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Volumn 203, Issue 2, 2013, Pages 327-343

FOXO1 promotes wound healing through the up-regulation of TGF-β1 and prevention of oxidative stress

Author keywords

[No Author keywords available]

Indexed keywords

SMAD PROTEIN; TRANSCRIPTION FACTOR FKHR; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84887512241     PISSN: 00219525     EISSN: 15408140     Source Type: Journal    
DOI: 10.1083/jcb.201305074     Document Type: Article
Times cited : (149)

References (52)
  • 1
    • 0032763680 scopus 로고    scopus 로고
    • Matrix metalloproteinases (MMPs) are required for reepithelialization of cutaneous wounds
    • Agren, M.S. 1999. Matrix metalloproteinases (MMPs) are required for reepithelialization of cutaneous wounds. Arch. Dermatol. Res. 291:583-590. http://dx.doi.org/10.1007/s004030050459
    • (1999) Arch. Dermatol. Res. , vol.291 , pp. 583-590
    • Agren, M.S.1
  • 4
    • 0027219558 scopus 로고
    • Growth factors and wound healing: biochemical properties of growth factors and their receptors
    • Bennett, N.T., and G.S. Schultz. 1993. Growth factors and wound healing: biochemical properties of growth factors and their receptors. Am. J. Surg. 165:728-737. http://dx.doi.org/10.1016/S0002-9610(05)80797-4
    • (1993) Am. J. Surg. , vol.165 , pp. 728-737
    • Bennett, N.T.1    Schultz, G.S.2
  • 6
    • 0038003956 scopus 로고    scopus 로고
    • Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is offduty
    • Burgering, B.M., and R.H. Medema. 2003. Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is offduty. J. Leukoc. Biol. 73:689-701. http://dx.doi.org/10.1189/jlb.1202629
    • (2003) J. Leukoc. Biol. , vol.73 , pp. 689-701
    • Burgering, B.M.1    Medema, R.H.2
  • 7
    • 41849128523 scopus 로고    scopus 로고
    • The FoxO code
    • Calnan, D.R., and A. Brunet. 2008. The FoxO code. Oncogene. 27:2276-2288. http://dx.doi.org/10.1038/onc.2008.21
    • (2008) Oncogene , vol.27 , pp. 2276-2288
    • Calnan, D.R.1    Brunet, A.2
  • 8
    • 14844302370 scopus 로고    scopus 로고
    • Glutathione enhances fibroblast collagen contraction and protects keratinocytes from apoptosis in hyperglycaemic culture
    • Deveci, M., R.R. Gilmont, W.R. Dunham, B.P. Mudge, D.J. Smith, and C.L. Marcelo. 2005. Glutathione enhances fibroblast collagen contraction and protects keratinocytes from apoptosis in hyperglycaemic culture. Br. J. Dermatol. 152:217-224. http://dx.doi.org/10.1111/j.1365-2133.2004.06329.x
    • (2005) Br. J. Dermatol. , vol.152 , pp. 217-224
    • Deveci, M.1    Gilmont, R.R.2    Dunham, W.R.3    Mudge, B.P.4    Smith, D.J.5    Marcelo, C.L.6
  • 9
    • 0034609737 scopus 로고    scopus 로고
    • Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1
    • Dijkers, P.F., R.H. Medema, J.W. Lammers, L. Koenderman, and P.J. Coffer. 2000. Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1. Curr. Biol. 10:1201-1204. http://dx.doi.org/10.1016/S0960-9822(00)00728-4
    • (2000) Curr. Biol. , vol.10 , pp. 1201-1204
    • Dijkers, P.F.1    Medema, R.H.2    Lammers, J.W.3    Koenderman, L.4    Coffer, P.J.5
  • 10
    • 0037178789 scopus 로고    scopus 로고
    • FOXO forkhead transcription factors induce G(2)-M checkpoint in response to oxidative stress
    • Furukawa-Hibi, Y., K. Yoshida-Araki, T. Ohta, K. Ikeda, and N. Motoyama. 2002. FOXO forkhead transcription factors induce G(2)-M checkpoint in response to oxidative stress. J. Biol. Chem. 277:26729-26732. http://dx.doi.org/10.1074/jbc. C200256200
    • (2002) J. Biol. Chem. , vol.277 , pp. 26729-26732
    • Furukawa-Hibi, Y.1    Yoshida-Araki, K.2    Ohta, T.3    Ikeda, K.4    Motoyama, N.5
