-
1
-
-
32244435895
-
Epigenetic regulation of the tumor suppressor gene TCF21 on 6q23-q24 in lung and head and neck cancer
-
Smith LT, Lin M, Brena RM, Lang JC, Schuller DE, et al. (2006) Epigenetic regulation of the tumor suppressor gene TCF21 on 6q23-q24 in lung and head and neck cancer. Proc Natl Acad Sci U S A 103: 982-987.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 982-987
-
-
Smith, L.T.1
Lin, M.2
Brena, R.M.3
Lang, J.C.4
Schuller, D.E.5
-
2
-
-
38549123030
-
Identification of DNA hypermethylation of SOX9 in association with bladder cancer progression using CpG microarrays
-
Aleman A, Adrien L, Lopez-Serra L, Cordon-Cardo C, Esteller M, et al. (2008) Identification of DNA hypermethylation of SOX9 in association with bladder cancer progression using CpG microarrays. Br J Cancer 98: 466-473.
-
(2008)
Br J Cancer
, vol.98
, pp. 466-473
-
-
Aleman, A.1
Adrien, L.2
Lopez-Serra, L.3
Cordon-Cardo, C.4
Esteller, M.5
-
3
-
-
20044362416
-
Epigenome analyses using BAC microarrays identify evolutionary conservation of tissue-specific methylation of SHANK3
-
Ching TT, Maunakea AK, Jun P, Hong C, Zardo G, et al. (2005) Epigenome analyses using BAC microarrays identify evolutionary conservation of tissue-specific methylation of SHANK3. Nat Genet 37: 645-651.
-
(2005)
Nat Genet
, vol.37
, pp. 645-651
-
-
Ching, T.T.1
Maunakea, A.K.2
Jun, P.3
Hong, C.4
Zardo, G.5
-
4
-
-
0033020727
-
Isolation of DNA fragments associated with methylated CpG islands in human adenocarcinomas of the lung using a methylated DNA binding column and denaturing gradient gel electrophoresis
-
Shiraishi M, Chuu YH, Sekiya T, (1999) Isolation of DNA fragments associated with methylated CpG islands in human adenocarcinomas of the lung using a methylated DNA binding column and denaturing gradient gel electrophoresis. Proc Natl Acad Sci U S A 96: 2913-2918.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 2913-2918
-
-
Shiraishi, M.1
Chuu, Y.H.2
Sekiya, T.3
-
5
-
-
0037118586
-
HOX gene clusters are hotspots of de novo methylation in CpG islands of human lung adenocarcinomas
-
Shiraishi M, Sekiguchi A, Oates AJ, Terry MJ, Miyamoto Y, (2002) HOX gene clusters are hotspots of de novo methylation in CpG islands of human lung adenocarcinomas. Oncogene 21: 3659-3662.
-
(2002)
Oncogene
, vol.21
, pp. 3659-3662
-
-
Shiraishi, M.1
Sekiguchi, A.2
Oates, A.J.3
Terry, M.J.4
Miyamoto, Y.5
-
6
-
-
0033563165
-
Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification
-
Toyota M, Ho C, Ahuja N, Jair KW, Li Q, et al. (1999) Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification. Cancer Res 59: 2307-2312.
-
(1999)
Cancer Res
, vol.59
, pp. 2307-2312
-
-
Toyota, M.1
Ho, C.2
Ahuja, N.3
Jair, K.W.4
Li, Q.5
-
7
-
-
0033587747
-
CpG island methylator phenotype in colorectal cancer
-
Toyota M, Ahuja N, Ohe-Toyota M, Herman JG, Baylin SB, et al. (1999) CpG island methylator phenotype in colorectal cancer. Proc Natl Acad Sci U S A 96: 8681-8686.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 8681-8686
-
-
Toyota, M.1
Ahuja, N.2
Ohe-Toyota, M.3
Herman, J.G.4
Baylin, S.B.5
-
8
-
-
0033568534
-
Inactivation of CACNA1G, a T-type calcium channel gene, by aberrant methylation of its 5′ CpG island in human tumors
-
Toyota M, Ho C, Ohe-Toyota M, Baylin SB, Issa JP, (1999) Inactivation of CACNA1G, a T-type calcium channel gene, by aberrant methylation of its 5′ CpG island in human tumors. Cancer Res 59: 4535-4541.
