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Volumn 43-44, Issue , 2015, Pages 25-37

Neuropsychiatric symptoms in Alzheimer's disease: What might be associated brain circuits?

Author keywords

Agitation; Alzheimer's disease; Amygdala; Anterior cingulate cortex; Apathy; Delusions; Depression; Functional imaging; Inferior temporal cortex; Insula; Neuroimaging; Neuropsychiatric symptoms; Orbitrofrontal cortex; Posterior cingulate cortex

Indexed keywords

AGITATION; ALZHEIMER DISEASE; AMYGDALOID NUCLEUS; ANTERIOR CINGULATE; APATHY; AVOIDANCE BEHAVIOR; BRAIN FUNCTION; CONNECTOME; DELUSION; DEPRESSION; DISEASE ASSOCIATION; FRONTAL CORTEX; HIPPOCAMPUS; HUMAN; INFERIOR TEMPORAL CORTEX; NEUROCHEMISTRY; NEUROIMAGING; ORBITAL CORTEX; PHENOTYPE; POSTERIOR CINGULATE; PSYCHOSIS; REVIEW; THREAT; AMYGDALA; BRAIN; CINGULATE GYRUS; COMPLICATION; DELUSIONS; PATHOPHYSIOLOGY;

EID: 84943450221     PISSN: 00982997     EISSN: 18729452     Source Type: Journal    
DOI: 10.1016/j.mam.2015.05.005     Document Type: Review
Times cited : (202)

References (97)
  • 1
    • 84910005783 scopus 로고    scopus 로고
    • 2014 Alzheimer's disease facts and figures
    • Alzheimer's Association 2014 Alzheimer's disease facts and figures Alzheimers Dement 10 2014 e47 e92 10.1016/j.jalz.2014.02.001
    • (2014) Alzheimers Dement , vol.10 , pp. e47-e92
    • Alzheimer's Association1
  • 3
    • 84927110432 scopus 로고    scopus 로고
    • Resting-state frontostriatal functional connectivity in Parkinson's disease-related apathy
    • H.C. Baggio, B. Segura, J.L. Garrido-Millan, M.-J. Marti, Y. Compta, F. Valldeoriola, and et al. Resting-state frontostriatal functional connectivity in Parkinson's disease-related apathy Mov. Disord 30 2015 671 679 10.1002/mds.26137
    • (2015) Mov. Disord , vol.30 , pp. 671-679
    • Baggio, H.C.1    Segura, B.2    Garrido-Millan, J.L.3    Marti, M.-J.4    Compta, Y.5    Valldeoriola, F.6
  • 4
    • 84896394685 scopus 로고    scopus 로고
    • Neuropsychiatric symptoms in Alzheimer's disease are related to functional connectivity alterations in the salience network
    • M.L.F. Balthazar, F.R.S. Pereira, T.M. Lopes, E.L. da Silva, A.C. Coan, B.M. Campos, and et al. Neuropsychiatric symptoms in Alzheimer's disease are related to functional connectivity alterations in the salience network Hum. Brain Mapp 35 2014 1237 1246 10.1002/hbm.22248
    • (2014) Hum. Brain Mapp , vol.35 , pp. 1237-1246
    • Balthazar, M.L.F.1    Pereira, F.R.S.2    Lopes, T.M.3    Da Silva, E.L.4    Coan, A.C.5    Campos, B.M.6
  • 5
    • 79960908306 scopus 로고    scopus 로고
    • Sertraline or mirtazapine for depression in dementia (HTA-SADD): A randomised, multicentre, double-blind, placebo-controlled trial
    • S. Banerjee, J. Hellier, M. Dewey, R. Romeo, C. Ballard, R. Baldwin, and et al. Sertraline or mirtazapine for depression in dementia (HTA-SADD): a randomised, multicentre, double-blind, placebo-controlled trial Lancet 378 2011 403 411 10.1016/S0140-6736(11)60830-1
    • (2011) Lancet , vol.378 , pp. 403-411
    • Banerjee, S.1    Hellier, J.2    Dewey, M.3    Romeo, R.4    Ballard, C.5    Baldwin, R.6
  • 8
    • 50849127099 scopus 로고    scopus 로고
    • Neuroanatomical correlates of neuropsychiatric symptoms in Alzheimer's disease
    • P.D. Bruen, W.J. McGeown, M.F. Shanks, and A. Venneri Neuroanatomical correlates of neuropsychiatric symptoms in Alzheimer's disease Brain 131 2008 2455 2463 10.1093/brain/awn151
    • (2008) Brain , vol.131 , pp. 2455-2463
    • Bruen, P.D.1    McGeown, W.J.2    Shanks, M.F.3    Venneri, A.4
  • 9
    • 84879972321 scopus 로고    scopus 로고
    • Behavioral and psychological subsyndromes in Alzheimer's disease using the Neuropsychiatric Inventory
    • M. Canevelli, N. Adali, T. Voisin, M.E. Soto, G. Bruno, M. Cesari, and et al. Behavioral and psychological subsyndromes in Alzheimer's disease using the Neuropsychiatric Inventory Int. J. Geriatr. Psychiatry 28 2013 795 803 10.1002/gps.3904
    • (2013) Int. J. Geriatr. Psychiatry , vol.28 , pp. 795-803
    • Canevelli, M.1    Adali, N.2    Voisin, T.3    Soto, M.E.4    Bruno, G.5    Cesari, M.6
  • 10
    • 0030436357 scopus 로고    scopus 로고
    • Conceptualization of agitation: Results based on the Cohen-Mansfield Agitation Inventory and the Agitation Behavior Mapping Instrument
    • discussion 351-4
    • J. Cohen-Mansfield Conceptualization of agitation: results based on the Cohen-Mansfield Agitation Inventory and the Agitation Behavior Mapping Instrument Int. Psychogeriatr 8 Suppl. 3 1996 309 315 discussion 351-4
    • (1996) Int. Psychogeriatr , vol.8 , pp. 309-315
    • Cohen-Mansfield, J.1
  • 11
    • 84927697456 scopus 로고    scopus 로고
    • Agitation in cognitive disorders: International Psychogeriatric Association provisional consensus clinical and research definition
    • J. Cummings, J. Mintzer, H. Brodaty, M. Sano, S. Banerjee, D.P. Devanand, and et al. Agitation in cognitive disorders: International Psychogeriatric Association provisional consensus clinical and research definition Int. Psychogeriatr 27 2015 7 17 10.1017/S1041610214001963
