Liposomes Combined an Integrin αvβ3-Specific Vector with pH-Responsible Cell-Penetrating Property for Highly Effective Antiglioma Therapy through the Blood-Brain Barrier

ACS Applied Materials and Interfaces

Volumn 7, Issue 38, 2015, Pages 21442-21454

  Shi, Kairong ^a   Long, Yang ^a   Xu, Chaoqun ^b   Wang, Yang ^a   Qiu, Yue ^a   Yu, Qianwen ^a   Liu, Yayuan ^a   Zhang, Qianyu ^a   Gao, Huile ^a   Zhang, Zhirong ^a   He, Qin ^a  

^a SICHUAN UNIVERSITY   (China)

^b Sichuan Academy of Chinese Medicine Sciences   (China)

Author keywords

BBB penetrating; cancer stem cells; glioma targeting; TR peptide; VM channels

Indexed keywords

BLOOD; CONTROLLED DRUG DELIVERY; CYTOLOGY; DISEASES; LIPOSOMES; PEPTIDES; STEM CELLS; SURFACE PLASMON RESONANCE; TARGETED DRUG DELIVERY;

BBB PENETRATING; BIOLOGICAL BARRIER; BLOOD-BRAIN BARRIER; CANCER STEM CELLS; GLIOMA TARGETING; SYSTEMIC CIRCULATION; THERAPEUTIC EFFICACY; VM CHANNELS;

TUMORS;

ANTINEOPLASTIC AGENT; LIPOSOME; PACLITAXEL; PEPTIDE; VITRONECTIN RECEPTOR;

ANIMAL; BAGG ALBINO MOUSE; BLOOD BRAIN BARRIER; BRAIN TUMOR; CANCER STEM CELL; CELL DEATH; CELL LINE; CELL SURVIVAL; CHEMISTRY; DIAGNOSTIC IMAGING; DRUG EFFECTS; ENDOCYTOSIS; EPITHELIUM; FEMALE; GLIOMA; IMPEDANCE; METABOLISM; MULTICELLULAR SPHEROID; PARTICLE SIZE; PATHOLOGY; PH; PROTON NUCLEAR MAGNETIC RESONANCE; STATIC ELECTRICITY; SURFACE PLASMON RESONANCE; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; ANTINEOPLASTIC AGENTS; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; BRAIN NEOPLASMS; CELL DEATH; CELL LINE; CELL SURVIVAL; DIAGNOSTIC IMAGING; ELECTRIC IMPEDANCE; ENDOCYTOSIS; EPITHELIUM; FEMALE; GLIOMA; HYDROGEN-ION CONCENTRATION; INTEGRIN ALPHAVBETA3; LIPOSOMES; MICE, INBRED BALB C; NEOPLASTIC STEM CELLS; PACLITAXEL; PARTICLE SIZE; PEPTIDES; PROTON MAGNETIC RESONANCE SPECTROSCOPY; SPHEROIDS, CELLULAR; STATIC ELECTRICITY; SURFACE PLASMON RESONANCE;

EID: 84942889879     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/acsami.5b06429     Document Type: Article

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