Double-negative feedback loop between long non-coding RNA TUG1 and miR-145 promotes epithelial to mesenchymal transition and radioresistance in human bladder cancer cells

FEBS Letters

Volumn 589, Issue 20, 2015, Pages 3175-3181

  Tan, Jiemei ^a   Qiu, Kaifeng ^b   Li, Mingyi ^b   Liang, Ying ^c  

^a Affiliated Jiangmen Hospital of Sun Yat sen   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

Author keywords

Bladder cancer; Epithelial to mesenchymal transition; miR 145; Radioresistance; TUG1; ZEB2

Indexed keywords

ARGONAUTE 2 PROTEIN; LONG UNTRANSLATED RNA; LONG UNTRANSLATED RNA TUG1; MEMBRANE PROTEIN; MICRORNA 145; PROTEIN ZEB2; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; HOMEODOMAIN PROTEIN; MICRORNA; MIRN145 MICRORNA, HUMAN; REPRESSOR PROTEIN; TUG1 LONG NONCODING RNA, HUMAN; ZEB2 PROTEIN, HUMAN;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLADDER CANCER; BLADDER CANCER CELL LINE; CANCER INHIBITION; CELL INVASION; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; GENE FUNCTION; GENE OVEREXPRESSION; GENE REPRESSION; GENE SILENCING; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; RADIOSENSITIVITY; REGULATORY MECHANISM; TUMOR INVASION; UPREGULATION; AGED; BLADDER TUMOR; CELL LINE; FEEDBACK SYSTEM; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; MALE; METABOLISM; MIDDLE AGED; NUCLEOTIDE SEQUENCE; PATHOLOGY; RADIATION DOSE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SEQUENCE HOMOLOGY; TUMOR CELL LINE; VERY ELDERLY; WESTERN BLOTTING; XENOGRAFT;

3' UNTRANSLATED REGIONS; AGED; AGED, 80 AND OVER; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE; CELL LINE, TUMOR; EPITHELIAL-MESENCHYMAL TRANSITION; FEEDBACK, PHYSIOLOGICAL; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEK293 CELLS; HOMEODOMAIN PROTEINS; HUMANS; MALE; MICRORNAS; MIDDLE AGED; RADIATION TOLERANCE; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, LONG NONCODING; SEQUENCE HOMOLOGY, NUCLEIC ACID; TRANSPLANTATION, HETEROLOGOUS; URINARY BLADDER NEOPLASMS;

EID: 84943347915     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2015.08.020     Document Type: Article

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