Pharmacokinetic modeling to predict morphine and morphinc-6-glucuronide plasma concentrations in healthy young volunteers

Clinical Pharmacology and Therapeutics

Volumn 72, Issue 2, 2002, Pages 151-162

  Lötsch, Jörn ^a,b   Skarke, Carsten ^a,b   Schmidt, Helmut ^a,b   Liefhold, Jürgen ^a,b   Geisslinger, Gerd ^a,b  

^a GOETHE UNIVERSITY   (Germany)

^b MUNDIPHARMA GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DEUTERIUM; MORPHINE 6 GLUCURONIDE; MORPHINE SULFATE; MSI 10;

ACCURACY; ADULT; AREA UNDER THE CURVE; ARTICLE; BOLUS INJECTION; COMPARTMENT MODEL; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG INDUCED DISEASE; DRUG METABOLISM; FEMALE; HUMAN; HUMAN EXPERIMENT; ISOTOPE LABELING; KIDNEY CLEARANCE; MALE; METABOLIC CLEARANCE RATE; NORMAL HUMAN; PREDICTION; PRIORITY JOURNAL; VOLUNTEER;

ADULT; ANALGESICS, OPIOID; FEMALE; HUMANS; INJECTIONS, INTRAVENOUS; MALE; MODELS, STATISTICAL; MORPHINE; MORPHINE DERIVATIVES; NARCOTICS; REFERENCE VALUES; TIME FACTORS;

EID: 0036694283     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1067/mcp.2002.126172     Document Type: Article

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