    • (2015) Int. Psychogeriatr , vol.27 , pp. 7-17
    • Cummings, J.1    Mintzer, J.2    Brodaty, H.3    Sano, M.4    Banerjee, S.5    Devanand, D.P.6
  • 13
    • 84877626914 scopus 로고    scopus 로고
    • Toward the future of psychiatric diagnosis: The seven pillars of RDoC
    • B.N. Cuthbert, and T.R. Insel Toward the future of psychiatric diagnosis: the seven pillars of RDoC BMC Med 11 2013 126 10.1186/1741-7015-11-126
    • (2013) BMC Med , vol.11 , pp. 126
    • Cuthbert, B.N.1    Insel, T.R.2
  • 14
    • 77957319896 scopus 로고    scopus 로고
    • The Neuropsychiatric Inventory-Clinician rating scale (NPI-C): Reliability and validity of a revised assessment of neuropsychiatric symptoms in dementia
    • K. de Medeiros, P. Robert, S. Gauthier, F. Stella, A. Politis, J. Leoutsakos, and et al. The Neuropsychiatric Inventory-Clinician rating scale (NPI-C): reliability and validity of a revised assessment of neuropsychiatric symptoms in dementia Int. Psychogeriatr 22 2010 984 994 10.1017/S1041610210000876
    • (2010) Int. Psychogeriatr , vol.22 , pp. 984-994
    • De Medeiros, K.1    Robert, P.2    Gauthier, S.3    Stella, F.4    Politis, A.5    Leoutsakos, J.6
  • 15
    • 4344667151 scopus 로고    scopus 로고
    • Why voxel-based morphometric analysis should be used with great caution when characterizing group differences
    • C. Davatzikos Why voxel-based morphometric analysis should be used with great caution when characterizing group differences Neuroimage 23 2004 17 20 10.1016/j.neuroimage.2004.05.010
    • (2004) Neuroimage , vol.23 , pp. 17-20
    • Davatzikos, C.1
  • 16
    • 37249066622 scopus 로고    scopus 로고
    • Striatal dopamine transporter levels correlate with apathy in neurodegenerative diseases A SPECT study with partial volume effect correction
    • R. David, M. Koulibaly, M. Benoit, R. Garcia, H. Caci, J. Darcourt, and et al. Striatal dopamine transporter levels correlate with apathy in neurodegenerative diseases A SPECT study with partial volume effect correction Clin. Neurol. Neurosurg 110 2008 19 24 10.1016/j.clineuro.2007.08.007
    • (2008) Clin. Neurol. Neurosurg , vol.110 , pp. 19-24
    • David, R.1    Koulibaly, M.2    Benoit, M.3    Garcia, R.4    Caci, H.5    Darcourt, J.6
  • 18
    • 84908394422 scopus 로고    scopus 로고
    • A systematic review of relations between resting-state functional-MRI and treatment response in major depressive disorder
    • G.S. Dichter, D. Gibbs, and M.J. Smoski A systematic review of relations between resting-state functional-MRI and treatment response in major depressive disorder J. Affect. Disord 172C 2014 8 17 10.1016/j.jad.2014.09.028
    • (2014) J. Affect. Disord , vol.172 C , pp. 8-17
    • Dichter, G.S.1    Gibbs, D.2    Smoski, M.J.3
  • 19
    • 84921510703 scopus 로고    scopus 로고
    • Regional cortical thinning predicts worsening apathy and hallucinations across the Alzheimer disease spectrum
    • N.J. Donovan, L.P. Wadsworth, N. Lorius, J.J. Locascio, D.M. Rentz, K.A. Johnson, and et al. Regional cortical thinning predicts worsening apathy and hallucinations across the Alzheimer disease spectrum Am. J. Geriatr. Psychiatry 22 2014 1168 1179 10.1016/j.jagp.2013.03.006
    • (2014) Am. J. Geriatr. Psychiatry , vol.22 , pp. 1168-1179
    • Donovan, N.J.1    Wadsworth, L.P.2    Lorius, N.3    Locascio, J.J.4    Rentz, D.M.5    Johnson, K.A.6
  • 20
    • 13544268496 scopus 로고    scopus 로고
    • Cholinergic-serotonergic imbalance contributes to cognitive and behavioral symptoms in Alzheimer's disease
    • M. Garcia-Alloza, F.J. Gil-Bea, M. Diez-Ariza, Chen C.-H., P.T. Francis, B. Lasheras, and et al. Cholinergic-serotonergic imbalance contributes to cognitive and behavioral symptoms in Alzheimer's disease Neuropsychologia 43 2005 442 449 10.1016/j.neuropsychologia.2004.06.007
    • (2005) Neuropsychologia , vol.43 , pp. 442-449
    • Garcia-Alloza, M.1    Gil-Bea, F.J.2    Diez-Ariza, M.3    Chen, C.-H.4    Francis, P.T.5    Lasheras, B.6
  • 21
    • 84883557180 scopus 로고    scopus 로고
    • Neuropsychiatric symptoms in Alzheimer's disease: Past progress and anticipation of the future
    • Y.E. Geda, L.S. Schneider, L.N. Gitlin, D.S. Miller, G.S. Smith, J. Bell, and et al. Neuropsychiatric symptoms in Alzheimer's disease: past progress and anticipation of the future Alzheimers Dement 9 2013 602 608 10.1016/j.jalz.2012.12.001
    • (2013) Alzheimers Dement , vol.9 , pp. 602-608
    • Geda, Y.E.1    Schneider, L.S.2    Gitlin, L.N.3    Miller, D.S.4    Smith, G.S.5    Bell, J.6
  • 22
    • 52049121840 scopus 로고    scopus 로고
    • Resting-state functional connectivity in neuropsychiatric disorders
    • M. Greicius Resting-state functional connectivity in neuropsychiatric disorders Curr. Opin. Neurol 21 2008 424 430 10.1097/WCO.0b013e328306f2c5
    • (2008) Curr. Opin. Neurol , vol.21 , pp. 424-430
    • Greicius, M.1
  • 23
    • 84879369197 scopus 로고    scopus 로고
    • Uncertainty and anticipation in anxiety: An integrated neurobiological and psychological perspective
