-
1
-
-
84873835755
-
Exercise intolerance in chronic heart failure
-
Okita K, Kinugawa S, Tsutsui H. Exercise intolerance in chronic heart failure. Circ J. 2013;77:293-300.
-
(2013)
Circ J
, vol.77
, pp. 293-300
-
-
Okita, K.1
Kinugawa, S.2
Tsutsui, H.3
-
2
-
-
0029976721
-
Heart failure in rats causes changes in skeletal muscle morphology and gene expression that are not explained by reduced activity
-
Simonini A, Long CS, Dudley GA, Yue P, McElhinny J, Massie BM. Heart failure in rats causes changes in skeletal muscle morphology and gene expression that are not explained by reduced activity. Circ Res. 1996;79:128-136.
-
(1996)
Circ Res
, vol.79
, pp. 128-136
-
-
Simonini, A.1
Long, C.S.2
Dudley, G.A.3
Yue, P.4
McElhinny, J.5
Massie, B.M.6
-
3
-
-
77955496945
-
Making the case for skeletal myopathy as the major limitation of exercise capacity in heart failure
-
Middlekauff HR. Making the case for skeletal myopathy as the major limitation of exercise capacity in heart failure. Circ Heart Fail. 2010;3:537-546. doi: 10.1161/CIRCHEARTFAILURE.109.903773.
-
(2011)
Circ Heart Fail
, vol.3
, pp. 537-546
-
-
Middlekauff, H.R.1
-
5
-
-
0025164904
-
Skeletal muscle biochemistry and histology in ambulatory patients with long-term heart failure
-
Sullivan MJ, Green HJ, Cobb FR. Skeletal muscle biochemistry and histology in ambulatory patients with long-term heart failure. Circulation. 1990;81:518-527.
-
(1990)
Circulation
, vol.81
, pp. 518-527
-
-
Sullivan, M.J.1
Green, H.J.2
Cobb, F.R.3
-
6
-
-
84872899284
-
FOXOs: Signalling integrators for homeostasis maintenance
-
Eijkelenboom A, Burgering BM. FOXOs: signalling integrators for homeostasis maintenance. Nat Rev Mol Cell Biol. 2013;14:83-97. doi: 10.1038/nrm3507.
-
(2013)
Nat Rev Mol Cell Biol
, vol.14
, pp. 83-97
-
-
Eijkelenboom, A.1
Burgering, B.M.2
-
7
-
-
11144356337
-
Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy
-
Sandri M, Sandri C, Gilbert A, Skurk C, Calabria E, Picard A, Walsh K, Schiaffino S, Lecker SH, Goldberg AL. Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell. 2004;117:399-412.
-
(2004)
Cell
, vol.117
, pp. 399-412
-
-
Sandri, M.1
Sandri, C.2
Gilbert, A.3
Skurk, C.4
Calabria, E.5
Picard, A.6
Walsh, K.7
Schiaffino, S.8
Lecker, S.H.9
Goldberg, A.L.10
-
8
-
-
78651321594
-
FoxO1 regulates muscle fiber-type specification and inhibits calcineurin signaling during C2C12 myoblast differentiation
-
Yuan Y, Shi XE, Liu YG, Yang GS. FoxO1 regulates muscle fiber-type specification and inhibits calcineurin signaling during C2C12 myoblast differentiation. Mol Cell Biochem. 2011;348:77-87. doi: 10.1007/s11010-010-0640-1.
-
(2011)
Mol Cell Biochem
, vol.348
, pp. 77-87
-
-
Yuan, Y.1
Shi, X.E.2
Liu, Y.G.3
Yang, G.S.4
-
9
-
-
4544358547
-
Skeletal muscle FOXO1 (FKHR) transgenic mice have less skeletal muscle mass, downregulated Type i (slow twitch/red muscle) fiber genes, and impaired glycemic control
-
Kamei Y, Miura S, Suzuki M, Kai Y, Mizukami J, Taniguchi T, Mochida K, Hata T, Matsuda J, Aburatani H, Nishino I, Ezaki O. Skeletal muscle FOXO1 (FKHR) transgenic mice have less skeletal muscle mass, downregulated Type I (slow twitch/red muscle) fiber genes, and impaired glycemic control. J Biol Chem. 2004;279:41114-41123. doi: 10.1074/jbc. M400674200.
