The cluster of miR-143 and miR-145 affects the risk for esophageal squamous cell carcinoma through co-regulating fascin homolog 1

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Liu, Ran ^a   Liao, Juan ^a   Yang, Miao ^a   Sheng, Jingyi ^a   Yang, Hao ^a   Wang, Yi ^b   Pan, Enchun ^b   Guo, Wei ^c   Pu, Yuepu ^a   Kim, Sun Jung ^d   Yin, Lihong ^a  

^a SOUTHEAST UNIVERSITY   (China)

^b Huaian Center for Disease Control and Prevention   (China)

^c THE AFFILIATED HUAIAN NO 1 PEOPLE S HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^d Dongguk University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

FASCIN; FASCIN HOMOLOG 1; LUCIFERASE; MICRORNA; MICRORNA 143; MICRORNA 145; UNCLASSIFIED DRUG; ACTIN BINDING PROTEIN; CARRIER PROTEIN; FSCN1 PROTEIN, HUMAN; MIRN143 MICRORNA, HUMAN; MIRN145 MICRORNA, HUMAN;

3' UNTRANSLATED REGION; ADULT; ARTICLE; CANCER CELL CULTURE; CANCER PATIENT; CANCER RISK; CANCER TISSUE; CONTROLLED STUDY; EARLY DIAGNOSIS; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; ESOPHAGUS SURGERY; FEMALE; GENE CLUSTER; GENE EXPRESSION; GENE FUNCTION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; PROGNOSIS; PROTEIN TARGETING; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; AGED; ESOPHAGUS TUMOR; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; SQUAMOUS CELL CARCINOMA; TUMOR CELL LINE; VALIDATION STUDY;

AGED; CARCINOMA, SQUAMOUS CELL; CARRIER PROTEINS; CELL LINE, TUMOR; ESOPHAGEAL NEOPLASMS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MICROFILAMENT PROTEINS; MICRORNAS; MIDDLE AGED;

EID: 84863357527     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033987     Document Type: Article

References (46)

