Protective effect of sulforaphane pretreatment against cisplatin-induced liver and mitochondrial oxidant damage in rats

Toxicology

Volumn 286, Issue 1-3, 2011, Pages 20-27

  Gaona Gaona, Leobardo ^a   Molina Jijón, Eduardo ^a   Tapia, Edilia ^b   Zazueta, Cecilia ^b   Hernández Pando, Rogelio ^c   Calderón Oliver, Mariel ^a   Zarco Márquez, Guillermo ^a   Pinzón, Enrique ^d   Pedraza Chaverri, José ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b INSTITUTO NACIONAL DE CARDIOLOGÍA IGNACIO CHÁVEZ   (Mexico)

^c INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

^d UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Cisplatin; Hepatotoxicity; Mitochondrial complex; Oxidant stress; Oxygen consumption; Sulforaphane

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CATALASE; CISPLATIN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; PEROXYNITRITE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SULFORAPHANE; SUPEROXIDE DISMUTASE; UBIQUINOL CYTOCHROME C REDUCTASE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY WEIGHT; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SUBSTRATE; HISTOPATHOLOGY; IN VITRO STUDY; LIPID PEROXIDATION; LIVER HOMOGENATE; LIVER INJURY; LIVER MITOCHONDRION; LIVER PROTECTION; LIVER TOXICITY; LIVER WEIGHT; MALE; NONHUMAN; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN CARBONYLATION; RAT;

RATTUS; RATTUS NORVEGICUS;

EID: 79959221211     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2011.04.014     Document Type: Article

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