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Volumn 16, Issue 1, 2015, Pages

Deep sequencing and de novo assembly of the mouse oocyte transcriptome define the contribution of transcription to the DNA methylation landscape

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE DEMETHYLASE; HISTONE H3; TRANSCRIPTOME; CELL CYCLE PROTEIN; PLAGL1 PROTEIN, MOUSE; TRANSCRIPTION FACTOR; TRANSPOSON;

EID: 84942313259     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-015-0769-z     Document Type: Article
Times cited : (152)

References (50)
  • 2
    • 84655164284 scopus 로고    scopus 로고
    • De novo DNA methylation: a germ cell perspective
    • Smallwood SA, Kelsey G. De novo DNA methylation: a germ cell perspective. Trends Genet. 2012;28:33-42.
    • (2012) Trends Genet. , vol.28 , pp. 33-42
    • Smallwood, S.A.1    Kelsey, G.2
  • 3
    • 79960530899 scopus 로고    scopus 로고
    • Genomic imprinting: the emergence of an epigenetic paradigm
    • Ferguson-Smith AC. Genomic imprinting: the emergence of an epigenetic paradigm. Nat Rev Genet. 2011;12:565-75.
    • (2011) Nat Rev Genet. , vol.12 , pp. 565-575
    • Ferguson-Smith, A.C.1
  • 4
    • 84857467013 scopus 로고    scopus 로고
    • Contribution of intragenic DNA methylation in mouse gametic DNA methylomes to establish oocyte-specific heritable marks
    • Kobayashi H, Sakurai T, Imai M, Takahashi N, Fukuda A, Yayoi O, et al. Contribution of intragenic DNA methylation in mouse gametic DNA methylomes to establish oocyte-specific heritable marks. PLoS Genet. 2012;8:e1002440. doi: 10.1371/journal.pgen.1002440.
    • (2012) PLoS Genet. , vol.8 , pp. e1002440
    • Kobayashi, H.1    Sakurai, T.2    Imai, M.3    Takahashi, N.4    Fukuda, A.5    Yayoi, O.6
  • 6
    • 84859910536 scopus 로고    scopus 로고
    • A unique regulatory phase of DNA methylation in the early mammalian embryo
    • Smith ZD, Chan MM, Mikkelsen TS, Gu H, Gnirke A, Regev A, et al. A unique regulatory phase of DNA methylation in the early mammalian embryo. Nature. 2012;484:339-44.
    • (2012) Nature. , vol.484 , pp. 339-344
    • Smith, Z.D.1    Chan, M.M.2    Mikkelsen, T.S.3    Gu, H.4    Gnirke, A.5    Regev, A.6
  • 7
    • 84900300766 scopus 로고    scopus 로고
    • Programming and inheritance of parental DNA methylomes in mammals
    • Wang L, Zhang J, Duan J, Gao X, Zhu W, Lu X, et al. Programming and inheritance of parental DNA methylomes in mammals. Cell. 2014;157:979-91.
    • (2014) Cell. , vol.157 , pp. 979-991
    • Wang, L.1    Zhang, J.2    Duan, J.3    Gao, X.4    Zhu, W.5    Lu, X.6
  • 8
    • 78649459828 scopus 로고    scopus 로고
    • Targets and dynamics of promoter DNA methylation during early mouse development
    • Borgel J, Borgel J, Guibert S, Guibert S, Li Y, Li Y, et al. Targets and dynamics of promoter DNA methylation during early mouse development. Nat Genet. 2010;42:1093-100.
    • (2010) Nat Genet. , vol.42 , pp. 1093-1100
    • Borgel, J.1    Borgel, J.2    Guibert, S.3    Guibert, S.4    Li, Y.5    Li, Y.6
  • 9
    • 84866862172 scopus 로고    scopus 로고
    • Protection against de novo methylation is instrumental in maintaining parent-of-origin methylation inherited from the gametes
    • Proudhon C, Duffié R, Ajjan S, Cowley M, Iranzo J, Carbajosa G, et al. Protection against de novo methylation is instrumental in maintaining parent-of-origin methylation inherited from the gametes. Mol Cell. 2012;47:909-20.
