-
1
-
-
64749083599
-
Lung cancer and chronic obstructive pulmonary disease: Needs and opportunities for integrated research
-
Punturieri A, Szabo E, Croxton TL, Shapiro SD, Dubinett SM. Lung cancer and chronic obstructive pulmonary disease: needs and opportunities for integrated research. J Natl Cancer Inst 2009;101:554-559.
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 554-559
-
-
Punturieri, A.1
Szabo, E.2
Croxton, T.L.3
Shapiro, S.D.4
Dubinett, S.M.5
-
3
-
-
84875466646
-
Mechanistic links between COPD and lung cancer
-
Houghton AM. Mechanistic links between COPD and lung cancer. Nat Rev Cancer 2013;13:233-245.
-
(2013)
Nat Rev Cancer
, vol.13
, pp. 233-245
-
-
Houghton, A.M.1
-
4
-
-
0038215542
-
Risk of cancers in COPD patients
-
Nakayama M, Satoh H, Sekizawa K. Risk of cancers in COPD patients. Chest 2003;123:1775-1776.
-
(2003)
Chest
, vol.123
, pp. 1775-1776
-
-
Nakayama, M.1
Satoh, H.2
Sekizawa, K.3
-
5
-
-
4043174733
-
COPD increases the risk of squamous histological subtype in smokers who develop non-small cell lung carcinoma
-
Papi A, Casoni G, Caramori G, et al. COPD increases the risk of squamous histological subtype in smokers who develop non-small cell lung carcinoma. Thorax 2004;59:679-681.
-
(2004)
Thorax
, vol.59
, pp. 679-681
-
-
Papi, A.1
Casoni, G.2
Caramori, G.3
-
6
-
-
4544250024
-
Gene-promoter hypermethylation as a biomarker in lung cancer
-
Belinsky SA. Gene-promoter hypermethylation as a biomarker in lung cancer. Nat Rev Cancer 2004;4:707-717.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 707-717
-
-
Belinsky, S.A.1
-
7
-
-
79954576652
-
EMT and stem cell-like properties associated with miR-205 and miR-200 epigenetic silencing are early manifestations during carcinogen-induced transformation of human lung epithelial cells
-
Tellez CS, Juri DE, Do K, et al. EMT and stem cell-like properties associated with miR-205 and miR-200 epigenetic silencing are early manifestations during carcinogen-induced transformation of human lung epithelial cells. Cancer Res 2011;71:3087-3097.
-
(2011)
Cancer Res
, vol.71
, pp. 3087-3097
-
-
Tellez, C.S.1
Juri, D.E.2
Do, K.3
-
8
-
-
0032578509
-
Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis
-
Belinsky SA, Nikula KJ, Palmisano WA, et al. Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis. Proc Natl Acad Sci U S A 1998;95:11891-11896.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 11891-11896
-
-
Belinsky, S.A.1
Nikula, K.J.2
Palmisano, W.A.3
-
9
-
-
0037089460
-
Aberrant promoter methylation in bronchial epithelium and sputum from current and former smokers
-
Belinsky SA, Palmisano WA, Gilliland FD, et al. Aberrant promoter methylation in bronchial epithelium and sputum from current and former smokers. Cancer Res 2002;62:2370-2377.
-
(2002)
Cancer Res
, vol.62
, pp. 2370-2377
-
-
Belinsky, S.A.1
Palmisano, W.A.2
Gilliland, F.D.3
-
10
-
-
78349241777
-
Wood smoke exposure and gene promoter methylation are associated with increased risk for COPD in smokers
-
Sood A, Petersen H, Blanchette CM, et al. Wood smoke exposure and gene promoter methylation are associated with increased risk for COPD in smokers. Am J Respir Crit Care Med 2010;182:1098-1104.
-
(2011)
Am J Respir Crit Care Med
, vol.182
, pp. 1098-1104
-
-
Sood, A.1
Petersen, H.2
Blanchette, C.M.3
-
11
-
-
77149130202
-
Molecular characterization of chronic obstructive pulmonary disease-related non-small cell lung cancer through aberrant methylation and alterations of EGFR signaling
-
Suzuki M, Wada H, Yoshino M, et al. Molecular characterization of chronic obstructive pulmonary disease-related non-small cell lung cancer through aberrant methylation and alterations of EGFR signaling. Ann Surg Oncol 2010;17:878-888.
-
(2011)
Ann Surg Oncol
, vol.17
, pp. 878-888
-
-
Suzuki, M.1
Wada, H.2
Yoshino, M.3
-
12
-
-
80053304450
-
High density DNA methylation array with single CpG site resolution
-
Bibikova M, Barnes B, Tsan C, et al. High density DNA methylation array with single CpG site resolution. Genomics 2011;98:288-295.
