-
1
-
-
18244394595
-
Integrins play a critical role in mechanical stress-induced p38 MAPK activation
-
Aikawa R, Nagai T, Kudoh S, Zou Y, Tanaka M, Tamura M, Akazawa H, Takano H, Nagai R, Komuro I,. 2002. Integrins play a critical role in mechanical stress-induced p38 MAPK activation. Hypertension 39: 233-238.
-
(2002)
Hypertension
, vol.39
, pp. 233-238
-
-
Aikawa, R.1
Nagai, T.2
Kudoh, S.3
Zou, Y.4
Tanaka, M.5
Tamura, M.6
Akazawa, H.7
Takano, H.8
Nagai, R.9
Komuro, I.10
-
2
-
-
0036133646
-
Tumor necrosis factor-alpha converting enzyme
-
Black RA,. 2002. Tumor necrosis factor-alpha converting enzyme. Int J Biochem Cell Biol 34: 1-5.
-
(2002)
Int J Biochem Cell Biol
, vol.34
, pp. 1-5
-
-
Black, R.A.1
-
3
-
-
0030834283
-
Metalloprotease-disintegrins: Links to cell adhesion and cleavage of TNF alpha and Notch
-
Blobel CP,. 1997. Metalloprotease-disintegrins: Links to cell adhesion and cleavage of TNF alpha and Notch. Cell 90: 589-592.
-
(1997)
Cell
, vol.90
, pp. 589-592
-
-
Blobel, C.P.1
-
4
-
-
0035957036
-
Results of targeted anti-tumor necrosis factor therapy with etanercept (ENBREL) in patients with advanced heart failure
-
Bozkurt B, Torre-Amione G, Warren MS, Whitmore J, Soran OZ, Feldman AM, Mann DL,. 2001. Results of targeted anti-tumor necrosis factor therapy with etanercept (ENBREL) in patients with advanced heart failure. Circulation 103: 1044-1047.
-
(2001)
Circulation
, vol.103
, pp. 1044-1047
-
-
Bozkurt, B.1
Torre-Amione, G.2
Warren, M.S.3
Whitmore, J.4
Soran, O.Z.5
Feldman, A.M.6
Mann, D.L.7
-
5
-
-
34250669605
-
TNF-alpha regulates myogenesis and muscle regeneration by activating p38 MAPK
-
Chen SE, Jin B, Li YP,. 2007. TNF-alpha regulates myogenesis and muscle regeneration by activating p38 MAPK. Am J Physiol Cell Physiol 292: C1660-C1671.
-
(2007)
Am J Physiol Cell Physiol
, vol.292
, pp. C1660-C1671
-
-
Chen, S.E.1
Jin, B.2
Li, Y.P.3
-
6
-
-
0034604623
-
P38 MAPK and NF-kappa B collaborate to induce interleukin-6 gene expression and release. Evidence for a cytoprotective autocrine signaling pathway in a cardiac myocyte model system
-
Craig R, Larkin A, Mingo AM, Thuerauf DJ, Andrews C, McDonough PM, Glembotski CC,. 2000. P38 MAPK and NF-kappa B collaborate to induce interleukin-6 gene expression and release. Evidence for a cytoprotective autocrine signaling pathway in a cardiac myocyte model system. J Biol Chem 275: 23814-23824.
-
(2000)
J Biol Chem
, vol.275
, pp. 23814-23824
-
-
Craig, R.1
Larkin, A.2
Mingo, A.M.3
Thuerauf, D.J.4
Andrews, C.5
McDonough, P.M.6
Glembotski, C.C.7
-
7
-
-
36849008272
-
P38 and ERK1/2 MAPKs mediate the interplay of TNF-alpha and IL-10 in regulating oxidative stress and cardiac myocyte apoptosis
-
Dhingra S, Sharma AK, Singla DK, Singal PK,. 2007. P38 and ERK1/2 MAPKs mediate the interplay of TNF-alpha and IL-10 in regulating oxidative stress and cardiac myocyte apoptosis. Am J Physiol Heart Circ Physiol 293: H3524-H3531.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.293
, pp. H3524-H3531
-
-
Dhingra, S.1
Sharma, A.K.2
Singla, D.K.3
Singal, P.K.4
-
8
-
-
0035985185
-
Extracellular signal-regulated kinase phosphorylates tumor necrosis factor alpha-converting enzyme at threonine 735: A potential role in regulated shedding
-
Diaz-Rodriguez E, Montero JC, Esparis-Ogando A, Yuste L, Pandiella A,. 2002. Extracellular signal-regulated kinase phosphorylates tumor necrosis factor alpha-converting enzyme at threonine 735: A potential role in regulated shedding. Mol Biol Cell 13: 2031-2044.