    • (2012) Mol Cell. , vol.47 , pp. 909-920
    • Proudhon, C.1    Duffié, R.2    Ajjan, S.3    Cowley, M.4    Iranzo, J.5    Carbajosa, G.6
  • 10
    • 84898892512 scopus 로고    scopus 로고
    • DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos
    • Messerschmidt DM, Knowles BB, Solter D. DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos. Genes Dev. 2014;28:812-28.
    • (2014) Genes Dev. , vol.28 , pp. 812-828
    • Messerschmidt, D.M.1    Knowles, B.B.2    Solter, D.3
  • 11
    • 58149506281 scopus 로고    scopus 로고
    • Transcription is required for establishment of germline methylation marks at imprinted genes
    • Chotalia M, Smallwood SA, Ruf N, Dawson C, Lucifero D, Frontera M, et al. Transcription is required for establishment of germline methylation marks at imprinted genes. Genes Dev. 2009;23:105-17.
    • (2009) Genes Dev. , vol.23 , pp. 105-117
    • Chotalia, M.1    Smallwood, S.A.2    Ruf, N.3    Dawson, C.4    Lucifero, D.5    Frontera, M.6
  • 12
    • 77952701277 scopus 로고    scopus 로고
    • Targeted deletion of the Nesp55 DMR defines another Gnas imprinting control region and provides a mouse model of autosomal dominant PHP-Ib
    • Fröhlich LF, Mrakovcic M, Steinborn R, Chung U-I, Bastepe M, Jüppner H. Targeted deletion of the Nesp55 DMR defines another Gnas imprinting control region and provides a mouse model of autosomal dominant PHP-Ib. Proc Natl Acad Sci U S A. 2010;107:9275-80.
    • (2010) Proc Natl Acad Sci U S A. , vol.107 , pp. 9275-9280
    • Fröhlich, L.F.1    Mrakovcic, M.2    Steinborn, R.3    Chung, U.-I.4    Bastepe, M.5    Jüppner, H.6
  • 13
    • 84855273820 scopus 로고    scopus 로고
    • Transcription is required to establish maternal imprinting at the Prader-Willi syndrome and Angelman syndrome locus
    • Smith EY, Futtner CR, Chamberlain SJ, Johnstone KA, Resnick JL. Transcription is required to establish maternal imprinting at the Prader-Willi syndrome and Angelman syndrome locus. PLoS Genet. 2011;7:e1002422.
    • (2011) PLoS Genet. , vol.7 , pp. e1002422
    • Smith, E.Y.1    Futtner, C.R.2    Chamberlain, S.J.3    Johnstone, K.A.4    Resnick, J.L.5
  • 14
    • 77956193814 scopus 로고    scopus 로고
    • The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylation
    • Dhayalan A, Rajavelu A, Rathert P, Tamas R, Jurkowska RZ, Ragozin S, et al. The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylation. J Biol Chem. 2010;285:26114-20.
    • (2010) J Biol Chem. , vol.285 , pp. 26114-26120
    • Dhayalan, A.1    Rajavelu, A.2    Rathert, P.3    Tamas, R.4    Jurkowska, R.Z.5    Ragozin, S.6
  • 15
    • 77954126183 scopus 로고    scopus 로고
    • Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail
    • Zhang Y, Jurkowska R, Soeroes S, Rajavelu A, Dhayalan A, Bock I, et al. Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail. Nucleic Acids Res. 2010;38:4246-53.
    • (2010) Nucleic Acids Res. , vol.38 , pp. 4246-4253
    • Zhang, Y.1    Jurkowska, R.2    Soeroes, S.3    Rajavelu, A.4    Dhayalan, A.5    Bock, I.6
  • 16
    • 84890723656 scopus 로고    scopus 로고
    • Inferring the choreography of parental genomes during fertilization from ultralarge-scale whole-transcriptome analysis
    • Park S-J, Komata M, Inoue F, Yamada K, Nakai K, Ohsugi M, et al. Inferring the choreography of parental genomes during fertilization from ultralarge-scale whole-transcriptome analysis. Genes Dev. 2013;27:2736-48.
