The role of polydextrose in body weight control and glucose regulation

Current Opinion in Clinical Nutrition and Metabolic Care

Volumn 18, Issue 4, 2015, Pages 395-400

  Canfora, Emanuel E ^a   Blaak, Ellen E ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Energy intake; Glucose metabolism; Gut microbiota; Intestinal transit time; Polydextrose; Short chain fatty acids

Indexed keywords

GLUCOSE; POLYDEXTROSE; SHORT CHAIN FATTY ACID; UNCLASSIFIED DRUG; GLUCAN; GLUCOSE BLOOD LEVEL;

ABSORPTION; BODY WEIGHT; CALORIC INTAKE; DIETARY FIBER; ENERGY EXPENDITURE; ENERGY METABOLISM; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; HUMAN; INSULIN SENSITIVITY; INTESTINE FLORA; MACRONUTRIENT; NONHUMAN; REVIEW; ADMINISTRATION AND DOSAGE; DRUG EFFECTS; GASTROINTESTINAL TRACT; GLUCOSE BLOOD LEVEL; HOMEOSTASIS; INSULIN RESISTANCE; METABOLISM; OBESITY; SATIETY;

BLOOD GLUCOSE; BODY WEIGHT; DIETARY FIBER; ENERGY INTAKE; ENERGY METABOLISM; GASTROINTESTINAL TRACT; GLUCANS; GLUCOSE; HOMEOSTASIS; HUMANS; INSULIN RESISTANCE; OBESITY; SATIATION;

EID: 84942768405     PISSN: 13631950     EISSN: 14736519     Source Type: Journal    
DOI: 10.1097/MCO.0000000000000184     Document Type: Review

References (39)