-
(2004)
J Biol Chem
, vol.279
, pp. 41114-41123
-
-
Kamei, Y.1
Miura, S.2
Suzuki, M.3
Kai, Y.4
Mizukami, J.5
Taniguchi, T.6
Mochida, K.7
Hata, T.8
Matsuda, J.9
Aburatani, H.10
Nishino, I.11
Ezaki, O.12
-
10
-
-
79953649622
-
PGC-1α promotes nitric oxide antioxidant defenses and inhibits FOXO signaling against cardiac cachexia in mice
-
Geng T, Li P, Yin X, Yan Z. PGC-1α promotes nitric oxide antioxidant defenses and inhibits FOXO signaling against cardiac cachexia in mice. Am J Pathol. 2011;178:1738-1748. doi: 10.1016/j.ajpath.2011.01.005.
-
(2011)
Am J Pathol
, vol.178
, pp. 1738-1748
-
-
Geng, T.1
Li, P.2
Yin, X.3
Yan, Z.4
-
11
-
-
24744446252
-
Transgenic overexpression of locally acting insulin-like growth factor-1 inhibits ubiquitin-mediated muscle atrophy in chronic left-ventricular dysfunction
-
Schulze PC, Fang J, Kassik KA, Gannon J, Cupesi M, MacGillivray C, Lee RT, Rosenthal N. Transgenic overexpression of locally acting insulin-like growth factor-1 inhibits ubiquitin-mediated muscle atrophy in chronic left-ventricular dysfunction. Circ Res. 2005;97:418-426. doi: 10.1161/01.RES.0000179580.72375.c2.
-
(2005)
Circ Res
, vol.97
, pp. 418-426
-
-
Schulze, P.C.1
Fang, J.2
Kassik, K.A.3
Gannon, J.4
Cupesi, M.5
MacGillivray, C.6
Lee, R.T.7
Rosenthal, N.8
-
12
-
-
33845928762
-
Developmental stage-specific biphasic roles of Wnt/betacatenin signaling in cardiomyogenesis and hematopoiesis
-
Naito AT, Shiojima I, Akazawa H, Hidaka K, Morisaki T, Kikuchi A, Komuro I. Developmental stage-specific biphasic roles of Wnt/betacatenin signaling in cardiomyogenesis and hematopoiesis. Proc Natl Acad Sci U S A. 2006;103:19812-19817. doi: 10.1073/pnas.0605768103.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 19812-19817
-
-
Naito, A.T.1
Shiojima, I.2
Akazawa, H.3
Hidaka, K.4
Morisaki, T.5
Kikuchi, A.6
Komuro, I.7
-
13
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers H. Wnt/beta-catenin signaling in development and disease. Cell. 2006;127:469-480. doi: 10.1016/j.cell.2006.10.018.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
14
-
-
34547924424
-
Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis
-
Brack AS, Conboy MJ, Roy S, Lee M, Kuo CJ, Keller C, Rando TA. Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis. Science. 2007;317:807-810. doi: 10.1126/science.1144090.
-
(2007)
Science
, vol.317
, pp. 807-810
-
-
Brack, A.S.1
Conboy, M.J.2
Roy, S.3
Lee, M.4
Kuo, C.J.5
Keller, C.6
Rando, T.A.7
-
15
-
-
84871846692
-
WNT signalling pathways as therapeutic targets in cancer
-
Anastas JN, Moon RT. WNT signalling pathways as therapeutic targets in cancer. Nat Rev Cancer. 2013;13:11-26. doi: 10.1038/nrc3419.
-
(2013)
Nat Rev Cancer
, vol.13
, pp. 11-26
-
-
Anastas, J.N.1
Moon, R.T.2
-
16
-
-
18844382368
-
Functional interaction between beta-catenin and FOXO in oxidative stress signaling
-
Essers MA, de Vries-Smits LM, Barker N, Polderman PE, Burgering BM, Korswagen HC. Functional interaction between beta-catenin and FOXO in oxidative stress signaling. Science. 2005;308:1181-1184. doi: 10.1126/science.1109083.