-
(2002)
Mol Biol Cell
, vol.13
, pp. 2031-2044
-
-
Diaz-Rodriguez, E.1
Montero, J.C.2
Esparis-Ogando, A.3
Yuste, L.4
Pandiella, A.5
-
9
-
-
0042859853
-
Targeted overexpression of transmembrane tumor necrosis factor provokes a concentric cardiac hypertrophic phenotype
-
Dibbs ZI, Diwan A, Nemoto S, DeFreitas G, Abdellatif M, Carabello BA, Spinale FG, Feuerstein G, Sivasubramanian N, Mann DL,. 2003. Targeted overexpression of transmembrane tumor necrosis factor provokes a concentric cardiac hypertrophic phenotype. Circulation 108: 1002-1008.
-
(2003)
Circulation
, vol.108
, pp. 1002-1008
-
-
Dibbs, Z.I.1
Diwan, A.2
Nemoto, S.3
DeFreitas, G.4
Abdellatif, M.5
Carabello, B.A.6
Spinale, F.G.7
Feuerstein, G.8
Sivasubramanian, N.9
Mann, D.L.10
-
10
-
-
1642576138
-
Targeted overexpression of noncleavable and secreted forms of tumor necrosis factor provokes disparate cardiac phenotypes
-
Diwan A, Dibbs Z, Nemoto S, DeFreitas G, Carabello BA, Sivasubramanian N, Wilson EM, Spinale FG, Mann DL,. 2004. Targeted overexpression of noncleavable and secreted forms of tumor necrosis factor provokes disparate cardiac phenotypes. Circulation 109: 262-268.
-
(2004)
Circulation
, vol.109
, pp. 262-268
-
-
Diwan, A.1
Dibbs, Z.2
Nemoto, S.3
DeFreitas, G.4
Carabello, B.A.5
Sivasubramanian, N.6
Wilson, E.M.7
Spinale, F.G.8
Mann, D.L.9
-
11
-
-
0038719741
-
Characterization of growth factor-induced serine phosphorylation of tumor necrosis factor-alpha converting enzyme and of an alternatively translated polypeptide
-
Fan H, Turck CW, Derynck R,. 2003. Characterization of growth factor-induced serine phosphorylation of tumor necrosis factor-alpha converting enzyme and of an alternatively translated polypeptide. J Biol Chem 278: 18617-18627.
-
(2003)
J Biol Chem
, vol.278
, pp. 18617-18627
-
-
Fan, H.1
Turck, C.W.2
Derynck, R.3
-
12
-
-
6444240024
-
TIMP-3 deficiency leads to dilated cardiomyopathy
-
Fedak PW, Smookler DS, Kassiri Z, Ohno N, Leco KJ, Verma S, Mickle DA, Watson KL, Hojilla CV, Cruz W, Weisel RD, Li RK, Khokha R,. 2004. TIMP-3 deficiency leads to dilated cardiomyopathy. Circulation 110: 2401-2409.
-
(2004)
Circulation
, vol.110
, pp. 2401-2409
-
-
Fedak, P.W.1
Smookler, D.S.2
Kassiri, Z.3
Ohno, N.4
Leco, K.J.5
Verma, S.6
Mickle, D.A.7
Watson, K.L.8
Hojilla, C.V.9
Cruz, W.10
Weisel, R.D.11
Li, R.K.12
Khokha, R.13
-
13
-
-
0034730790
-
Early activation of the multicomponent signaling complex associated with focal adhesion kinase induced by pressure overload in the rat heart
-
Franchini KG, Torsoni AS, Soares PH, Saad MJ,. 2000. Early activation of the multicomponent signaling complex associated with focal adhesion kinase induced by pressure overload in the rat heart. Circ Res 87: 558-565.
