Identification of active site residues of the adeno-associated virus type 2 Rep endonuclease

Journal of Biological Chemistry

Volumn 278, Issue 7, 2003, Pages 4912-4918

  Yoon Robarts, Miran ^a   Linden, R Michael ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CATALYST ACTIVITY; CHROMOSOMES; CRYSTAL STRUCTURE; DNA; ENZYMES; IONS; MUTAGENESIS;

BIOCHEMICAL ACTIVITIES;

VIRUSES;

AMINO ACID; CYSTEINE; ENDONUCLEASE; GLUTAMIC ACID; METAL ION; REP ENDONUCLEASE; RESTRICTION ENDONUCLEASE; UNCLASSIFIED DRUG; VIRUS DNA; ADENOSINE TRIPHOSPHATASE; HELICASE; VIRUS PROTEIN;

ADENO ASSOCIATED VIRUS; ARTICLE; CHEMICAL ANALYSIS; CHROMOSOME 19; CRYSTAL STRUCTURE; DNA BINDING; DNA REPLICATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME STRUCTURE; GENE MAPPING; HUMAN; METAL BINDING; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; TRANSESTERIFICATION; VIRUS GENOME; BINDING SITE; ENZYME SPECIFICITY; ENZYMOLOGY; METABOLISM;

ADENO-ASSOCIATED VIRUS; ADENO-ASSOCIATED VIRUS 2; DNA VIRUSES;

ADENOSINE TRIPHOSPHATASES; BINDING SITES; CATALYTIC DOMAIN; DEPENDOVIRUS; DNA HELICASES; SUBSTRATE SPECIFICITY; VIRAL PROTEINS;

EID: 0038475876     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M209750200     Document Type: Article

References (44)

1. Linden, R. M., and Berns, K. I. (2000) Contrib. Microbiol. 4, 68-84
2. Dutheil, N., Shi, F., Dupressoir, T., and Linden, R. M. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 4862-4866
3. Kotin, R. M., Siniscalco, M., Samulski, R. J., Zhu, X. D., Hunter, L., Laughlin, C. A., McLaughlin, S., Muzyczka, N., Rocchi, M., and Berns, K. I. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 2211-2215
4. Kotin, R. M., Linden, R. M., and Berns, K. I. (1992) EMBO J. 11, 5071-5078
5. Kotin, R. M., Menninger, J. C., Ward, D. C., and Berns, K. I. (1991) Genomics 10, 831-834
6. Linden, R. M., Winocour, E., and Berns, K. I. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 7966-7972
7. Linden, R. M., and Berns, K. I. (1997) Gene Ther. 4, 4-5
8. Linden, R. M., Ward, P., Giraud, C., Winocour, E., and Berns, K. I. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 11288-11294
9. Samulski, R. J., Zhu, X., Xiao, X., Brook, J. D., Housman, D. E., Epstein, N., and Hunter, L. A. (1991) EMBO J. 10, 3941-3950
10. Berns, K. I., and Linden, R. M. (1995) Bioessays 17, 237-245
11. Berns, K. I., Pinkerton, T. C., Thomas, G. F., and Hoggan, M. D. (1975) Virology 68, 556-560
12. Cheung, A. K., Hoggan, M. D., Hauswirth, W. W., and Berns, K. I. (1980) J. Virol. 33, 739-748
13. Kotin, R. M. (1994) Hum. Gene Ther. 5, 793-801
14. Yoon, M., Smith, D. H., Ward, P., Medrano, F. J., Aggarwal, A. K., and Linden, R. M. (2001) J. Virol. 75, 3230-3239
15. Ward, P., and Berns, K. I. (1995) Virology 209, 692-695
16. Smith, D. H., Ward, P., and Linden, R. M. (1999) J. Virol. 73, 2930-2937
17. Berns, K. I. (1996) in Fields Virology (Fields, B. N., Knipe, D. M., and Howley, P. M., eds) Vol. 2, 3rd Ed., pp. 2173-2197, Lippincott-Raven, Philadelphia
18. Cathomen, T., Collete, D., and Weitzman, M. D. (2000) J. Virol. 74, 2372-2382
19. Davis, M. D., Wu, J., and Owens, R. A. (2000) J. Virol. 74, 2936-2942
20. Snyder, R. O., Im, D. S., and Muzyczka, N. (1990) J. Virol. 64, 6204-6213
21. Im, D. S., and Muzyczka, N. (1990) Cell 61, 447-457
22. Smith, R. H., and Kotin, R. M. (2000) J. Virol. 74, 3122-3129
23. Brister, J. R., and Muzyczka, N. (1999) J. Virol. 73, 9325-9336
24. Horer, M., Weger, S., Butz, K., Hoppe-Seyler, F., Geisen, C., and Kleinschmidt J. A. (1995) J. Virol. 69, 5485-5496
25. Hickman, A. B., Ronning, D. R., Kotin, R. M., and Dyda, F. (2002) Mol. Cell 10, 327-337
26. Chiorini, J. A., Kim, F., Yang, L., and Kotin, R. M. (1999) J. Virol. 73, 1309-1319
27. Sarnovsky, R. J., May, E. W. and Craig, N. L. (1996) EMBO J. 15, 6348-6361
28. Allingham, J. S., Pribil, P. A., and Haniford, D. B. (1999) J. Mol. Biol. 289, 1195-1206
29. Fugmann, S. D., Villey, I. J., Ptaszek, L. M., and Schatz, D. G. (2000) Mol. Cell 5, 97-107
30. Landree, M. A. Wibbenmeyer, J. A., and Roth, D. B. (1999) Genes Dev. 13, 3059-3069
31. Pecoraro, V. L., Hermes, J. D., and Cleland, W. W. (1984) Biochemistry 23, 5262-5271
32. Urabe, M., Hasumi, Y., Kume, A., Surosky, R. T., Kurtzman, G. J., Tobita, K., and Ozawa, K. (1999) J. Virol. 73, 2682-2693
33. Zhou, X., Zolotukhin, I., Irn, D. S., and Muzyczka, N. (1999) J. Virol. 73, 1580-1590
34. Im, D. S., and Muzyczka, N. (1992) J. Virol. 66, 1119-1128
35. Smith, R. H., and Kotin, R. M. (1998) J. Virol. 72, 4874-4881
36. Walker, S. L., Wonderling, R. S., and Owens, R. A. (1997) J. Virol. 71, 6996-7004
37. Koonin, E. V., and Ilyina, T. V. (1993) Biosystems 30, 241-268
38. Davis, M. D., Wonderling, R. S., Walker, S. L., and Owens, R. A. (1999) J. Virol. 73, 2084-2093
39. Chiorini, J. A., Afione, S., and Kotin, R. M. (1999) J. Virol. 73, 4293-4298
40. Galburt, E. A., and Stoddard, B. L. (2002) Biochemistry 41, 13851-13860
41. Santagata, S., Aidinis, V., and Spanopoulou, E. (1998) J. Biol. Chem. 273, 16325-16331
42. Allingham, J. S., and Haniford, D. B. (2002) J. Mol. Biol. 319, 53-65
43. Zhu, C. X., Roche, C. J., and Tse-Dinh, Y. C. (1997) J. Biol. Chem. 272, 16206-16210
44. Zhu, C. X., and Tse-Dinh, Y. C. (2000) J. Biol. Chem. 275, 5318-5322