  • 11
    • 0034661826 scopus 로고    scopus 로고
    • Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues
    • Furuyama, T., T. Nakazawa, I. Nakano, and N. Mori. 2000. Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues. Biochem. J. 349:629-634. http://dx.doi.org/10.1042/0264-6021:3490629
    • (2000) Biochem. J. , vol.349 , pp. 629-634
    • Furuyama, T.1    Nakazawa, T.2    Nakano, I.3    Mori, N.4
  • 12
    • 0028168899 scopus 로고
    • TGF-beta 1 stimulates expression of keratinocyte integrins during re-epithelialization of cutaneous wounds
    • Gailit, J., M.P. Welch, and R.A. Clark. 1994. TGF-beta 1 stimulates expression of keratinocyte integrins during re-epithelialization of cutaneous wounds. J. Invest. Dermatol. 103:221-227. http://dx.doi.org/10.1111/1523-1747. ep12393176
    • (1994) J. Invest. Dermatol. , vol.103 , pp. 221-227
    • Gailit, J.1    Welch, M.P.2    Clark, R.A.3
  • 13
    • 35148832173 scopus 로고    scopus 로고
    • Loss of TGFbeta signaling destabilizes homeostasis and promotes squamous cell carcinomas in stratified epithelia
    • Guasch, G., M. Schober, H.A. Pasolli, E.B. Conn, L. Polak, and E. Fuchs. 2007. Loss of TGFbeta signaling destabilizes homeostasis and promotes squamous cell carcinomas in stratified epithelia. Cancer Cell. 12:313-327. http://dx.doi.org/10.1016/j.ccr.2007.08.020
    • (2007) Cancer Cell , vol.12 , pp. 313-327
    • Guasch, G.1    Schober, M.2    Pasolli, H.A.3    Conn, E.B.4    Polak, L.5    Fuchs, E.6
  • 14
    • 77749260633 scopus 로고    scopus 로고
    • Factors affecting wound healing
    • Guo, S., and L.A. Dipietro. 2010. Factors affecting wound healing. J. Dent. Res. 89:219-229. http://dx.doi.org/10.1177/0022034509359125
    • (2010) J. Dent. Res. , vol.89 , pp. 219-229
    • Guo, S.1    Dipietro, L.A.2
  • 15
    • 0023724933 scopus 로고
    • Stimulatory effects of transforming growth factor-beta and epidermal growth factor on epidermal cell outgrowth from porcine skin explant cultures
    • Hebda, P.A. 1988. Stimulatory effects of transforming growth factor-beta and epidermal growth factor on epidermal cell outgrowth from porcine skin explant cultures. J. Invest. Dermatol. 91:440-445. http://dx.doi.org/10.1111/1523-1747.ep12476480
    • (1988) J. Invest. Dermatol. , vol.91 , pp. 440-445
    • Hebda, P.A.1
  • 16
    • 41849108086 scopus 로고    scopus 로고
    • Many forks in the path: cycling with FoxO
    • Ho, K.K., S.S. Myatt, and E.W. Lam. 2008. Many forks in the path: cycling with FoxO. Oncogene. 27:2300-2311. http://dx.doi.org/10.1038/onc.2008.23
    • (2008) Oncogene , vol.27 , pp. 2300-2311
    • Ho, K.K.1    Myatt, S.S.2    Lam, E.W.3
  • 17
    • 78649716241 scopus 로고    scopus 로고
    • Transforming growth factor-?1 induces matrix metalloproteinase-9 and cell migration in astrocytes: roles of ROS-dependent ERK- and JNK-NF-?B pathways
    • Hsieh, H.L., H.H. Wang, W.B. Wu, P.J. Chu, and C.M. Yang. 2010. Transforming growth factor-?1 induces matrix metalloproteinase-9 and cell migration in astrocytes: roles of ROS-dependent ERK- and JNK-NF-?B pathways. J. Neuroinflammation. 7:88. http://dx.doi.org/10.1186/1742-2094-7-88
    • (2010) J. Neuroinflammation. , vol.7 , pp. 88
    • Hsieh, H.L.1    Wang, H.H.2    Wu, W.B.3    Chu, P.J.4    Yang, C.M.5
  • 18
    • 0031696891 scopus 로고    scopus 로고
    • The integrin alphavbeta6 is critical for keratinocyte migration on both its known ligand, fibronectin, and on vitronectin
    • Huang, X.Z., J.F. Wu, S. Spong, and D. Sheppard. 1998. The integrin alphavbeta6 is critical for keratinocyte migration on both its known ligand, fibronectin, and on vitronectin. J. Cell Sci. 111:2189-2195.