    • D.W. Grupe, and J.B. Nitschke Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective Nat. Rev. Neurosci 14 2013 488 501 10.1038/nrn3524
    • (2013) Nat. Rev. Neurosci , vol.14 , pp. 488-501
    • Grupe, D.W.1    Nitschke, J.B.2
  • 24
    • 84866765222 scopus 로고    scopus 로고
    • Tau phosphorylation in human brain: Relationship to behavioral disturbance in dementia
    • S.S. Guadagna, M.M.M. Esiri, R.J.R. Williams, and P.T.P. Francis Tau phosphorylation in human brain: relationship to behavioral disturbance in dementia Neurobiol. Aging 33 2012 2798 2806 10.1016/j.neurobiolaging.2012.01.015
    • (2012) Neurobiol. Aging , vol.33 , pp. 2798-2806
    • Guadagna, S.S.1    Esiri, M.M.M.2    Williams, R.J.R.3    Francis, P.T.P.4
  • 25
    • 84926328243 scopus 로고    scopus 로고
    • Apathy is associated with lower inferior temporal cortical thickness in mild cognitive impairment and normal elderly individuals
    • B.J. Guercio, N.J. Donovan, A. Ward, A. Schultz, N. Lorius, R.E. Amariglio, and et al. Apathy is associated with lower inferior temporal cortical thickness in mild cognitive impairment and normal elderly individuals J. Neuropsychiatry Clin. Neurosci 27 2015 e22 e27 10.1176/appi.neuropsych.13060141
    • (2015) J. Neuropsychiatry Clin. Neurosci , vol.27 , pp. e22-e27
    • Guercio, B.J.1    Donovan, N.J.2    Ward, A.3    Schultz, A.4    Lorius, N.5    Amariglio, R.E.6
  • 26
    • 84871908328 scopus 로고    scopus 로고
    • Apathy and white matter integrity in Alzheimer's disease: A whole brain analysis with tract-based spatial statistics
    • C. Hahn, H.K. Lim, Won W.Y., K.J. Ahn, W.-S. Jung, and C.U. Lee Apathy and white matter integrity in Alzheimer's disease: a whole brain analysis with tract-based spatial statistics PLoS ONE 8 2013 e53493 10.1371/journal.pone.0053493
    • (2013) PLoS ONE , vol.8 , pp. e53493
    • Hahn, C.1    Lim, H.K.2    Won, W.Y.3    Ahn, K.J.4    Jung, W.-S.5    Lee, C.U.6
  • 27
    • 84878358579 scopus 로고    scopus 로고
    • Monoamine neurocircuitry in depression and strategies for new treatments
    • M. Hamon, and P. Blier Monoamine neurocircuitry in depression and strategies for new treatments Prog. Neuropsychopharmacol Biol. Psychiatry 45 2013 54 63 10.1016/j.pnpbp.2013.04.009
    • (2013) Prog. Neuropsychopharmacol Biol. Psychiatry , vol.45 , pp. 54-63
    • Hamon, M.1    Blier, P.2
  • 28
    • 0034084817 scopus 로고    scopus 로고
    • Left frontotemporal hypoperfusion is associated with aggression in patients with dementia
    • N.N. Hirono, M.S.M. Mega, I.D.I. Dinov, F.F. Mishkin, and J.L.J. Cummings Left frontotemporal hypoperfusion is associated with aggression in patients with dementia Arch. Neurol 57 2000 861 866 10.1001/archneur.57.6.861
    • (2000) Arch. Neurol , vol.57 , pp. 861-866
    • Hirono, N.N.1    Mega, M.S.M.2    Dinov, I.D.I.3    Mishkin, F.F.4    Cummings, J.L.J.5
  • 29
    • 13444282255 scopus 로고    scopus 로고
    • Regional cerebral metabolism in early Alzheimer's disease with clinically significant apathy or depression
    • V.A. Holthoff, B. Beuthien-Baumann, E. Kalbe, S. Lüdecke, O. Lenz, G. Zündorf, and et al. Regional cerebral metabolism in early Alzheimer's disease with clinically significant apathy or depression Biol. Psychiatry 57 2005 412 421 10.1016/j.biopsych.2004.11.035
    • (2005) Biol. Psychiatry , vol.57 , pp. 412-421
    • Holthoff, V.A.1    Beuthien-Baumann, B.2    Kalbe, E.3    Lüdecke, S.4    Lenz, O.5    Zündorf, G.6
  • 30
    • 0026532438 scopus 로고
    • The Present Behavioural Examination (PBE): The development of an interview to measure current behavioural abnormalities
    • T. Hope, and C.G. Fairburn The Present Behavioural Examination (PBE): the development of an interview to measure current behavioural abnormalities Psychol. Med 22 1992 223 230
    • (1992) Psychol. Med , vol.22 , pp. 223-230
    • Hope, T.1    Fairburn, C.G.2
  • 31
    • 84928986430 scopus 로고    scopus 로고
    • Anatomical correlates of the neuropsychiatric symptoms in Alzheimer's disease
    • Hu X., D. Meiberth, B. Newport, and F. Jessen Anatomical correlates of the neuropsychiatric symptoms in Alzheimer's disease Curr. Alzheimer Res 12 2015 266 277
    • (2015) Curr. Alzheimer Res , vol.12 , pp. 266-277
    • Hu, X.1    Meiberth, D.2    Newport, B.3    Jessen, F.4
  • 32
    • 77954230363 scopus 로고    scopus 로고
    • Research domain criteria (RDoC): Toward a new classification framework for research on mental disorders
    • T. Insel, B. Cuthbert, M. Garvey, R. Heinssen, D.S. Pine, K. Quinn, and et al. Research domain criteria (RDoC): toward a new classification framework for research on mental disorders Am. J. Psychiatry 167 2010 748 751 10.1176/appi.ajp.2010.09091379
    • (2010) Am. J. Psychiatry , vol.167 , pp. 748-751
    • Insel, T.1    Cuthbert, B.2    Garvey, M.3    Heinssen, R.4    Pine, D.S.5    Quinn, K.6
  • 33
    • 84872379077 scopus 로고    scopus 로고
    • Tracking pathophysiological processes in Alzheimer's disease: An updated hypothetical model of dynamic biomarkers