-
(2000)
Circ Res
, vol.87
, pp. 558-565
-
-
Franchini, K.G.1
Torsoni, A.S.2
Soares, P.H.3
Saad, M.J.4
-
14
-
-
79957483071
-
TNF-alpha induced apoptosis is accompanied with rapid CD30 and slower CD45 shedding from K-562 cells
-
Jurisic V, Srdic-Rajic T, Konjevic G, Bogdanovic G, Colic M,. 2011. TNF-alpha induced apoptosis is accompanied with rapid CD30 and slower CD45 shedding from K-562 cells. J Membr Biol 239: 115-122.
-
(2011)
J Membr Biol
, vol.239
, pp. 115-122
-
-
Jurisic, V.1
Srdic-Rajic, T.2
Konjevic, G.3
Bogdanovic, G.4
Colic, M.5
-
15
-
-
67651100871
-
Tissue-specific deletion of the coxsackievirus and adenovirus receptor protects mice from virus-induced pancreatitis and myocarditis
-
Kallewaard NL, Zhang L, Chen JW, Guttenberg M, Sanchez MD, Bergelson JM,. 2009. Tissue-specific deletion of the coxsackievirus and adenovirus receptor protects mice from virus-induced pancreatitis and myocarditis. Cell Host Microbe 6: 91-98.
-
(2009)
Cell Host Microbe
, vol.6
, pp. 91-98
-
-
Kallewaard, N.L.1
Zhang, L.2
Chen, J.W.3
Guttenberg, M.4
Sanchez, M.D.5
Bergelson, J.M.6
-
16
-
-
24044458235
-
Combination of tumor necrosis factor-alpha ablation and matrix metalloproteinase inhibition prevents heart failure after pressure overload in tissue inhibitor of metalloproteinase-3 knock-out mice
-
Kassiri Z, Oudit GY, Sanchez O, Dawood F, Mohammed FF, Nuttall RK, Edwards DR, Liu PP, Backx PH, Khokha R,. 2005. Combination of tumor necrosis factor-alpha ablation and matrix metalloproteinase inhibition prevents heart failure after pressure overload in tissue inhibitor of metalloproteinase-3 knock-out mice. Circ Res 97: 380-390.
-
(2005)
Circ Res
, vol.97
, pp. 380-390
-
-
Kassiri, Z.1
Oudit, G.Y.2
Sanchez, O.3
Dawood, F.4
Mohammed, F.F.5
Nuttall, R.K.6
Edwards, D.R.7
Liu, P.P.8
Backx, P.H.9
Khokha, R.10
-
17
-
-
0034713820
-
Left ventricular hypertrophy: Pathogenesis, detection, and prognosis
-
Lorell BH, Carabello BA,. 2000. Left ventricular hypertrophy: Pathogenesis, detection, and prognosis. Circulation 102: 470-479.
-
(2000)
Circulation
, vol.102
, pp. 470-479
-
-
Lorell, B.H.1
Carabello, B.A.2
-
18
-
-
0036951909
-
Tumor necrosis factor-induced signal transduction and left ventricular remodeling
-
Mann DL,. 2002. Tumor necrosis factor-induced signal transduction and left ventricular remodeling. J Card Fail 8: S379-S386.
-
(2002)
J Card Fail
, vol.8
, pp. S379-S386
-
-
Mann, D.L.1
-
19
-
-
19944386296
-
Targeted anticytokine therapy and the failing heart
-
discussion 38C-40C
-
Mann DL,. 2005. Targeted anticytokine therapy and the failing heart. Am J Cardiol. 95: 9C-16C; discussion 38C-40C.
-
(2005)
Am J Cardiol
, vol.95
, pp. 9C-16C
-
-
Mann, D.L.1
-
20
-
-
0024409475
-
Load regulation of the properties of adult feline cardiocytes: Growth induction by cellular deformation
-
Mann DL, Kent RL,. 1989. Load regulation of the properties of adult feline cardiocytes: Growth induction by cellular deformation. Circ Res 64: 1079-1090.
