-
1
-
-
80054937214
-
Calcific aortic valve disease: Not simply a degenerative process: A review and agenda for research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group. Executive summary: Calcific aortic valve disease-2011 update
-
Rajamannan NM, Evans FJ, Aikawa E, et al. Calcific aortic valve disease: not simply a degenerative process: a review and agenda for research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group. Executive summary: calcific aortic valve disease-2011 update. Circulation 2011;124:1783-91.
-
(2011)
Circulation
, vol.124
, pp. 1783-1791
-
-
Rajamannan, N.M.1
Evans, F.J.2
Aikawa, E.3
-
2
-
-
37549064021
-
Association between plasma LDL particle size, valvular accumulation of oxidized LDL, and inflammation in patients with aortic stenosis
-
Mohty D, Pibarot P, Despres JP, et al. Association between plasma LDL particle size, valvular accumulation of oxidized LDL, and inflammation in patients with aortic stenosis. Arterioscler Thromb Vasc Biol 2008;28:187-93.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 187-193
-
-
Mohty, D.1
Pibarot, P.2
Despres, J.P.3
-
3
-
-
78650010990
-
Oxidized low-density lipoprotein, angiotensin II and increased waist circumference are associated with valve inflammation in prehypertensive patients with aortic stenosis
-
Côté N, Pibarot P, Pepin A, et al. Oxidized low-density lipoprotein, angiotensin II and increased waist circumference are associated with valve inflammation in prehypertensive patients with aortic stenosis. Int J Cardiol 2009; 145:444-9.
-
(2009)
Int J Cardiol
, vol.145
, pp. 444-449
-
-
Côté, N.1
Pibarot, P.2
Pepin, A.3
-
4
-
-
50249083965
-
Association between circulating oxidised low-density lipoprotein and fibrocalcific remodelling of the aortic valve in aortic stenosis
-
Côté C, Pibarot P, Despres JP, et al. Association between circulating oxidised low-density lipoprotein and fibrocalcific remodelling of the aortic valve in aortic stenosis. Heart 2008;94:1175-80.
-
(2008)
Heart
, vol.94
, pp. 1175-1180
-
-
Côté, C.1
Pibarot, P.2
Despres, J.P.3
-
5
-
-
22544443973
-
Lipoprotein- associated phospholipase A2 as a target of therapy
-
Macphee CH, Nelson JJ, Zalewski A. Lipoprotein- associated phospholipase A2 as a target of therapy. Curr Opin Lipidol 2005;16:442-6.
-
(2005)
Curr Opin Lipidol
, vol.16
, pp. 442-446
-
-
Macphee, C.H.1
Nelson, J.J.2
Zalewski, A.3
-
6
-
-
84893258971
-
Elevated expression of Lp-PLA2 in calcific aortic valve disease: Implication for valve mineralization
-
Mahmut A, Boulanger MC, El Husseini D, et al. Elevated expression of Lp-PLA2 in calcific aortic valve disease: implication for valve mineralization. J Am Coll Cardiol 2014;63:460-9.
-
(2014)
J Am Coll Cardiol
, vol.63
, pp. 460-469
-
-
Mahmut, A.1
Boulanger, M.C.2
El Husseini, D.3
-
7
-
-
84867773641
-
Lipoprotein- associated phospholipase A2 is elevated in patients with severe aortic valve stenosis without clinically overt atherosclerosis
-
Kolasa-Trela R, Fil K, Bazanek M, et al. Lipoprotein- associated phospholipase A2 is elevated in patients with severe aortic valve stenosis without clinically overt atherosclerosis. Clin Chem Lab Med 2012;50:1825-31.
-
(2012)
Clin Chem Lab Med
, vol.50
, pp. 1825-1831
-
-
Kolasa-Trela, R.1
Fil, K.2
Bazanek, M.3
-
8
-
-
0034739287
-
Predictors of outcome in severe, asymptomatic aortic stenosis
-
Rosenhek R, Binder T, Porenta G, et al. Predictors of outcome in severe, asymptomatic aortic stenosis. N Engl J Med 2000;343:611-7.
