Elevated expression of lipoprotein-associated phospholipase A2 in calcific aortic valve disease: Implications for valve mineralization

Journal of the American College of Cardiology

Volumn 63, Issue 5, 2014, Pages 460-469

  Mahmut, Ablajan ^a   Boulanger, Marie Chloé ^a   El Husseini, Diala ^a   Fournier, Dominique ^a   Bouchareb, Rihab ^a   Després, Jean Pierre ^a   Pibarot, Philippe ^a   Bossé, Yohan ^a   Mathieu, Patrick ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

apoptosis; calcific aortic valve disease; ectonucleotide pyrophosphatase phosphodiesterase 1; lipoprotein associated phospholipase A2; lysophosphatidylcholine; protein kinase A; valve interstitial cells

Indexed keywords

1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; ALKALINE PHOSPHATASE; AUTOTAXIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; LYSOPHOSPHATIDYLCHOLINE; MESSENGER RNA; OSTEOPONTIN; OXIDIZED LOW DENSITY LIPOPROTEIN; SODIUM PHOSPHATE COTRANSPORTER 1; ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1; PHOSPHODIESTERASE; UNCLASSIFIED DRUG;

ADULT; AGED; AORTA STENOSIS; AORTA VALVE; AORTA VALVE DISEASE; AORTIC VALVE REMODELING; AORTIC VALVE REPAIR; APOPTOSIS; ARTERY CALCIFICATION; ARTICLE; CALCIFIC AORTIC VALVE DISEASE; CONTROLLED STUDY; CORRELATIONAL STUDY; DISEASE ACTIVITY; DISEASE SEVERITY; DOWN REGULATION; ENZYME ACTIVITY; FEMALE; GENE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MINERALIZATION; PLA2G7 GENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SLC20A1 GENE; TISSUE MICROARRAY; TRANSCRIPTOMICS; AORTA VALVE STENOSIS; CALCIFICATION; GENETIC TRANSCRIPTION; IN VITRO STUDY;

ALKALINE PHOSPHATASE; ALP; APOPTOSIS; CALCIFIC AORTIC VALVE DISEASE; CAMP; CAVD; CYCLIC ADENOSINE MONOPHOSPHATE; ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1; ENPP1; INORGANIC PHOSPHATE; INORGANIC PYROPHOSPHATE; LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2; LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 (ENCODED BY PLA2G7 GENE); LP-PLA2; LPC; LYSOPHOSPHATIDYLCHOLINE; OPN; OSTEOPONTIN; OX-LDL; OXIDIZED LOW-DENSITY LIPOPROTEIN; PI; PIT-1; PKA; PPI; PROTEIN KINASE A; SODIUM-DEPENDENT PHOSPHATE COTRANSPORTER 1 (ENCODED BY SLC20A1 GENE); VALVE INTERSTITIAL CELLS; VALVE INTERSTITIAL CELLS; VIC;

1-ALKYL-2-ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; AGED; AORTIC VALVE; CALCINOSIS; ECHOCARDIOGRAPHY, DOPPLER; FEMALE; FOLLOW-UP STUDIES; GENE EXPRESSION REGULATION; HEART DEFECTS, CONGENITAL; HEART VALVE DISEASES; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; PROGNOSIS; RNA, MESSENGER; SEVERITY OF ILLNESS INDEX;

EID: 84893258971     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2013.05.105     Document Type: Article

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