-
(1989)
Circ Res
, vol.64
, pp. 1079-1090
-
-
Mann, D.L.1
Kent, R.L.2
-
21
-
-
67349226089
-
Identification of ADAM10 as a major TNF sheddase in ADAM17-deficient fibroblasts
-
Mezyk-Kopec R, Bzowska M, Stalinska K, Chelmicki T, Podkalicki M, Jucha J, Kowalczyk K, Mak P, Bereta J,. 2009. Identification of ADAM10 as a major TNF sheddase in ADAM17-deficient fibroblasts. Cytokine 46: 309-315.
-
(2009)
Cytokine
, vol.46
, pp. 309-315
-
-
Mezyk-Kopec, R.1
Bzowska, M.2
Stalinska, K.3
Chelmicki, T.4
Podkalicki, M.5
Jucha, J.6
Kowalczyk, K.7
Mak, P.8
Bereta, J.9
-
22
-
-
8044250278
-
Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha
-
Moss ML, Jin SL, Milla ME, Bickett DM, Burkhart W, Carter HL, Chen WJ, Clay WC, Didsbury JR, Hassler D, Hoffman CR, Kost TA, Lambert MH, Leesnitzer MA, McCauley P, McGeehan G, Mitchell J, Moyer M, Pahel G, Rocque W, Overton LK, Schoenen F, Seaton T, Su JL, Becherer JD, et al., 1997. Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha. Nature 385: 733-736.
-
(1997)
Nature
, vol.385
, pp. 733-736
-
-
Moss, M.L.1
Jin, S.L.2
Milla, M.E.3
Bickett, D.M.4
Burkhart, W.5
Carter, H.L.6
Chen, W.J.7
Clay, W.C.8
Didsbury, J.R.9
Hassler, D.10
Hoffman, C.R.11
Kost, T.A.12
Lambert, M.H.13
Leesnitzer, M.A.14
McCauley, P.15
McGeehan, G.16
Mitchell, J.17
Moyer, M.18
Pahel, G.19
Rocque, W.20
Overton, L.K.21
Schoenen, F.22
Seaton, T.23
Su, J.L.24
Becherer, J.D.25
more..
-
23
-
-
84872736716
-
Novel methods and strategies in the discovery of TACE inhibitors
-
Murumkar PR, Giridhar R, Yadav MR,. 2013. Novel methods and strategies in the discovery of TACE inhibitors. Expert Opin Drug Discov 8: 157-181.
-
(2013)
Expert Opin Drug Discov
, vol.8
, pp. 157-181
-
-
Murumkar, P.R.1
Giridhar, R.2
Yadav, M.R.3
-
24
-
-
84885455035
-
Src mediates the mechanical activation of myogenesis by activating TNFalpha-converting enzyme
-
Niu A, Wen Y, Liu H, Zhan M, Jin B, Li YP,. 2013. Src mediates the mechanical activation of myogenesis by activating TNFalpha-converting enzyme. J Cell Sci 126: 4349-4357.
-
(2013)
J Cell Sci
, vol.126
, pp. 4349-4357
-
-
Niu, A.1
Wen, Y.2
Liu, H.3
Zhan, M.4
Jin, B.5
Li, Y.P.6
-
25
-
-
0032515018
-
An essential role for ectodomain shedding in mammalian development
-
Peschon JJ, Slack JL, Reddy P, Stocking KL, Sunnarborg SW, Lee DC, Russell WE, Castner BJ, Johnson RS, Fitzner JN, Boyce RW, Nelson N, Kozlosky CJ, Wolfson MF, Rauch CT, Cerretti DP, Paxton RJ, March CJ, Black RA,. 1998. An essential role for ectodomain shedding in mammalian development. Science 282: 1281-1284.
-
(1998)
Science
, vol.282
, pp. 1281-1284
-
-
Peschon, J.J.1
Slack, J.L.2
Reddy, P.3
Stocking, K.L.4
Sunnarborg, S.W.5
Lee, D.C.6
Russell, W.E.7
Castner, B.J.8
Johnson, R.S.9
Fitzner, J.N.10
Boyce, R.W.11
Nelson, N.12
Kozlosky, C.J.13
Wolfson, M.F.14
Rauch, C.T.15
Cerretti, D.P.16
Paxton, R.J.17
March, C.J.18
Black, R.A.19
-
26
-
-
78650674716
-
Cyclic GMP and protein kinase G control a Src-containing mechanosome in osteoblasts
-
ra
-
Rangaswami H, Schwappacher R, Marathe N, Zhuang S, Casteel DE, Haas B, Chen Y, Pfeifer A, Kato H, Shattil S, Boss GR, Pilz RB,. 2010. Cyclic GMP and protein kinase G control a Src-containing mechanosome in osteoblasts. Sci Signal 3: ra 91.
