Upregulation of miR-34a-5p antagonizes AFB1-induced genotoxicity in F344 rat liver

Toxicon

Volumn 106, Issue , 2015, Pages 46-56

  Liu, Caixia ^a,b   Yu, Haohui ^a,c   Zhang, Yan ^a   Li, Daochuan ^a   Xing, Xiumei ^a   Chen, Liping ^a   Zeng, Xiaowen ^a   Xu, Dandan ^a   Fan, Qiming ^a   Xiao, Yongmei ^a   Chen, Wen ^a   Wang, Qing ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

^c THE FIRST AFFILIATED HOSPITAL OF JINAN UNIVERSITY   (China)

Author keywords

Aflatoxin B1; DNA damage; Genotoxicity; miR 34a 5p; P53

Indexed keywords

AFLATOXIN B1; ALANINE AMINOTRANSFERASE; MICRORNA; MICRORNA 200B 3P; MICRORNA 34A 5P; MICRORNA 429; PROTEIN P53; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; CCND1 PROTEIN, RAT; CCNE2 PROTEIN, RAT; CYCLIN D1; CYCLIN E; MIRN34 MICRORNA, RAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CCND1 GENE; CCNE2 GENE; CELL CYCLE; CELL CYCLE CHECKPOINT; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DOWN REGULATION; ENZYME ACTIVITY; G0 PHASE CELL CYCLE CHECKPOINT; GENE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENOTOXICITY; HIGH THROUGHPUT SEQUENCING; IN VITRO STUDY; IN VIVO STUDY; LIVER TOXICITY; MALE; MET GENE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; DRUG EFFECTS; FISCHER 344 RAT; GENE EXPRESSION PROFILING; GENETICS; LIVER; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE;

AFLATOXIN B1; ANIMALS; BIOMARKERS; CELL LINE, TUMOR; CYCLIN D1; CYCLIN E; DNA DAMAGE; DNA REPAIR; GENE EXPRESSION PROFILING; LIVER; MICRORNAS; RATS; RATS, INBRED F344; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 84942326906     PISSN: 00410101     EISSN: 18793150     Source Type: Journal    
DOI: 10.1016/j.toxicon.2015.09.016     Document Type: Article

References (45)