-
(2000)
N Engl J Med
, vol.343
, pp. 611-617
-
-
Rosenhek, R.1
Binder, T.2
Porenta, G.3
-
9
-
-
69249160933
-
Usefulness of the valvuloarterial impedance to predict adverse outcome in asymptomatic aortic stenosis
-
Hachicha Z, Dumesnil JG, Pibarot P. Usefulness of the valvuloarterial impedance to predict adverse outcome in asymptomatic aortic stenosis. J Am Coll Cardiol 2009;54:1003-11.
-
(2009)
J Am Coll Cardiol
, vol.54
, pp. 1003-1011
-
-
Hachicha, Z.1
Dumesnil, J.G.2
Pibarot, P.3
-
10
-
-
77952343394
-
Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study
-
Suchindran S, Rivedal D, Guyton JR, et al. Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study. PLoS Genet 2010;6:e1000928.
-
(2010)
PLoS Genet
, vol.6
, pp. e1000928
-
-
Suchindran, S.1
Rivedal, D.2
Guyton, J.R.3
-
11
-
-
0033104911
-
Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: Use of a novel inhibitor
-
Macphee CH, Moores KE, Boyd HF, et al. Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: use of a novel inhibitor. Biochem J 1999;338(Pt 2):479-87.
-
(1999)
Biochem J
, vol.338
, pp. 479-487
-
-
Macphee, C.H.1
Moores, K.E.2
Boyd, H.F.3
-
12
-
-
33846548612
-
Lysophosphatidylcholine induces inflammatory activation of human coronary artery smooth muscle cells
-
Aiyar N, Disa J, Ao Z, et al. Lysophosphatidylcholine induces inflammatory activation of human coronary artery smooth muscle cells. Mol Cell Biochem 2007;295:113-20.
-
(2007)
Mol Cell Biochem
, vol.295
, pp. 113-120
-
-
Aiyar, N.1
Disa, J.2
Ao, Z.3
-
13
-
-
33644837920
-
Role of lipoprotein-associated phospholipase A2 in atherosclerosis and its potential as a therapeutic target
-
Macphee CH, Nelson J, Zalewski A. Role of lipoprotein-associated phospholipase A2 in atherosclerosis and its potential as a therapeutic target. Curr Opin Pharmacol 2006;6:154-61.
-
(2006)
Curr Opin Pharmacol
, vol.6
, pp. 154-161
-
-
Macphee, C.H.1
Nelson, J.2
Zalewski, A.3
-
14
-
-
33744455996
-
Emerging medical treatments for aortic stenosis: Statins angiotensin converting enzyme inhibitors or both?
-
Newby DE, Cowell SJ, Boon NA. Emerging medical treatments for aortic stenosis: statins, angiotensin converting enzyme inhibitors, or both? Heart 2006;92:729-34.
-
(2006)
Heart
, vol.92
, pp. 729-734
-
-
Newby, D.E.1
Cowell, S.J.2
Boon, N.A.3
-
15
-
-
50949107980
-
Stage-related effect of statin treatment on the progression of aortic valve sclerosis and stenosis
-
Antonini-Canterin F, Hirsu M, Popescu BA, et al. Stage-related effect of statin treatment on the progression of aortic valve sclerosis and stenosis. Am J Cardiol 2008;102:738-42.
-
(2008)
Am J Cardiol
, vol.102
, pp. 738-742
-
-
Antonini-Canterin, F.1
Hirsu, M.2
Popescu, B.A.3
-
16
-
-
73549103784
-
Mechanisms of aortic valve calcification: The LDL-density-radius theory: A translation from cell signaling to physiology
-
Rajamannan NM. Mechanisms of aortic valve calcification: the LDL-density-radius theory: a translation from cell signaling to physiology. Am J Physiol Heart Circ Physiol 2010;298:H5-15.