-
(2011)
Genomics
, vol.98
, pp. 288-295
-
-
Bibikova, M.1
Barnes, B.2
Tsan, C.3
-
13
-
-
0035035768
-
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO global initiative for chronic obstructive lung disease (GOLD) workshop summary
-
Pauwels RA, Buist AS, Calverley PM, Jenkins CR, Hurd SS; GOLD Scientific Committee. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO global initiative for chronic obstructive lung disease (GOLD) workshop summary. Am J Respir Crit Care Med 2001;163:1256-1276.
-
(2001)
Am J Respir Crit Care Med
, vol.163
, pp. 1256-1276
-
-
Pauwels, R.A.1
Buist, A.S.2
Calverley, P.M.3
Jenkins, C.R.4
Hurd, S.S.5
Scientific Committee, G.6
-
14
-
-
74049134939
-
MMP12, lung function, and COPD in high-risk populations
-
Hunninghake GM, Cho MH, Tesfaigzi Y, et al. MMP12, lung function, and COPD in high-risk populations. N Engl J Med 2009;361:2599-2608.
-
(2009)
N Engl J Med
, vol.361
, pp. 2599-2608
-
-
Hunninghake, G.M.1
Cho, M.H.2
Tesfaigzi, Y.3
-
15
-
-
84887290753
-
Native American ancestry affects the risk for gene methylation in the lungs of Hispanic smokers from New Mexico
-
Leng S, Liu Y, Thomas CL, et al. Native American ancestry affects the risk for gene methylation in the lungs of Hispanic smokers from New Mexico. Am J Respir Crit Care Med 2013;188:1110-1116.
-
(2013)
Am J Respir Crit Care Med
, vol.188
, pp. 1110-1116
-
-
Leng, S.1
Liu, Y.2
Thomas, C.L.3
-
16
-
-
84863011111
-
Genetic determinants for promoter hypermethylation in the lungs of smokers: A candidate gene-based study
-
Leng S, Stidley CA, Liu Y, et al. Genetic determinants for promoter hypermethylation in the lungs of smokers: a candidate gene-based study. Cancer Res 2012;72:707-715.
-
(2012)
Cancer Res
, vol.72
, pp. 707-715
-
-
Leng, S.1
Stidley, C.A.2
Liu, Y.3
-
17
-
-
42349114374
-
Double-strand break damage and associated DNA repair genes predispose smokers to gene methylation
-
Leng S, Stidley CA, Willink R, et al. Double-strand break damage and associated DNA repair genes predispose smokers to gene methylation. Cancer Res 2008;68:3049-3056.
-
(2008)
Cancer Res
, vol.68
, pp. 3049-3056
-
-
Leng, S.1
Stidley, C.A.2
Willink, R.3
-
18
-
-
55549102330
-
The Pittsburgh lung screening study (PLuSS): Outcomes within 3 years of a first computed tomography scan
-
Wilson DO, Weissfeld JL, Fuhrman CR, et al. The Pittsburgh lung screening study (PLuSS): outcomes within 3 years of a first computed tomography scan. Am J Respir Crit Care Med 2008;178:956-961.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 956-961
-
-
Wilson, D.O.1
Weissfeld, J.L.2
Fuhrman, C.R.3
-
19
-
-
10844284696
-
Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins
-
Ramirez RD, Sheridan S, Girard L, et al. Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins. Cancer Res 2004;64:9027-9034.
-
(2004)
Cancer Res
, vol.64
, pp. 9027-9034
-
-
Ramirez, R.D.1
Sheridan, S.2
Girard, L.3
-
20
-
-
33645521023
-
Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort
-
Belinsky SA, Liechty KC, Gentry FD, et al. Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort. Cancer Res 2006;66:3338-3344.
-
(2006)
Cancer Res
, vol.66
, pp. 3338-3344
-
-
Belinsky, S.A.1
Liechty, K.C.2
Gentry, F.D.3
-
21
-
-
40949141564
-
Promoter methylation of genes in and around the candidate lung cancer susceptibility locus 6q23-25
-
Tessema M, Willink R, Do K, et al. Promoter methylation of genes in and around the candidate lung cancer susceptibility locus 6q23-25. Cancer Res 2008;68:1707-1714.
-
(2008)
Cancer Res
, vol.68
, pp. 1707-1714
-
-
Tessema, M.1
Willink, R.2
Do, K.3
-
22
-
-
67650164499
-
Concomitant promoter methylation of multiple genes in lung adenocarcinomas from current, former and never smokers
-
Tessema M, Yu YY, Stidley CA, et al. Concomitant promoter methylation of multiple genes in lung adenocarcinomas from current, former and never smokers. Carcinogenesis 2009;30:1132-1138.