-
(1999)
Cancer Res
, vol.59
, pp. 4535-4541
-
-
Toyota, M.1
Ho, C.2
Ohe-Toyota, M.3
Baylin, S.B.4
Issa, J.P.5
-
9
-
-
0035577825
-
Identification and characterization of differentially methylated CpG islands in pancreatic carcinoma
-
Ueki T, Toyota M, Skinner H, Walter KM, Yeo CJ, et al. (2001) Identification and characterization of differentially methylated CpG islands in pancreatic carcinoma. Cancer Res 61: 8540-8546.
-
(2001)
Cancer Res
, vol.61
, pp. 8540-8546
-
-
Ueki, T.1
Toyota, M.2
Skinner, H.3
Walter, K.M.4
Yeo, C.J.5
-
10
-
-
44349087494
-
Identification of novel tumor markers in prostate, colon and breast cancer by unbiased methylation profiling
-
Chung W, Kwabi-Addo B, Ittmann M, Jelinek J, Shen L, et al. (2008) Identification of novel tumor markers in prostate, colon and breast cancer by unbiased methylation profiling. PLoS One 3: e2079.
-
(2008)
PLoS One
, vol.3
-
-
Chung, W.1
Kwabi-Addo, B.2
Ittmann, M.3
Jelinek, J.4
Shen, L.5
-
11
-
-
0043136717
-
Aberrant promoter methylation of the transcription factor genes PAX5 alpha and beta in human cancers
-
Palmisano WA, Crume KP, Grimes MJ, Winters SA, Toyota M, et al. (2003) Aberrant promoter methylation of the transcription factor genes PAX5 alpha and beta in human cancers. Cancer Res 63: 4620-4625.
-
(2003)
Cancer Res
, vol.63
, pp. 4620-4625
-
-
Palmisano, W.A.1
Crume, K.P.2
Grimes, M.J.3
Winters, S.A.4
Toyota, M.5
-
12
-
-
0035281548
-
HMG1 and 2, and related 'architectural' DNA-binding proteins
-
Thomas JO, Travers AA, (2001) HMG1 and 2, and related 'architectural' DNA-binding proteins. Trends Biochem Sci 26: 167-174.
-
(2001)
Trends Biochem Sci
, vol.26
, pp. 167-174
-
-
Thomas, J.O.1
Travers, A.A.2
-
13
-
-
0037295617
-
Priming the nucleosome: a role for HMGB proteins?
-
Travers AA, (2003) Priming the nucleosome: a role for HMGB proteins? EMBO Rep 4: 131-136.
-
(2003)
EMBO Rep
, vol.4
, pp. 131-136
-
-
Travers, A.A.1
-
14
-
-
2442705192
-
Evidence for involvement of HMGB1 protein in human DNA mismatch repair
-
Yuan F, Gu L, Guo S, Wang C, Li GM, (2004) Evidence for involvement of HMGB1 protein in human DNA mismatch repair. J Biol Chem 279: 20935-20940.
-
(2004)
J Biol Chem
, vol.279
, pp. 20935-20940
-
-
Yuan, F.1
Gu, L.2
Guo, S.3
Wang, C.4
Li, G.M.5
-
15
-
-
0031830815
-
Minor groove-binding architectural proteins: structure, function, and DNA recognition
-
Bewley CA, Gronenborn AM, Clore GM, (1998) Minor groove-binding architectural proteins: structure, function, and DNA recognition. Annu Rev Biophys Biomol Struct 27: 105-131.
-
(1998)
Annu Rev Biophys Biomol Struct
, vol.27
, pp. 105-131
-
-
Bewley, C.A.1
Gronenborn, A.M.2
Clore, G.M.3
-
16
-
-
9444289254
-
TOX defines a conserved subfamily of HMG-box proteins
-
O'Flaherty E, Kaye J, (2003) TOX defines a conserved subfamily of HMG-box proteins. BMC Genomics 4: 13.
-
(2003)
BMC Genomics
, vol.4
, pp. 13
-
-
O'Flaherty, E.1
Kaye, J.2
-
17
-
-
0032900464
-
Diversification pattern of the HMG and SOX family members during evolution
-
Soullier S, Jay P, Poulat F, Vanacker JM, Berta P, et al. (1999) Diversification pattern of the HMG and SOX family members during evolution. J Mol Evol 48: 517-527.
