Deficiency in the lipid exporter ABCA1 impairs retrograde sterol movement and disrupts sterol sensing at the endoplasmic reticulum

Journal of Biological Chemistry

Volumn 290, Issue 39, 2015, Pages 23464-23477

  Yamauchi, Yoshio ^a   Iwamoto, Noriyuki ^c   Rogers, Maximillian A ^b   Abe Dohmae, Sumiko ^c   Fujimoto, Toyoshi ^a   Chang, Catherine C Y ^b   Ishigami, Masato ^d   Kishimoto, Takuma ^e   Kobayashi, Toshihide ^e   Ueda, Kazumitsu ^d   Furukawa, Koichi ^a   Chang, Ta Yuan ^b   Yokoyama, Shinji ^f  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

^c NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^d KYOTO UNIVERSITY   (Japan)

^e RIKEN   (Japan)

^f CHUBU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; CHOLESTEROL; ENZYME INHIBITION; LIPOPROTEINS; MACROMOLECULES; PHOSPHOLIPIDS; PHYSIOLOGY;

APOLIPOPROTEIN A-I; ATP BINDING CASSETTE TRANSPORTERS; CELLULAR CHOLESTEROL; CHOLESTEROL EFFLUX; ENDOPLASMIC RETICULUM; EXPERIMENTAL EVIDENCE; HIGH-DENSITY LIPOPROTEINS; STEROL ESTERIFICATION;

ALCOHOLS;

ABC TRANSPORTER A1; ADENOSINE TRIPHOSPHATASE; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; ABCA1 PROTEIN, MOUSE; SREBF2 PROTEIN, MOUSE; STEROL;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CHOLESTEROL ESTERIFICATION; CHOLESTEROL METABOLISM; CHOLESTEROL TRANSPORT; CLATHRIN INDEPENDENT ENDOCYTOSIS; CONTROLLED STUDY; ENDOCYTOSIS; ENDOPLASMIC RETICULUM; LIPID COMPOSITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RETROGRADE STEROL TRANSPORT; STEROL SENSING; ANIMAL; CELL CULTURE; LIPID METABOLISM; METABOLISM; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; ATP BINDING CASSETTE TRANSPORTER 1; BIOLOGICAL TRANSPORT; CELLS, CULTURED; ENDOPLASMIC RETICULUM; LIPID METABOLISM; MICE; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; STEROLS;

EID: 84942321174     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.662668     Document Type: Article

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