    • (2013) Genes Dev. , vol.27 , pp. 2736-2748
    • Park, S.-J.1    Komata, M.2    Inoue, F.3    Yamada, K.4    Nakai, K.5    Ohsugi, M.6
  • 17
    • 84863458292 scopus 로고    scopus 로고
    • Embryonic stem cell potency fluctuates with endogenous retrovirus activity
    • Macfarlan TS, Gifford WD, Driscoll S, Lettieri K, Rowe HM, Bonanomi D, et al. Embryonic stem cell potency fluctuates with endogenous retrovirus activity. Nature. 2012;487:57-63. doi: 10.1038/nature11244.
    • (2012) Nature. , vol.487 , pp. 57-63
    • Macfarlan, T.S.1    Gifford, W.D.2    Driscoll, S.3    Lettieri, K.4    Rowe, H.M.5    Bonanomi, D.6
  • 18
    • 79959567069 scopus 로고    scopus 로고
    • Deterministic and stochastic allele specific gene expression in single mouse blastomeres
    • Tang F, Barbacioru C, Nordman E, Bao S, Lee C, Wang X, et al. Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6:e21208. doi: 10.1371/journal.pone.0021208.
    • (2011) PLoS One. , vol.6 , pp. e21208
    • Tang, F.1    Barbacioru, C.2    Nordman, E.3    Bao, S.4    Lee, C.5    Wang, X.6
  • 19
    • 77952148742 scopus 로고    scopus 로고
    • Ab initio reconstruction of cell type-specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs
    • Guttman M, Garber M, Levin JZ, Donaghey J, Robinson J, Adiconis X, et al. Ab initio reconstruction of cell type-specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs. Nat Biotechnol. 2010;28:503-10.
    • (2010) Nat Biotechnol. , vol.28 , pp. 503-510
    • Guttman, M.1    Garber, M.2    Levin, J.Z.3    Donaghey, J.4    Robinson, J.5    Adiconis, X.6
  • 20
    • 84864880991 scopus 로고    scopus 로고
    • Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells
    • Ramsköld D, Luo S, Wang Y-C, Li R, Deng Q, Faridani OR, et al. Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells. Nat Biotechnol. 2012;30:777-82.
    • (2012) Nat Biotechnol. , vol.30 , pp. 777-782
    • Ramsköld, D.1    Luo, S.2    Wang, Y.-C.3    Li, R.4    Deng, Q.5    Faridani, O.R.6
  • 21
    • 84883134780 scopus 로고    scopus 로고
    • Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing
    • Xue Z, Huang K, Cai C, Cai L, Jiang C-Y, Feng Y, et al. Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing. Nature. 2013;500:593-7.
    • (2013) Nature. , vol.500 , pp. 593-597
    • Xue, Z.1    Huang, K.2    Cai, C.3    Cai, L.4    Jiang, C.-Y.5    Feng, Y.6
  • 22
    • 84865727393 scopus 로고    scopus 로고
    • The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression
    • Derrien T, Johnson R, Bussotti G, Tanzer A, Djebali S, Tilgner H, et al. The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. Genome Res. 2012;22:1775-89.
    • (2012) Genome Res. , vol.22 , pp. 1775-1789
    • Derrien, T.1    Johnson, R.2    Bussotti, G.3    Tanzer, A.4    Djebali, S.5    Tilgner, H.6
  • 23
    • 77952123055 scopus 로고    scopus 로고
    • Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
    • Trapnell C, Williams BA, Pertea G, Mortazavi A, Kwan G, van Baren MJ, et al. Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat Biotechnol. 2010;28:511-5.
    • (2010) Nat Biotechnol. , vol.28 , pp. 511-515
    • Trapnell, C.1    Williams, B.A.2    Pertea, G.3    Mortazavi, A.4    Kwan, G.5    Baren, M.J.6
  • 24
    • 84859885816 scopus 로고    scopus 로고
    • Differential gene and transcript expression analysis of RNA-Seq experiments with TopHat and Cufflinks
    • Trapnell C, Roberts A, Goff L, Pertea G, Kim D, Kelley DR, et al. Differential gene and transcript expression analysis of RNA-Seq experiments with TopHat and Cufflinks. Nat Protoc. 2012;7:562-78.