-
(2010)
Sci Signal
, vol.3
, pp. 91
-
-
Rangaswami, H.1
Schwappacher, R.2
Marathe, N.3
Zhuang, S.4
Casteel, D.E.5
Haas, B.6
Chen, Y.7
Pfeifer, A.8
Kato, H.9
Shattil, S.10
Boss, G.R.11
Pilz, R.B.12
-
27
-
-
0034640286
-
Functional analysis of the domain structure of tumor necrosis factor-alpha converting enzyme
-
Reddy P, Slack JL, Davis R, Cerretti DP, Kozlosky CJ, Blanton RA, Shows D, Peschon JJ, Black RA,. 2000. Functional analysis of the domain structure of tumor necrosis factor-alpha converting enzyme. J Biol Chem 275: 14608-14614.
-
(2000)
J Biol Chem
, vol.275
, pp. 14608-14614
-
-
Reddy, P.1
Slack, J.L.2
Davis, R.3
Cerretti, D.P.4
Kozlosky, C.J.5
Blanton, R.A.6
Shows, D.7
Peschon, J.J.8
Black, R.A.9
-
28
-
-
78149478401
-
Mitogen-activated protein kinase signaling in the heart: Angels versus demons in a heart-breaking tale
-
Rose BA, Force T, Wang Y,. 2010. Mitogen-activated protein kinase signaling in the heart: Angels versus demons in a heart-breaking tale. Physiol Rev 90: 1507-1546.
-
(2010)
Physiol Rev
, vol.90
, pp. 1507-1546
-
-
Rose, B.A.1
Force, T.2
Wang, Y.3
-
29
-
-
0026709274
-
Molecular characterization of the stretch-induced adaptation of cultured cardiac cells. An in vitro model of load-induced cardiac hypertrophy
-
Sadoshima J, Jahn L, Takahashi T, Kulik TJ, Izumo S,. 1992. Molecular characterization of the stretch-induced adaptation of cultured cardiac cells. An in vitro model of load-induced cardiac hypertrophy. J Biol Chem 267: 10551-10560.
-
(1992)
J Biol Chem
, vol.267
, pp. 10551-10560
-
-
Sadoshima, J.1
Jahn, L.2
Takahashi, T.3
Kulik, T.J.4
Izumo, S.5
-
30
-
-
0033614842
-
Tumor necrosis factor-alpha-converting enzyme and tumor necrosis factor-alpha in human dilated cardiomyopathy
-
Satoh M, Nakamura M, Saitoh H, Satoh H, Maesawa C, Segawa I, Tashiro A, Hiramori K,. 1999. Tumor necrosis factor-alpha-converting enzyme and tumor necrosis factor-alpha in human dilated cardiomyopathy. Circulation 99: 3260-3265.
-
(1999)
Circulation
, vol.99
, pp. 3260-3265
-
-
Satoh, M.1
Nakamura, M.2
Saitoh, H.3
Satoh, H.4
Maesawa, C.5
Segawa, I.6
Tashiro, A.7
Hiramori, K.8
-
31
-
-
21044444181
-
ERK-mediated phosphorylation of Thr735 in TNFalpha-converting enzyme and its potential role in TACE protein trafficking
-
Soond SM, Everson B, Riches DW, Murphy G,. 2005. ERK-mediated phosphorylation of Thr735 in TNFalpha-converting enzyme and its potential role in TACE protein trafficking. J Cell Sci 118: 2371-2380.
-
(2005)
J Cell Sci
, vol.118
, pp. 2371-2380
-
-
Soond, S.M.1
Everson, B.2
Riches, D.W.3
Murphy, G.4
-
32
-
-
17944379672
-
Src and multiple MAP kinase activation in cardiac hypertrophy and congestive heart failure under chronic pressure-overload: Comparison with acute mechanical stretch
-
Takeishi Y, Huang Q, Abe J, Glassman M, Che W, Lee JD, Kawakatsu H, Lawrence EG, Hoit BD, Berk BC, Walsh RA,. 2001. Src and multiple MAP kinase activation in cardiac hypertrophy and congestive heart failure under chronic pressure-overload: comparison with acute mechanical stretch. J Mol Cell Cardiol 33: 1637-1648.
