Understanding the role of immune regulation in wound healing

American Journal of Surgery

Volumn 187, Issue 5 SUPPL. 1, 2004, Pages S11-S16

  Park, Julie E ^a   Barbul, Adrian ^a  

^a DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; CYTOKINE; GROWTH FACTOR; INTERLEUKIN 1; INTERLEUKIN 6; LYMPHOKINE; PLATELET DERIVED GROWTH FACTOR; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

B LYMPHOCYTE; CELL MIGRATION; CELL PROLIFERATION; COLLAGEN SYNTHESIS; CROSS LINKING; CYTOKINE RELEASE; FIBROBLAST; HISTOLOGY; HOST RESISTANCE; HUMAN; IMMUNE SYSTEM; IMMUNOCOMPETENT CELL; IMMUNOREGULATION; INFLAMMATION; LYMPHOCYTE; MACROPHAGE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; REVIEW; SKIN BIOPSY; T LYMPHOCYTE; THYMECTOMY; WOUND HEALING;

EID: 2442595111     PISSN: 00029610     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9610(03)00296-4     Document Type: Article

References (46)

1. Witte M.B., Barbul A. General principles of wound healing. Surg Clin North Am. 77:1997;509-528
2. Simpson D.M., Ross R. The neutrophilic leukocyte in wound repair a study with antineutrophil serum. J Clin Invest. 51:1972;2009-2023
3. Canturk N.Z., Esen N., Vural B., et al. The relationship between neutrophils and incisional wound healing. Skin Pharmacol Appl Skin Physiol. 14:2001;108-116
4. Leibovich S.J., Ross R. The role of the macrophage in wound repair a study with hydrocortisone and antimacrophage serum. Am J Pathol. 78:1975;71-100
5. Regan M.C. The Role of Immune Mononuclear Cells in the Regulation of Fibroblast Activity During Wound Healing. thesis:1992;University of Dublin, Dublin
6. Clark R.A., Stone R.D., Leung D.Y., Silver I., Hohn D.C., Hunt T.K. Role of macrophages in wound healing. Surg Forum. 27:1976;16-18
7. Casey W.J., Peacock E.E. Jr, Chvapil M. Induction of collagen synthesis in rats by transplantation of allogenic macrophages. Surg Forum. 27:1976;53-55
8. Wahl SM. Host immune factors regulating fibrosis. In: Evered D, Whelan J, eds. Fibrosis. Ciba Foundation Symposium Series, No. 114. London: Pitman, 1985:175-195
9. Barbul A. Immune aspects of wound repair. Clin Plast Surg. 17:1990;433-442
10. Kovacs E.J., DiPietro L.A. Fibrogenic cytokines and connective tissue production. FASEB J. 8:1994;854-861
11. Wei L.H., Kuo M.L., Chen C.A., et al. Interleukin-6 in cervical cancer the relationship with vascular endothelial growth factor. Gynecol Oncol. 82:2001;49-56
12. Wang Z., Castresana M.R., Newman W.H. Reactive oxygen and NF-kappaB in VEGF-induced migration of human vascular smooth muscle cells. Biochem Biophys Res Commun. 285:2001;669-674
13. Roesel J.F., Nanney L.B. Assessment of differential cytokine effects on angiogenesis using an in vivo model of cutaneous wound repair. J Surg Res. 58:1995;449-459
14. Gallucci R.M., Sugawara T., Yucesoy B., et al. Interleukin-6 treatment augments cutaneous wound healing in immunosuppressed mice. J Interferon Cytokine Res. 21:2001;603-609
15. Malecaze F., Simorre V., Chollet P., et al. Interleukin-6 in tear fluid after photorefractive keratectomy and its effects on keratocytes in culture. Cornea. 16:1997;580-587
16. Hankenson K.D., Watkins B.A., Schoenlein I.A., Allen K.G., Turek J.J. Omega-3 fatty acids enhance ligament fibroblast collagen formation in association with changes in interleukin-6 production. Proc Soc Exp Biol Med. 223:2000;88-95
17. Duncan M.R., Berman B. Differential regulation of collagen, glycosaminoglycan, fibronectin, and collagenase activity production in cultured human adult dermal fibroblasts by interleukin 1-alpha and beta and tumor necrosis factor-alpha and beta. J Invest Dermatol. 92:1989;699-706
18. Schaffer M.R., Tantry U., van Wesep R.A., Barbul A. Nitric oxide metabolism in wounds. J Surg Res. 71:1997;25-31
19. Reichner J.S., Meszaros A.J., Louis C.A., et al. Molecular and metabolic evidence for the restricted expression of inducible nitric oxide synthase in healing wounds. Am J Pathol. 154:1999;1097-1104