    • C.R. Jack, D.S. Knopman, W.J. Jagust, R.C. Petersen, M.W. Weiner, P.S. Aisen, and et al. Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers Lancet Neurol 12 2013 207 216 10.1016/S1474-4422(12)70291-0
    • (2013) Lancet Neurol , vol.12 , pp. 207-216
    • Jack, C.R.1    Knopman, D.S.2    Jagust, W.J.3    Petersen, R.C.4    Weiner, M.W.5    Aisen, P.S.6
  • 34
    • 0033987420 scopus 로고    scopus 로고
    • Psychosis of Alzheimer's disease and related dementias. Diagnostic criteria for a distinct syndrome
    • D.V. Jeste, and S.I. Finkel Psychosis of Alzheimer's disease and related dementias. Diagnostic criteria for a distinct syndrome Am. J. Geriatr. Psychiatry 8 2000 29 34
    • (2000) Am. J. Geriatr. Psychiatry , vol.8 , pp. 29-34
    • Jeste, D.V.1    Finkel, S.I.2
  • 36
    • 84865738280 scopus 로고    scopus 로고
    • Regional cerebral blood flow abnormalities associated with apathy and depression in Alzheimer disease
    • Kang J.Y., J.S. Lee, Kang H., H.-W. Lee, Y.K. Kim, H.J. Jeon, and et al. Regional cerebral blood flow abnormalities associated with apathy and depression in Alzheimer disease Alzheimer Dis. Assoc. Disord 26 2012 217 224 10.1097/WAD.0b013e318231e5fc
    • (2012) Alzheimer Dis. Assoc. Disord , vol.26 , pp. 217-224
    • Kang, J.Y.1    Lee, J.S.2    Kang, H.3    Lee, H.-W.4    Kim, Y.K.5    Jeon, H.J.6
  • 38
    • 79960246201 scopus 로고    scopus 로고
    • Microstructural alteration of the anterior cingulum is associated with apathy in Alzheimer disease
    • J.W. Kim, D.Y. Lee, I.H. Choo, E.H. Seo, S.G. Kim, S.Y. Park, and et al. Microstructural alteration of the anterior cingulum is associated with apathy in Alzheimer disease Am. J. Geriatr. Psychiatry 19 2011 644 653 10.1097/JGP.0b013e31820dcc73
    • (2011) Am. J. Geriatr. Psychiatry , vol.19 , pp. 644-653
    • Kim, J.W.1    Lee, D.Y.2    Choo, I.H.3    Seo, E.H.4    Kim, S.G.5    Park, S.Y.6
  • 39
    • 84904766367 scopus 로고    scopus 로고
    • Psychosis in Alzheimer's disease is associated with frontal metabolic impairment and accelerated decline in working memory: Findings from the Alzheimer's Disease Neuroimaging Initiative
    • J. Koppel, S. Sunday, T.E. Goldberg, P. Davies, E. Christen, B.S. Greenwald, and et al. Psychosis in Alzheimer's disease is associated with frontal metabolic impairment and accelerated decline in working memory: findings from the Alzheimer's Disease Neuroimaging Initiative Am. J. Geriatr. Psychiatry 22 2014 698 707 10.1016/j.jagp.2012.10.028
    • (2014) Am. J. Geriatr. Psychiatry , vol.22 , pp. 698-707
    • Koppel, J.1    Sunday, S.2    Goldberg, T.E.3    Davies, P.4    Christen, E.5    Greenwald, B.S.6
  • 42
    • 0037174346 scopus 로고    scopus 로고
    • Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: Results from the cardiovascular health study
    • C.G. Lyketsos, O. Lopez, B. Jones, A.L. Fitzpatrick, J. Breitner, and S. DeKosky Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: results from the cardiovascular health study JAMA 288 2002 1475 1483
    • (2002) JAMA , vol.288 , pp. 1475-1483
    • Lyketsos, C.G.1    Lopez, O.2    Jones, B.3    Fitzpatrick, A.L.4    Breitner, J.5    DeKosky, S.6
  • 43
    • 2442542158 scopus 로고    scopus 로고
    • Forgotten frontal lobe syndrome or "executive Dysfunction Syndrome"
    • C.G. Lyketsos, A. Rosenblatt, and P. Rabins Forgotten frontal lobe syndrome or "Executive Dysfunction Syndrome" Psychosomatics 45 2004 247 255 10.1176/appi.psy.45.3.247
    • (2004) Psychosomatics , vol.45 , pp. 247-255
    • Lyketsos, C.G.1    Rosenblatt, A.2    Rabins, P.3
  • 47
    • 77950331205 scopus 로고    scopus 로고
    • Insular hypoperfusion correlates with the severity of delusions in individuals with Alzheimer's disease
    • T. Matsuoka, J. Narumoto, K. Shibata, A. Okamura, K. Nakamura, C. Okuyama, and et al. Insular hypoperfusion correlates with the severity of delusions in individuals with Alzheimer's disease Dement. Geriatr. Cogn. Disord 29 2010 287 293 10.1159/000295115
    • (2010) Dement. Geriatr. Cogn. Disord , vol.29 , pp. 287-293
    • Matsuoka, T.1    Narumoto, J.2    Shibata, K.3    Okamura, A.4    Nakamura, K.5    Okuyama, C.6
  • 50
    • 20844452049 scopus 로고    scopus 로고
    • Metabolic patterns associated with the clinical response to galantamine therapy: A fludeoxyglucose f 18 positron emission tomographic study
    • M.S. Mega, I.D. Dinov, V. Porter, G. Chow, E. Reback, P. Davoodi, and et al. Metabolic patterns associated with the clinical response to galantamine therapy: a fludeoxyglucose f 18 positron emission tomographic study Arch. Neurol 62 2005 721 728 10.1001/archneur.62.5.721
    • (2005) Arch. Neurol , vol.62 , pp. 721-728
    • Mega, M.S.1    Dinov, I.D.2    Porter, V.3    Chow, G.4    Reback, E.5    Davoodi, P.6
  • 51
    • 80053131124 scopus 로고    scopus 로고
    • Large-scale brain networks and psychopathology: A unifying triple network model
    • V. Menon Large-scale brain networks and psychopathology: a unifying triple network model Trends Cogn. Sci 15 2011 483 506 10.1016/j.tics.2011.08.003