-
(2009)
Carcinogenesis
, vol.30
, pp. 1132-1138
-
-
Tessema, M.1
Yu, Y.Y.2
Stidley, C.A.3
-
23
-
-
77956929100
-
Re-expression of CXCL14, a common target for epigenetic silencing in lung cancer, induces tumor necrosis
-
Tessema M, Klinge DM, Yingling CM, et al. Re-expression of CXCL14, a common target for epigenetic silencing in lung cancer, induces tumor necrosis. Oncogene 2010;29:5159-5170.
-
(2011)
Oncogene
, vol.29
, pp. 5159-5170
-
-
Tessema, M.1
Klinge, D.M.2
Yingling, C.M.3
-
24
-
-
84905370287
-
Genome-wide unmasking of epigenetically silenced genes in lung adenocarcinoma from smokers and never smokers
-
Tessema M, Yingling CM, Liu Y, et al. Genome-wide unmasking of epigenetically silenced genes in lung adenocarcinoma from smokers and never smokers. Carcinogenesis 2014;35:1248-1257.
-
(2014)
Carcinogenesis
, vol.35
, pp. 1248-1257
-
-
Tessema, M.1
Yingling, C.M.2
Liu, Y.3
-
25
-
-
84859324880
-
SULF2 methylation is prognostic for lung cancer survival and increases sensitivity to topoisomerase-I inhibitors via induction of ISG15
-
Tessema M, Yingling CM, Thomas CL, et al. SULF2 methylation is prognostic for lung cancer survival and increases sensitivity to topoisomerase-I inhibitors via induction of ISG15. Oncogene 2012;31:4107-4116.
-
(2012)
Oncogene
, vol.31
, pp. 4107-4116
-
-
Tessema, M.1
Yingling, C.M.2
Thomas, C.L.3
-
26
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method
-
Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method. Methods 2001;25:402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
27
-
-
79959769526
-
Statistical approaches for the analysis of DNA methylation microarray data
-
Siegmund KD. Statistical approaches for the analysis of DNA methylation microarray data. Hum Genet 2011;129:585-595.
-
(2011)
Hum Genet
, vol.129
, pp. 585-595
-
-
Siegmund, K.D.1
-
28
-
-
0037068393
-
DNA methylation and gene silencing in cancer: Which is the guilty party?
-
Clark SJ, Melki J. DNA methylation and gene silencing in cancer: which is the guilty party? Oncogene 2002;21:5380-5387.
-
(2002)
Oncogene
, vol.21
, pp. 5380-5387
-
-
Clark, S.J.1
Melki, J.2
-
29
-
-
41649093940
-
The methylator phenotype in microsatellite stable colorectal cancers is characterized by a distinct gene expression profile
-
Ferracin M, Gaf R, Miotto E, et al. The methylator phenotype in microsatellite stable colorectal cancers is characterized by a distinct gene expression profile. J Pathol 2008;214:594-602.
-
(2008)
J Pathol
, vol.214
, pp. 594-602
-
-
Ferracin, M.1
Gaf, R.2
Miotto, E.3
-
30
-
-
84655166524
-
Genome-wide analysis of DNA methylation and the gene expression change in lung cancer
-
Kwon YJ, Lee SJ, Koh JS, et al. Genome-wide analysis of DNA methylation and the gene expression change in lung cancer. J Thorac Oncol 2012;7:20-33.
-
(2012)
J Thorac Oncol
, vol.7
, pp. 20-33
-
-
Kwon, Y.J.1
Lee, S.J.2
Koh, J.S.3
-
31
-
-
77953469917
-
Epigenetics as a unifying principle in the aetiology of complex traits and diseases
-
Petronis A. Epigenetics as a unifying principle in the aetiology of complex traits and diseases. Nature 2010;465:721-727.
-
(2011)
Nature
, vol.465
, pp. 721-727
-
-
Petronis, A.1
-
32
-
-
84859312823
-
Differential epigenetic regulation of TOX subfamily high mobility group box genes in lung and breast cancers
-
Tessema M, Yingling CM, Grimes MJ, et al. Differential epigenetic regulation of TOX subfamily high mobility group box genes in lung and breast cancers. PLoS One 2012;7:e34850.
-
(2012)
PLoS One
, vol.7
, pp. e34850
-
-
Tessema, M.1
Yingling, C.M.2
Grimes, M.J.3
-
33
-
-
84876716007
-
The MIA complex is a conserved and novel dynein regulator essential for normal ciliary motility
-
Yamamoto R, Song K, Yanagisawa HA, et al. The MIA complex is a conserved and novel dynein regulator essential for normal ciliary motility. J Cell Biol 2013;201:263-278.
-
(2013)
J Cell Biol
, vol.201
, pp. 263-278
-
-
Yamamoto, R.1
Song, K.2
Yanagisawa, H.A.3
-
34
-
-
44449154833
-
DNA damage, homologydirected repair, and DNA methylation
-
Cuozzo C, Porcellini A, Angrisano T, et al. DNA damage, homologydirected repair, and DNA methylation. PLoS Genet 2007;3:e110.