1. Garzon R, Calin GA, Croce CM, (2009) MicroRNAs in Cancer. Annu Rev Med 60: 167-179.
2. Bartel DP, (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297.
3. Ambros V, (2004) The functions of animal microRNAs. Nature 431: 350-355.
4. Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, et al. (2005) MicroRNA expression profiles classify human cancers. Nature 435: 834-838.
5. Manikandan J, Aarthi JJ, Kumar SD, Pushparaj PN, (2008) Oncomirs: the potential role of non-coding microRNAs in understanding cancer. Bioinformation 2: 330-334.
6. Schetter AJ, Heegaard NH, Harris CC, (2010) Inflammation and cancer: interweaving microRNA, free radical, cytokine and p53 pathways. Carcinogenesis 31: 37-49.
7. Kwak PB, Iwasaki S, Tomari Y, (2010) The microRNA pathway and cancer. Cancer Sci 101: 2309-2315.
8. Bonauer A, Dimmeler S, (2009) The microRNA-17-92 cluster: still a miRacle? Cell Cycle 8: 3866-3873.
9. Kim YK, Yu J, Han TS, Park SY, Namkoong B, et al. (2009) Functional links between clustered microRNAs: suppression of cell-cycle inhibitors by microRNA clusters in gastric cancer. Nucleic Acids Res 37: 1672-1681.
10. Tanzer A, Stadler PF, (2004) Molecular evolution of a microRNA cluster. J Mol Biol 339: 327-335.
11. Slaby O, Svoboda M, Fabian P, Smerdova T, Knoflickova D, et al. (2007) Altered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancer. Oncology 72: 397-402.
12. Fuse M, Nohata N, Kojima S, Sakamoto S, Chiyomaru T, et al. (2011) Restoration of miR-145 expression suppresses cell proliferation, migration and invasion in prostate cancer by targeting FSCN1. Int J Oncol 38: 1093-1101.
13. Kano M, Seki N, Kikkawa N, Fujimura L, Hoshino I, et al. (2010) miR-145, miR-133a and miR-133b: Tumor-suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma. Int J Cancer 127: 2804-2814.
14. Chiyomaru T, Tatarano S, Kawakami K, Enokida H, Yoshino H, et al. (2011) SWAP70, actin-binding protein, function as an oncogene targeting tumor-suppressive miR-145 in prostate cancer. Prostate.
15. Chiyomaru T, Enokida H, Tatarano S, Kawahara K, Uchida Y, et al. (2010) miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer. Br J Cancer 102: 883-891.
16. Spizzo R, Nicoloso MS, Lupini L, Lu Y, Fogarty J, et al. (2010) miR-145 participates with TP53 in a death-promoting regulatory loop and targets estrogen receptor-alpha in human breast cancer cells. Cell Death Differ 17: 246-254.
17. Zhu H, Dougherty U, Robinson V, Mustafi R, Pekow J, et al. (2011) EGFR Signals Downregulate Tumor Suppressors miR-143 and miR-145 in Western Diet-Promoted Murine Colon Cancer: Role of G1 Regulators. Mol Cancer Res 9: 960-975.
18. Xu B, Niu X, Zhang X, Tao J, Wu D, et al. (2011) miR-143 decreases prostate cancer cells proliferation and migration and enhances their sensitivity to docetaxel through suppression of KRAS. Mol Cell Biochem 350: 207-213.
19. Hu N, Roth MJ, Polymeropolous M, Tang ZZ, Emmert-Buck MR, et al. (2000) Identification of novel regions of allelic loss from a genomewide scan of esophageal squamous-cell carcinoma in a high-risk Chinese population. Genes Chromosomes Cancer 27: 217-228.
20. Mayama T, Fukushige S, Shineha R, Nishihira T, Satomi S, et al. (2000) Frequent loss of copy number on the long arm of chromosome 21 in human esophageal squamous cell carcinoma. Int J Oncol 17: 245-252.
21. Montesano R, Hollstein M, Hainaut P, (1996) Genetic alterations in esophageal cancer and their relevance to etiology and pathogenesis: a review. Int J Cancer 69: 225-235.
22. Moskaluk CA, Hu J, Perlman EJ, (1998) Comparative genomic hybridization of esophageal and gastroesophageal adenocarcinomas shows consensus areas of DNA gain and loss. Genes Chromosomes Cancer 22: 305-311.
23. Pack SD, Karkera JD, Zhuang Z, Pak ED, Balan KV, et al. (1999) Molecular cytogenetic fingerprinting of esophageal squamous cell carcinoma by comparative genomic hybridization reveals a consistent pattern of chromosomal alterations. Genes Chromosomes Cancer 25: 160-168.
24. Peralta RC, Casson AG, Wang RN, Keshavjee S, Redston M, et al. (1998) Distinct regions of frequent loss of heterozygosity of chromosome 5p and 5q in human esophageal cancer. Int J Cancer 78: 600-605.
25. Yen CC, Chen YJ, Chen JT, Hsia JY, Chen PM, et al. (2001) Comparative genomic hybridization of esophageal squamous cell carcinoma: correlations between chromosomal aberrations and disease progression/prognosis. Cancer 92: 2769-2777.
26. Chang YC, Yeh KT, Liu TC, Chang JG, (2010) Molecular cytogenetic characterization of esophageal cancer detected by comparative genomic hybridization. J Clin Lab Anal 24: 167-174.
27. Jayo A, Parsons M, (2010) Fascin: a key regulator of cytoskeletal dynamics. Int J Biochem Cell Biol 42: 1614-1617.
28. Adams JC, (2004) Roles of fascin in cell adhesion and motility. Curr Opin Cell Biol 16: 590-596.
29. Darnel AD, Behmoaram E, Vollmer RT, Corcos J, Bijian K, et al. (2009) Fascin regulates prostate cancer cell invasion and is associated with metastasis and biochemical failure in prostate cancer. Clin Cancer Res 15: 1376-1383.
30. Maitra A, Iacobuzio-Donahue C, Rahman A, Sohn TA, Argani P, et al. (2002) Immunohistochemical validation of a novel epithelial and a novel stromal marker of pancreatic ductal adenocarcinoma identified by global expression microarrays: sea urchin fascin homolog and heat shock protein 47. Am J Clin Pathol 118: 52-59.
31. Pelosi G, Pasini F, Fraggetta F, Pastorino U, Iannucci A, et al. (2003) Independent value of fascin immunoreactivity for predicting lymph node metastases in typical and atypical pulmonary carcinoids. Lung Cancer 42: 203-213.
32. Hashimoto Y, Shimada Y, Kawamura J, Yamasaki S, Imamura M, (2004) The prognostic relevance of fascin expression in human gastric carcinoma. Oncology 67: 262-270.
33. Hashimoto Y, Skacel M, Adams JC, (2005) Roles of fascin in human carcinoma motility and signaling: prospects for a novel biomarker? Int J Biochem Cell Biol 37: 1787-1804.
34. Rodriguez-Pinilla SM, Sarrio D, Honrado E, Hardisson D, Calero F, et al. (2006) Prognostic significance of basal-like phenotype and fascin expression in node-negative invasive breast carcinomas. Clin Cancer Res 12: 1533-1539.
35. Zigeuner R, Droschl N, Tauber V, Rehak P, Langner C, (2006) Biologic significance of fascin expression in clear cell renal cell carcinoma: systematic analysis of primary and metastatic tumor tissues using a tissue microarray technique. Urology 68: 518-522.
36. Hashimoto Y, Ito T, Inoue H, Okumura T, Tanaka E, et al. (2005) Prognostic significance of fascin overexpression in human esophageal squamous cell carcinoma. Clin Cancer Res 11: 2597-2605.
37. Takikita M, Hu N, Shou JZ, Giffen C, Wang QH, et al. (2011) Fascin and CK4 as biomarkers for esophageal squamous cell carcinoma. Anticancer Res 31: 945-952.
38. Xie JJ, Xu LY, Zhang HH, Cai WJ, Mai RQ, et al. (2005) Role of fascin in the proliferation and invasiveness of esophageal carcinoma cells. Biochem Biophys Res Commun 337: 355-362.
39. Zhang H, Xu L, Xiao D, Xie J, Zeng H, et al. (2006) Fascin is a potential biomarker for early-stage oesophageal squamous cell carcinoma. J Clin Pathol 59: 958-964.
40. Brow DA, Guthrie C, (1988) Spliceosomal RNA U6 is remarkably conserved from yeast to mammals. Nature 334: 213-218.
41. Calin GA, Sevignani C, Dumitru CD, Hyslop T, Noch E, et al. (2004) Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci U S A 101: 2999-3004.
42. Cho WC, Chow AS, Au JS, (2009) Restoration of tumour suppressor hsa-miR-145 inhibits cancer cell growth in lung adenocarcinoma patients with epidermal growth factor receptor mutation. Eur J Cancer 45: 2197-2206.
43. Radojicic J, Zaravinos A, Vrekoussis T, Kafousi M, Spandidos DA, et al. (2011) MicroRNA expression analysis in triple-negative (ER, PR and Her2/neu) breast cancer. Cell Cycle 10: 507-517.
44. Takagi T, Iio A, Nakagawa Y, Naoe T, Tanigawa N, et al. (2009) Decreased expression of microRNA-143 and-145 in human gastric cancers. Oncology 77: 12-21.
45. Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
46. Lewis BP, Burge CB, Bartel DP, (2005) Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120: 15-20.