Microprocessor complex subunit digeorge syndrome critical region gene 8 (DGCR8) is required for Schwann cell myelination and myelin maintenance

Journal of Biological Chemistry

Volumn 290, Issue 40, 2015, Pages 24294-24307

  Lin, Hsin Pin ^a   Oksuz, Idil ^a   Hurley, Edward ^b   Wrabetz, Lawrence ^b   Awatramani, Rajeshwar ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; GENES; MAINTENANCE; MICROPROCESSOR CHIPS; NEURONS; TRANSCRIPTION;

CRITICAL REGION; DEVELOPMENT RESULTS; EARLY GROWTH; MACROPHAGE INFILTRATIONS; MYELIN SHEATHS; MYELINATION; SCHWANN CELLS; SONIC HEDGEHOGS;

GENE EXPRESSION;

EARLY GROWTH RESPONSE FACTOR 2; MYELIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR SOX2; DEAD BOX PROTEIN; DGCR8 PROTEIN, MOUSE; DICER1 PROTEIN, MOUSE; MICRORNA; RIBONUCLEASE III; RNA BINDING PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DGCR8 GENE; EGR2 GENE; GENE; GENE EXPRESSION; GENE FUNCTION; MACROPHAGE; MOUSE; MYELINATION; NERVE CELL DIFFERENTIATION; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SCHWANN CELL; SHH GENE; SOX2 GENE; ANIMAL; AXON; CELL DIFFERENTIATION; CROSS BREEDING; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; KNOCKOUT MOUSE; METABOLISM; MYELIN SHEATH; PHENOTYPE;

ANIMALS; AXONS; CELL DIFFERENTIATION; CROSSES, GENETIC; DEAD-BOX RNA HELICASES; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; MACROPHAGES; MICE; MICE, KNOCKOUT; MICRORNAS; MYELIN SHEATH; PHENOTYPE; RIBONUCLEASE III; RNA-BINDING PROTEINS; SCHWANN CELLS;

EID: 84943327663     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.636407     Document Type: Article

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