    • (1998) J. Cell Sci. , vol.111 , pp. 2189-2195
    • Huang, X.Z.1    Wu, J.F.2    Spong, S.3    Sheppard, D.4
  • 19
    • 28644451449 scopus 로고    scopus 로고
    • Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis
    • Ito, M., Y. Liu, Z. Yang, J. Nguyen, F. Liang, R.J. Morris, and G. Cotsarelis. 2005. Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis. Nat. Med. 11:1351-1354. http://dx.doi.org/10.1038/nm1328
    • (2005) Nat. Med. , vol.11 , pp. 1351-1354
    • Ito, M.1    Liu, Y.2    Yang, Z.3    Nguyen, J.4    Liang, F.5    Morris, R.J.6    Cotsarelis, G.7
  • 20
    • 0025830392 scopus 로고
    • Direct evidence for spatial and temporal regulation of transforming growth factor beta 1 expression during cutaneous wound healing
    • Kane, C.J., P.A. Hebda, J.N. Mansbridge, and P.C. Hanawalt. 1991. Direct evidence for spatial and temporal regulation of transforming growth factor beta 1 expression during cutaneous wound healing. J. Cell. Physiol. 148:157-173. http://dx.doi.org/10.1002/jcp.1041480119
    • (1991) J. Cell. Physiol. , vol.148 , pp. 157-173
    • Kane, C.J.1    Hebda, P.A.2    Mansbridge, J.N.3    Hanawalt, P.C.4
  • 21
    • 61849093110 scopus 로고    scopus 로고
    • Transforming growth factor beta1 signalling, wound healing and repair: a multifunctional cytokine with clinical implications for wound repair, a delicate balance
    • Klass, B.R., A.O. Grobbelaar, and K.J. Rolfe. 2009. Transforming growth factor beta1 signalling, wound healing and repair: a multifunctional cytokine with clinical implications for wound repair, a delicate balance. Postgrad. Med. J. 85:9-14. http://dx.doi.org/10.1136/pgmj.2008.069831
    • (2009) Postgrad. Med. J. , vol.85 , pp. 9-14
    • Klass, B.R.1    Grobbelaar, A.O.2    Rolfe, K.J.3
  • 22
    • 0027171393 scopus 로고
    • Hair follicle stem cells: their location, role in hair cycle, and involvement in skin tumor formation
    • Lavker, R.M., S. Miller, C. Wilson, G. Cotsarelis, Z.G. Wei, J.S. Yang, and T.T. Sun. 1993. Hair follicle stem cells: their location, role in hair cycle, and involvement in skin tumor formation. J. Invest. Dermatol. 101:16S-26S. http://dx.doi.org/10.1111/1523-1747.ep12362556
    • (1993) J. Invest. Dermatol. , vol.101
    • Lavker, R.M.1    Miller, S.2    Wilson, C.3    Cotsarelis, G.4    Wei, Z.G.5    Yang, J.S.6    Sun, T.T.7
  • 23
    • 33846627240 scopus 로고    scopus 로고
    • Pathophysiology of acute wound healing
    • Li, J., J. Chen, and R. Kirsner. 2007. Pathophysiology of acute wound healing. Clin. Dermatol. 25:9-18. http://dx.doi.org/10.1016/j.clindermatol.2006.09.007
    • (2007) Clin. Dermatol. , vol.25 , pp. 9-18
    • Li, J.1    Chen, J.2    Kirsner, R.3
  • 24
    • 34347218991 scopus 로고    scopus 로고
    • In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro
    • Liang, C.C., A.Y. Park, and J.L. Guan. 2007. In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro. Nat. Protoc. 2:329-333. http://dx.doi.org/10.1038/nprot.2007.30
