Neutrophil elastase promotes interleukin-1β secretion from human coronary endothelium

Journal of Biological Chemistry

Volumn 290, Issue 40, 2015, Pages 24067-24078

  Alfaidi, Mabruka ^a   Wilson, Heather ^a   Daigneault, Marc ^a   Burnett, Amanda ^a   Ridger, Victoria ^a   Chamberlain, Janet ^a   Francis, Sheila ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; AMINO ACIDS; ENDOTHELIAL CELLS; HEART;

ATHEROSCLEROTIC PLAQUE; CORONARY ARTERIES; INFLAMMATORY MEDIATORS; INFLAMMATORY PROCESS; INTRACELLULAR CA; ISCHEMIC HEART DISEASE; MULTIVESICULAR BODIES; THERAPEUTIC TARGETS;

DISEASES;

CALCIUM ION; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LEUKOCYTE ELASTASE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; APOLIPOPROTEIN E; CALCIUM; IL1B PROTEIN, HUMAN; IL1B PROTEIN, MOUSE;

ARTICLE; ATHEROSCLEROTIC PLAQUE; CONTROLLED STUDY; CORONARY ARTERY; CYTOKINE RELEASE; ENDOTHELIUM CELL; ENZYME ACTIVITY; EXOSOME; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SECRETION; VASCULAR ENDOTHELIUM; ANIMAL; APOPTOSIS; CELL CULTURE; CELL SURVIVAL; CORONARY BLOOD VESSEL; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; METABOLISM; MICROCIRCULATION; MOUSE; PHOSPHORYLATION; TRANSGENIC MOUSE;

ANIMALS; APOLIPOPROTEINS E; APOPTOSIS; CALCIUM; CELL SURVIVAL; CELLS, CULTURED; CORONARY VESSELS; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTERLEUKIN-1BETA; LEUKOCYTE ELASTASE; MALE; MICE; MICE, TRANSGENIC; MICROCIRCULATION; PHOSPHORYLATION; PLAQUE, ATHEROSCLEROTIC;

EID: 84943328548     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.659029     Document Type: Article

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