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Volumn 75, Issue 7, 2015, Pages 1495-1503

Phosphotyrosine signaling analysis in human tumors is confounded by systemic ischemia-driven artifacts and intra-specimen heterogeneity

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHOTYROSINE;

EID: 84942301905     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-14-2309     Document Type: Article
Times cited : (42)

References (42)
  • 1
    • 0028838971 scopus 로고
    • Protein kinases and phosphatases: The yin and yang of protein phosphorylation and signaling
    • Hunter T. Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling. Cell 1995;80:225-36.
    • (1995) Cell , vol.80 , pp. 225-236
    • Hunter, T.1
  • 3
    • 77953292595 scopus 로고    scopus 로고
    • Post-translational modifications in signal integration
    • Deribe YL, Pawson T, Dikic I. Post-translational modifications in signal integration. Nat Struct Mol Biol 2010;17:666-72.
    • (2010) Nat Struct Mol Biol , vol.17 , pp. 666-672
    • Deribe, Y.L.1    Pawson, T.2    Dikic, I.3
  • 4
    • 0000109995 scopus 로고
    • Transforming gene product of rous sarcoma virus phosphorylates tyrosine
    • Hunter T, Sefton BM. Transforming gene product of Rous sarcoma virus phosphorylates tyrosine. Proc Natl Acad Sci U S A 1980;77:1311-5.
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 1311-1315
    • Hunter, T.1    Sefton, B.M.2
  • 7
    • 84877028141 scopus 로고    scopus 로고
    • Comprehensive molecular portraits of human breast tumours
    • Cancer Genome Atlas Network. Comprehensive molecular portraits of human breast tumours. Nature 2012;490:61-70.
    • (2012) Nature , vol.490 , pp. 61-70
  • 8
    • 84897022815 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of urothelial bladder carcinoma
    • Cancer Genome Atlas Research Network. Comprehensive molecular characterization of urothelial bladder carcinoma. Nature 2014;507:315-22.
    • (2014) Nature , vol.507 , pp. 315-322
  • 9
    • 84885647278 scopus 로고    scopus 로고
    • Connecting genomic alterations to cancer biology with proteomics: The NCI clinical proteomic tumor analysis consortium
    • Ellis MJ, Gillette M, Carr SA, Paulovich AG, Smith RD, Rodland KK, et al. Connecting genomic alterations to cancer biology with proteomics: the NCI Clinical Proteomic Tumor Analysis Consortium. Cancer Discov 2013;3:1108-12.
    • (2013) Cancer Discov , vol.3 , pp. 1108-1112
    • Ellis, M.J.1    Gillette, M.2    Carr, S.A.3    Paulovich, A.G.4    Smith, R.D.5    Rodland, K.K.6
  • 10
    • 84855572697 scopus 로고    scopus 로고
    • Mapping in vivo signal transduction defects by phosphoproteomics
    • Stasyk T, Huber LA. Mapping in vivo signal transduction defects by phosphoproteomics. Trends Mol Med 2012;18:43-51.
    • (2012) Trends Mol Med , vol.18 , pp. 43-51
    • Stasyk, T.1    Huber, L.A.2
  • 11
    • 84868493819 scopus 로고    scopus 로고
    • Toward quantitative phosphotyrosine profiling in vivo
    • Johnson H, White FM. Toward quantitative phosphotyrosine profiling in vivo. Semin Cell Dev Biol 2012;23:854-62.
    • (2012) Semin Cell Dev Biol , vol.23 , pp. 854-862
    • Johnson, H.1    White, F.M.2
  • 12
    • 84871297843 scopus 로고    scopus 로고
    • Next-generation proteomics: Towards an integrative view of proteome dynamics
    • Altelaar AFM, Munoz J, Heck AJR. Next-generation proteomics: towards an integrative view of proteome dynamics. Nat Rev Genet 2013;14:35-48.
    • (2013) Nat Rev Genet , vol.14 , pp. 35-48
    • Altelaar, A.F.M.1    Munoz, J.2    Heck, A.J.R.3
  • 13
    • 55049089416 scopus 로고    scopus 로고
    • A portrait of tissue phosphoprotein stability in the clinical tissue procurement process
