Interleukin-1β enhances FasL-induced caspase-3/-7 activity without increasing apoptosis in primary mouse hepatocytes

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Lutz, Anna ^a   Sanwald, Julia ^b   Thomas, Maria ^c   Feuer, Ronny ^b   Sawodny, Oliver ^b   Ederer, Michael ^b   Borner, Christoph ^a   Humar, Matjaz ^a   Merfort, Irmgard ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF STUTTGART   (Germany)

^c DR MARGARETE FISCHER BOSCH INSTITUTE OF CLINICAL PHARMACOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BH3 PROTEIN; BIM PROTEIN; CASPASE 3; CASPASE 7; COMPLEMENTARY DNA; CYTOCHROME C; FAS LIGAND; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; PROTEIN BID; STRESS ACTIVATED PROTEIN KINASE; X LINKED INHIBITOR OF APOPTOSIS; APOPTOSIS REGULATORY PROTEIN; BCL-2-LIKE PROTEIN 11; MEMBRANE PROTEIN; ONCOPROTEIN; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BINDING SITE; CELL HETEROGENEITY; CELL POPULATION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA SYNTHESIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; IMMUNOBLOTTING; LIVER CELL; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION; ANIMAL; BIOLOGICAL MODEL; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; METABOLISM; SECRETION (PROCESS);

MURINAE;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CASPASE 3; CASPASE 7; CELL SURVIVAL; CYTOCHROMES C; ENZYME ACTIVATION; FAS LIGAND PROTEIN; HEPATOCYTES; INTERLEUKIN-1BETA; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MEMBRANE PROTEINS; MICE; MODELS, BIOLOGICAL; NF-KAPPA B; PROTO-ONCOGENE PROTEINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84920399901     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0115603     Document Type: Article

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