Cisplatin hepatotoxicity mediated by mitochondrial stress

Drug and Chemical Toxicology

Volumn 38, Issue 4, 2015, Pages 452-459

  Waseem, Mohammad ^a   Bhardwaj, Monica ^a   Tabassum, Heena ^a   Raisuddin, Sheikh ^a   Parvez, Suhel ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

Anti cancer drugs; antioxidants; biomarkers; oxidative stress; respiratory chain enzymes

Indexed keywords

CISPLATIN; GLUTATHIONE; MITOCHONDRIAL PROTEIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); UBIQUINOL CYTOCHROME C REDUCTASE; ANTINEOPLASTIC AGENT; BIOLOGICAL MARKER; MULTIENZYME COMPLEX;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTRON TRANSPORT; ENZYME ACTIVITY; IN VITRO STUDY; ISOLATED LIVER; LIPID OXIDATION; LIPID PEROXIDATION; LIVER MITOCHONDRION; LIVER TOXICITY; MALE; MITOCHONDRIAL RESPIRATION; MITOCHONDRIAL STRESS; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PROTEIN DETERMINATION; RAT; RESPIRATORY CHAIN; ANIMAL; DOSE RESPONSE; DRUG EFFECTS; DRUG-INDUCED LIVER INJURY; METABOLISM; PATHOLOGY; WISTAR RAT;

ANIMALS; ANTINEOPLASTIC AGENTS; BIOMARKERS; CISPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG-INDUCED LIVER INJURY; ELECTRON TRANSPORT CHAIN COMPLEX PROTEINS; LIPID PEROXIDATION; MALE; MITOCHONDRIA, LIVER; OXIDATIVE STRESS; RATS; RATS, WISTAR;

EID: 84942593617     PISSN: 01480545     EISSN: 15256014     Source Type: Journal    
DOI: 10.3109/01480545.2014.992437     Document Type: Article

References (53)