    • (2011) Trends Cogn. Sci , vol.15 , pp. 483-506
    • Menon, V.1
  • 52
    • 84886711440 scopus 로고    scopus 로고
    • Cholinergic circuitry of the human nucleus basalis and its fate in Alzheimer's disease
    • M.M. Mesulam Cholinergic circuitry of the human nucleus basalis and its fate in Alzheimer's disease J. Comp. Neurol 521 2013 4124 4144 10.1002/cne.23415
    • (2013) J. Comp. Neurol , vol.521 , pp. 4124-4144
    • Mesulam, M.M.1
  • 53
    • 0034727605 scopus 로고    scopus 로고
    • Cholinergic deficits contribute to behavioral disturbance in patients with dementia
    • S.L. Minger, M.M. Esiri, B. McDonald, J. Keene, J. Carter, T. Hope, and et al. Cholinergic deficits contribute to behavioral disturbance in patients with dementia Neurology 55 2000 1460 1467
    • (2000) Neurology , vol.55 , pp. 1460-1467
    • Minger, S.L.1    Esiri, M.M.2    McDonald, B.3    Keene, J.4    Carter, J.5    Hope, T.6
  • 54
    • 84901657110 scopus 로고    scopus 로고
    • Regional atrophy of the insular cortex is associated with neuropsychiatric symptoms in Alzheimer's disease patients
    • Y. Moon, W.-J. Moon, H. Kim, and Han S.-H. Regional atrophy of the insular cortex is associated with neuropsychiatric symptoms in Alzheimer's disease patients Eur. Neurol 71 2014 223 229 10.1159/000356343
    • (2014) Eur. Neurol , vol.71 , pp. 223-229
    • Moon, Y.1    Moon, W.-J.2    Kim, H.3    Han, S.-H.4
  • 56
    • 84871626293 scopus 로고    scopus 로고
    • Neuroanatomical abnormalities before onset of delusions in patients with Alzheimer's disease: A voxel-based morphometry study
    • S. Nakaaki, J. Sato, K. Torii, M. Oka, A. Negi, T. Nakamae, and et al. Neuroanatomical abnormalities before onset of delusions in patients with Alzheimer's disease: a voxel-based morphometry study Neuropsychiatr. Dis. Treat 9 2013 1 8 10.2147/NDT.S38939
    • (2013) Neuropsychiatr. Dis. Treat , vol.9 , pp. 1-8
    • Nakaaki, S.1    Sato, J.2    Torii, K.3    Oka, M.4    Negi, A.5    Nakamae, T.6
  • 57
    • 84901475472 scopus 로고    scopus 로고
    • Systematic review of neuroimaging correlates of executive functioning: Converging evidence from different clinical populations
    • M.A. Nowrangi, C. Lyketsos, Rao V., and C.A. Munro Systematic review of neuroimaging correlates of executive functioning: converging evidence from different clinical populations J. Neuropsychiatry Clin. Neurosci 26 2014 114 125 10.1176/appi.neuropsych.12070176
    • (2014) J. Neuropsychiatry Clin. Neurosci , vol.26 , pp. 114-125
    • Nowrangi, M.A.1    Lyketsos, C.2    Rao, V.3    Munro, C.A.4
  • 58
  • 59
    • 64049083876 scopus 로고    scopus 로고
    • Atlas-based whole brain white matter analysis using large deformation diffeomorphic metric mapping: Application to normal elderly and Alzheimer's disease participants
    • K. Oishi, A. Faria, Jiang H., Li X., K. Akhter, Zhang J., and et al. Atlas-based whole brain white matter analysis using large deformation diffeomorphic metric mapping: application to normal elderly and Alzheimer's disease participants Neuroimage 46 2009 486 499
    • (2009) Neuroimage , vol.46 , pp. 486-499
    • Oishi, K.1    Faria, A.2    Jiang, H.3    Li, X.4    Akhter, K.5    Zhang, J.6
  • 61
    • 84862223923 scopus 로고    scopus 로고
    • Relationship between apathy and diffusion tensor imaging metrics of the brain in Alzheimer's disease
    • M. Ota, N. Sato, Y. Nakata, K. Arima, and M. Uno Relationship between apathy and diffusion tensor imaging metrics of the brain in Alzheimer's disease Int. J. Geriatr. Psychiatry 27 2012 722 726 10.1002/gps.2779
    • (2012) Int. J. Geriatr. Psychiatry , vol.27 , pp. 722-726
    • Ota, M.1    Sato, N.2    Nakata, Y.3    Arima, K.4    Uno, M.5
  • 62
    • 84928957026 scopus 로고    scopus 로고
    • Neuropsychiatric symptoms as predictors of progression to severe Alzheimer's dementia and death: The cache county dementia progression study
    • appiajp201414040480
    • M.E. Peters, S. Schwartz, Han D., P.V. Rabins, M. Steinberg, J.T. Tschanz, and et al. Neuropsychiatric symptoms as predictors of progression to severe Alzheimer's dementia and death: the cache county dementia progression study Am. J. Psychiatry 172 2015 460 465 10.1176/appi.ajp.2014.14040480 appiajp201414040480
    • (2015) Am. J. Psychiatry , vol.172 , pp. 460-465
    • Peters, M.E.1    Schwartz, S.2    Han, D.3    Rabins, P.V.4    Steinberg, M.5    Tschanz, J.T.6
  • 63
    • 84894122063 scopus 로고    scopus 로고
    • Effect of citalopram on agitation in Alzheimer disease: The CitAD randomized clinical trial
    • A.P. Porsteinsson, L.T. Drye, B.G. Pollock, D.P. Devanand, C. Frangakis, Z. Ismail, and et al. Effect of citalopram on agitation in Alzheimer disease: the CitAD randomized clinical trial JAMA 311 2014 682 691 10.1001/jama.2014.93
    • (2014) JAMA , vol.311 , pp. 682-691
    • Porsteinsson, A.P.1    Drye, L.T.2    Pollock, B.G.3    Devanand, D.P.4    Frangakis, C.5    Ismail, Z.6
  • 64
    • 84876060144 scopus 로고    scopus 로고
    • Antidepressants normalize the default mode network in patients with dysthymia