20. Lee R.H., Efron D., Tantry U., Barbul A. Nitric oxide in the healing wound a time-course study. J Surg Res. 101:2001;104-108
21. Efron D.T., Most D., Barbul A. Role of nitric oxide in wound healing. Curr Opin Clin Nutr Metab Care. 3:2000;197-204
22. Stallmeyer B., Kampfer H., Kolb N., Pfeilschifter J., Frank S. The function of nitric oxide in wound repair inhibition of inducible nitric oxide-synthase severely impairs wound reepithelialization. J Invest Dermatol. 113:1999;1090-1098
23. Yamasaki K., Edington H.D., McClosky C., et al. Reversal of impaired wound repair in iNOS-deficient mice by topical adenoviral-mediated iNOS gene transfer. J Clin Invest. 101:1998;967-971
24. Schaffer M.R., Tantry U., Thornton F.J., Barbul A. Inhibition of nitric oxide synthesis in wounds pharmacology and effect on accumulation of collagen in wounds in mice. Eur J Surg. 165:1999;262-267
25. Efron D.T., Most D., Shi H.P., Tantry U.S., Barbul A. A novel method of studying wound healing. J Surg Res. 98:2001;16-20
26. Shi H.P., Most D., Efron D.T., Tantry U., Fischel M.H., Barbul A. The role of iNOS in wound healing. Surgery. 130:2001;225-229
27. Leibovich S.J., Polverini P.J., Fong T.W., Harlow L.A., Koch A.E. Production of angiogenic activity by human monocytes requires an L-arginine/nitric oxide-synthase-dependent effector mechanism. Proc Natl Acad Sci U S A. 91:1994;4190-4194
28. Fishel R.S., Barbul A., Beschorner W.E., Wasserkrug H.L., Efron G. Lymphocyte participation in wound healing morphologic assessment using monoclonal antibodies. Ann Surg. 206:1987;25-29
29. Barbul A. Role of T-cell-dependent immune system in wound healing. Prog Clin Biol Res. 266:1988;161-175
30. Barbul A., Sisto D., Rettura G., Levenson S.M., Seifter E., Efron G. Thymic inhibition of wound healing abrogation by adult thymectomy. J Surg Res. 32:1982;338-342
31. Barbul A., Shawe T., Frankel H.L., Efron J.E., Wasserkrug H.L. Inhibition of wound repair by thymic hormones. Surgery. 106:1989;373-377
32. Barbul A., Shawe T., Rotter S.M., Efron J.E., Wasserkrug H.L., Badawy S.B. Wound healing in nude mice a study on the regulatory role of lymphocytes in fibroplasia. Surgery. 105:1989;764-769
33. Peterson J.M., Barbul A., Breslin R.J., Wasserkrug H.L., Efron G. Significance of T-lymphocytes in wound healing. Surgery. 102:1987;300-305
34. Barbul A., Breslin R.J., Woodyard J.P., Wasserkrug H.L., Efron G. The effect of in vivo T helper and T suppressor lymphocyte depletion on wound healing. Ann Surg. 209:1989;479-483
35. Efron J.E., Frankel H.L., Lazarou S.A., Wasserkrug H.L., Barbul A. Wound healing and T-lymphocytes. J Surg Res. 48:1990;460-463
36. Davis P.A., Corless D.J., Aspinall R., Wastell C. Effect of CD4(+) and CD8(+) cell depletion on wound healing. Br J Surg. 88:2001;298-304
37. De Carli M., Berthold S., Fickenscher H., et al. Immortalization with herpesvirus saimiri modulates the cytokine secretion profile of established Th1 and Th2 human T cell clones. J Immunol. 151:1993;5022-5030
38. Del Prete G. Human Th1 and Th2 lymphocytes their role in the pathophysiology of atopy. Allergy. 47:1992;450-455
39. + T cells. J Immunol. 168:2002;1181-1189
40. Stout R.D., Suttles J. T cell signaling of macrophage function in inflammatory disease. Front Biosci. 2:1997;d197-d206
41. Schaffer M., Barbul A. Lymphocyte function in wound healing and following injury. Br J Surg. 85:1998;444-460
42. Mills C.D., Kincaid K., Alt J.M., Heilman M.J., Hill A.M. M-1/M-2 macrophages and the Th1/Th2 paradigm. J Immunol. 164:2000;6166-6173
43. + T cells correlates with Th1/Th2 phenotype. J Immunol. 160:1998;5347-5354
44. Boyce D.E., Jones W.D., Ruge F., Harding K.G., Moore K. The role of lymphocytes in human dermal wound healing. Br J Dermatol. 143:2000;59-65
45. Ford H.R., Hoffman R.A., Wing E.J., Magee D.M., McIntyre L., Simmons R.L. Characterization of wound cytokines in the sponge matrix model. Arch Surg. 124:1989;1422-1428
46. Martin C.W., Muir I.F. The role of lymphocytes in wound healing. Br J Plast Surg. 43:1990;655-662