-
(2005)
Science
, vol.308
, pp. 1181-1184
-
-
Essers, M.A.1
De Vries-Smits, L.M.2
Barker, N.3
Polderman, P.E.4
Burgering, B.M.5
Korswagen, H.C.6
-
17
-
-
79551707018
-
Wnt signaling regulates hepatic metabolism
-
ra6
-
Liu H, Fergusson MM, Wu JJ, Rovira II, Liu J, Gavrilova O, Lu T, Bao J, Han D, Sack MN, Finkel T. Wnt signaling regulates hepatic metabolism. Sci Signal. 2011;4:ra6. doi: 10.1126/scisignal.2001249.
-
(2011)
Sci Signal
, vol.4
-
-
Liu, H.1
Fergusson, M.M.2
Wu, J.J.3
Rovira, I.I.4
Liu, J.5
Gavrilova, O.6
Lu, T.7
Bao, J.8
Han, D.9
Sack, M.N.10
Finkel, T.11
-
18
-
-
84862013453
-
β-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer
-
Tenbaum SP, Ordopez-Morαn P, Puig I, Chicote I, Arquis O, Landolfi S, Fernαndez Y, Herance JR, Gispert JD, Mendizabal L, Aguilar S, Ramon y Cajal S, Schwartz S Jr, Vivancos A, Espvn E, Rojas S, Baselga J, Tabernero J, Mupoz A, Palmer HG. β-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer. Nat Med. 2012;18:892-901. doi: 10.1038/nm.2772.
-
(2012)
Nat Med
, vol.18
, pp. 892-901
-
-
Tenbaum, S.P.1
Ordez-Morn, P.2
Puig, I.3
Chicote, I.4
Arqus, O.5
Landolfi, S.6
Fernndez, Y.7
Herance, J.R.8
Gispert, J.D.9
Mendizabal, L.10
Aguilar, S.11
Ramn, Y.12
Cajal, S.13
Schwartz, S.14
Vivancos, A.15
Espn, E.16
Rojas, S.17
Baselga, J.18
Tabernero, J.19
Muoz, A.20
Palmer, H.G.21
more..
-
19
-
-
84881231465
-
FOXOs attenuate bone formation by suppressing Wnt signaling
-
Iyer S, Ambrogini E, Bartell SM, Han L, Roberson PK, de Cabo R, Jilka RL, Weinstein RS, OBrien CA, Manolagas SC, Almeida M. FOXOs attenuate bone formation by suppressing Wnt signaling. J Clin Invest. 2013;123:3409-3419. doi: 10.1172/JCI68049.
-
(2013)
J Clin Invest
, vol.123
, pp. 3409-3419
-
-
Iyer, S.1
Ambrogini, E.2
Bartell, S.M.3
Han, L.4
Roberson, P.K.5
De Cabo, R.6
Jilka, R.L.7
Weinstein, R.S.8
OBrien, C.A.9
Manolagas, S.C.10
Almeida, M.11
-
20
-
-
84861994937
-
Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes
-
Naito AT, Sumida T, Nomura S, Liu ML, Higo T, Nakagawa A, Okada K, Sakai T, Hashimoto A, Hara Y, Shimizu I, Zhu W, Toko H, Katada A, Akazawa H, Oka T, Lee JK, Minamino T, Nagai T, Walsh K, Kikuchi A, Matsumoto M, Botto M, Shiojima I, Komuro I. Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes. Cell. 2012;149:1298-1313. doi: 10.1016/j.cell.2012.03.047.
-
(2012)
Cell
, vol.149
, pp. 1298-1313
-
-
Naito, A.T.1
Sumida, T.2
Nomura, S.3
Liu, M.L.4
Higo, T.5
Nakagawa, A.6
Okada, K.7
Sakai, T.8
Hashimoto, A.9
Hara, Y.10
Shimizu, I.11
Zhu, W.12
Toko, H.13
Katada, A.14
Akazawa, H.15
Oka, T.16
Lee, J.K.17
Minamino, T.18
Nagai, T.19
Walsh, K.20
Kikuchi, A.21
Matsumoto, M.22
Botto, M.23
Shiojima, I.24
Komuro, I.25
more..
