-
1
-
-
84879080578
-
Molecular targets for treatment of kidney fibrosis
-
Chuang PY, Menon MC, He JC. Molecular targets for treatment of kidney fibrosis. J Mol Med 2013; 91: 549-59.
-
(2013)
J Mol Med
, vol.91
, pp. 549-559
-
-
Chuang, P.Y.1
Menon, M.C.2
He, J.C.3
-
2
-
-
67649397446
-
Inflammation in chronic kidney disease: Role in the progression of renal and cardiovascular disease
-
Silverstein DM. Inflammation in chronic kidney disease: role in the progression of renal and cardiovascular disease. Pediatr Nephrol 2009; 24: 1445-52.
-
(2009)
Pediatr Nephrol
, vol.24
, pp. 1445-1452
-
-
Silverstein, D.M.1
-
3
-
-
34748859681
-
The intrarenal reninangiotensin system: From physiology to the pathobiology of hypertension and kidney disease
-
Kobori H, Nangaku M, Navar LG, Nishiyama A. The intrarenal reninangiotensin system: from physiology to the pathobiology of hypertension and kidney disease. Pharmacol Rev 2007; 59: 251-87.
-
(2007)
Pharmacol Rev
, vol.59
, pp. 251-287
-
-
Kobori, H.1
Nangaku, M.2
Navar, L.G.3
Nishiyama, A.4
-
4
-
-
33750741932
-
Renin-angiotensin-aldosterone system and progression of renal disease
-
Ruster C, Wolf G. Renin-angiotensin-aldosterone system and progression of renal disease. J Am Soc Nephrol 2006; 17: 2985-91.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 2985-2991
-
-
Ruster, C.1
Wolf, G.2
-
5
-
-
70349768250
-
Intrarenal angiotensin II is associated with inflammation, renal damage, and dysfunction in dahl salt-sensitive hypertension
-
Lin L, Phillips WE, Manning RD. Intrarenal angiotensin II is associated with inflammation, renal damage, and dysfunction in dahl salt-sensitive hypertension. J Am Soc Hypertens 2009; 3: 306-14.
-
(2009)
J Am Soc Hypertens
, vol.3
, pp. 306-314
-
-
Lin, L.1
Phillips, W.E.2
Manning, R.D.3
-
6
-
-
84896034350
-
Integrin-linked kinase plays a key role in the regulation of angiotensin II-induced renal inflammation
-
Alique M, Civantos E, Sanchez Lopez E, Lavoz C, Rayego Mateos S, Rodrigues Díez R, et al. Integrin-linked kinase plays a key role in the regulation of angiotensin II-induced renal inflammation. Clin Sci 2014; 127: 19-31.
-
(2014)
Clin Sci
, vol.127
, pp. 19-31
-
-
Alique, M.1
Civantos, E.2
Sanchez Lopez, E.3
Lavoz, C.4
Rayego Mateos, S.5
Rodrigues Díez, R.6
-
7
-
-
84901701308
-
Modulation of angiotensin II-induced inflammatory cytokines by the Epac1-Rap1ANHE3 pathway: Implications in renal tubular pathobiology
-
Xie P, Joladarashi D, Dudeja P, Sun L, Kanwar YS. Modulation of angiotensin II-induced inflammatory cytokines by the Epac1-Rap1ANHE3 pathway: implications in renal tubular pathobiology. Am J Physiol Renal Physiol 2014; 306: F1260-74.
-
(2014)
Am J Physiol Renal Physiol
, vol.306
, pp. F1260-F1274
-
-
Xie, P.1
Joladarashi, D.2
Dudeja, P.3
Sun, L.4
Kanwar, Y.S.5
-
8
-
-
84856857478
-
ER stress activates the NLRP3 inflammasome via an UPR-independent pathway
-
Menu P, Mayor A, Zhou R, Tardivel A, Ichijo H, Mori K, et al. ER stress activates the NLRP3 inflammasome via an UPR-independent pathway. Cell Death Dis 2012; 3: e261.