    • (2012) Nat Protoc. , vol.7 , pp. 562-578
    • Trapnell, C.1    Roberts, A.2    Goff, L.3    Pertea, G.4    Kim, D.5    Kelley, D.R.6
  • 25
    • 80051941094 scopus 로고    scopus 로고
    • Identification of novel transcripts in annotated genomes using RNA-Seq
    • Roberts A, Pimentel H, Trapnell C, Pachter L. Identification of novel transcripts in annotated genomes using RNA-Seq. Bioinformatics. 2011;27:2325-9.
    • (2011) Bioinformatics. , vol.27 , pp. 2325-2329
    • Roberts, A.1    Pimentel, H.2    Trapnell, C.3    Pachter, L.4
  • 26
    • 84867055719 scopus 로고    scopus 로고
    • Evaluation of different reference based annotation strategies using RNA-Seq - a case study in Drososphila pseudoobscura
    • Palmieri N, Nolte V, Suvorov A, Kosiol C, Schlötterer C. Evaluation of different reference based annotation strategies using RNA-Seq - a case study in Drososphila pseudoobscura. PLoS One. 2012;7:e46415.
    • (2012) PLoS One. , vol.7 , pp. e46415
    • Palmieri, N.1    Nolte, V.2    Suvorov, A.3    Kosiol, C.4    Schlötterer, C.5
  • 27
    • 84891798006 scopus 로고    scopus 로고
    • NONCODEv4: exploring the world of long non-coding RNA genes
    • Xie C, Yuan J, Li H, Li M, Zhao G, Bu D, et al. NONCODEv4: exploring the world of long non-coding RNA genes. Nucleic Acids Res. 2014;42:D98-D103.
    • (2014) Nucleic Acids Res. , vol.42 , pp. D98-D103
    • Xie, C.1    Yuan, J.2    Li, H.3    Li, M.4    Zhao, G.5    Bu, D.6
  • 28
    • 34547582418 scopus 로고    scopus 로고
    • CPC: assess the protein-coding potential of transcripts using sequence features and support vector machine
    • Kong L, Zhang Y, Ye Z-Q, Liu X-Q, Zhao S-Q, Wei L, et al. CPC: assess the protein-coding potential of transcripts using sequence features and support vector machine. Nucleic Acids Res. 2007;35:W345-9.
    • (2007) Nucleic Acids Res. , vol.35 , pp. W345-W349
    • Kong, L.1    Zhang, Y.2    Ye, Z.-Q.3    Liu, X.-Q.4    Zhao, S.-Q.5    Wei, L.6
  • 29
    • 84884915826 scopus 로고    scopus 로고
    • Utilizing sequence intrinsic composition to classify protein-coding and long non-coding transcripts
    • Sun L, Luo H, Bu D, Zhao G, Yu K, Zhang C, et al. Utilizing sequence intrinsic composition to classify protein-coding and long non-coding transcripts. Nucleic Acids Res. 2013;41:e166-6.
    • (2013) Nucleic Acids Res. , vol.41 , pp. e166-e176
    • Sun, L.1    Luo, H.2    Bu, D.3    Zhao, G.4    Yu, K.5    Zhang, C.6
  • 31
    • 78649715690 scopus 로고    scopus 로고
    • Hormad1 mutation disrupts synaptonemal complex formation, recombination, and chromosome segregation in mammalian meiosis
    • Shin Y-H, Choi Y, Erdin SU, Yatsenko SA, Kloc M, Yang F, et al. Hormad1 mutation disrupts synaptonemal complex formation, recombination, and chromosome segregation in mammalian meiosis. PLoS Genet. 2010;6:e1001190.
    • (2010) PLoS Genet. , vol.6 , pp. e1001190
    • Shin, Y.-H.1    Choi, Y.2    Erdin, S.U.3    Yatsenko, S.A.4    Kloc, M.5    Yang, F.6
  • 32
    • 84887865235 scopus 로고    scopus 로고
    • A retrotransposon-driven dicer isoform directs endogenous small interfering RNA production in mouse oocytes
    • Flemr M, Malik R, Franke V, Nejepinska J, Sedlacek R, Vlahovicek K, et al. A retrotransposon-driven dicer isoform directs endogenous small interfering RNA production in mouse oocytes. Cell. 2013;155:807-16.