1. F. Aguilar, S.P. Hussain, and P. Cerutti Aflatoxin B1 induces the transversion of G - >T in codon 249 of the p53 tumor suppressor gene in human hepatocytes Proc. Natl. Acad. Sci. U. S. A. 90 1993 8586 8590
2. S. Audic, and J.M. Claverie The significance of digital gene expression profiles Genome Res. 7 1997 986 995
3. R. Baan, Y. Grosse, K. Straif, B. Secretan, F. El Ghissassi, V. Bouvard, L. Benbrahim-Tallaa, N. Guha, C. Freeman, L. Galichet, V. Cogliano Group, W.H.O.I.A.f.R.o.C.M.W A review of human carcinogens - Part F: chemical agents and related occupations Lancet. Oncol. 10 2009 1143 1144
4. T. Behne, and M.S. Copur Biomarkers for hepatocellular carcinoma Int. J. Hepatol. 2012 2012 859076
5. D. Benford, J.C. Leblanc, and R.W. Setzer Application of the margin of exposure (MoE) approach to substances in food that are genotoxic and carcinogenic: example: aflatoxin B1 (AFB1) Food Chem. Toxicol. Int. J. Publ. Br. Ind. Biol. Res. Assoc. 48 Suppl. 1 2010 S34 S41
6. N. Bushati, and S.M. Cohen microRNA functions Annu. Rev. Cell Dev. Biol. 23 2007 175 205
7. F. Chen, and S.J. Hu Effect of microRNA-34a in cell cycle, differentiation, and apoptosis: a review J. Biochem. Mol. Toxicol. 26 2012 79 86
8. T. Chen The role of microRNA in chemical carcinogenesis J. Environ. Sci. Health C Environ. Carcinog. Ecotoxicol. Rev. 28 2010 89 124
9. X. Chen, J. Yan, and T. Chen Expression level of miR-34a rather than P53 gene status correlates with mutability in related human lymphoblast cell lines Mol. Carcinog. 51 2012 674 677
10. A.A. Chuturgoon, A. Phulukdaree, and D. Moodley Fumonisin B(1) modulates expression of human cytochrome P450 1b1 in human hepatoma (Hepg2) cells by repressing Mir-27b Toxicol. Lett. 227 2014 50 55
11. W.B. Coleman Mechanisms of human hepatocarcinogenesis Curr. Mol. Med. 3 2003 573 588
12. A.P. DeCaprio Axonal swellings vs atrophy: what is the relevance to gamma-diketone peripheral neuropathy? Commentary on forum position paper Neurotoxicology 18 1997 25 27 discussion 37-40
13. A.P. DeCaprio Biomarkers: coming of age for environmental health and risk assessment Environ. Sci. Technol. 31 1997 1837 1848
14. E. Elyakim, E. Sitbon, A. Faerman, S. Tabak, E. Montia, L. Belanis, A. Dov, E.G. Marcusson, C.F. Bennett, A. Chajut, D. Cohen, and N. Yerushalmi hsa-miR-191 is a candidate oncogene target for hepatocellular carcinoma therapy Cancer Res. 70 2010 8077 8087
15. Y. Fang, Y. Feng, T. Wu, S. Srinivas, W. Yang, J. Fan, C. Yang, and S. Wang Aflatoxin B1 negatively regulates Wnt/beta-catenin signaling pathway through activating miR-33a PLoS One 8 2013 e73004
16. M. Fenech, W.P. Chang, M. Kirsch-Volders, N. Holland, S. Bonassi, E. Zeiger Project H.U.M HUMN project: detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures Mutat. Res. 534 2003 65 75
17. T. Ghawanmeh, U. Thunberg, J. Castro, F. Murray, and N. Laytragoon-Lewin miR-34a expression, cell cycle arrest and cell death of malignant mesothelioma cells upon treatment with radiation, docetaxel or combination treatment Oncology 81 2011 330 335
18. L. He, and G.J. Hannon MicroRNAs: small RNAs with a big role in gene regulation Nat. Rev. Genet. 5 2004 522 531
19. X. Ji, Z. Wang, A. Geamanu, A. Goja, F.H. Sarkar, and S.V. Gupta Delta-tocotrienol suppresses Notch-1 pathway by upregulating miR-34a in nonsmall cell lung cancer cells Int. J. Cancer. J. Int. du cancer 131 2012 2668 2677
20. A.C. Joerger, and A.R. Fersht Structure-function-rescue: the diverse nature of common p53 cancer mutants Oncogene 26 2007 2226 2242
21. T.W. Kensler, B.D. Roebuck, G.N. Wogan, and J.D. Groopman Aflatoxin: a 50-year odyssey of mechanistic and translational toxicology Toxicol. Sci. Off. J. Soc. Toxicol. 120 Suppl. 1 2011 S28 S48
22. T. Kim, A. Veronese, F. Pichiorri, T.J. Lee, Y.J. Jeon, S. Volinia, P. Pineau, A. Marchio, J. Palatini, S.S. Suh, H. Alder, C.G. Liu, A. Dejean, and C.M. Croce p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2 J. Exp. Med. 208 2011 875 883
23. C. Koufaris, J. Wright, R.A. Currie, and N.J. Gooderham Hepatic microRNA profiles offer predictive and mechanistic insights after exposure to genotoxic and epigenetic hepatocarcinogens Toxicol. Sci. Off. J. Soc. Toxicol. 128 2012 532 543
24. Y. Li, J. Zhang, L. Zhang, M. Si, H. Yin, and J. Li Diallyl trisulfide inhibits proliferation, invasion and angiogenesis of osteosarcoma cells by switching on suppressor microRNAs and inactivating of Notch-1 signaling Carcinogenesis 34 2013 1601 1610
25. Y. Liu, and F. Wu Global burden of aflatoxin-induced hepatocellular carcinoma: a risk assessment Environ. Health Perspect. 118 2010 818 824
