Not all SCID pigs are created equally: Two independent mutations in the artemis gene cause SCID in pigs

Journal of Immunology

Volumn 195, Issue 7, 2015, Pages 3171-3179

  Waide, Emily H ^a   Dekkers, Jack C M ^a   Ross, Jason W ^a   Rowland, Raymond R R ^b   Wyatt, Carol R ^b   Ewen, Catherine L ^b   Evans, Alyssa B ^a   Thekkoot, Dinesh M ^a   Boddicker, Nicholas J ^c   Serão, Nick V L ^a   Ellinwood, N Matthew ^a   Tuggle, Christopher K ^a  

^a IOWA STATE UNIVERSITY   (United States)

^b KANSAS STATE UNIVERSITY   (United States)

^c GENESUS INC   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTEMIS GENE; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; DNA DAMAGE; DNA END JOINING REPAIR; DNA REPAIR; FIBROBLAST; GENE MAPPING; GENE MUTATION; HETEROZYGOSITY; HOMOZYGOSITY; IMMUNOPHENOTYPING; INTRON; MACROPHAGE; NONHUMAN; OPEN READING FRAME; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RADIOSENSITIVITY; RAG1 GENE; RAG2 GENE; REAL TIME POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; SEVERE COMBINED IMMUNODEFICIENCY; SINGLE NUCLEOTIDE POLYMORPHISM; T LYMPHOCYTE; ADAPTIVE IMMUNITY; ANIMAL; CHROMOSOMAL MAPPING; DNA SEQUENCE; GENETICS; HAPLOTYPE; IMMUNOLOGY; NATURAL KILLER CELL; NUCLEOTIDE SEQUENCE; PHENOTYPE; PIG; RADIATION TOLERANCE;

DNA LIGASE; NUCLEAR PROTEIN;

ADAPTIVE IMMUNITY; ANIMALS; B-LYMPHOCYTES; BASE SEQUENCE; CHROMOSOME MAPPING; DNA REPAIR ENZYMES; HAPLOTYPES; KILLER CELLS, NATURAL; NUCLEAR PROTEINS; PHENOTYPE; RADIATION TOLERANCE; SEQUENCE ANALYSIS, DNA; SEVERE COMBINED IMMUNODEFICIENCY; SUS SCROFA; T-LYMPHOCYTES;

EID: 84942475255     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1501132     Document Type: Article

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