Shp-2 contributes to anti-RSV activity in human pulmonary alveolar epithelial cells by interfering with the IFN-α-induced Jak/Stat1 pathway

Journal of Cellular and Molecular Medicine

Volumn 19, Issue 10, 2015, Pages 2432-2440

  Wang, Saisai ^a,b   Zheng, Gang ^a   Zhao, Lifang ^c   Xu, Feng ^c   Qian, Jing ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Interferon; Jak Stat; Respiratory syncytial virus; Src homology phosphotyrosyl phosphatase 2

Indexed keywords

ALPHA INTERFERON; JANUS KINASE; PROTEIN TYROSINE PHOSPHATASE SHP 1; STAT PROTEIN; PHOSPHOTYROSINE; PROTEIN TYROSINE PHOSPHATASE SHP 2; PTPN11 PROTEIN, HUMAN; STAT1 PROTEIN; STAT1 PROTEIN, HUMAN;

A549 CELL LINE; ARTICLE; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; HUMAN RESPIRATORY SYNCYTIAL VIRUS; LUNG ALVEOLUS EPITHELIUM CELL; NONHUMAN; PLAQUE ASSAY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RESPIRATORY SYNCYTIAL VIRUS INFECTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRUS REPLICATION; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; BIOLOGICAL MODEL; CELL LINE; DRUG EFFECTS; GENE EXPRESSION REGULATION; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; VIROLOGY;

ALVEOLAR EPITHELIAL CELLS; CELL LINE; GENE EXPRESSION REGULATION; HUMANS; INTERFERON-ALPHA; JANUS KINASES; MODELS, BIOLOGICAL; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUSES; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; VIRUS REPLICATION;

EID: 84942317405     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/jcmm.12629     Document Type: Article

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