-
(2010)
Am J Physiol Heart Circ Physiol
, vol.298
, pp. H5-15
-
-
Rajamannan, N.M.1
-
18
-
-
0029872345
-
Apolipoproteins B (a), and e accumulate in the morphologically early lesion of 'degenerative' valvular aortic stenosis
-
O'Brien KD, Reichenbach DD, Marcovina SM, Kuusisto J, Alpers CE, Otto CM. Apolipoproteins B, (a), and E accumulate in the morphologically early lesion of 'degenerative' valvular aortic stenosis. Arterioscler Thromb Vasc Biol 1996;16:523-32.
-
(1996)
Arterioscler Thromb Vasc Biol
, vol.16
, pp. 523-532
-
-
O'brien, K.D.1
Reichenbach, D.D.2
Marcovina, S.M.3
Kuusisto, J.4
Alpers, C.E.5
Otto, C.M.6
-
19
-
-
0037159283
-
Association of angiotensin-converting enzyme with low-density lipoprotein in aortic valvular lesions and in human plasma
-
O'Brien KD, Shavelle DM, Caulfield MT, et al. Association of angiotensin-converting enzyme with low-density lipoprotein in aortic valvular lesions and in human plasma. Circulation 2002; 106:2224-30.
-
(2002)
Circulation
, vol.106
, pp. 2224-2230
-
-
O'brien, K.D.1
Shavelle, D.M.2
Caulfield, M.T.3
-
20
-
-
84907363577
-
Aortic-valve stenosis- from patients at risk to severe valve obstruction
-
Otto CM, Prendergast B. Aortic-valve stenosis- from patients at risk to severe valve obstruction. N Engl J Med 2014;371:744-56.
-
(2014)
N Engl J Med
, vol.371
, pp. 744-756
-
-
Otto, C.M.1
Prendergast, B.2
-
21
-
-
84880230568
-
Progression of aortic valve stenosis is associated with bone remodelling and secondary hyperparathyroidism in elderly patients-the COFRASA study
-
Hekimian G, Boutten A, Flamant M, et al. Progression of aortic valve stenosis is associated with bone remodelling and secondary hyperparathyroidism in elderly patients-the COFRASA study. Eur Heart J 2013;34:1915-22.
-
(2013)
Eur Heart J
, vol.34
, pp. 1915-1922
-
-
Hekimian, G.1
Boutten, A.2
Flamant, M.3
-
22
-
-
84900423536
-
18F-NaF uptake is a marker of active calcification and disease progression in patients with aortic stenosis
-
Dweck MR, Jenkins WS, Vesey AT, et al. 18F-NaF uptake Is a marker of active calcification and disease progression in patients with aortic stenosis. Circ Cardiovasc Imaging 2014;7:371-8.
-
(2014)
Circ Cardiovasc Imaging
, vol.7
, pp. 371-378
-
-
Dweck, M.R.1
Jenkins, W.S.2
Vesey, A.T.3
-
23
-
-
33646926441
-
Metabolic syndrome negatively influences disease progression and prognosis in aortic stenosis
-
Briand M, Lemieux I, Dumesnil JG, et al. Metabolic syndrome negatively influences disease progression and prognosis in aortic stenosis. J Am Coll Cardiol 2006;47:2229-36.
-
(2006)
J Am Coll Cardiol
, vol.47
, pp. 2229-2236
-
-
Briand, M.1
Lemieux, I.2
Dumesnil, J.G.3
-
24
-
-
84863646913
-
Impact of metabolic syndrome on progression of aortic stenosis: Influence of age and statin therapy
-
Capoulade R, Clavel MA, Dumesnil JG, et al. Impact of metabolic syndrome on progression of aortic stenosis: Influence of age and statin therapy. J Am Coll Cardiol 2012;60:216-23.
