Glycycoumarin ameliorates alcohol-induced hepatotoxicity via activation of Nrf2 and autophagy

Free Radical Biology and Medicine

Volumn 89, Issue , 2015, Pages 135-146

  Song, Xinhua ^a   Yin, Shutao ^a   Huo, Yazhen ^a   Liang, Min ^a   Fan, Lihong ^a   Ye, Min ^b   Hu, Hongbo ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Alcoholic liverinjury; Autophagy; Freeradicals; Glycycoumarin; Licorice; Nrf2

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; COUMARIN DERIVATIVE; GLYCYCOUMARIN; LIVER PROTECTIVE AGENT; PROTEIN P62; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; ALCOHOL; CENTRAL DEPRESSANT AGENT; MESSENGER RNA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL LIVER CIRRHOSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; AUTOPHAGY; CONTROLLED STUDY; DRUG MECHANISM; GLYCYRRHIZA; HISTOPATHOLOGY; HUMAN; HUMAN CELL; LIPID STORAGE; LIVER PROTECTION; LIVER TOXICITY; MOUSE; NONHUMAN; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; APOPTOSIS; C57BL MOUSE; CARCINOMA, HEPATOCELLULAR; CELL CULTURE; CELL PROLIFERATION; CHEMICALLY INDUCED; DRUG EFFECTS; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; LIVER; LIVER NEOPLASMS; MALE; METABOLISM; OXIDATIVE STRESS; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; AUTOPHAGY; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM DEPRESSANTS; COUMARINS; ETHANOL; FLUORESCENT ANTIBODY TECHNIQUE; LIVER; LIVER NEOPLASMS; MALE; MICE; MICE, INBRED C57BL; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84942409767     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.07.006     Document Type: Article

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