-
21
-
-
34547610522
-
Knock-in mouse model of dilated cardiomyopathy caused by troponin mutation
-
Du CK, Morimoto S, Nishii K, Minakami R, Ohta M, Tadano N, Lu QW, Wang YY, Zhan DY, Mochizuki M, Kita S, Miwa Y, Takahashi-Yanaga F, Iwamoto T, Ohtsuki I, Sasaguri T. Knock-in mouse model of dilated cardiomyopathy caused by troponin mutation. Circ Res. 2007;101:185-194. doi: 10.1161/CIRCRESAHA.106.146670.
-
(2007)
Circ Res
, vol.101
, pp. 185-194
-
-
Du, C.K.1
Morimoto, S.2
Nishii, K.3
Minakami, R.4
Ohta, M.5
Tadano, N.6
Lu, Q.W.7
Wang, Y.Y.8
Zhan, D.Y.9
Mochizuki, M.10
Kita, S.11
Miwa, Y.12
Takahashi-Yanaga, F.13
Iwamoto, T.14
Ohtsuki, I.15
Sasaguri, T.16
-
22
-
-
84898007067
-
MicroRNA-29 induces cellular senescence in aging muscle through multiple signaling pathways
-
Hu Z, Klein JD, Mitch WE, Zhang L, Martinez I, Wang XH. MicroRNA-29 induces cellular senescence in aging muscle through multiple signaling pathways. Aging (Albany NY). 2014;6:160-175.
-
(2014)
Aging (Albany NY
, vol.6
, pp. 160-175
-
-
Hu, Z.1
Klein, J.D.2
Mitch, W.E.3
Zhang, L.4
Martinez, I.5
Wang, X.H.6
-
23
-
-
0034161544
-
Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR
-
Nakae J, Barr V, Accili D. Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR. EMBO J. 2000;19:989-996. doi: 10.1093/emboj/19.5.989.
-
(2000)
EMBO J
, vol.19
, pp. 989-996
-
-
Nakae, J.1
Barr, V.2
Accili, D.3
-
24
-
-
70350500068
-
FoxO transcription factors promote autophagy in cardiomyocytes
-
Sengupta A, Molkentin JD, Yutzey KE. FoxO transcription factors promote autophagy in cardiomyocytes. J Biol Chem. 2009;284:28319-28331. doi: 10.1074/jbc.M109.024406.
-
(2009)
J Biol Chem
, vol.284
, pp. 28319-28331
-
-
Sengupta, A.1
Molkentin, J.D.2
Yutzey, K.E.3
-
25
-
-
0032480767
-
Skeletal muscle metabolism limits exercise capacity in patients with chronic heart failure
-
Okita K, Yonezawa K, Nishijima H, Hanada A, Ohtsubo M, Kohya T, Murakami T, Kitabatake A. Skeletal muscle metabolism limits exercise capacity in patients with chronic heart failure. Circulation. 1998;98:1886-1891.
-
(1998)
Circulation
, vol.98
, pp. 1886-1891
-
-
Okita, K.1
Yonezawa, K.2
Nishijima, H.3
Hanada, A.4
Ohtsubo, M.5
Kohya, T.6
Murakami, T.7
Kitabatake, A.8
-
26
-
-
76649138257
-
Genetic deletion of myostatin from the heart prevents skeletal muscle atrophy in heart failure
-
Heineke J, Auger-Messier M, Xu J, Sargent M, York A, Welle S, Molkentin JD. Genetic deletion of myostatin from the heart prevents skeletal muscle atrophy in heart failure. Circulation. 2010;121:419-425. doi: 10.1161/CIRCULATIONAHA.109.882068.
-
(2011)
Circulation
, vol.121
, pp. 419-425
-
-
Heineke, J.1
Auger-Messier, M.2
Xu, J.3
Sargent, M.4
York, A.5
Welle, S.6
Molkentin, J.D.7
-
27
-
-
84899450195
-
FoxO transcription factors: Their roles in the maintenance of skeletal muscle homeostasis
-
Sanchez AM, Candau RB, Bernardi H. FoxO transcription factors: their roles in the maintenance of skeletal muscle homeostasis. Cell Mol Life Sci. 2014;71:1657-1671. doi: 10.1007/s00018-013-1513-z.