    • (2007) Nat. Protoc. , vol.2 , pp. 329-333
    • Liang, C.C.1    Park, A.Y.2    Guan, J.L.3
  • 26
    • 75949103899 scopus 로고    scopus 로고
    • Integrin-TGF-beta crosstalk in fibrosis, cancer and wound healing
    • Margadant, C., and A. Sonnenberg. 2010. Integrin-TGF-beta crosstalk in fibrosis, cancer and wound healing. EMBO Rep. 11:97-105. http://dx.doi.org/10.1038/embor.2009.276
    • (2010) EMBO Rep , vol.11 , pp. 97-105
    • Margadant, C.1    Sonnenberg, A.2
  • 27
    • 0030934532 scopus 로고    scopus 로고
    • Wound healing-aiming for perfect skin regeneration
    • Martin, P. 1997. Wound healing-aiming for perfect skin regeneration. Science. 276:75-81. http://dx.doi.org/10.1126/science.276.5309.75
    • (1997) Science , vol.276 , pp. 75-81
    • Martin, P.1
  • 28
    • 27744543102 scopus 로고    scopus 로고
    • Inflammatory cells during wound repair: the good, the bad and the ugly
    • Martin, P., and S.J. Leibovich. 2005. Inflammatory cells during wound repair: the good, the bad and the ugly. Trends Cell Biol. 15:599-607. http://dx.doi.org/10.1016/j.tcb.2005.09.002
    • (2005) Trends Cell Biol , vol.15 , pp. 599-607
    • Martin, P.1    Leibovich, S.J.2
  • 29
    • 0034643331 scopus 로고    scopus 로고
    • AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1
    • Medema, R.H., G.J. Kops, J.L. Bos, and B.M. Burgering. 2000. AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1. Nature. 404:782-787. http://dx.doi.org/10.1038/35008115
    • (2000) Nature , vol.404 , pp. 782-787
    • Medema, R.H.1    Kops, G.J.2    Bos, J.L.3    Burgering, B.M.4
  • 30
    • 35548930209 scopus 로고    scopus 로고
    • The emerging roles of forkhead box (Fox) proteins in cancer
    • Myatt, S.S., and E.W. Lam. 2007. The emerging roles of forkhead box (Fox) proteins in cancer. Nat. Rev. Cancer. 7:847-859. http://dx.doi.org/10.1038/nrc2223
    • (2007) Nat. Rev. Cancer. , vol.7 , pp. 847-859
    • Myatt, S.S.1    Lam, E.W.2
  • 31
    • 0030926579 scopus 로고    scopus 로고
    • The involvement of reactive oxygen species and arachidonic acid in alpha 1-adrenoceptor-induced smooth muscle cell proliferation and migration
    • Nishio, E., and Y. Watanabe. 1997. The involvement of reactive oxygen species and arachidonic acid in alpha 1-adrenoceptor-induced smooth muscle cell proliferation and migration. Br. J. Pharmacol. 121:665-670. http://dx.doi.org/10.1038/sj.bjp.0701171
    • (1997) Br. J. Pharmacol. , vol.121 , pp. 665-670
    • Nishio, E.1    Watanabe, Y.2
  • 32
    • 33846295218 scopus 로고    scopus 로고
    • FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis
    • Paik, J.H., R. Kollipara, G. Chu, H. Ji, Y. Xiao, Z. Ding, L. Miao, Z. Tothova, J.W. Horner, D.R. Carrasco, et al. 2007. FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. Cell. 128:309-323. http://dx.doi.org/10.1016/j.cell.2006.12.029
    • (2007) Cell , vol.128 , pp. 309-323