-
(2012)
J Am Coll Cardiol
, vol.60
, pp. 216-223
-
-
Capoulade, R.1
Clavel, M.A.2
Dumesnil, J.G.3
-
25
-
-
33646452759
-
Features of the metabolic syndrome and diabetes mellitus as predictors of aortic valve calcification in the Multi- Ethnic Study of Atherosclerosis
-
Katz R, Wong ND, Kronmal R, et al. Features of the metabolic syndrome and diabetes mellitus as predictors of aortic valve calcification in the Multi- Ethnic Study of Atherosclerosis. Circulation 2006; 113:2113-9.
-
(2006)
Circulation
, vol.113
, pp. 2113-2119
-
-
Katz, R.1
Wong, N.D.2
Kronmal, R.3
-
26
-
-
64649096899
-
Relationship of metabolic syndrome to incident aortic valve calcium and aortic valve calcium progression: The Multi-Ethnic Study of Atherosclerosis (MESA)
-
Katz R, Budoff MJ, Takasu J, et al. Relationship of metabolic syndrome to incident aortic valve calcium and aortic valve calcium progression: the Multi-Ethnic Study of Atherosclerosis (MESA). Diabetes 2009;58:813-9.
-
(2009)
Diabetes
, vol.58
, pp. 813-819
-
-
Katz, R.1
Budoff, M.J.2
Takasu, J.3
-
27
-
-
77953478183
-
Agerelated differences in the pathogenesis of calcific aortic stenosis: The potential role of resistin
-
Mohty D, Pibarot P, Despres JP, et al. Agerelated differences in the pathogenesis of calcific aortic stenosis: the potential role of resistin. Int J Cardiol 2010;142:126-32.
-
(2010)
Int J Cardiol
, vol.142
, pp. 126-132
-
-
Mohty, D.1
Pibarot, P.2
Despres, J.P.3
-
28
-
-
79955969057
-
Hypoadiponectinemia is associated with valvular inflammation and faster disease progression in patients with aortic stenosis
-
Mohty D, Pibarot P, Côté N, et al. Hypoadiponectinemia is associated with valvular inflammation and faster disease progression in patients with aortic stenosis. Cardiology 2011;118:140-6.
-
(2011)
Cardiology
, vol.118
, pp. 140-146
-
-
Mohty, D.1
Pibarot, P.2
Côté, N.3
-
29
-
-
0026682450
-
Variations in oxidative susceptibility among six low density lipoprotein subfractions of differing density and particle size
-
Tribble DL, Holl LG, Wood PD, Krauss RM. Variations in oxidative susceptibility among six low density lipoprotein subfractions of differing density and particle size. Atherosclerosis 1992;93: 189-99.
-
(1992)
Atherosclerosis
, vol.93
, pp. 189-199
-
-
Tribble, D.L.1
Holl, L.G.2
Wood, P.D.3
Krauss, R.M.4
-
30
-
-
0035818513
-
Comparison of various electrophoretic characteristics of LDL particles and their relationship to the risk of ischemic heart disease
-
St Pierre AC, Ruel IL, Cantin B, et al. Comparison of various electrophoretic characteristics of LDL particles and their relationship to the risk of ischemic heart disease. Circulation 2001;104:2295-9.
-
(2001)
Circulation
, vol.104
, pp. 2295-2299
-
-
St Pierre, A.C.1
Ruel, I.L.2
Cantin, B.3
-
31
-
-
0032881725
-
The small, dense LDL phenotype and the risk of coronary heart disease: Epidemiology, patho-physiology and therapeutic aspects
-
Lamarche B, Lemieux I, Despres JP. The small, dense LDL phenotype and the risk of coronary heart disease: epidemiology, patho-physiology and therapeutic aspects. Diabetes Metab 1999;25: 199-211.