    • J. Posner, D.J. Hellerstein, I. Gat, A. Mechling, K. Klahr, Wang Z., and et al. Antidepressants normalize the default mode network in patients with dysthymia JAMA Psychiatry 70 2013 373 382 10.1001/jamapsychiatry.2013.455
    • (2013) JAMA Psychiatry , vol.70 , pp. 373-382
    • Posner, J.1    Hellerstein, D.J.2    Gat, I.3    Mechling, A.4    Klahr, K.5    Wang, Z.6
  • 65
    • 72049127264 scopus 로고    scopus 로고
    • Neurocircuitry of Mood Disorders
    • J.L. Price, and W.C. Drevets Neurocircuitry of Mood Disorders Neuropsychopharmacology 35 2010 192 216 10.1038/npp.2009.104
    • (2010) Neuropsychopharmacology , vol.35 , pp. 192-216
    • Price, J.L.1    Drevets, W.C.2
  • 66
    • 84855312099 scopus 로고    scopus 로고
    • Neural circuits underlying the pathophysiology of mood disorders
    • J.L.J. Price, and W.C.W. Drevets Neural circuits underlying the pathophysiology of mood disorders Trends Cogn. Sci 16 2012 61 71 10.1016/j.tics.2011.12.011
    • (2012) Trends Cogn. Sci , vol.16 , pp. 61-71
    • Price, J.L.J.1    Drevets, W.C.W.2
  • 67
    • 79955444505 scopus 로고    scopus 로고
    • A phase II trial of huperzine A in mild to moderate Alzheimer disease
    • M.S. Rafii, S. Walsh, J.T. Little, K. Behan, B. Reynolds, C. Ward, and et al. A phase II trial of huperzine A in mild to moderate Alzheimer disease Neurology 76 2011 1389 1394 10.1212/WNL.0b013e318216eb7b
    • (2011) Neurology , vol.76 , pp. 1389-1394
    • Rafii, M.S.1    Walsh, S.2    Little, J.T.3    Behan, K.4    Reynolds, B.5    Ward, C.6
  • 68
    • 84898940271 scopus 로고    scopus 로고
    • Neuropsychiatric symptoms and regional neocortical atrophy in mild cognitive impairment and Alzheimer's disease
    • M.S. Rafii, C.S. Taylor, H.T. Kim, R.S. Desikan, A.S. Fleisher, D. Katibian, and et al. Neuropsychiatric symptoms and regional neocortical atrophy in mild cognitive impairment and Alzheimer's disease Am. J. Alzheimers Dis. Other Demen 29 2014 159 165 10.1177/1533317513507373
    • (2014) Am. J. Alzheimers Dis. Other Demen , vol.29 , pp. 159-165
    • Rafii, M.S.1    Taylor, C.S.2    Kim, H.T.3    Desikan, R.S.4    Fleisher, A.S.5    Katibian, D.6
  • 69
    • 62149141359 scopus 로고    scopus 로고
    • Increased striatal dopamine (D2/D3) receptor availability and delusions in Alzheimer disease
    • S. Reeves, R. Brown, R. Howard, and P. Grasby Increased striatal dopamine (D2/D3) receptor availability and delusions in Alzheimer disease Neurology 72 2009 528 534 10.1212/01.wnl.0000341932.21961.f3
    • (2009) Neurology , vol.72 , pp. 528-534
    • Reeves, S.1    Brown, R.2    Howard, R.3    Grasby, P.4
  • 70
    • 60849137194 scopus 로고    scopus 로고
    • Proposed diagnostic criteria for apathy in Alzheimer's disease and other neuropsychiatric disorders
    • P. Robert, C.U. Onyike, A.F.G. Leentjens, K. Dujardin, P. Aalten, S. Starkstein, and et al. Proposed diagnostic criteria for apathy in Alzheimer's disease and other neuropsychiatric disorders Eur. Psychiatry 24 2009 98 104 10.1016/j.eurpsy.2008.09.001
    • (2009) Eur. Psychiatry , vol.24 , pp. 98-104
    • Robert, P.1    Onyike, C.U.2    Leentjens, A.F.G.3    Dujardin, K.4    Aalten, P.5    Starkstein, S.6
  • 71
    • 0036904309 scopus 로고    scopus 로고
    • The apathy inventory: Assessment of apathy and awareness in Alzheimer"s disease, Parkinson"s disease and mild cognitive impairment
    • P.H. Robert, S. Clairet, M. Benoit, J. Koutaich, C. Bertogliati, O. Tible, and et al. The apathy inventory: assessment of apathy and awareness in Alzheimer"s disease, Parkinson"s disease and mild cognitive impairment Int. J. Geriatr. Psychiatry 17 2002 1099 1105 10.1002/gps.755
    • (2002) Int. J. Geriatr. Psychiatry , vol.17 , pp. 1099-1105
    • Robert, P.H.1    Clairet, S.2    Benoit, M.3    Koutaich, J.4    Bertogliati, C.5    Tible, O.6
  • 72
    • 33746494905 scopus 로고    scopus 로고
    • Lack of initiative and interest in Alzheimer's disease: A single photon emission computed tomography study
    • P.H. Robert, G. Darcourt, M.P. Koulibaly, S. Clairet, M. Benoit, R. Garcia, and et al. Lack of initiative and interest in Alzheimer's disease: a single photon emission computed tomography study Eur. J. Neurol 13 2006 729 735 10.1111/j.1468-1331.2006.01088.x
    • (2006) Eur. J. Neurol , vol.13 , pp. 729-735
    • Robert, P.H.1    Darcourt, G.2    Koulibaly, M.P.3    Clairet, S.4    Benoit, M.5    Garcia, R.6
  • 73
    • 84866565986 scopus 로고    scopus 로고
    • The serotonergic system in ageing and Alzheimer's disease
    • J.J. Rodríguez, H.N. Noristani, and A. Verkhratsky The serotonergic system in ageing and Alzheimer's disease Prog. Neurobiol 99 2012 15 41 10.1016/j.pneurobio.2012.06.010
    • (2012) Prog. Neurobiol , vol.99 , pp. 15-41
    • Rodríguez, J.J.1    Noristani, H.N.2    Verkhratsky, A.3
  • 75
    • 84883176211 scopus 로고    scopus 로고
    • Safety and efficacy of methylphenidate for apathy in Alzheimer's disease: A randomized, placebo-controlled trial