-
(1999)
J Mol Evol
, vol.48
, pp. 517-527
-
-
Soullier, S.1
Jay, P.2
Poulat, F.3
Vanacker, J.M.4
Berta, P.5
-
18
-
-
74549226503
-
HMGB proteins: interactions with DNA and chromatin
-
Stros M, (2010) HMGB proteins: interactions with DNA and chromatin. Biochim Biophys Acta 1799: 101-113.
-
(2010)
Biochim Biophys Acta
, vol.1799
, pp. 101-113
-
-
Stros, M.1
-
19
-
-
0034598746
-
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
-
Alizadeh AA, Eisen MB, Davis RE, Ma C, Lossos IS, et al. (2000) Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403: 503-511.
-
(2000)
Nature
, vol.403
, pp. 503-511
-
-
Alizadeh, A.A.1
Eisen, M.B.2
Davis, R.E.3
Ma, C.4
Lossos, I.S.5
-
20
-
-
0036194770
-
TOX: an HMG box protein implicated in the regulation of thymocyte selection
-
Wilkinson B, Chen JY, Han P, Rufner KM, Goularte OD, et al. (2002) TOX: an HMG box protein implicated in the regulation of thymocyte selection. Nat Immunol 3: 272-280.
-
(2002)
Nat Immunol
, vol.3
, pp. 272-280
-
-
Wilkinson, B.1
Chen, J.Y.2
Han, P.3
Rufner, K.M.4
Goularte, O.D.5
-
21
-
-
2042541388
-
Cloning and characterization of granulosa cell high-mobility group (HMG)-box protein-1, a novel HMG-box transcriptional regulator strongly expressed in rat ovarian granulosa cells
-
Kajitani T, Mizutani T, Yamada K, Yazawa T, Sekiguchi T, et al. (2004) Cloning and characterization of granulosa cell high-mobility group (HMG)-box protein-1, a novel HMG-box transcriptional regulator strongly expressed in rat ovarian granulosa cells. Endocrinology 145: 2307-2318.
-
(2004)
Endocrinology
, vol.145
, pp. 2307-2318
-
-
Kajitani, T.1
Mizutani, T.2
Yamada, K.3
Yazawa, T.4
Sekiguchi, T.5
-
22
-
-
79251571745
-
TOX3 is a neuronal survival factor that induces transcription depending on the presence of CITED1 or phosphorylated CREB in the transcriptionally active complex
-
Dittmer S, Kovacs Z, Yuan SH, Siszler G, Kogl M, et al. (2011) TOX3 is a neuronal survival factor that induces transcription depending on the presence of CITED1 or phosphorylated CREB in the transcriptionally active complex. J Cell Sci 124: 252-260.
-
(2011)
J Cell Sci
, vol.124
, pp. 252-260
-
-
Dittmer, S.1
Kovacs, Z.2
Yuan, S.H.3
Siszler, G.4
Kogl, M.5
-
23
-
-
62449139628
-
TOX3 regulates calcium-dependent transcription in neurons
-
Yuan SH, Qiu Z, Ghosh A, (2009) TOX3 regulates calcium-dependent transcription in neurons. Proc Natl Acad Sci U S A 106: 2909-2914.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 2909-2914
-
-
Yuan, S.H.1
Qiu, Z.2
Ghosh, A.3
-
24
-
-
79951959703
-
TOX4 and its binding partners recognize DNA adducts generated by platinum anticancer drugs
-
du Puch CB, Barbier E, Kraut A, Coute Y, Fuchs J, et al. (2011) TOX4 and its binding partners recognize DNA adducts generated by platinum anticancer drugs. Arch Biochem Biophys 507: 296-303.
-
(2011)
Arch Biochem Biophys
, vol.507
, pp. 296-303
-
-
du Puch, C.B.1
Barbier, E.2
Kraut, A.3
Coute, Y.4
Fuchs, J.5
-
25
-
-
79951658237
-
Prognostic significance of cytoplasmic SOX9 in invasive ductal carcinoma and metastatic breast cancer
-
Chakravarty G, Moroz K, Makridakis NM, Lloyd SA, Galvez SE, et al. (2011) Prognostic significance of cytoplasmic SOX9 in invasive ductal carcinoma and metastatic breast cancer. Exp Biol Med (Maywood) 236: 145-155.