-
(2012)
Cell Death Dis
, vol.3
, pp. e261
-
-
Menu, P.1
Mayor, A.2
Zhou, R.3
Tardivel, A.4
Ichijo, H.5
Mori, K.6
-
9
-
-
79951578449
-
Inflammasomes: Current understanding and open questions
-
Bauernfeind F, Ablasser A, Bartok E, Kim S, Schmid-Burgk J, Cavlar T, et al. Inflammasomes: current understanding and open questions. Cell Mol Life Sci 2011; 68: 765-83.
-
(2011)
Cell Mol Life Sci
, vol.68
, pp. 765-783
-
-
Bauernfeind, F.1
Ablasser, A.2
Bartok, E.3
Kim, S.4
Schmid-Burgk, J.5
Cavlar, T.6
-
10
-
-
77957887259
-
The NLRP3 inflammasome promotes renal inflammation and contributes to CKD
-
Vilaysane A, Chun J, Seamone ME, Wang W, Chin R, Hirota S, et al. The NLRP3 inflammasome promotes renal inflammation and contributes to CKD. J Am Soc Nephrol 2010; 21: 1732-44.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1732-1744
-
-
Vilaysane, A.1
Chun, J.2
Seamone, M.E.3
Wang, W.4
Chin, R.5
Hirota, S.6
-
11
-
-
77950362382
-
The inflammasomes
-
Schroder K, Tschopp J. The Inflammasomes. Cell 2010; 140: 821-32.
-
(2010)
Cell
, vol.140
, pp. 821-832
-
-
Schroder, K.1
Tschopp, J.2
-
12
-
-
84927173104
-
Enalapril inhibits tubulointerstitial inflammation and NLRP3 inflammasome expression in BSA-overload nephropathy of rats
-
Ding LH, Liu D, Xu M, Liu H, Wu M, Tang RN, et al. Enalapril inhibits tubulointerstitial inflammation and NLRP3 inflammasome expression in BSA-overload nephropathy of rats. Acta Pharmacol Sin 2014; 35: 1293-301.
-
(2014)
Acta Pharmacol Sin
, vol.35
, pp. 1293-1301
-
-
Ding, L.H.1
Liu, D.2
Xu, M.3
Liu, H.4
Wu, M.5
Tang, R.N.6
-
13
-
-
30344442801
-
Angiotensin II: A key factor in the inflammatory and fibrotic response in kidney diseases
-
Ruiz-Ortega M, Ruperez M, Esteban V, Rodriguez-Vita J, Sanchez-Lopez E, Carvajal G, et al. Angiotensin II: a key factor in the inflammatory and fibrotic response in kidney diseases. Nephrol Dial Transpl 2005; 21: 16-20.
-
(2005)
Nephrol Dial Transpl
, vol.21
, pp. 16-20
-
-
Ruiz-Ortega, M.1
Ruperez, M.2
Esteban, V.3
Rodriguez-Vita, J.4
Sanchez-Lopez, E.5
Carvajal, G.6
-
14
-
-
0031858761
-
Angiotensin II participates in mononuclear cell recruitment in experimental immune complex nephritis through nuclear factor-kappa B activation and monocyte chemoattractant protein-1 synthesis
-
Ruiz-Ortega M, Bustos C, Hernandez-Presa MA, Lorenzo O, Plaza JJ, Egido J. Angiotensin II participates in mononuclear cell recruitment in experimental immune complex nephritis through nuclear factor-kappa B activation and monocyte chemoattractant protein-1 synthesis. J Immunol 1998; 161: 430-9.
-
(1998)
J Immunol
, vol.161
, pp. 430-439
-
-
Ruiz-Ortega, M.1
Bustos, C.2
Hernandez-Presa, M.A.3
Lorenzo, O.4
Plaza, J.J.5
Egido, J.6
-
15
-
-
84907280003
-
Regression of glomerular and tubulointerstitial injuries by dietary salt reduction with combination therapy of angiotensin II receptor blocker and calcium channel blocker in dahl salt-sensitive rats
-
Rafiq K, Nishiyama A, Konishi Y, Morikawa T, Kitabayashi C, Kohno M, et al. Regression of glomerular and tubulointerstitial injuries by dietary salt reduction with combination therapy of angiotensin II receptor blocker and calcium channel blocker in dahl salt-sensitive rats. PLoS One 2014; 9: e107853.