-
(1999)
Diabetes Metab
, vol.25
, pp. 199-211
-
-
Lamarche, B.1
Lemieux, I.2
Despres, J.P.3
-
32
-
-
84865120887
-
Lipoprotein(a) as a potential causal genetic risk factor of cardiovascular disease: A rationale for increased efforts to understand its pathophysiology and develop targeted therapies
-
Tsimikas S, Hall JL. Lipoprotein(a) as a potential causal genetic risk factor of cardiovascular disease: a rationale for increased efforts to understand its pathophysiology and develop targeted therapies. J Am Coll Cardiol 2012;60:716-21.
-
(2012)
J Am Coll Cardiol
, vol.60
, pp. 716-721
-
-
Tsimikas, S.1
Hall, J.L.2
-
33
-
-
84865308113
-
Mechanisms of lipoprotein( a) pathogenicity: Prothrombotic proatherosclerotic or both?
-
Spence JD, Koschinsky M. Mechanisms of lipoprotein( a) pathogenicity: prothrombotic, proatherosclerotic, or both? Arterioscler Thromb Vasc Biol 2012;32:1550-1.
-
(2012)
Arterioscler Thromb Vasc Biol
, vol.32
, pp. 1550-1551
-
-
Spence, J.D.1
Koschinsky, M.2
-
34
-
-
84893333521
-
Elevated lipoprotein(a) and risk of aortic valve stenosis in the general population
-
Kamstrup PR, Tybjaerg-Hansen A, Nordestgaard BG. Elevated lipoprotein(a) and risk of aortic valve stenosis in the general population. J Am Coll Cardiol 2014;63:470-7.
-
(2014)
J Am Coll Cardiol
, vol.63
, pp. 470-477
-
-
Kamstrup, P.R.1
Tybjaerg-Hansen, A.2
Nordestgaard, B.G.3
-
35
-
-
84873513160
-
Genetic associations with valvular calcification and aortic stenosis
-
Thanassoulis G, Campbell CY, Owens DS, et al. Genetic associations with valvular calcification and aortic stenosis. N Engl J Med 2013;368:503-12.
-
(2013)
N Engl J Med
, vol.368
, pp. 503-512
-
-
Thanassoulis, G.1
Campbell, C.Y.2
Owens, D.S.3
-
36
-
-
84893324002
-
New therapeutic targets for calcific aortic valve stenosis: The lipoprotein(a)-lipoprotein-associated phospholipase A2-oxidized phospholipid axis
-
Hung MY, Witztum JL, Tsimikas S. New therapeutic targets for calcific aortic valve stenosis: the lipoprotein(a)-lipoprotein-associated phospholipase A2-oxidized phospholipid axis. J Am Coll Cardiol 2014;63:478-80.
-
(2014)
J Am Coll Cardiol
, vol.63
, pp. 478-480
-
-
Hung, M.Y.1
Witztum, J.L.2
Tsimikas, S.3
-
37
-
-
20344364674
-
A randomized trial of intensive lipid-lowering therapy in calcific aortic stenosis
-
Cowell SJ, Newby DE, Prescott RJ, et al. A randomized trial of intensive lipid-lowering therapy in calcific aortic stenosis. N Engl J Med 2005;352:2389-97.
-
(2005)
N Engl J Med
, vol.352
, pp. 2389-2397
-
-
Cowell, S.J.1
Newby, D.E.2
Prescott, R.J.3
-
38
-
-
52649120889
-
Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis
-
Rossebo AB, Pedersen TR, Boman K, et al. Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis. N Engl J Med 2008; 359:1343-56.
-
(2008)
N Engl J Med
, vol.359
, pp. 1343-1356
-
-
Rossebo, A.B.1
Pedersen, T.R.2
Boman, K.3
-
39
-
-
74949091630
-
Effect of lipid lowering with rosuvastatin on progression of aortic stenosis. Results of the aortic stenosis progression observation: Measuring effects of rosuvastatin (ASTRONOMER) trial
-
Chan KL, Teo K, Dumesnil JG, Ni A, Tam J. Effect of lipid lowering with rosuvastatin on progression of aortic stenosis. Results of the aortic stenosis progression observation: measuring effects of rosuvastatin (ASTRONOMER) trial. Circulation 2010;121:306-14.