-
(2011)
Exp Biol Med (Maywood)
, vol.236
, pp. 145-155
-
-
Chakravarty, G.1
Moroz, K.2
Makridakis, N.M.3
Lloyd, S.A.4
Galvez, S.E.5
-
26
-
-
0031936644
-
Chromosomal translocations in benign tumors: the HMGI proteins
-
Hess JL, (1998) Chromosomal translocations in benign tumors: the HMGI proteins. Am J Clin Pathol 109: 251-261.
-
(1998)
Am J Clin Pathol
, vol.109
, pp. 251-261
-
-
Hess, J.L.1
-
27
-
-
80051654241
-
SOX2 promotes tumorigenesis and increases the anti-apoptotic property of human prostate cancer cell
-
Jia X, Li X, Xu Y, Zhang S, Mou W, et al. (2011) SOX2 promotes tumorigenesis and increases the anti-apoptotic property of human prostate cancer cell. J Mol Cell Biol 3: 230-238.
-
(2011)
J Mol Cell Biol
, vol.3
, pp. 230-238
-
-
Jia, X.1
Li, X.2
Xu, Y.3
Zhang, S.4
Mou, W.5
-
28
-
-
78449244507
-
SOX17 antagonizes WNT/beta-catenin signaling pathway in hepatocellular carcinoma
-
Jia Y, Yang Y, Liu S, Herman JG, Lu F, et al. (2010) SOX17 antagonizes WNT/beta-catenin signaling pathway in hepatocellular carcinoma. Epigenetics 5: 743-749.
-
(2010)
Epigenetics
, vol.5
, pp. 743-749
-
-
Jia, Y.1
Yang, Y.2
Liu, S.3
Herman, J.G.4
Lu, F.5
-
29
-
-
0033192556
-
HMGI(Y) and HMGI-C dysregulation: a common occurrence in human tumors
-
Tallini G, Dal Cin P, (1999) HMGI(Y) and HMGI-C dysregulation: a common occurrence in human tumors. Adv Anat Pathol 6: 237-246.
-
(1999)
Adv Anat Pathol
, vol.6
, pp. 237-246
-
-
Tallini, G.1
Dal Cin, P.2
-
30
-
-
1242340498
-
High-mobility group A1a protein regulates Ras/ERK signaling in MCF-7 human breast cancer cells
-
Treff NR, Pouchnik D, Dement GA, Britt RL, Reeves R, (2004) High-mobility group A1a protein regulates Ras/ERK signaling in MCF-7 human breast cancer cells. Oncogene 23: 777-785.
-
(2004)
Oncogene
, vol.23
, pp. 777-785
-
-
Treff, N.R.1
Pouchnik, D.2
Dement, G.A.3
Britt, R.L.4
Reeves, R.5
-
31
-
-
42349108108
-
Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer
-
Zhang W, Glockner SC, Guo M, Machida EO, Wang DH, et al. (2008) Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer. Cancer Res 68: 2764-2772.
-
(2008)
Cancer Res
, vol.68
, pp. 2764-2772
-
-
Zhang, W.1
Glockner, S.C.2
Guo, M.3
Machida, E.O.4
Wang, D.H.5
-
32
-
-
0037089460
-
Aberrant promoter methylation in bronchial epithelium and sputum from current and former smokers
-
Belinsky SA, Palmisano WA, Gilliland FD, Crooks LA, Divine KK, et al. (2002) Aberrant promoter methylation in bronchial epithelium and sputum from current and former smokers. Cancer Res 62: 2370-2377.
-
(2002)
Cancer Res
, vol.62
, pp. 2370-2377
-
-
Belinsky, S.A.1
Palmisano, W.A.2
Gilliland, F.D.3
Crooks, L.A.4
Divine, K.K.5
-
33
-
-
10844284696
-
Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins
-
Ramirez RD, Sheridan S, Girard L, Sato M, Kim Y, et al. (2004) Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins. Cancer Res 64: 9027-9034.
-
(2004)
Cancer Res
, vol.64
, pp. 9027-9034
-
-
Ramirez, R.D.1
Sheridan, S.2
Girard, L.3
Sato, M.4
Kim, Y.5
-
34
-
-
40949141564
-
Promoter methylation of genes in and around the candidate lung cancer susceptibility locus 6q23-25
-
Tessema M, Willink R, Do K, Yu YY, Yu W, et al. (2008) Promoter methylation of genes in and around the candidate lung cancer susceptibility locus 6q23-25. Cancer Res 68: 1707-1714.