-
(2014)
PLoS One
, vol.9
-
-
Rafiq, K.1
Nishiyama, A.2
Konishi, Y.3
Morikawa, T.4
Kitabayashi, C.5
Kohno, M.6
-
16
-
-
0035022842
-
Proinflammatory actions of angiotensins
-
Ruiz-Ortega M, Lorenzo O, Suzuki Y, Rupérez M, Egido J. Proinflammatory actions of angiotensins. Curr Opin Nephrol Hypertens 2001; 10: 321-9.
-
(2001)
Curr Opin Nephrol Hypertens
, vol.10
, pp. 321-329
-
-
Ruiz-Ortega, M.1
Lorenzo, O.2
Suzuki, Y.3
Rupérez, M.4
Egido, J.5
-
17
-
-
84871901528
-
Disruption of Smad7 promotes ANG II-mediated renal inflammation and fibrosis via Sp1-TGF-β/Smad3-NFκB-dependent mechanisms in mice
-
Liu G, Li Y, Huang XR, Wei L, Chen H, Shi Y, et al. Disruption of Smad7 promotes ANG II-mediated renal inflammation and fibrosis via Sp1-TGF-β/Smad3-NFκB-dependent mechanisms in mice. PLoS One 2013; 8: e53573.
-
(2013)
PLoS One
, vol.8
-
-
Liu, G.1
Li, Y.2
Huang, X.R.3
Wei, L.4
Chen, H.5
Shi, Y.6
-
18
-
-
84884194246
-
Angiotensin II-induced production of mitochondrial reactive oxygen species: Potential mechanisms and relevance for cardiovascular disease
-
Dikalov SI, Nazarewicz RR. Angiotensin II-induced production of mitochondrial reactive oxygen species: potential mechanisms and relevance for cardiovascular disease. Antioxid Redox Signal 2013; 19: 1085-94.
-
(2013)
Antioxid Redox Signal
, vol.19
, pp. 1085-1094
-
-
Dikalov, S.I.1
Nazarewicz, R.R.2
-
19
-
-
84892754061
-
Canonical and non-canonical effects of the NLRP3 inflammasome in kidney inflammation and fibrosis
-
Lorenz G, Darisipudi MN, Anders HJ. Canonical and non-canonical effects of the NLRP3 inflammasome in kidney inflammation and fibrosis. Nephrol Dial Transpl 2014; 29: 41-8.
-
(2014)
Nephrol Dial Transpl
, vol.29
, pp. 41-48
-
-
Lorenz, G.1
Darisipudi, M.N.2
Anders, H.J.3
-
20
-
-
79957773993
-
The inflammasomes in kidney disease
-
Anders HJ, Muruve DA. The inflammasomes in kidney disease. J Am Soc Nephrol 2011; 22: 1007-18.
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 1007-1018
-
-
Anders, H.J.1
Muruve, D.A.2
-
21
-
-
84868618082
-
Uromodulin triggers IL-1-dependent innate immunity via the NLRP3 inflammasome
-
Darisipudi MN, Thomasova D, Mulay SR, Brech D, Noessner E, Liapis H, et al. Uromodulin triggers IL-1-dependent innate immunity via the NLRP3 inflammasome. J Am Soc Nephrol 2012; 23: 1783-9.
-
(2012)
J Am Soc Nephrol
, vol.23
, pp. 1783-1789
-
-
Darisipudi, M.N.1
Thomasova, D.2
Mulay, S.R.3
Brech, D.4
Noessner, E.5
Liapis, H.6
-
22
-
-
84873827527
-
Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1β secretion
-
Mulay SR, Kulkarni OP, Rupanagudi KV, Migliorini A, Darisipudi MN, Vilaysane A, et al. Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1β secretion. J Clin Invest 2013; 123: 236-46.
