A Compartmental Analysis for Morphine and Its Metabolites in Young Children After a Single Oral Dose

Clinical Pharmacokinetics

Volumn 54, Issue 10, 2015, Pages 1083-1090

  Velez de Mendizabal, Nieves ^a,b   Jimenez Mendez, Ricardo ^c,d,e   Cooke, Erin ^c,d   Montgomery, Carolyne J ^c,d   Dawes, Joy ^c,d   Rieder, Michael J ^f   Aleksa, Katarina ^g   Koren, Gideon ^g   Jacobo Cabral, Carlos O ^h   Gonzalez Ramirez, Rodrigo ^h   Castañeda Hernandez, Gilberto ^h   Carleton, Bruce C ^c,d,e  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Indiana Clinical and Translational Sciences Institute (CTSI)   (United States)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d BC CHILDREN S HOSPITAL   (Canada)

^e UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^f UNIVERSITY OF WESTERN ONTARIO   (Canada)

^g HOSPITAL FOR SICK CHILDREN   (Canada)

^h DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

MORPHINE; MORPHINE 3 GLUCURONIDE; MORPHINE 6 GLUCURONIDE; OPIATE; CODEINE; CODEINE-6-GLUCURONIDE; CYTOCHROME P450 2D6; MORPHINE DERIVATIVE; MORPHINE-3-GLUCURONIDE; MORPHINE-6-GLUCURONIDE; NARCOTIC ANALGESIC AGENT;

ANALGESIA; ANALGESIC ACTIVITY; ARTICLE; BLOOD SAMPLING; CHEMICAL ANALYSIS; CHILD; CLINICAL ARTICLE; CLINICAL CLASSIFICATION; CLINICAL EVALUATION; CLINICAL TRIAL; COMPARTMENT MODEL; CONTROLLED STUDY; DAY CARE; DRUG BLOOD LEVEL; FEMALE; FOLLOW UP; HUMAN; MALE; MEDICAL INFORMATION; OUTPATIENT CARE; PAIN ASSESSMENT; PEDIATRIC HOSPITAL; POPULATION; POSTOPERATIVE PAIN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; ANALOGS AND DERIVATIVES; BIOLOGICAL MODEL; BLOOD; GENETIC POLYMORPHISM; GENETICS; METABOLISM; ORAL DRUG ADMINISTRATION; PAIN, POSTOPERATIVE; PRESCHOOL CHILD; TERTIARY CARE CENTER;

ADMINISTRATION, ORAL; ANALGESICS, OPIOID; CHILD; CHILD, PRESCHOOL; CODEINE; CYTOCHROME P-450 CYP2D6; FEMALE; HUMANS; MALE; MODELS, BIOLOGICAL; MORPHINE; MORPHINE DERIVATIVES; PAIN, POSTOPERATIVE; POLYMORPHISM, GENETIC; TERTIARY CARE CENTERS;

EID: 84942505368     PISSN: 03125963     EISSN: 11791926     Source Type: Journal    
DOI: 10.1007/s40262-015-0256-4     Document Type: Article

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