-
(2010)
Circulation
, vol.121
, pp. 306-314
-
-
Chan, K.L.1
Teo, K.2
Dumesnil, J.G.3
Ni, A.4
Tam, J.5
-
40
-
-
78149452615
-
Impact of baseline severity of aortic valve stenosis on effect of intensive lipid lowering therapy (from the SEAS study)
-
Gerdts E, Rossebo AB, Pedersen TR, et al. Impact of baseline severity of aortic valve stenosis on effect of intensive lipid lowering therapy (from the SEAS study). Am J Cardiol 2010;106:1634-9.
-
(2010)
Am J Cardiol
, vol.106
, pp. 1634-1639
-
-
Gerdts, E.1
Rossebo, A.B.2
Pedersen, T.R.3
-
41
-
-
77953215987
-
Increased biglycan in aortic valve stenosis leads to the overexpression of phospholipid transfer protein via toll-like receptor 2
-
Derbali H, Bossé Y, Côté N, et al. Increased biglycan in aortic valve stenosis leads to the overexpression of phospholipid transfer protein via toll-like receptor 2. Am J Pathol 2010;176: 2638-45.
-
(2010)
Am J Pathol
, vol.176
, pp. 2638-2645
-
-
Derbali, H.1
Bossé, Y.2
Côté, N.3
-
42
-
-
40149109169
-
Visceral obesity and the heart
-
Mathieu P, Pibarot P, Larose E, Poirier P, Marette A, Despres JP. Visceral obesity and the heart. Int J Biochem Cell Biol 2008;40:821-36.
-
(2008)
Int J Biochem Cell Biol
, vol.40
, pp. 821-836
-
-
Mathieu, P.1
Pibarot, P.2
Larose, E.3
Poirier, P.4
Marette, A.5
Despres, J.P.6
-
43
-
-
77949874469
-
Obesity, inflammation, and cardiovascular risk
-
Mathieu P, Lemieux I, Despres JP. Obesity, inflammation, and cardiovascular risk. Clin Pharmacol Ther 2010;87:407-16.
-
(2010)
Clin Pharmacol Ther
, vol.87
, pp. 407-416
-
-
Mathieu, P.1
Lemieux, I.2
Despres, J.P.3
-
44
-
-
58149157445
-
Lipoprotein- associated phospholipase A2 activity, ferritin levels, metabolic syndrome, and 10-year cardiovascular and non-cardiovascular mortality: Results from the Bruneck study
-
Tsimikas S, Willeit J, Knoflach M, et al. Lipoprotein- associated phospholipase A2 activity, ferritin levels, metabolic syndrome, and 10-year cardiovascular and non-cardiovascular mortality: results from the Bruneck study. Eur Heart J 2009; 30:107-15.
-
(2009)
Eur Heart J
, vol.30
, pp. 107-115
-
-
Tsimikas, S.1
Willeit, J.2
Knoflach, M.3
-
45
-
-
84899718423
-
Darapladib for preventing ischemic events in stable coronary heart disease
-
STABILITY Investigators, White HD, Held C, Stewart R, et al. Darapladib for preventing ischemic events in stable coronary heart disease. N Engl J Med 2014;370:1702-11.
-
(2014)
N Engl J Med
, vol.370
, pp. 1702-1711
-
-
STABILITY Investigators1
White, H.D.2
Held, C.3
Stewart, R.4
-
46
-
-
84907007906
-
Effect of darapladib on major coronary events after an acute coronary syndrome: The SOLID-TIMI 52 randomized clinical trial
-
O'Donoghue ML, Braunwald E, White HD, et al. Effect of darapladib on major coronary events after an acute coronary syndrome: the SOLID-TIMI 52 randomized clinical trial. JAMA 2014;312:1006-15.
-
(2014)
JAMA
, vol.312
, pp. 1006-1015
-
-
O'donoghue, M.L.1
Braunwald, E.2
White, H.D.3
|