1. Aiken CT, Kaake RM, Wang X, Huang L. (2011). Oxidative stress-mediated regulation of proteasome complexes. Mol Cell Proteomics 10: R110.006924
2. Amptoulach S, Tsavaris N. (2011). Neurotoxicity caused by the treatment with platinum analogues. Chemother Res Pract 2011: 843019
3. Barichello T, Savi GD, Simões LR, et al. (2010). Evaluation of mitochondrial respiratory chain in the brain of rats after pneumococcal meningitis. Brain Res Bull 82:302-7
4. Berson A, Cazanave S, Descatoire V, et al. (2006). The anti-inflammatory drug, nimesulide (4-nitro-2-phenoxymethane-sulfoanilide), uncouples mitochondria and induces mitochondrial permeability transition in human hepatoma cells: protection by albumin. J Pharmacol Exp Ther 318: 444-54
5. Birsen Ö Mukaddes G, Hüseyin Ö et al. (2006). The effect of antioxidant caffeic acid phenethyl ester (cape) on some enzyme activities in cisplatin-induced neurotoxicity in rats. Eur J Gen Med 3: 167-72
6. Burgeiro A, Gajate C, Dakirel H, et al. (2011). Involvement of mitochondrial and B-RAF/ERK signaling pathways in berberine-induced apoptosis in human melanoma cells. Anticancer Drugs 22:507-18
7. Collange O, Charles AL, Bouitbir J, et al. (2013). Methylene blue protects liver oxidative capacity after gut ischaemia-reperfusion in the rat. Eur J Vasc Endovasc Surg 45: 168-75
8. Essa MM, Subash S, Braidy N, et al. (2013). Role of NAD(+), oxidative stress, and tryptophan metabolism in autism spectrum disorders. Int J Tryptophan Res 6: 15-28
9. Fiske CH, Subbarow Y. (1925). The colorimetric determination of phosphorous. J Biol Chem 66:375-400
10. Floor E, Wetzel MG. (1998). Increased protein oxidation in human substantia nigra parscompacta in comparison with basal ganglia and prefrontal cortex measured with an improved dinitrophenylhydrazine assay. J Neurochem 70: 268-75
11. Gaona-Gaona L, Molina-Jijón E, Tapia E, et al. (2011). Protective effect of sulforaphane pretreatment against cisplatin-induced liver and mitochondrial oxidant damage in rats. Toxicology 286: 20-7
12. Ghezzi P, Romines B, Fratelli M, et al. (2002). Protein glutathionylation: coupling and uncoupling of glutathione to protein thiol groups in lymphocytes under oxidative stress and HIV infection. Mol Immunol 38: 773-80
13. González-Sánchez I, Lira-Rocha A, Navarrete A, et al. (2012). Synergistic anticancer activity of Thiazolo[5,4-b]quinoline derivative D3CLP in combination with cisplatin in human cervical cancer cells. Anticancer Res 32: 5159-65
14. Habig WH, Pabst M, Jaoby WB. (1974). Glutathione S-Transferase: the first step in mercapturic acid formation. J Biol Chem 249: 7130-9
15. Halliwell B. (2012). Free radicals and antioxidants: updating a personal view. Nutr Rev 70: 257-65
16. Haque R, Bin-Hafeez B, Parvez S, et al. (2003). Aqueous extract of walnut (Juglans regia L.) protects mice against cyclophosphamide induced biochemical toxicity. Hum Exp Toxicol 22: 473-80
17. Hart C, Cohen R, Norwood M, Stebbing J. (2012). The emerging harm of antioxidants in carcinogenesis. Future Oncol 8: 535-48
18. Hassan I, Chibber S, Naseem I. (2010). Ameliorative effect of riboflavin on the cisplatin induced nephrotoxicity and hepatotoxicity under photoillumination. Food Chem Toxicol 48: 2052-8
19. Jastroch M, Divakaruni AS, Mookerjee S, et al. (2010). Mitochondrial proton and electron leaks. Essays Biochem 47: 53-67
20. Kamboj SS, Sandhir R. (2011). Protective effect of N-Acetylcysteine supplementation on mitochondrial oxidative stress and mitochondrial enzymes in cerebral cortex of streptozotocin-Treated diabetic rats. Mitochondrion 11: 214-22
21. King TE. (1967). Preparation of succinate dehydrogenase and reconstitution of reconstitution of succinate oxidase. Meth Enzymol 10: 322-32
22. King TE, Howard RL. (1967). Preparations and properties of soluble NADH dehydrogenases from cardiac muscle. Meth Enzymol 10: 275-94
23. Klein R, Brown D, Turnley AM. (2007). Phenoxodiol protects against cisplatin induced neurite toxicity in a PC-12 cell model. BMC Neurosci 8: 61
24. Kovács AF, Cinatl J Jr. (2002). In vitro cytotoxic dose-relation of cisplatin and sodium thiosulphate in human tongue and oesophageal squamous carcinoma cell lines. J Craniomaxillofac Surg 30: 54-8
25. Krishnan M, Temel JS, Wright AA, et al. (2013). Predicting life expectancy in patients with advanced incurable cancer: a review. J Support Oncol 11: 68-74
26. Kupsch K, Hertel S, Kreutzmann P, et al. (2009). Impairment of mitochondrial function by minocycline. FEBS J 276: 1729-38
27. Lenaz G, Genova ML. (2010). Structure and organization of mitochondrial respiratory complexes: a new understanding of an old subject. Antioxid Redox Signal 12: 961-1008