-
(2013)
J Clin Invest
, vol.123
, pp. 236-246
-
-
Mulay, S.R.1
Kulkarni, O.P.2
Rupanagudi, K.V.3
Migliorini, A.4
Darisipudi, M.N.5
Vilaysane, A.6
-
23
-
-
84908222221
-
Endoplasmic reticulum stress is sufficient for the induction of IL-1beta production via activation of the NF-kappaB and inflammasome pathways
-
Kim S, Joe Y, Jeong SO, Zheng M, Back SH, Park SW, et al. Endoplasmic reticulum stress is sufficient for the induction of IL-1beta production via activation of the NF-kappaB and inflammasome pathways. Innate Immun 2014; 20: 799-815.
-
(2014)
Innate Immun
, vol.20
, pp. 799-815
-
-
Kim, S.1
Joe, Y.2
Jeong, S.O.3
Zheng, M.4
Back, S.H.5
Park, S.W.6
-
24
-
-
84864693470
-
Thioredoxin-interacting protein mediates ER stress-induced beta cell death through initiation of the inflammasome
-
Oslowski CM, Hara T, O'Sullivan-Murphy B, Kanekura K, Lu S, Hara M, et al. Thioredoxin-interacting protein mediates ER stress-induced beta cell death through initiation of the inflammasome. Cell Metab 2012; 16: 265-73.
-
(2012)
Cell Metab
, vol.16
, pp. 265-273
-
-
Oslowski, C.M.1
Hara, T.2
O'Sullivan-Murphy, B.3
Kanekura, K.4
Lu, S.5
Hara, M.6
-
25
-
-
84900556997
-
Reduction of endoplasmic reticulum stress by 4-phenylbutyric acid prevents the development of hypoxia-induced pulmonary arterial hypertension
-
Koyama M, Furuhashi M, Ishimura S, Mita T, Fuseya T, Okazaki Y, et al. Reduction of endoplasmic reticulum stress by 4-phenylbutyric acid prevents the development of hypoxia-induced pulmonary arterial hypertension. Am J Physiol Heart Circ Physiol 2014; 306: H1314-23.
-
(2014)
Am J Physiol Heart Circ Physiol
, vol.306
, pp. H1314-H1323
-
-
Koyama, M.1
Furuhashi, M.2
Ishimura, S.3
Mita, T.4
Fuseya, T.5
Okazaki, Y.6
-
26
-
-
64849097016
-
Albumin caused the increasing production of angiotensin II due to the dysregulation of ACE/ACE2 expression in HK2 cells
-
Liu B, Gao J, Li Q, Xu L. Albumin caused the increasing production of angiotensin II due to the dysregulation of ACE/ACE2 expression in HK2 cells. Clin Chim Acta 2009; 403: 23-30.
-
(2009)
Clin Chim Acta
, vol.403
, pp. 23-30
-
-
Liu, B.1
Gao, J.2
Li, Q.3
Xu, L.4
-
27
-
-
84882621088
-
Involvement of endoplasmic reticulum stress in albuminuria induced inflammasome activation in renal proximal tubular cells
-
Fang L, Xie D, Wu X, Cao H, Su W, Yang J. Involvement of endoplasmic reticulum stress in albuminuria induced inflammasome activation in renal proximal tubular cells. PLoS One 2013; 8: e72344.
-
(2013)
PLoS One
, vol.8
-
-
Fang, L.1
Xie, D.2
Wu, X.3
Cao, H.4
Su, W.5
Yang, J.6
-
28
-
-
78650659200
-
An inflammasome-independent role for epithelial-expressed Nlrp3 in renal ischemia-reperfusion injury
-
Shigeoka AA, Mueller JL, Kambo A, Mathison JC, King AJ, Hall WF, et al. An inflammasome-independent role for epithelial-expressed Nlrp3 in renal ischemia-reperfusion injury. J Immunol 2010; 185: 6277-85.
-
(2010)
J Immunol
, vol.185
, pp. 6277-6285
-
-
Shigeoka, A.A.1
Mueller, J.L.2
Kambo, A.3
Mathison, J.C.4
King, A.J.5
Hall, W.F.6
|