A mutation in the β3 subunit of the cardiac sodium channel associated with brugada ECG phenotype

Circulation: Cardiovascular Genetics

Volumn 2, Issue 3, 2009, Pages 270-278

  Hu, Dan ^a,f   Barajas Martinez, Hector ^a,f   Burashnikov, Elena ^a,f   Springer, Michael ^b,f   Wu, Yuesheng ^a,f   Varro, Andras ^d,e,f   Pfeiffer, Ryan ^a,f   Koopmann, Tamara T ^c,f   Cordeiro, Jonathan M ^a,f   Guerchicoff, Alejandra ^a,f   Pollevick, Guido D ^a,f   Antzelevitch, Charles ^a,f  

^a MASONIC MEDICAL RESEARCH LABORATORY   (United States)

^b Cardiology Department   (United States)

^c UNIVERSITY OF LOUISVILLE   (United States)

^d ACADEMIC MEDICAL CENTER   (Netherlands)

^e UNIVERSITY OF SZEGED   (Hungary)

^f INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

Arrhythmia; Brugada syndrome; Ion channels; Protein trafficking; SCN3B

Indexed keywords

GREEN FLUORESCENT PROTEIN; PROCAINAMIDE; SODIUM CHANNEL; SODIUM CHANNEL BETA3 SUBUNIT; SODIUM CHANNEL NAV1.5; SODIUM CHANNEL SCN1B; SODIUM CHANNEL SCN3B; UNCLASSIFIED DRUG; HYBRID PROTEIN; SCN3B PROTEIN, HUMAN;

ADULT; ARTICLE; BRUGADA SYNDROME; CELL ORGANELLE; CELL SURFACE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ELECTROCARDIOGRAM; EXON; GENE EXPRESSION; GENE SEQUENCE; GENETIC ASSOCIATION; HEART MUSCLE; HEART VENTRICLE; HUMAN; MAJOR CLINICAL STUDY; MALE; MISSENSE MUTATION; NUCLEOTIDE SEQUENCE; PATCH CLAMP; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; SODIUM CURRENT; ST SEGMENT ELEVATION; WESTERN BLOTTING; WILD TYPE; AMINO ACID SEQUENCE; CASE REPORT; CELL LINE; ELECTROCARDIOGRAPHY; GENETICS; METABOLISM; MIDDLE AGED; RADIOGRAPHY;

AMINO ACID SEQUENCE; BRUGADA SYNDROME; CELL LINE; ELECTROCARDIOGRAPHY; GREEN FLUORESCENT PROTEINS; HUMANS; MALE; MIDDLE AGED; MUTATION, MISSENSE; PATCH-CLAMP TECHNIQUES; PHENOTYPE; RECOMBINANT FUSION PROTEINS; SODIUM CHANNELS;

EID: 69549145477     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.108.829192     Document Type: Article

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