    • Espina V, Edmiston KH, Heiby M, Pierobon M, Sciro M, Merritt B, et al. A portrait of tissue phosphoprotein stability in the clinical tissue procurement process. Mol Cell Proteomics 2008;7:1998-2018.
    • (2008) Mol Cell Proteomics , vol.7 , pp. 1998-2018
    • Espina, V.1    Edmiston, K.H.2    Heiby, M.3    Pierobon, M.4    Sciro, M.5    Merritt, B.6
  • 15
    • 0017704436 scopus 로고
    • Metastasis results from preexisting variant cells within a malignant tumor
    • Fidler IJ, Kripke ML. Metastasis results from preexisting variant cells within a malignant tumor. Science 1977;197:893-5.
    • (1977) Science , vol.197 , pp. 893-895
    • Fidler, I.J.1    Kripke, M.L.2
  • 16
    • 84875884456 scopus 로고    scopus 로고
    • Cellular heterogeneity and molecular evolution in cancer
    • Almendro V, Marusyk A, Polyak K. Cellular heterogeneity and molecular evolution in cancer. Annu Rev Pathol 2013;8:277-302.
    • (2013) Annu Rev Pathol , vol.8 , pp. 277-302
    • Almendro, V.1    Marusyk, A.2    Polyak, K.3
  • 18
    • 84884368877 scopus 로고    scopus 로고
    • Influence of tumour micro-environment heterogeneity on therapeutic response
    • Junttila MR, de Sauvage FJ. Influence of tumour micro-environment heterogeneity on therapeutic response. Nature 2013;501:346-54.
    • (2013) Nature , vol.501 , pp. 346-354
    • Junttila, M.R.1    De Sauvage, F.J.2
  • 19
    • 84889677377 scopus 로고    scopus 로고
    • Metastatic castration-resistant prostate cancer reveals intrapatient similarity and interpatient heterogeneity of therapeutic kinase targets
    • Drake JM, Graham NA, Lee JK, Stoyanova T, Faltermeier CM, Sud S, et al. Metastatic castration-resistant prostate cancer reveals intrapatient similarity and interpatient heterogeneity of therapeutic kinase targets. Proc Natl Acad Sci U S A 2013;110:E4762-9.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. E4762-E4769
    • Drake, J.M.1    Graham, N.A.2    Lee, J.K.3    Stoyanova, T.4    Faltermeier, C.M.5    Sud, S.6
  • 21
    • 84904111890 scopus 로고    scopus 로고
    • Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels
    • Mertins P, Yang F, Liu T, Mani DR, Petyuk VA, Gillette MA, et al. Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 2014;3:1690-704.
    • (2014) Mol Cell Proteomics , vol.3 , pp. 1690-1704
    • Mertins, P.1    Yang, F.2    Liu, T.3    Mani, D.R.4    Petyuk, V.A.5    Gillette, M.A.6
  • 23
    • 33847172327 scopus 로고    scopus 로고
    • Clustering by passing messages between data points
    • Frey BJ, Dueck D. Clustering by passing messages between data points. Science 2007;315:972-6.
    • (2007) Science , vol.315 , pp. 972-976
    • Frey, B.J.1    Dueck, D.2
  • 24
    • 61449203001 scopus 로고    scopus 로고
    • KEA: Kinase enrichment analysis
    • Lachmann A, Ma'ayan A. KEA: kinase enrichment analysis. Bioinformatics 2009;25:684-6.
    • (2009) Bioinformatics , vol.25 , pp. 684-686
    • Lachmann, A.1    Ma'Ayan, A.2
  • 26
    • 70849122697 scopus 로고    scopus 로고
    • Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations
    • Brennan C, Momota H, Hambardzumyan D, Ozawa T, Tandon A, Pedraza A, et al. Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations. PLoS ONE 2009;4:e7752.
    • (2009) PLoS ONE , vol.4
    • Brennan, C.1    Momota, H.2    Hambardzumyan, D.3    Ozawa, T.4    Tandon, A.5    Pedraza, A.6
  • 27
    • 77955059513 scopus 로고    scopus 로고
    • Mechanisms and functions of p38 MAPK signalling
    • Cuadrado A, Nebreda AR. Mechanisms and functions of p38 MAPK signalling. Biochem J 2010;429:403-17.
    • (2010) Biochem J , vol.429 , pp. 403-417
    • Cuadrado, A.1    Nebreda, A.R.2
  • 28
    • 0026777369 scopus 로고
    • A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction
    • Pelicci G, Lanfrancone L, Grignani F, McGlade J, Cavallo F, Forni G, et al. A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction. Cell 1992;70:93-104.
