Delayed afterdepolarizations generate both triggers and a vulnerable substrate promoting reentry in cardiac tissue

Heart Rhythm

Volumn 12, Issue 10, 2015, Pages 2115-2124

  Liu, Michael B ^a,b   De Lange, Enno ^a,c   Garfinkel, Alan ^a,b   Weiss, James N ^a,b   Qu, Zhilin ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Arrhythmia; Computer simulation; Conduction block; Delayed after depolarization; Reentry

Indexed keywords

SODIUM CHANNEL; CALCIUM;

ARRHYTHMOGENESIS; ARTICLE; COMPUTER SIMULATION; CONTROLLED STUDY; DELAYED AFTERDEPOLARIZATION; DIFFUSION COEFFICIENT; EXTRASYSTOLE; GAP JUNCTION; HEART ARRHYTHMIA; HEART DEPOLARIZATION; HEART MUSCLE FIBER MEMBRANE POTENTIAL; HEART VENTRICLE CONTRACTION; NERVE BLOCK; PRIORITY JOURNAL; REENTRY ARRHYTHMIA; SODIUM CONDUCTANCE; ACTION POTENTIAL; CARDIAC MUSCLE CELL; HEART MUSCLE CONDUCTION SYSTEM; HUMAN; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; SARCOPLASMIC RETICULUM; SINOATRIAL NODAL REENTRY TACHYCARDIA; THEORETICAL MODEL;

ACTION POTENTIALS; ARRHYTHMIAS, CARDIAC; CALCIUM; COMPUTER SIMULATION; GAP JUNCTIONS; HEART CONDUCTION SYSTEM; HUMANS; MODELS, THEORETICAL; MYOCYTES, CARDIAC; SARCOPLASMIC RETICULUM; TACHYCARDIA, SINOATRIAL NODAL REENTRY;

EID: 84942295300     PISSN: 15475271     EISSN: 15563871     Source Type: Journal    
DOI: 10.1016/j.hrthm.2015.06.019     Document Type: Article

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