    • Paik, J.H.1    Kollipara, R.2    Chu, G.3    Ji, H.4    Xiao, Y.5    Ding, Z.6    Miao, L.7    Tothova, Z.8    Horner, J.W.9    Carrasco, D.R.10
  • 33
    • 84858322507 scopus 로고    scopus 로고
    • Role of forkhead transcription factors in diabetes-induced oxidative stress
    • Ponugoti, B., G. Dong, and D.T. Graves. 2012. Role of forkhead transcription factors in diabetes-induced oxidative stress. Exp. Diabetes Res. 2012:939751. http://dx.doi.org/10.1155/2012/939751
    • (2012) Exp. Diabetes Res. , vol.2012 , pp. 939751
    • Ponugoti, B.1    Dong, G.2    Graves, D.T.3
  • 34
    • 34347232319 scopus 로고    scopus 로고
    • Wound reepithelialization: modulating keratinocyte migration in wound healing
    • Raja, K., K. Sivamani, M.S. Garcia, and R.R. Isseroff. 2007. Wound reepithelialization: modulating keratinocyte migration in wound healing. Front. Biosci. 12:2849-2868. http://dx.doi.org/10.2741/2277
    • (2007) Front. Biosci. , vol.12 , pp. 2849-2868
    • Raja, K.1    Sivamani, K.2    Garcia, M.S.3    Isseroff, R.R.4
  • 36
    • 51349161702 scopus 로고    scopus 로고
    • The role of oxygen in wound healing: a review of the literature
    • Rodriguez, P.G., F.N. Felix, D.T. Woodley, and E.K. Shim. 2008. The role of oxygen in wound healing: a review of the literature. Dermatol. Surg. 34:1159-1169. http://dx.doi.org/10.1111/j.1524-4725.2008.34254.x
    • (2008) Dermatol. Surg. , vol.34 , pp. 1159-1169
    • Rodriguez, P.G.1    Felix, F.N.2    Woodley, D.T.3    Shim, E.K.4
  • 37
    • 53249117183 scopus 로고    scopus 로고
    • Oxidative stress in normal and impaired wound repair
    • Schäfer, M., and S. Werner. 2008. Oxidative stress in normal and impaired wound repair. Pharmacol. Res. 58:165-171. http://dx.doi.org/10.1016/j.phrs.2008.06.004
    • (2008) Pharmacol. Res. , vol.58 , pp. 165-171
    • Schäfer, M.1    Werner, S.2
  • 38
    • 49349108793 scopus 로고    scopus 로고
    • Redox signals in wound healing
    • Sen, C.K., and S. Roy. 2008. Redox signals in wound healing. Biochim. Biophys. Acta. 1780:1348-1361. http://dx.doi.org/10.1016/j.bbagen.2008.01.006
    • (2008) Biochim. Biophys. Acta. , vol.1780 , pp. 1348-1361
    • Sen, C.K.1    Roy, S.2
  • 39
    • 79953186624 scopus 로고    scopus 로고
    • FoxO transcription factors promote cardiomyocyte survival upon induction of oxidative stress
    • Sengupta, A., J.D. Molkentin, J.H. Paik, R.A. DePinho, and K.E. Yutzey. 2011. FoxO transcription factors promote cardiomyocyte survival upon induction of oxidative stress. J. Biol. Chem. 286:7468-7478. http://dx.doi.org/10.1074/jbc. M110.179242
    • (2011) J. Biol. Chem. , vol.286 , pp. 7468-7478
    • Sengupta, A.1    Molkentin, J.D.2    Paik, J.H.3    DePinho, R.A.4    Yutzey, K.E.5
  • 40
    • 0024815224 scopus 로고
    • Urinary 8-hydroxy-2?-deoxyguanosine as a biological marker of in vivo oxidative DNA damage