    • (1992) Cell , vol.70 , pp. 93-104
    • Pelicci, G.1    Lanfrancone, L.2    Grignani, F.3    McGlade, J.4    Cavallo, F.5    Forni, G.6
  • 30
  • 31
    • 77649114060 scopus 로고    scopus 로고
    • Eph receptors and ephrins in cancer: Bidirectional signalling and beyond
    • Pasquale EB. Eph receptors and ephrins in cancer: bidirectional signalling and beyond. Nat Rev Cancer 2010;10:165-80.
    • (2010) Nat Rev Cancer , vol.10 , pp. 165-180
    • Pasquale, E.B.1
  • 32
    • 3543079923 scopus 로고    scopus 로고
    • Epidermal growth factor modulates tyrosine phosphorylation of a novel tensin family member, tensin3
    • Cui Y, Liao Y-C, Lo SH. Epidermal growth factor modulates tyrosine phosphorylation of a novel tensin family member, tensin3. Mol Cancer Res 2004;2:225-32.
    • (2004) Mol Cancer Res , vol.2 , pp. 225-232
    • Cui, Y.1    Liao, Y.-C.2    Lo, S.H.3
  • 34
    • 9144253936 scopus 로고    scopus 로고
    • The ASK1-MAP kinase cascades in mammalian stress response
    • Matsukawa J, Matsuzawa A, Takeda K, Ichijo H. The ASK1-MAP kinase cascades in mammalian stress response. J Biochem 2004;136:261-5.
    • (2004) J Biochem , vol.136 , pp. 261-265
    • Matsukawa, J.1    Matsuzawa, A.2    Takeda, K.3    Ichijo, H.4
  • 36
    • 84875651465 scopus 로고    scopus 로고
    • The role of mitogen-activated protein kinase-activated protein kinases (MAPKAPKs) in inflammation
    • Moens U, Kostenko S, Sveinbjørnsson B. The role of mitogen-activated protein kinase-activated protein kinases (MAPKAPKs) in inflammation. Genes (Basel) 2013;4:101-33.
    • (2013) Genes (Basel) , vol.4 , pp. 101-133
    • Moens, U.1    Kostenko, S.2    Sveinbjørnsson, B.3
  • 37
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 38
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011;144:646-74.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 39
    • 77953565590 scopus 로고    scopus 로고
    • Phosphotyrosine signaling analysis of site-specific mutations on EGFRvIII identifies determinants governing glioblastoma cell growth
    • Huang PH, Miraldi ER, Xu AM, Kundukulam VA, del Rosario AM, Flynn RA, et al. Phosphotyrosine signaling analysis of site-specific mutations on EGFRvIII identifies determinants governing glioblastoma cell growth. Mol Biosyst 2010;6:1227-37.
    • (2010) Mol Biosyst , vol.6 , pp. 1227-1237
    • Huang, P.H.1    Miraldi, E.R.2    Xu, A.M.3    Kundukulam, V.A.4    Del Rosario, A.M.5    Flynn, R.A.6
  • 40
    • 42649125571 scopus 로고    scopus 로고
    • Differential effects of oncogenic K-ras and N-ras on proliferation, differentiation and tumor progression in the colon
    • Haigis KM, Kendall KR, Wang Y, Cheung A, Haigis MC, Glickman JN, et al. Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon. Nat Genet 2008; 40:600-8.
    • (2008) Nat Genet , vol.40 , pp. 600-608
    • Haigis, K.M.1    Kendall, K.R.2    Wang, Y.3    Cheung, A.4    Haigis, M.C.5    Glickman, J.N.6
  • 41
    • 14444288522 scopus 로고    scopus 로고
    • The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling
    • Huang HS, Nagane M, Klingbeil CK, Lin H, Nishikawa R, Ji XD, et al. The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling. J Biol Chem 1997;272:2927-35.
    • (1997) J Biol Chem , vol.272 , pp. 2927-2935
    • Huang, H.S.1    Nagane, M.2    Klingbeil, C.K.3    Lin, H.4    Nishikawa, R.5    Ji, X.D.6
  • 42
    • 84866122803 scopus 로고    scopus 로고
    • Navigating cancer network attractors for tumor-specific therapy
    • Creixell P, Schoof EM, Erler JT, Linding R. Navigating cancer network attractors for tumor-specific therapy. Nat Biotechnol 2012;30:842-8.
    • (2012) Nat Biotechnol , vol.30 , pp. 842-848
    • Creixell, P.1    Schoof, E.M.2    Erler, J.T.3    Linding, R.4


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