-
(2008)
Cancer Res
, vol.68
, pp. 1707-1714
-
-
Tessema, M.1
Willink, R.2
Do, K.3
Yu, Y.Y.4
Yu, W.5
-
35
-
-
77956929100
-
Re-expression of CXCL14, a common target for epigenetic silencing in lung cancer, induces tumor necrosis
-
Tessema M, Klinge DM, Yingling CM, Do K, Van Neste L, et al. (2010) Re-expression of CXCL14, a common target for epigenetic silencing in lung cancer, induces tumor necrosis. Oncogene 29: 5159-5170.
-
(2010)
Oncogene
, vol.29
, pp. 5159-5170
-
-
Tessema, M.1
Klinge, D.M.2
Yingling, C.M.3
Do, K.4
Van Neste, L.5
-
36
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
37
-
-
84859324880
-
SULF2 Methylation is Prognostic for Lung Cancer Survival and Increases Sensitivity to Topoisomerase-I inhibitors via Induction of ISG15
-
2011 Dec 12 doi: 101038/onc2011577 [Epub ahead of print]
-
Tessema M, Yingling CM, Thomas CL, Klinge DM, Bernauer AM, et al. (2012) SULF2 Methylation is Prognostic for Lung Cancer Survival and Increases Sensitivity to Topoisomerase-I inhibitors via Induction of ISG15. Oncogene 2011 Dec 12 doi: 101038/onc2011577 [Epub ahead of print].
-
(2012)
Oncogene
-
-
Tessema, M.1
Yingling, C.M.2
Thomas, C.L.3
Klinge, D.M.4
Bernauer, A.M.5
-
38
-
-
0035924324
-
The DNA sequence and comparative analysis of human chromosome 20
-
Deloukas P, Matthews LH, Ashurst J, Burton J, Gilbert JG, et al. (2001) The DNA sequence and comparative analysis of human chromosome 20. Nature 414: 865-871.
-
(2001)
Nature
, vol.414
, pp. 865-871
-
-
Deloukas, P.1
Matthews, L.H.2
Ashurst, J.3
Burton, J.4
Gilbert, J.G.5
-
39
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, et al. (2001) Initial sequencing and analysis of the human genome. Nature 409: 860-921.
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
Lander, E.S.1
Linton, L.M.2
Birren, B.3
Nusbaum, C.4
Zody, M.C.5
-
40
-
-
33751275546
-
Examination of a CpG island methylator phenotype and implications of methylation profiles in solid tumors
-
Marsit CJ, Houseman EA, Christensen BC, Eddy K, Bueno R, et al. (2006) Examination of a CpG island methylator phenotype and implications of methylation profiles in solid tumors. Cancer Res 66: 10621-10629.
-
(2006)
Cancer Res
, vol.66
, pp. 10621-10629
-
-
Marsit, C.J.1
Houseman, E.A.2
Christensen, B.C.3
Eddy, K.4
Bueno, R.5
-
41
-
-
78751512281
-
Combination therapy with vidaza and entinostat suppresses tumor growth and reprograms the epigenome in an orthotopic lung cancer model
-
Belinsky SA, Grimes MJ, Picchi MA, Mitchell HD, Stidley CA, et al. (2011) Combination therapy with vidaza and entinostat suppresses tumor growth and reprograms the epigenome in an orthotopic lung cancer model. Cancer Res 71: 454-462.
-
(2011)
Cancer Res
, vol.71
, pp. 454-462
-
-
Belinsky, S.A.1
Grimes, M.J.2
Picchi, M.A.3
Mitchell, H.D.4
Stidley, C.A.5
-
42
-
-
0037068393
-
DNA methylation and gene silencing in cancer: which is the guilty party?
-
Clark SJ, Melki J, (2002) DNA methylation and gene silencing in cancer: which is the guilty party? Oncogene 21: 5380-5387.
-
(2002)
Oncogene
, vol.21
, pp. 5380-5387
-
-
Clark, S.J.1
Melki, J.2
-
43
-
-
62849100430
-
Aberrant epigenetic silencing is triggered by a transient reduction in gene expression
-
Oyer JA, Chu A, Brar S, Turker MS, (2009) Aberrant epigenetic silencing is triggered by a transient reduction in gene expression. PLoS One 4: e4832.
-
(2009)
PLoS One
, vol.4
-
-
Oyer, J.A.1
Chu, A.2
Brar, S.3
Turker, M.S.4
|