Towards the design of hypolipidaemic peptides: Deoxycholate binding affinity of hydrophobic peptide aggregates of casein plastein

Journal of Functional Foods

Volumn 18, Issue , 2015, Pages 129-136

  Mohan, Aishwarya ^a   Udenigwe, Chibuike C ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Aggregation; Casein; Deoxycholate; Hydrophobicity; Peptides; Plastein

Indexed keywords

EID: 84942518695     PISSN: 17564646     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jff.2015.06.064     Document Type: Article

References (24)

1. Barbana C., Boucher A.C., Boye J.I. In vitro binding of bile salts by lentil flours, lentil protein concentrates and lentil protein hydrolysates. Food Research International 2011, 44:174-180.
2. Bernstein C., Holubec H., Bhattacharyya A.K., Nguyen H., Payne C.M., Zaitlin B., Bernstein H. Carcinogenicity of deoxycholate, a secondary bile acid. Archives of Toxicology 2011, 85:863-871.
3. Brownsell V.L., Williams R.J.H., Andrews A.T. Application of the plastein reaction to mycoprotein: II. Plastein properties. Food Chemistry 2001, 72:337-346.
4. Chen Z.Y., Ma K.Y., Liang Y., Peng C., Zuo Y. Role and classification of cholesterol-lowering functional foods. Journal of Functional Foods 2011, 3:61-69.
5. Choi S.K., Adachi M., Utsumi S. Identification of the bile acid-binding region in the soy glycinin A1aB1b subunit. Bioscience, Biotechnology, and Biochemistry 2002, 66:2395-2401.
6. Cleeman J.I., Grundy S.M., Becker D., Clark L.T. Expert panel on detection, evaluation and treatment of high blood cholesterol in adults. Executive summary of the third report of the National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP III). Journal of the American Medical Association 2001, 285:2486-2497.
7. Gong M., Mohan A., Gibson A., Udenigwe C.C. Mechanisms of plastein formation, and prospective food and nutraceutical applications of the peptide aggregates. Biotechnology Reports 2015, 5:63-69.
8. Higaki N., Sato K., Suda H., Suzuka T., Komori T., Saeki T., Nakamura Y., Ohtsuki K., Iwami K., Kanamoto R. Evidence for the existence of a soybean resistant protein that captures bile acid and stimulates its fecal excretion. Bioscience, Biotechnology, and Biochemistry 2006, 70:2844-2852.
9. Horax R., Hettiarachchy N.S., Chen P., Jalaluddin M. Preparation and characterization of protein isolate from cowpea (Vigna unguiculata L. Walp). Journal of Food Science 2004, 69:114-118.
10. Howard A., Udenigwe C.C. Mechanisms and prospects of food protein hydrolysates and peptide-induced hypolipidaemia. Food & Function 2013, 4:40-51.
11. Insull W. Clinical utility of bile acid sequestrants in the treatment of dyslipidemia: A scientific review. Southern Medical Journal 2006, 99:257-273.
12. Ma Y., Xiong Y.L. Antioxidant and bile acid binding activity of buckwheat protein in vitro digests. Journal of Agricultural and Food Chemistry 2009, 57:4372-4380.
13. Matsuoka R., Shirouchi B., Kawamura S., Baba S., Shiratake S., Nagata K., Imaizumi K., Sato M. Dietary egg white protein inhibits lymphatic lipid transport in thoracic lymph duct-cannulated rats. Journal of Agricultural and Food Chemistry 2014, 62:10694-10700.
14. Nielsen P.M., Petersen D., Dambmann C. Improved method for determining food protein degree of hydrolysis. Journal of Food Science 2001, 66:642-646.
15. Staels B., Handelsman Y., Fonseca V. Bile acid sequestrants for lipid and glucose control. Current Diabetes Reports 2010, 10:70-77.
16. Sun H., Zhao X.H. Angiotensin I converting enzyme inhibition and enzymatic resistance in vitro of casein hydrolysate treated by plastein reaction and fractionated with ethanol/water or methanol/water. International Dairy Journal 2012, 24:27-32.
17. Synowiecki J., Jagietka R., Shahidi F. Preparation of hydrolysates from bovine red blood cells and their debittering following plastein reaction. Food Chemistry 1996, 57:435-439.
18. Udenigwe C.C., Mohan A., Wu S. Peptide aggregation during plastein reaction enhanced bile acid-binding capacity of enzymatic chicken meat hydrolysates. Journal of Food Biochemistry 2015, 39:344-348.
19. Udenigwe C.C., Rouvinen-Watt K. The role of food peptides in lipid metabolism during dyslipidemia and associated health conditions. International Journal of Molecular Sciences 2015, 16:9303-9313.
20. Udenigwe C.C., Wu S., Drummond K., Gong M. Revisiting the prospects of plastein: Thermal and simulated gastric stability in relation to the antioxidative capacity of casein plastein. Journal of Agricultural and Food Chemistry 2014, 62:130-135.
21. World Health Organization World health statistics 2012, Switzerland, Geneva.
22. Yamashita M., Arai S., Tsai S.J., Fujimaki M. Plastein reaction as a method for enhancing the sulfur-containing amino acid level of soybean protein. Journal of Agricultural and Food Chemistry 1971, 19:1151-1154.
23. Yoshie-Stark Y., Wada Y., Wäsche A. Chemical composition, functional properties, and bioactivities of rapeseed protein isolates. Food Chemistry 2008, 107:32-39.
24. Zhao X.H., Wu D., Li T.J. Preparation and radical scavenging activity of papain-catalyzed casein plasteins. Dairy Science & Technology 2010, 90:521-535.