    • (2013) Cell. , vol.155 , pp. 807-816
    • Flemr, M.1    Malik, R.2    Franke, V.3    Nejepinska, J.4    Sedlacek, R.5    Vlahovicek, K.6
  • 34
    • 84875226981 scopus 로고    scopus 로고
    • Chromatin signatures and retrotransposon profiling in mouse embryos reveal regulation of LINE-1 by RNA
    • Fadloun A, Le Gras S, Jost B, Ziegler-Birling C, Takahashi H, Gorab E, et al. Chromatin signatures and retrotransposon profiling in mouse embryos reveal regulation of LINE-1 by RNA. Nat Struct Mol Biol. 2013;20:332-8.
    • (2013) Nat Struct Mol Biol. , vol.20 , pp. 332-338
    • Fadloun, A.1    Gras, S.2    Jost, B.3    Ziegler-Birling, C.4    Takahashi, H.5    Gorab, E.6
  • 35
    • 84876820776 scopus 로고    scopus 로고
    • Mouse oocyte methylomes at base resolution reveal genome-wide accumulation of non-CpG methylation and role of DNA methyltransferases
    • Shirane K, Toh H, Kobayashi H, Miura F, Chiba H, Ito T, et al. Mouse oocyte methylomes at base resolution reveal genome-wide accumulation of non-CpG methylation and role of DNA methyltransferases. PLoS Genet. 2013;9:e1003439.
    • (2013) PLoS Genet. , vol.9 , pp. e1003439
    • Shirane, K.1    Toh, H.2    Kobayashi, H.3    Miura, F.4    Chiba, H.5    Ito, T.6
  • 37
    • 34249874030 scopus 로고    scopus 로고
    • Infrequently transcribed long genes depend on the Set2/Rpd3S pathway for accurate transcription
    • Li B, Gogol M, Carey M, Pattenden SG, Seidel C, Workman JL. Infrequently transcribed long genes depend on the Set2/Rpd3S pathway for accurate transcription. Genes Dev. 2007;21:1422-30.
    • (2007) Genes Dev. , vol.21 , pp. 1422-1430
    • Li, B.1    Gogol, M.2    Carey, M.3    Pattenden, S.G.4    Seidel, C.5    Workman, J.L.6
  • 38
    • 84864752375 scopus 로고    scopus 로고
    • Cfp1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cells
    • Clouaire T, Webb S, Skene P, Illingworth R, Kerr A, Andrews R, et al. Cfp1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cells. Genes Dev. 2012;26:1714-28.
    • (2012) Genes Dev. , vol.26 , pp. 1714-1728
    • Clouaire, T.1    Webb, S.2    Skene, P.3    Illingworth, R.4    Kerr, A.5    Andrews, R.6
  • 39
    • 84355163093 scopus 로고    scopus 로고
    • DNA-binding factors shape the mouse methylome at distal regulatory regions
    • Stadler MB, Murr R, Burger L, Ivanek R, Lienert F, Schöler A, et al. DNA-binding factors shape the mouse methylome at distal regulatory regions. Nature. 2011;480:490-5. doi: 10.1038/nature10716.
    • (2011) Nature. , vol.480 , pp. 490-495
    • Stadler, M.B.1    Murr, R.2    Burger, L.3    Ivanek, R.4    Lienert, F.5    Schöler, A.6
  • 40
    • 84876482998 scopus 로고    scopus 로고
    • Clinical presentation of 6q24 transient neonatal diabetes mellitus (6q24 TNDM) and genotype-phenotype correlation in an international cohort of patients
    • Docherty LE, Kabwama S, Lehmann A, Hawke E, Harrison L, Flanagan SE, et al. Clinical presentation of 6q24 transient neonatal diabetes mellitus (6q24 TNDM) and genotype-phenotype correlation in an international cohort of patients. Diabetologia. 2013;56:758-62.
    • (2013) Diabetologia. , vol.56 , pp. 758-762
    • Docherty, L.E.1    Kabwama, S.2    Lehmann, A.3    Hawke, E.4    Harrison, L.5    Flanagan, S.E.6
  • 41
    • 84996559063 scopus 로고    scopus 로고
    • Ontogeny of CpG island methylation and specificity of DNMT3 methyltransferases during embryonic development in the mouse
    • Auclair G, Guibert S, Bender A, Weber M. Ontogeny of CpG island methylation and specificity of DNMT3 methyltransferases during embryonic development in the mouse. Genome Biol. 2014;15:545.