26. Z. Lu, D. Jiao, J. Qiao, S. Yang, M. Yan, S. Cui, and Z. Liu Restin suppressed epithelial-mesenchymal transition and tumor metastasis in breast cancer cells through upregulating mir-200a/b expression via association with p73 Mol. Cancer 14 2015 102
27. Z. Luo, L. Zhang, Z. Li, X. Li, G. Li, H. Yu, C. Jiang, Y. Dai, X. Guo, J. Xiang, and G. Li An in silico analysis of dynamic changes in microRNA expression profiles in stepwise development of nasopharyngeal carcinoma BMC Med. Genomics 5 2012 3
28. A.I. Malik, A. Williams, C.L. Lemieux, P.A. White, and C.L. Yauk Hepatic mRNA, microRNA, and miR-34a-target responses in mice after 28 days exposure to doses of benzo(a)pyrene that elicit DNA damage and mutation Environ. Mol. Mutagen. 53 2012 10 21
29. S. Mohd-Redzwan, R. Jamaluddin, M.S. Abd-Mutalib, and Z. Ahmad A mini review on aflatoxin exposure in Malaysia: past, present and future Front. Microbiol. 4 2013 334
30. N. Okada, C.P. Lin, M.C. Ribeiro, A. Biton, G. Lai, X. He, P. Bu, H. Vogel, D.M. Jablons, A.C. Keller, J.E. Wilkinson, B. He, T.P. Speed, and L. He A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression Genes Dev. 28 2014 438 450
31. Y. Peng, J.J. Guo, Y.M. Liu, and X.L. Wu MicroRNA-34A inhibits the growth, invasion and metastasis of gastric cancer by targeting PDGFR and MET expression Biosci. Rep. 34 2014
32. I.P. Pogribny, and I. Rusyn Environmental toxicants, epigenetics, and cancer Adv. Exp. Med. Biol. 754 2013 215 232
33. I.P. Pogribny, A. Starlard-Davenport, V.P. Tryndyak, T. Han, S.A. Ross, I. Rusyn, and F.A. Beland Difference in expression of hepatic microRNAs miR-29c, miR-34a, miR-155, and miR-200b is associated with strain-specific susceptibility to dietary nonalcoholic steatohepatitis in mice Laboratory investigation J. Tech. Methods Pathol. 90 2010 1437 1446
34. M.J. Ramaiah, S.N. Pushpavalli, A. Lavanya, K. Bhadra, V. Haritha, N. Patel, J.R. Tamboli, A. Kamal, U. Bhadra, and M. Pal-Bhadra Novel anthranilamide-pyrazolo[1,5-a]pyrimidine conjugates modulate the expression of p53-MYCN associated micro RNAs in neuroblastoma cells and cause cell cycle arrest and apoptosis Bioorg. Med. Chem. Lett. 23 2013 5699 5706
35. G. Ramakrishna, A. Rastogi, N. Trehanpati, B. Sen, R. Khosla, and S.K. Sarin From cirrhosis to hepatocellular carcinoma: new molecular insights on inflammation and cellular senescence Liver Cancer 2 2013 367 383
36. T. Sakurai, G. He, A. Matsuzawa, G.Y. Yu, S. Maeda, G. Hardiman, and M. Karin Hepatocyte necrosis induced by oxidative stress and IL-1 alpha release mediate carcinogen-induced compensatory proliferation and liver tumorigenesis Cancer Cell 14 2008 156 165
37. M.Y. Siraj, A.W. Hayes, P.D. Unger, G.R. Hogan, N.J. Ryan, and B.B. Wray Analysis of aflatoxin B1 in human tissues with high-pressure liquid chromatography Toxicol. Appl. Pharmacol. 58 1981 422 430
38. M.E. Smela, S.S. Currier, E.A. Bailey, and J.M. Essigmann The chemistry and biology of aflatoxin B(1): from mutational spectrometry to carcinogenesis Carcinogenesis 22 2001 535 545
39. T. Sukata, K. Sumida, M. Kushida, K. Ogata, K. Miyata, S. Yabushita, and S. Uwagawa Circulating microRNAs, possible indicators of progress of rat hepatocarcinogenesis from early stages Toxicol. Lett. 200 2011 46 52
40. J. Trebicka, E. Anadol, N. Elfimova, I. Strack, M. Roggendorf, S. Viazov, I. Wedemeyer, U. Drebber, J. Rockstroh, T. Sauerbruch, H.P. Dienes, and M. Odenthal Hepatic and serum levels of miR-122 after chronic HCV-induced fibrosis J. Hepatol. 58 2013 234 239
41. V.P. Tryndyak, J.R. Latendresse, B. Montgomery, S.A. Ross, F.A. Beland, I. Rusyn, and I.P. Pogribny Plasma microRNAs are sensitive indicators of inter-strain differences in the severity of liver injury induced in mice by a choline- and folate-deficient diet Toxicol. Appl. Pharmacol. 262 2012 52 59
42. K. Wang, S. Zhang, B. Marzolf, P. Troisch, A. Brightman, Z. Hu, L.E. Hood, and D.J. Galas Circulating microRNAs, potential biomarkers for drug-induced liver injury Proc. Natl. Acad. Sci. U. S. A. 106 2009 4402 4407
43. S. Yan, J. Wang, W. Zhang, and J. Dai Circulating microRNA profiles altered in mice after 28 d exposure to perfluorooctanoic acid Toxicol. Lett. 224 2014 24 31
44. C.F. Yang, J. Liu, S. Wasser, H.M. Shen, C.E. Tan, and C.N. Ong Inhibition of ebselen on aflatoxin B(1)-induced hepatocarcinogenesis in Fischer 344 rats Carcinogenesis 21 2000 2237 2243
45. W. Yang, J. Lian, Y. Feng, S. Srinivas, Z. Guo, H. Zhong, Z. Zhuang, and S. Wang Genome-wide miRNA-profiling of aflatoxin B1-induced hepatic injury using deep sequencing Toxicol. Lett. 226 2014 140 149