-
(2014)
Cell Mol Life Sci
, vol.71
, pp. 1657-1671
-
-
Sanchez, A.M.1
Candau, R.B.2
Bernardi, H.3
-
28
-
-
0035477983
-
Reconstitution of the complement function in C1q-deficient (C1qa-/-) mice with wild-type bone marrow cells
-
Petry F, Botto M, Holtappels R, Walport MJ, Loos M. Reconstitution of the complement function in C1q-deficient (C1qa-/-) mice with wild-type bone marrow cells. J Immunol. 2001;167:4033-4037.
-
(2001)
J Immunol
, vol.167
, pp. 4033-4037
-
-
Petry, F.1
Botto, M.2
Holtappels, R.3
Walport, M.J.4
Loos, M.5
-
29
-
-
84862177457
-
Inflammatory cytokines in heart failure: Mediators and markers
-
Gullestad L, Ueland T, Vinge LE, Finsen A, Yndestad A, Aukrust P. Inflammatory cytokines in heart failure: mediators and markers. Cardiology. 2012;122:23-35. doi: 10.1159/000338166.
-
(2012)
Cardiology
, vol.122
, pp. 23-35
-
-
Gullestad, L.1
Ueland, T.2
Vinge, L.E.3
Finsen, A.4
Yndestad, A.5
Aukrust, P.6
-
30
-
-
84901282596
-
Canonical Wnt signaling induces BMP-4 to specify slow myofibrogenesis of fetal myoblasts
-
Kuroda K, Kuang S, Taketo MM, Rudnicki MA. Canonical Wnt signaling induces BMP-4 to specify slow myofibrogenesis of fetal myoblasts. Skelet Muscle. 2013;3:5. doi: 10.1186/2044-5040-3-5.
-
(2013)
Skelet Muscle
, vol.3
, pp. 5
-
-
Kuroda, K.1
Kuang, S.2
Taketo, M.M.3
Rudnicki, M.A.4
-
31
-
-
34848814178
-
Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting beta-catenin from T cell factor-to forkhead box O-mediated transcription
-
Almeida M, Han L, Martin-Millan M, OBrien CA, Manolagas SC. Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting beta-catenin from T cell factor-to forkhead box O-mediated transcription. J Biol Chem. 2007;282:27298-27305. doi: 10.1074/jbc. M702811200.
-
(2007)
J Biol Chem
, vol.282
, pp. 27298-27305
-
-
Almeida, M.1
Han, L.2
Martin-Millan, M.3
OBrien, C.A.4
Manolagas, S.C.5
-
32
-
-
17544379019
-
Direct evidence for increased hydroxyl radicals originating from superoxide in the failing myocardium
-
Ide T, Tsutsui H, Kinugawa S, Suematsu N, Hayashidani S, Ichikawa K, Utsumi H, Machida Y, Egashira K, Takeshita A. Direct evidence for increased hydroxyl radicals originating from superoxide in the failing myocardium. Circ Res. 2000;86:152-157.
-
(2000)
Circ Res
, vol.86
, pp. 152-157
-
-
Ide, T.1
Tsutsui, H.2
Kinugawa, S.3
Suematsu, N.4
Hayashidani, S.5
Ichikawa, K.6
Utsumi, H.7
Machida, Y.8
Egashira, K.9
Takeshita, A.10
-
33
-
-
0035838457
-
Enhanced generation of reactive oxygen species in the limb skeletal muscles from a murine infarct model of heart failure
-
Tsutsui H, Ide T, Hayashidani S, Suematsu N, Shiomi T, Wen J, Nakamura Ki, Ichikawa K, Utsumi H, Takeshita A. Enhanced generation of reactive oxygen species in the limb skeletal muscles from a murine infarct model of heart failure. Circulation. 2001;104:134-136.
-
(2001)
Circulation
, vol.104
, pp. 134-136
-
-
Tsutsui, H.1
Ide, T.2
Hayashidani, S.3
Suematsu, N.4
Shiomi, T.5
Wen, J.6
Ki, N.7
Ichikawa, K.8
Utsumi, H.9
Takeshita, A.10
|