    • (2014) Genome Biol. , vol.15 , pp. 545
    • Auclair, G.1    Guibert, S.2    Bender, A.3    Weber, M.4
  • 42
    • 69449092535 scopus 로고    scopus 로고
    • Histone methylation is mechanistically linked to DNA methylation at imprinting control regions in mammals
    • Henckel A, Nakabayashi K, Sanz LA, Feil R, Hata K, Arnaud P. Histone methylation is mechanistically linked to DNA methylation at imprinting control regions in mammals. Hum Mol Genet. 2009;18:3375-83.
    • (2009) Hum Mol Genet. , vol.18 , pp. 3375-3383
    • Henckel, A.1    Nakabayashi, K.2    Sanz, L.A.3    Feil, R.4    Hata, K.5    Arnaud, P.6
  • 43
    • 70349272130 scopus 로고    scopus 로고
    • KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints
    • Ciccone DN, Su H, Hevi S, Gay F, Lei H, Bajko J, et al. KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints. Nature. 2009;461:415-8.
    • (2009) Nature. , vol.461 , pp. 415-418
    • Ciccone, D.N.1    Su, H.2    Hevi, S.3    Gay, F.4    Lei, H.5    Bajko, J.6
  • 44
    • 61449161294 scopus 로고    scopus 로고
    • Fast genomic μChIP-chip from 1,000 cells
    • Dahl JA, Reiner AH, Collas P. Fast genomic μChIP-chip from 1,000 cells. Genome Biol. 2009;10:R13.
    • (2009) Genome Biol. , vol.10 , pp. R13
    • Dahl, J.A.1    Reiner, A.H.2    Collas, P.3
  • 45
    • 77955497653 scopus 로고    scopus 로고
    • Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation
    • Fang R, Barbera AJ, Xu Y, Rutenberg M, Leonor T, Bi Q, et al. Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation. Mol Cell. 2010;39:222-33.
    • (2010) Mol Cell. , vol.39 , pp. 222-233
    • Fang, R.1    Barbera, A.J.2    Xu, Y.3    Rutenberg, M.4    Leonor, T.5    Bi, Q.6
  • 46
    • 84923330509 scopus 로고    scopus 로고
    • Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation
    • Baubec T, Colombo DF, Wirbelauer C, Schmidt J, Burger L, Krebs AR, et al. Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation. Nature. 2015;520:243-7.
    • (2015) Nature. , vol.520 , pp. 243-247
    • Baubec, T.1    Colombo, D.F.2    Wirbelauer, C.3    Schmidt, J.4    Burger, L.5    Krebs, A.R.6
  • 47
    • 84907997839 scopus 로고    scopus 로고
    • Gene body methylation can alter gene expression and is a therapeutic target in cancer
    • Yang X, Han H, De Carvalho DD, Lay FD, Jones PA, Liang G. Gene body methylation can alter gene expression and is a therapeutic target in cancer. Cancer Cell. 2014;26:577-90.
    • (2014) Cancer Cell. , vol.26 , pp. 577-590
    • Yang, X.1    Han, H.2    Carvalho, D.D.3    Lay, F.D.4    Jones, P.A.5    Liang, G.6
  • 48
    • 79957868920 scopus 로고    scopus 로고
    • Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications
    • Krueger F, Andrews SR. Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications. Bioinformatics. 2011;27:1571-2.
    • (2011) Bioinformatics. , vol.27 , pp. 1571-1572
    • Krueger, F.1    Andrews, S.R.2
  • 50
    • 79951529848 scopus 로고    scopus 로고
    • Dynamic stage-specific changes in imprinted differentially methylated regions during early mammalian development and prevalence of non-CpG methylation in oocytes
    • Tomizawa S-I, Kobayashi H, Watanabe T, Andrews S, Hata K, Kelsey G, et al. Dynamic stage-specific changes in imprinted differentially methylated regions during early mammalian development and prevalence of non-CpG methylation in oocytes. Development. 2011;138:811-20.
    • (2011) Development. , vol.138 , pp. 811-820
    • Tomizawa, S.-I.1    Kobayashi, H.2    Watanabe, T.3    Andrews, S.4    Hata, K.5    Kelsey, G.6


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