28. Ling B, Peng F, Alcorn J, et al. (2012). D-Lactate altered mitochondrial energy production in rat brain and heart but not liver. Nutr Metab 9: 6
29. Liu Y, Fiskum G, Schubert D. (2002). Generation of reactive oxygen species by the mitochondrial electron transport chain. J Neurochem 80: 780-7
30. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. (1951). Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-75
31. Lushchak VI. (2012). Glutathione homeostasis and functions: potential targets for medical interventions. J Amino Acids 2012: 736837
32. Mastrocola R, Restivo F, Vercellinatto I, et al. (2005). Oxidative and nitrosative stress in brain mitochondria of diabetic rats. J Endocrinol 187: 37-44
33. Meng F, Sun G, Zhong M, et al. (2013). Anticancer efficacy of cisplatin and trichostatin A or 5-Aza-2′-deoxycytidine on ovarian cancer. Br J Cancer 108: 579-86
34. Muraki K, Koyama R, Honma Y, et al. (2012). Hydration with magnesium and mannitol without furosemide prevents the nephrotoxicity induced by cisplatin and pemetrexed in patients with advanced non-small cell lung cancer. J Thorac Dis 4: 562-8
35. Nadanaciva S, Bernal A, Aggeler R, et al. (2007). Target identification of drug induced mitochondrial toxicity using immunocapture based OXPHOS activity assays. Toxicol In Vitro 21: 902-11
36. Naqshbandi A, Khan W, Rizwan S, Khan F. (2012). Studies on the protective effect of flaxseed oil on cisplatin-induced hepatotoxicity. Hum Exp Toxicol 31: 364-75
37. Nitzsche B, Gloesenkamp C, Schrader M, et al. (2012). Anti-Tumour activity of two novel compounds in cisplatin-resistant testicular germ cell cancer. Br J Cancer 107: 1853-63
38. Ognjanovic BI, Djordjevic NZ, Matic MM, et al. (2012). Lipid peroxidative damage on Cisplatin exposure and alterations in antioxidant defense system in rat kidneys: a possible protective effect of selenium. Int J Mol Sci 13: 1790-803
39. Parvez S, Winkler-Stuck K, Hertel S, et al. (2010). The dopamine-D2-receptor agonist ropinirole dose-dependently blocks the Ca2+-Triggered permeability transition of mitochondria. Biochim Biophys Acta 1797: 1245-50
40. Pinto-Leite R, Arantes-Rodrigues R, Ferreira R, et al. (2014). Temsirolimus improves cytotoxic efficacy of cisplatin and gemcitabine against urinary bladder cancer cell lines. Urol Oncol 32: 41.e11-22
41. Rodrigues MA, Rodrigues JL, Martins NM, et al. (2011). Carvedilol protects against cisplatin-induced oxidative stress, redox state unbalance and apoptosis in rat kidney mitochondria. Chem Biol Interact 189: 45-51
42. Rohlena J, Dong LF, Ralph SJ, Neuzil J. (2011). Anticancer drugs targeting the mitochondrial electron transport chain. Antioxid Redox Signal 15: 2951-74
43. Rosales-Corral SA, Lopez-Armas G, Cruz-Ramos J, et al. (2012). Alterations in lipid levels of mitochondrial membranes induced by amyloid-β: a protective role of melatonin. Int J Alzheimers Dis 2012: 459806
44. Seoane S, Montero JC, Ocaña A, Pandiella A. (2010). Effect of multikinase inhibitors on caspase-independent cell death and DNA damage in HER2-overexpressing breast cancer cells. J Natl Cancer Inst 102: 1432-46
45. Singh R, Sharma P. (2011). Hepatoprotective effect of curcumin on lindane-induced oxidative stress in male Wistar rats. Toxicol Int 18: 124-9
46. Su YC, Hong JR. (2010). Betanodavirus B2 causes ATP depletion-induced cell death via mitochondrial targeting and complex II inhibition in vitro and in vivo. J Biol Chem 285:39801-10
47. Ta LE, Schmelzer JD, Bieber AJ, et al. (2013). A novel and selective poly (ADP-ribose) polymerase inhibitor ameliorates chemotherapy-induced painful neuropathy. PLoS One 8: e54161
48. Tabassum H, Parvez S, Pasha ST, et al. (2010). Protective effect of lipoic acid against methotrexate-induced oxidative stress in liver mitochondria. Food Chem Toxicol 48: 1973-9
49. Tanaka M, Kataoka H, Yano S, et al. (2013). Anti-cancer effects of newly developed chemotherapeutic agent, glycoconjugated palladium (II) complex, against cisplatin-resistant gastric cancer cells. BMC Cancer 13: 237
50. Wang M, Liu ZM, Li XC, et al. (2013a). Activation of ERK1/2 and Akt is associated with cisplatin resistance in human lung cancer cells. J Chemother 25: 162-9
51. Wang P, Zhang P, Huang J, et al. (2013b). Trichostatin A protects against cisplatin-induced ototoxicity by regulating expression of genes related to apoptosis and synaptic function. Neurotoxicology 37: 51-62
52. Waseem M, Parvez S. (2013). Mitochondrial dysfunction mediated cisplatin induced toxicity: modulatory role of curcumin. Food Chem Toxicol 53: 334-42
53. Zsengellér ZK, Ellezian L, Brown D, et al. (2012). Cisplatin nephrotoxicity involves mitochondrial injury with impaired tubular mitochondrial enzyme activity. J Histochem Cytochem 60: 521-9