1. Kaczmarczyk MM, Miller MJ, Freund GG. The health benefits of dietary fiber: Beyond the usual suspects of type 2 diabetes mellitus, cardiovascular disease and colon cancer. Metabolism 2012; 61: 1058-1066.
2. Kellow NJ, Coughlan MT, Reid CM. Metabolic benefits of dietary prebiotics in human subjects: A systematic review of randomised controlled trials. Br J Nutr 2014; 111: 1147-1161.
3. Blaak E, Antoine JM, Benton D, et al. Impact of postprandial glycaemia on health and prevention of disease. Obesity Rev 2012; 13: 923-984.
4. Hooda S, Boler BMV, Serao MCR, et al. 454 pyrosequencing reveals a shift in fecal microbiota of healthy adult men consuming polydextrose or soluble corn fiber. J Nutr 2012; 142: 1259-1265.
5. Costabile A, Fava F, RöytiöH, et al. Impact of polydextrose on the faecal microbiota: A double-blind, crossover, placebo-controlled feeding study in healthy human subjects. Br J Nutr 2012; 108: 471-481.
6. den BestenG, van Eunen K, Groen AK, et al. The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism. J Lipid Res 2013; 54: 2325-2340.
7. Konings E, Schoffelen PF, Stegen J, et al. Effect of polydextrose and soluble maize fibre on energy metabolism, metabolic profile and appetite control in overweight men and women. Br J Nutr 2014; 111: 111-1121.
8. Hull S, Re R, Tiihonen K, et al. Consuming polydextrose in a mid-morning snack increases acute satiety measurements and reduces subsequent energy intake at lunch in healthy human subjects. Appetite 2012; 59: 706-712.
9. Ranawana V, Muller A, Henry CJK. Polydextrose: Its impact on short-term food intake and subjective feelings of satiety in males - A randomized controlled cross-over study. Eur J Nutr 2013; 52: 885-893.
10. Astbury NM, Taylor MA, Macdonald IA. Polydextrose results in a dosedependent reduction in ad libitum energy intake at a subsequent test meal. Br J Nutr 2013; 110: 934-942.
11. Olli K, Salli K, Alhoniemi E, et al. Postprandial effects of polydextrose on satiety hormone responses and subjective feelings of appetite in obese participants. Nutr J 2015; 14: 2.
12. Astbury NM, Taylor MA, French SJ, et al. Snacks containing whey protein and polydextrose induce a sustained reduction in daily energy intake over 2 wk under free-living conditions. Am J Clin Nutr 2014; 99: 1131-1140.
13. Vrieze A, Out C, Fuentes S, et al. Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity. J Hepatol 2014; 60: 824-831.
14. Qin J, Li Y, Cai Z, et al. A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature 2012; 490: 55-60.
15. Karlsson FH, Tremaroli V, Nookaew I, et al. Gut metagenome in European women with normal, impaired and diabetic glucose control. Nature 2013; 498: 99-103.
16. Wanders A, Mars M, Borgonjen-Van Den Berg K, et al. Satiety and energy intake after single and repeated exposure to gel-forming dietary fiber: Postingestive effects. Int J Obesity 2014; 38: 794-800.
17. Magro DO, de Oliveira LMR, Bernasconi I, et al. Effect of yogurt containing polydextrose, Lactobacillus acidophilus NCFM and Bifidobacterium lactis HN019: A randomized, double-blind, controlled study in chronic constipation. Nutr J 2014; 13: 75.
18. Timm DA, Thomas W, Boileau TW, et al. Polydextrose and soluble corn fiber increase five-day fecal wet weight in healthy men and women. J Nutr 2013; 143: 473-478.
19. Astrup A. The relevance of increased fat oxidation for body-weight management: Metabolic inflexibility in the predisposition to weight gain. Obesity Rev 2011; 12: 859-865.
20. Shulman GI. Ectopic fat in insulin resistance, dyslipidemia, and cardiometabolic disease. N Engl J Med 2014; 371: 1131-1141.
21. DiamantM, Blaak E, De Vos W. Do nutrient-gut-microbiota interactions play a role in human obesity, insulin resistance and type 2 diabetes? Obes Rev 2011; 12: 272-281.
22. Million M, Maraninchi M, Henry M, et al. Obesity-associated gut microbiota is enriched in Lactobacillus reuteri and depleted in Bifidobacterium animalis and Methanobrevibacter smithii. Int J Obes (Lond) 2012; 36: 817-825.
23. Vester Boler BM, Rossoni Serao MC, Bauer LL, et al. Digestive physiological outcomes related to polydextrose and soluble maize fibre consumption by healthy adult men. Br J Nutr 2011; 106: 1864-1871.
24. Beards E, Tuohy K, Gibson G. A human volunteer study to assess the impact of confectionery sweeteners on the gut microbiota composition. Br J Nutr 2010; 104: 701-708.
25. Mäkeläinen H, Saarinen M, Stowell J, et al. Xylo-oligosaccharides and lactitol promote the growth of Bifidobacterium lactis and Lactobacillus species in pure cultures. Benef Microbes 2010; 1: 139-148.
26. Fava F, Mäkivuokko H, Siljander-Rasi H, et al. Effect of polydextrose on intestinal microbes and immune functions in pigs. Br J Nutr 2007; 98: 123-133.
27. Lin HV, Frassetto A, Kowalik EJ Jr, et al. Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms. PLoS One 2012; 7: E35240.
28. Freeland KR, Wolever T. Acute effects of intravenous and rectal acetate on glucagon-like peptide-1, peptide YY, ghrelin, adiponectin and tumour necrosis factor-alpha. Br J Nutr 2010; 103: 460-466.
29. De Silva A, Bloom SR. Gut hormones and appetite control: A focus on PYY and GLP-1 as therapeutic targets in obesity. Gut Liver 2012; 6: 10-20.
30. Manning S, Batterham RL. The role of gut hormone peptide YY in energy and glucose homeostasis: Twelve years on. Annu Rev Physiol 2014; 76: 585-608.
31. Delzenne N, Blundell J, Brouns F, et al. Gastrointestinal targets of appetite regulation in humans. Obes Rev 2010; 11: 234-250.
32. Frost G, Sleeth ML, Sahuri-Arisoylu M, et al. The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism. Nat Commun 2014; 5: 3611.
33. Gao Z, Yin J, Zhang J, et al. Butyrate improves insulin sensitivity and increases energy expenditure in mice. Diabetes 2009; 58: 1509.
34. den Besten G, Bleeker A, Gerding A, et al. Short-chain fatty acids protect against high-fat diet-induced obesity via a PPARg-dependent switch from lipogenesis to fat oxidation. Diabetes 2015; doi: 10.2337/db14-1213. [Epub ahead of print]
35. De Vadder F, Kovatcheva-Datchary P, Goncalves D, et al. Microbiota-generated metabolites promote metabolic benefits via gut-brain neural circuits. Cell 2014; 156: 84-96.
36. Mithieux G, Gautier-Stein A. Intestinal glucose metabolism revisited. Diabetes Res Clin Practice 2014; 105: 295-301.
37. Tedelind S, Westberg F, Kjerrulf M, et al. Anti-inflammatory properties of the short-chain fatty acids acetate and propionate: A study with relevance to inflammatory bowel disease. World J Gastroenterol 2007; 13: 2826.
38. Liu T, Li J, Liu Y, et al. Short-chain fatty acids suppress lipopolysaccharideinduced production of nitric oxide and proinflammatory cytokines through inhibition of NF-kB pathway in RAW264. 7 cells. Inflammation 2012; 35: 1676-1684.
39. Herfel TM, Jacobi SK, Lin X, et al. Polydextrose enrichment of infant formula demonstrates prebiotic characteristics by altering intestinal microbiota, organic acid concentrations, and cytokine expression in suckling piglets. J Nutr 2011; 141: 2139-2145.