Isoangustone A induces apoptosis in SW480 human colorectal adenocarcinoma cells by disrupting mitochondrial functions

Fitoterapia

Volumn 94, Issue , 2014, Pages 36-47

  Huang, Wei ^a   Tang, Shunan ^a   Qiao, Xue ^a   Ma, Wanwan ^a   Ji, Shuai ^a   Wang, Kui ^a   Ye, Min ^a   Yu, Siwang ^a  

^a PEKING UNIVERSITY   (China)

Author keywords

Apoptosis; Colorectal cancer; Isoangustone A; Mitochondrial outer membrane permeabilization

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTINEOPLASTIC AGENT; APIOSIDE; BETA ACTIN; CASPASE 3; CASPASE 9; CYTOCHROME C; GLYCYRRHETINIC ACID; ISOANGUSTONE A; ISOLIQUIRITIGENIN; ISOLIQUIRITIN; LIQUIRITIGENIN; LIQUIRITIN; MAMMALIAN TARGET OF RAPAMYCIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; ONONIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG; CASPASE; CASPASE INHIBITOR; ISOFLAVONE DERIVATIVE; PLANT EXTRACT;

ADENOCARCINOMA CELL LINE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL STRUCTURE; CELL VIABILITY; CELLULAR DISTRIBUTION; COLORECTAL CARCINOMA; CONTROLLED STUDY; CYTOTOXICITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG SCREENING; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GLYCYRRHIZA URALENSIS; HUMAN; HUMAN CELL; INTRACELLULAR SPACE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION SWELLING; NONHUMAN; OUTER MEMBRANE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; CELL CYCLE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; ISOLATION AND PURIFICATION; METABOLISM; MITOCHONDRION; TUMOR CELL LINE;

GLYCYRRHIZA; RATTUS;

APOPTOSIS; CASPASE INHIBITORS; CASPASES; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; CYTOCHROMES C; GLYCYRRHIZA URALENSIS; HUMANS; ISOFLAVONES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; PLANT EXTRACTS; SIGNAL TRANSDUCTION;

EID: 84894265538     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2014.01.016     Document Type: Article

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