-
(2007)
PLoS Genet
, vol.3
, pp. e110
-
-
Cuozzo, C.1
Porcellini, A.2
Angrisano, T.3
-
35
-
-
84882456766
-
MAP1B-dependent Rac activation is required for AMPA receptor endocytosis during long-term depression
-
Benoist M, Palenzuela R, Rozas C, et al. MAP1B-dependent Rac activation is required for AMPA receptor endocytosis during long-term depression. EMBO J 2013;32:2287-2299.
-
(2013)
EMBO J
, vol.32
, pp. 2287-2299
-
-
Benoist, M.1
Palenzuela, R.2
Rozas, C.3
-
36
-
-
43949145220
-
DAPK-1 binding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing
-
Harrison B, Kraus M, Burch L, et al. DAPK-1 binding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing. J Biol Chem 2008;283:9999-10014.
-
(2008)
J Biol Chem
, vol.283
, pp. 9999-10014
-
-
Harrison, B.1
Kraus, M.2
Burch, L.3
-
37
-
-
77958072692
-
MAP1B regulates axonal development by modulating Rho-GTPase Rac1 activity
-
Montenegro-Venegas C, Tortosa E, Rosso S, et al. MAP1B regulates axonal development by modulating Rho-GTPase Rac1 activity. Mol Biol Cell 2010;21:3518-3528.
-
(2011)
Mol Biol Cell
, vol.21
, pp. 3518-3528
-
-
Montenegro-Venegas, C.1
Tortosa, E.2
Rosso, S.3
-
38
-
-
0026737638
-
Microtubule-Associated proteins 1A and LC2. Two proteins encoded in one messenger RNA
-
Langkopf A, Hammarback JA, Mller R, Vallee RB, Garner CC. Microtubule-Associated proteins 1A and LC2. Two proteins encoded in one messenger RNA. J Biol Chem 1992;267:16561-16566.
-
(1992)
J Biol Chem
, vol.267
, pp. 16561-16566
-
-
Langkopf, A.1
Hammarback, J.A.2
Mller, R.3
Vallee, R.B.4
Garner, C.C.5
-
39
-
-
48749103221
-
Microtubule-Associated protein 1B light chain (MAP1B-LC1) negatively regulates the activity of tumor suppressor p53 in neuroblastoma cells
-
Lee SY, Kim JW, Jeong MH, et al. Microtubule-Associated protein 1B light chain (MAP1B-LC1) negatively regulates the activity of tumor suppressor p53 in neuroblastoma cells. FEBS Lett 2008;582:2826-2832.
-
(2008)
FEBS Lett
, vol.582
, pp. 2826-2832
-
-
Lee, S.Y.1
Kim, J.W.2
Jeong, M.H.3
-
40
-
-
34249684798
-
Light chain 1 of microtubule-Associated protein 1B can negatively regulate the action of Pes1
-
Lerch-Gaggl AF, Sun K, Duncan SA. Light chain 1 of microtubule-Associated protein 1B can negatively regulate the action of Pes1. J Biol Chem 2007;282:11308-11316.
-
(2007)
J Biol Chem
, vol.282
, pp. 11308-11316
-
-
Lerch-Gaggl, A.F.1
Sun, K.2
Duncan, S.A.3
-
41
-
-
84862572356
-
Defining a gene promoter methylation signature in sputum for lung cancer risk assessment
-
Leng S, Do K, Yingling CM, et al. Defining a gene promoter methylation signature in sputum for lung cancer risk assessment. Clin Cancer Res 2012;18:3387-3395.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 3387-3395
-
-
Leng, S.1
Do, K.2
Yingling, C.M.3
-
42
-
-
84928424453
-
15q12 variants, sputum gene promoter hypermethylation, and lung cancer risk: A GWAS in smokers
-
Leng S, Liu Y, Weissfeld JL, et al. 15q12 variants, sputum gene promoter hypermethylation, and lung cancer risk: a GWAS in smokers. J Natl Cancer Inst 2015;107(5): djv035 doi:10.1093/jnci/djv035.
-
(2015)
J Natl Cancer Inst
, vol.107
, Issue.5
, pp. djv035
-
-
Leng, S.1
Liu, Y.2
Weissfeld, J.L.3
-
43
-
-
84892146454
-
Increased methylation of lung cancer-Associated genes in sputum DNA of former smokers with chronic mucous hypersecretion
-
Bruse S, Petersen H, Weissfeld J, et al. Increased methylation of lung cancer-Associated genes in sputum DNA of former smokers with chronic mucous hypersecretion. Respir Res 2014;15:2.
-
(2014)
Respir Res
, vol.15
, pp. 2
-
-
Bruse, S.1
Petersen, H.2
Weissfeld, J.3
|