-
(2001)
J Mol Cell Cardiol
, vol.33
, pp. 1637-1648
-
-
Takeishi, Y.1
Huang, Q.2
Abe, J.3
Glassman, M.4
Che, W.5
Lee, J.D.6
Kawakatsu, H.7
Lawrence, E.G.8
Hoit, B.D.9
Berk, B.C.10
Walsh, R.A.11
-
33
-
-
0042266791
-
Focal adhesion kinase is activated and mediates the early hypertrophic response to stretch in cardiac myocytes
-
Torsoni AS, Constancio SS, Nadruz W, Jr., Hanks SK, Franchini KG,. 2003. Focal adhesion kinase is activated and mediates the early hypertrophic response to stretch in cardiac myocytes. Circ Res 93: 140-147.
-
(2003)
Circ Res
, vol.93
, pp. 140-147
-
-
Torsoni, A.S.1
Constancio, S.S.2
Nadruz, W.3
Hanks, S.K.4
Franchini, K.G.5
-
34
-
-
0026461874
-
Pleiotropic effects of TNF in infection and neoplasia: Beneficial, inflammatory, catabolic, or injurious
-
Tracey KJ, Cerami A,. 1992. Pleiotropic effects of TNF in infection and neoplasia: Beneficial, inflammatory, catabolic, or injurious. Immunol Ser 56: 431-452.
-
(1992)
Immunol ser
, vol.56
, pp. 431-452
-
-
Tracey, K.J.1
Cerami, A.2
-
35
-
-
84860662213
-
Serendipitous discovery of a novel protein signaling mechanism in heart failure
-
Vitello AM, Du Y, Buttrick PM, Walker LA,. 2012. Serendipitous discovery of a novel protein signaling mechanism in heart failure. Biochem Biophys Res Commun 421: 431-435.
-
(2012)
Biochem Biophys Res Commun
, vol.421
, pp. 431-435
-
-
Vitello, A.M.1
Du, Y.2
Buttrick, P.M.3
Walker, L.A.4
-
36
-
-
17844388845
-
Visualizing the mechanical activation of Src
-
Wang Y, Botvinick EL, Zhao Y, Berns MW, Usami S, Tsien RY, Chien S,. 2005. Visualizing the mechanical activation of Src. Nature 434: 1040-1045.
-
(2005)
Nature
, vol.434
, pp. 1040-1045
-
-
Wang, Y.1
Botvinick, E.L.2
Zhao, Y.3
Berns, M.W.4
Usami, S.5
Tsien, R.Y.6
Chien, S.7
-
37
-
-
33947315778
-
TACE release of TNF-alpha mediates mechanotransduction-induced activation of p38 MAPK and myogenesis
-
Zhan M, Jin B, Chen SE, Reecy JM, Li YP,. 2007. TACE release of TNF-alpha mediates mechanotransduction-induced activation of p38 MAPK and myogenesis. J Cell Sci 120: 692-701.
-
(2007)
J Cell Sci
, vol.120
, pp. 692-701
-
-
Zhan, M.1
Jin, B.2
Chen, S.E.3
Reecy, J.M.4
Li, Y.P.5
-
38
-
-
5644290647
-
Evaluation of the contribution of different ADAMs to tumor necrosis factor alpha (TNFalpha) shedding and of the function of the TNFalpha ectodomain in ensuring selective stimulated shedding by the TNFalpha convertase (TACE/ADAM17)
-
Zheng Y, Saftig P, Hartmann D, Blobel C,. 2004. Evaluation of the contribution of different ADAMs to tumor necrosis factor alpha (TNFalpha) shedding and of the function of the TNFalpha ectodomain in ensuring selective stimulated shedding by the TNFalpha convertase (TACE/ADAM17). J Biol Chem 279: 42898-42906.
-
(2004)
J Biol Chem
, vol.279
, pp. 42898-42906
-
-
Zheng, Y.1
Saftig, P.2
Hartmann, D.3
Blobel, C.4
|