    • Shigenaga, M.K., C.J. Gimeno, and B.N. Ames. 1989. Urinary 8-hydroxy-2?-deoxyguanosine as a biological marker of in vivo oxidative DNA damage. Proc. Natl. Acad. Sci. USA. 86:9697-9701. http://dx.doi.org/10.1073/pnas.86.24.9697
    • (1989) Proc. Natl. Acad. Sci. USA. , vol.86 , pp. 9697-9701
    • Shigenaga, M.K.1    Gimeno, C.J.2    Ames, B.N.3
  • 41
    • 0033517356 scopus 로고    scopus 로고
    • Cutaneous wound healing
    • Singer, A.J., and R.A. Clark. 1999. Cutaneous wound healing. N. Engl. J. Med. 341:738-746. http://dx.doi.org/10.1056/NEJM199909023411006
    • (1999) N. Engl. J. Med. , vol.341 , pp. 738-746
    • Singer, A.J.1    Clark, R.A.2
  • 42
    • 77949310647 scopus 로고    scopus 로고
    • Impaired wound healing in mouse models of diabetes is mediated by TNF-alpha dysregulation and associated with enhanced activation of forkhead box O1 (FOXO1)
    • Siqueira, M.F., J. Li, L. Chehab, T. Desta, T. Chino, N. Krothpali, Y. Behl, M. Alikhani, J. Yang, C. Braasch, and D.T. Graves. 2010. Impaired wound healing in mouse models of diabetes is mediated by TNF-alpha dysregulation and associated with enhanced activation of forkhead box O1 (FOXO1). Diabetologia. 53:378-388. http://dx.doi.org/10.1007/s00125-009-1529-y
    • (2010) Diabetologia , vol.53 , pp. 378-388
    • Siqueira, M.F.1    Li, J.2    Chehab, L.3    Desta, T.4    Chino, T.5    Krothpali, N.6    Behl, Y.7    Alikhani, M.8    Yang, J.9    Braasch, C.10    Graves, D.T.11
  • 43
    • 33645699825 scopus 로고    scopus 로고
    • Role of nitric oxide, nitroxidative and oxidative stress in wound healing
    • Soneja, A., M. Drews, and T. Malinski. 2005. Role of nitric oxide, nitroxidative and oxidative stress in wound healing. Pharmacol. Rep. 57(Suppl):108-119.
    • (2005) Pharmacol. Rep. , vol.57 , Issue.SUPPL. , pp. 108-119
    • Soneja, A.1    Drews, M.2    Malinski, T.3
  • 44
    • 79251548626 scopus 로고    scopus 로고
    • Forkhead homeobox type O transcription factors in the responses to oxidative stress
    • Storz, P. 2011. Forkhead homeobox type O transcription factors in the responses to oxidative stress. Antioxid. Redox Signal. 14:593-605. http://dx.doi.org/10.1089/ars.2010.3405
    • (2011) Antioxid. Redox Signal. , vol.14 , pp. 593-605
    • Storz, P.1
  • 46
    • 0037134040 scopus 로고    scopus 로고
    • DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein
    • Tran, H., A. Brunet, J.M. Grenier, S.R. Datta, A.J. Fornace Jr., P.S. DiStefano, L.W. Chiang, and M.E. Greenberg. 2002. DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science. 296:530-534. http://dx.doi.org/10.1126/science.1068712
    • (2002) Science , vol.296 , pp. 530-534
    • Tran, H.1    Brunet, A.2    Grenier, J.M.3    Datta, S.R.4    Fornace Jr., A.J.5    DiStefano, P.S.6    Chiang, L.W.7    Greenberg, M.E.8
  • 47
    • 0027058483 scopus 로고    scopus 로고
    • Stimulation of keratinocyte migration by growth factors
    • Tsuboi, R., C. Sato, C.M. Shi, and H. Ogawa. 1992. Stimulation of keratinocyte migration by growth factors. J. Dermatol. 19:652-653.
