Topical application of propolis enhances cutaneous wound healing by promoting TGF-beta/smad-mediated collagen production in a streptozotocin-induced type I diabetic mouse model

Cellular Physiology and Biochemistry

Volumn 37, Issue 3, 2015, Pages 940-954

  Hozzein, Wael N ^a,b   Badr, Gamal ^c   Al Ghamdi, Ahmad A ^d   Sayed, Ayat ^e   Al Waili, Noori S ^f   Garraud, Olivier ^g,h  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b Beni Suef University   (Egypt)

^c Assiut University   (Egypt)

^d KING SAUD UNIVERSITY   (Saudi Arabia)

^e Assiut University Faculty of Medicine   (Egypt)

^f Al Waili's Charitable Foundation for Sciences and Trading   (United States)

^g INSTITUT NATIONAL DE LA TRANSFUSION SANGUINE   (France)

^h UNIVERSITÉ DE LYON   (France)

Author keywords

Cytokines; Diabetes mellitus; Inflammation; Propolis; Wound healing

Indexed keywords

COLLAGEN; GELATINASE B; INTERLEUKIN 1BETA; INTERLEUKIN 6; PROPOLIS; SMAD PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; STREPTOZOCIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; MMP9 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; INSULIN DEPENDENT DIABETES MELLITUS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SKIN INJURY; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; WOUND CLOSURE; WOUND HEALING; WOUND HEALING IMPAIRMENT; ANIMAL; CHEMICALLY INDUCED; DRUG ADMINISTRATION; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION REGULATION; HUMAN; METABOLISM; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; ANIMALS; COLLAGEN; CYTOKINES; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DRUG ADMINISTRATION SCHEDULE; GENE EXPRESSION REGULATION; HUMANS; MALE; MATRIX METALLOPROTEINASE 9; MICE; PROPOLIS; SMAD PROTEINS; STREPTOZOCIN; TRANSFORMING GROWTH FACTOR BETA; WOUND HEALING;

EID: 84942279422     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000430221     Document Type: Article

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