, Pages 59-78

  Sobie, Eric A ^a   Duly, Keith W ^a   Cruz, Jader Dos Santos ^a   Lederer, W Jonathan ^a,c   Jafri, M Saleet ^b  

^a UNIVERSITY OF MARYLAND   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

^c UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; RAPAMYCIN; RYANODINE RECEPTOR; TACROLIMUS;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; EXCITATION CONTRACTION COUPLING; HEART; MATHEMATICAL MODEL; MONTE CARLO METHOD; MOUSE; NONHUMAN;

ANIMALIA;

EID: 0036283045     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(02)75149-7     Document Type: Article

References (73)

1. Divalent cation activation and inhibition of single calcium release channels from sheep cardiac sarcoplasmic reticulum
2. Fractional SR Ca release is regulated by trigger Ca and SR Ca content in cardiac myocytes
3. 2+ release channels
4. Characterization and mapping of the 12 kDa FK506-binding protein (FKBP12)-binding site on different isoforms of the ryanodine receptor and of the inositol 1,4,5-trisphosphate receptor
5. i during excitation-contraction coupling in cardiac myocytes
6. The control of calcium release in heart muscle
7. Numerical analysis of ryanodine receptor activation by L-type channel activity in the cardiac muscle diad
8. Mechanisms underlying calcium sparks in cardiac muscle
9. Propagation of excitation-contraction coupling into ventricular myocytes
10. 2+-sparks
11. i waves in cardiac myocytes
12. Calcium sparks: Elementary events underlying excitation-contraction coupling in heart muscle
13. 2+ activation and inactivation sites on the luminal side of the cardiac ryanodine receptor complex
14. Calcium signalling in cardiac muscle: Refractoriness revealed by coherent activation
15. + currents by the immunosuppressant FK-506 in rat ventricle
16. + currents responsible for repolarization in mouse ventricle and their modulation by FK-506 and rapamycin
17. + currents in rat ventricular myocytes
18. Heightened sensitivity of a lattice of membrane receptors
19. Conformational spread in a ring of proteins: A stochastic approach to allostery
20. Calcium-induced release of calcium from the sarcoplasmic reticulum
21. Ryanodine receptor adaptation
22. 2+ release units in skeletal and cardiac muscle
23. 2+ release units and couplons in skeletal and cardiac muscles
24. 2+ sensing sites
25. 2+ release in heart
26. Sparks and puffs in oligodendrocyte progenitors: Cross talk between ryanodine receptors and inositol trisphosphate receptors
27. Resting myoplasmic free calcium in frog skeletal muscle fibers estimated with fluo-3
28. 2+ gradients during activation of frog skeletal muscle fibres imaged with confocal and two-photon microscopy
29. Postulated role of calsequestrin in the regulation of calcium release from sarcoplasmic reticulum
30. 2+ sparks
31. 2+ dynamics: The roles of ryanodine receptor adaptation and sarcoplasmic reticulum load
32. 2+ "sparks" in skeletal muscle
33. 2+ oscillations
34. Spark-to-wave transition: Saltatory transmission of calcium waves in cardiac myocytes
35. 2+ sparks in frog skeletal muscle recorded at high time resolution
36. Sodium-calcium exchange in excitable cells: Fuzzy space
37. Regulation of calcium release by calcium inside the sarcoplasmic reticulum in ventricular myocytes
38. 2+-sensitive leak in rat ventricular myocytes
39. 2+ sparks in rat ventricular myocytes
40. Immunophilin modulation of calcium channel gating
41. Coupled gating between cardiac calcium release channels (ryanodine receptors)
42. 2+ release channels (ryanodine receptors)
43. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): Defective regulation in failing hearts
44. 2+ transients in rat cardiac myocytes
45. 2+ release channel of skeletal and cardiac sarcoplasmic reticulum
46. 2+ current through cardiac ryanodine receptor channels under quasi-physiological ionic conditions
47. 2+ in single ventricular myocytes
48. Estimate of net calcium fluxes and sarcoplasmic reticulum calcium content during systole in rat ventricular myocytes
49. Localized intracellular calcium signaling in muscle: Calcium sparks and calcium quarks
50. Voltage-independent calcium release in heart muscle
51. Factors shaping the confocal image of the calcium spark in cardiac muscle cells
52. 2+ leak from the sarcoplasmic reticulum and increases contractility
53. 2+ release in the functional unit of the cardiac diadic space
54. 2+-release channel: Activation by caffeine
55. Contributions of electron microscopy and single-particle techniques to the determination of the ryanodine receptor three-dimensional structure
56. 2+ spark frequency in ventricular myocytes
57. 2+ sparks) originate at transverse tubules in rat heart cells
58. 2+ release by a local inactivation of ryanodine receptors in cardiac myocytes
59. Cryoelectron microscopy and image analysis of the cardiac ryanodine receptor
60. Do inactivation mechanisms rather than adaptation hold the key to understanding ryanodine receptor channel gating?
61. A simple numerical model of calcium spark formation and detection in cardiac myocytes
62. Numerical simulation of local calcium movements during L-type calcium channel gating in the cardiac diad
63. Theory of excitation-contraction coupling in cardiac muscle
64. Local control models of cardiac excitation-contraction coupling. A possible role for allosteric interactions between ryanodine receptors
65. 2+ sparks in rat cardiomyocytes
66. 2+
67. 2+ and phosphorylation
68. An estimate of the calcium content of the sarcoplasmic reticulum in rat ventricular myocytes
69. Locations of calmodulin and FK506-binding protein on the three-dimensional architecture of the skeletal muscle ryanodine receptor
70. 2+ sparks, and local control of excitation-contraction coupling in normal heart muscle
71. 2+ release channel closure in rat heart
72. 2+ leak through ryanodine receptor in heart failure
73. A minimal gating model for the cardiac calcium release channel