    • P.B. Rosenberg, K.L. Lanctôt, L.T. Drye, N. Herrmann, R.W. Scherer, D.L. Bachman, and et al. Safety and efficacy of methylphenidate for apathy in Alzheimer's disease: a randomized, placebo-controlled trial J. Clin. Psychiatry 74 2013 810 816 10.4088/JCP.12m08099
    • (2013) J. Clin. Psychiatry , vol.74 , pp. 810-816
    • Rosenberg, P.B.1    Lanctôt, K.L.2    Drye, L.T.3    Herrmann, N.4    Scherer, R.W.5    Bachman, D.L.6
  • 77
    • 33745188219 scopus 로고    scopus 로고
    • Tract-based spatial statistics: Voxelwise analysis of multi-subject diffusion data
    • S.M. Smith, M. Jenkinson, H. Johansen-Berg, D. Rueckert, T.E. Nichols, C.E. Mackay, and et al. Tract-based spatial statistics: voxelwise analysis of multi-subject diffusion data Neuroimage 31 2006 1487 1505 10.1016/j.neuroimage.2006.02.024
    • (2006) Neuroimage , vol.31 , pp. 1487-1505
    • Smith, S.M.1    Jenkinson, M.2    Johansen-Berg, H.3    Rueckert, D.4    Nichols, T.E.5    MacKay, C.E.6
  • 78
    • 33646897697 scopus 로고    scopus 로고
    • The Lille apathy rating scale (LARS), a new instrument for detecting and quantifying apathy: Validation in Parkinson's disease
    • P. Sockeel, K. Dujardin, D. Devos, C. Denève, A. Destée, and L. Defebvre The Lille apathy rating scale (LARS), a new instrument for detecting and quantifying apathy: validation in Parkinson's disease J. Neurol. Neurosurg. Psychiatry 77 2006 579 584 10.1136/jnnp.2005.075929
    • (2006) J. Neurol. Neurosurg. Psychiatry , vol.77 , pp. 579-584
    • Sockeel, P.1    Dujardin, K.2    Devos, D.3    Denève, C.4    Destée, A.5    Defebvre, L.6
  • 79
    • 42449100871 scopus 로고    scopus 로고
    • Behavioural and psychological symptoms are not related to white matter hyperintensities and medial temporal lobe atrophy in Alzheimer's disease
    • S.S. Staekenborg, F. Gillissen, R. Romkes, Y.A.L. Pijnenburg, F. Barkhof, P. Scheltens, and et al. Behavioural and psychological symptoms are not related to white matter hyperintensities and medial temporal lobe atrophy in Alzheimer's disease Int. J. Geriatr. Psychiatry 23 2008 387 392 10.1002/gps.1891
    • (2008) Int. J. Geriatr. Psychiatry , vol.23 , pp. 387-392
    • Staekenborg, S.S.1    Gillissen, F.2    Romkes, R.3    Pijnenburg, Y.A.L.4    Barkhof, F.5    Scheltens, P.6
  • 80
    • 84886085235 scopus 로고    scopus 로고
    • Behavioural and emotional symptoms of apathy are associated with distinct patterns of brain atrophy in neurodegenerative disorders
    • B.R. Stanton, P.N. Leigh, R.J. Howard, G.J. Barker, and R.G. Brown Behavioural and emotional symptoms of apathy are associated with distinct patterns of brain atrophy in neurodegenerative disorders J. Neurol 260 2013 2481 2490 10.1007/s00415-013-6989-9
    • (2013) J. Neurol , vol.260 , pp. 2481-2490
    • Stanton, B.R.1    Leigh, P.N.2    Howard, R.J.3    Barker, G.J.4    Brown, R.G.5
  • 84
    • 46749095495 scopus 로고    scopus 로고
    • Clinical symptom responses to atypical antipsychotic medications in Alzheimer's disease: Phase 1 outcomes from the CATIE-AD effectiveness trial
    • D.L. Sultzer, S.M. Davis, P.N. Tariot, K.S. Dagerman, B.D. Lebowitz, C.G. Lyketsos, and et al. Clinical symptom responses to atypical antipsychotic medications in Alzheimer's disease: phase 1 outcomes from the CATIE-AD effectiveness trial Am. J. Psychiatry 165 2008 844 854 10.1176/appi.ajp.2008.07111779
    • (2008) Am. J. Psychiatry , vol.165 , pp. 844-854
    • Sultzer, D.L.1    Davis, S.M.2    Tariot, P.N.3    Dagerman, K.S.4    Lebowitz, B.D.5    Lyketsos, C.G.6
  • 85
    • 84871349795 scopus 로고    scopus 로고
    • Diffusion tensor imaging of neuropsychiatric symptoms in mild cognitive impairment and Alzheimer's dementia
    • S.K. Tighe, K. Oishi, S. Mori, G.S. Smith, M. Albert, C.G. Lyketsos, and et al. Diffusion tensor imaging of neuropsychiatric symptoms in mild cognitive impairment and Alzheimer's dementia J. Neuropsychiatry Clin. Neurosci 24 2012 484 488 10.1176/appi.neuropsych.11120375
    • (2012) J. Neuropsychiatry Clin. Neurosci , vol.24 , pp. 484-488
    • Tighe, S.K.1    Oishi, K.2    Mori, S.3    Smith, G.S.4    Albert, M.5    Lyketsos, C.G.6
  • 86
    • 84866009029 scopus 로고    scopus 로고
    • Reduced structural connectivity of a major frontolimbic pathway in generalized anxiety disorder
    • D.P.M. Tromp, D.W. Grupe, D.J. Oathes, D.R. McFarlin, P.J. Hernandez, T.R.A. Kral, and et al. Reduced structural connectivity of a major frontolimbic pathway in generalized anxiety disorder Arch. Gen. Psychiatry 69 2012 925 934 10.1001/archgenpsychiatry.2011.2178
    • (2012) Arch. Gen. Psychiatry , vol.69 , pp. 925-934
    • Tromp, D.P.M.1    Grupe, D.W.2    Oathes, D.J.3    McFarlin, D.R.4    Hernandez, P.J.5    Kral, T.R.A.6
  • 87
    • 84880164791 scopus 로고    scopus 로고
    • Subscale validation of the neuropsychiatric inventory questionnaire: Comparison of Alzheimer's disease neuroimaging initiative and National Alzheimer's Coordinating Center Cohorts
    • P.T. Trzepacz, A. Saykin, Yu P., P. Bhamditipati, Sun J., E.B. Dennehy, and et al. Subscale validation of the neuropsychiatric inventory questionnaire: comparison of Alzheimer's disease neuroimaging initiative and National Alzheimer's Coordinating Center Cohorts Am. J. Geriatr. Psychiatry 21 2013 607 622 10.1016/j.jagp.2012.10.027