    • J. Dermatol. , vol.19 , pp. 652-653
    • Tsuboi, R.1    Sato, C.2    Shi, C.M.3    Ogawa, H.4
  • 48
    • 34249281690 scopus 로고    scopus 로고
    • Stressing the role of FoxO proteins in lifespan and disease
    • van der Horst, A., and B.M. Burgering. 2007. Stressing the role of FoxO proteins in lifespan and disease. Nat. Rev. Mol. Cell Biol. 8:440-450. http://dx.doi.org/10.1038/nrm2190
    • (2007) Nat. Rev. Mol. Cell Biol , vol.8 , pp. 440-450
    • van der Horst, A.1    Burgering, B.M.2
  • 49
    • 0033520497 scopus 로고    scopus 로고
    • Stable overexpression of manganese superoxide dismutase in mitochondria identifies hydrogen peroxide as a major oxidant in the AP-1-mediated induction of matrix-degrading metalloprotease-1
    • Wenk, J., P. Brenneisen, M. Wlaschek, A. Poswig, K. Briviba, T.D. Oberley, and K. Scharffetter-Kochanek. 1999. Stable overexpression of manganese superoxide dismutase in mitochondria identifies hydrogen peroxide as a major oxidant in the AP-1-mediated induction of matrix-degrading metalloprotease-1. J. Biol. Chem. 274:25869-25876. http://dx.doi.org/10.1074/jbc.274.36.25869
    • (1999) J. Biol. Chem. , vol.274 , pp. 25869-25876
    • Wenk, J.1    Brenneisen, P.2    Wlaschek, M.3    Poswig, A.4    Briviba, K.5    Oberley, T.D.6    Scharffetter-Kochanek, K.7
  • 50
    • 0038676258 scopus 로고    scopus 로고
    • Regulation of wound healing by growth factors and cytokines
    • Werner, S., and R. Grose. 2003. Regulation of wound healing by growth factors and cytokines. Physiol. Rev. 83:835-870.
    • (2003) Physiol. Rev. , vol.83 , pp. 835-870
    • Werner, S.1    Grose, R.2
  • 51
    • 65549088833 scopus 로고    scopus 로고
    • High glucose suppresses epidermal growth factor receptor/phosphatidylinositol 3-kinase/Akt signaling pathway and attenuates corneal epithelial wound healing
    • Xu, K.P., Y. Li, A.V. Ljubimov, and F.S. Yu. 2009. High glucose suppresses epidermal growth factor receptor/phosphatidylinositol 3-kinase/Akt signaling pathway and attenuates corneal epithelial wound healing. Diabetes. 58:1077-1085. http://dx.doi.org/10.2337/db08-0997
    • (2009) Diabetes , vol.58 , pp. 1077-1085
    • Xu, K.P.1    Li, Y.2    Ljubimov, A.V.3    Yu, F.S.4
  • 52
    • 0028987192 scopus 로고
    • Transforming growth factor-beta 1 modulates beta 1 and beta 5 integrin receptors and induces the de novo expression of the alpha v beta 6 heterodimer in normal human keratinocytes: implications for wound healing
    • Zambruno, G., P.C. Marchisio, A. Marconi, C. Vaschieri, A. Melchiori, A. Giannetti, and M. De Luca. 1995. Transforming growth factor-beta 1 modulates beta 1 and beta 5 integrin receptors and induces the de novo expression of the alpha v beta 6 heterodimer in normal human keratinocytes: implications for wound healing. J. Cell Biol. 129:853-865. http://dx.doi.org/10.1083/jcb.129.3.853
    • (1995) J. Cell Biol. , vol.129 , pp. 853-865
    • Zambruno, G.1    Marchisio, P.C.2    Marconi, A.3    Vaschieri, C.4    Melchiori, A.5    Giannetti, A.6    De Luca, M.7


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