    • (2013) Am. J. Geriatr. Psychiatry , vol.21 , pp. 607-622
    • Trzepacz, P.T.1    Saykin, A.2    Yu, P.3    Bhamditipati, P.4    Sun, J.5    Dennehy, E.B.6
  • 88
    • 84885593174 scopus 로고    scopus 로고
    • Frontolimbic atrophy is associated with agitation and aggression in mild cognitive impairment and Alzheimer's disease
    • P.T. Trzepacz, Yu P., P.K. Bhamidipati, B. Willis, T. Forrester, L. Tabas, and et al. Frontolimbic atrophy is associated with agitation and aggression in mild cognitive impairment and Alzheimer's disease Alzheimers Dement 9 2013 S95 S104 10.1016/j.jalz.2012.10.005 e1
    • (2013) Alzheimers Dement , vol.9 , pp. S95-S104
    • Trzepacz, P.T.1    Yu, P.2    Bhamidipati, P.K.3    Willis, B.4    Forrester, T.5    Tabas, L.6
  • 90
    • 84875860951 scopus 로고    scopus 로고
    • Dysconnectivity, large-scale networks and neuronal dynamics in schizophrenia
    • P.J. Uhlhaas Dysconnectivity, large-scale networks and neuronal dynamics in schizophrenia Curr. Opin. Neurobiol 23 2013 283 290 10.1016/j.conb.2012.11.004
    • (2013) Curr. Opin. Neurobiol , vol.23 , pp. 283-290
    • Uhlhaas, P.J.1
  • 91
    • 84883554401 scopus 로고    scopus 로고
    • Behavioral correlates of cerebrospinal fluid amino acid and biogenic amine neurotransmitter alterations in dementia
    • Y. Vermeiren, N. Le Bastard, A. Van Hemelrijck, W.H. Drinkenburg, S. Engelborghs, and P.P. De Deyn Behavioral correlates of cerebrospinal fluid amino acid and biogenic amine neurotransmitter alterations in dementia Alzheimers Dement 9 2013 488 498 10.1016/j.jalz.2012.06.010
    • (2013) Alzheimers Dement , vol.9 , pp. 488-498
    • Vermeiren, Y.1    Le Bastard, N.2    Van Hemelrijck, A.3    Drinkenburg, W.H.4    Engelborghs, S.5    De Deyn, P.P.6
  • 92
    • 84912087058 scopus 로고    scopus 로고
    • Brain region-specific monoaminergic correlates of neuropsychiatric symptoms in Alzheimer's disease
    • Y. Vermeiren, D. Van Dam, T. Aerts, S. Engelborghs, and P.P. De Deyn Brain region-specific monoaminergic correlates of neuropsychiatric symptoms in Alzheimer's disease J. Alzheimers Dis 41 2014 819 833 10.3233/JAD-140309
    • (2014) J. Alzheimers Dis , vol.41 , pp. 819-833
    • Vermeiren, Y.1    Van Dam, D.2    Aerts, T.3    Engelborghs, S.4    De Deyn, P.P.5
  • 93
    • 82055166108 scopus 로고    scopus 로고
    • Frontotemporal atrophy associated with paranoid delusions in women with Alzheimer's disease
    • D. Whitehead, C. Tunnard, C. Hurt, L.O. Wahlund, P. Mecocci, M. Tsolaki, and et al. Frontotemporal atrophy associated with paranoid delusions in women with Alzheimer's disease Int. Psychogeriatr 24 2012 99 107 10.1017/S1041610211000974
    • (2012) Int. Psychogeriatr , vol.24 , pp. 99-107
    • Whitehead, D.1    Tunnard, C.2    Hurt, C.3    Wahlund, L.O.4    Mecocci, P.5    Tsolaki, M.6
  • 94
    • 84888637323 scopus 로고    scopus 로고
    • Are apathy and depression independently associated with longitudinal trajectories of cortical atrophy in mild cognitive impairment?
    • L.B. Zahodne, A. Gongvatana, R.A. Cohen, B.R. Ott, G. Tremont Alzheimer's Disease Neuroimaging Initiative Are apathy and depression independently associated with longitudinal trajectories of cortical atrophy in mild cognitive impairment? Am. J. Geriatr. Psychiatry 21 2013 1098 1106 10.1016/j.jagp.2013.01.043
    • (2013) Am. J. Geriatr. Psychiatry , vol.21 , pp. 1098-1106
    • Zahodne, L.B.1    Gongvatana, A.2    Cohen, R.A.3    Ott, B.R.4    Tremont, G.5
  • 95
    • 84901419815 scopus 로고    scopus 로고
    • Functional magnetic resonance imaging study of apathy in Alzheimer's disease
    • Zhao H., Tang W., Xu X., Zhao Z., and Huang L. Functional magnetic resonance imaging study of apathy in Alzheimer's disease J. Neuropsychiatry Clin. Neurosci 2014 10.1176/appi.neuropsych.12110261
    • (2014) J. Neuropsychiatry Clin. Neurosci
    • Zhao, H.1    Tang, W.2    Xu, X.3    Zhao, Z.4    Huang, L.5
  • 96
    • 84896358989 scopus 로고    scopus 로고
    • Network dysfunction in Alzheimer's disease and frontotemporal dementia: Implications for psychiatry
    • Zhou J., and W.W. Seeley Network dysfunction in Alzheimer's disease and frontotemporal dementia: implications for psychiatry Biol. Psychiatry 75 2014 565 573 10.1016/j.biopsych.2014.01.020
    • (2014) Biol. Psychiatry , vol.75 , pp. 565-573
    • Zhou, J.1    Seeley, W.W.2
  • 97
    • 77951921512 scopus 로고    scopus 로고
    • Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer's disease
    • Zhou J., M.D. Greicius, E.D. Gennatas, M.E. Growdon, J.Y. Jang, G.D. Rabinovici, and et al. Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer's disease Brain 133 2010 1352 1367 10.1093/brain/awq075
    • (2010) Brain , vol.133 , pp. 1352-1367
    • Zhou, J.1    Greicius, M.D.2    Gennatas, E.D.3    Growdon, M.E.4    Jang, J.Y.5    Rabinovici, G.D.6


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