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Volumn 28, Issue 6, 2014, Pages 850-857

Topical application of the bee hive protectant propolis is well tolerated and improves human diabetic foot ulcer healing in a prospective feasibility study

Author keywords

Bacteria; Diabetic foot ulcer; MMP 9; Pilot; Propolis

Indexed keywords

GELATINASE A; GELATINASE B; PROPOLIS; PROTECTIVE AGENT; WOUND HEALING PROMOTING AGENT; ANTIINFECTIVE AGENT; TOPICAL ANTIINFECTIVE AGENT;

EID: 84908300106     PISSN: 10568727     EISSN: 1873460X     Source Type: Journal    
DOI: 10.1016/j.jdiacomp.2014.07.012     Document Type: Article
Times cited : (60)

References (53)
  • 1
    • 0032771893 scopus 로고    scopus 로고
    • Consensus Development Conference on Diabetic Foot Wound Care: 7-8 April 1999, Boston, Massachusetts
    • American Diabetes Association Consensus Development Conference on Diabetic Foot Wound Care: 7-8 April 1999, Boston, Massachusetts Diabetes Care 22 1999 1354 1360
    • (1999) Diabetes Care , vol.22 , pp. 1354-1360
  • 2
    • 84881080571 scopus 로고    scopus 로고
    • Wound-healing effects of low-level laser therapy in diabetic rats involve the modulation of MMP-2 and MMP-9 and the redistribution of collagen types i and III
    • A. Aparecida Da Silva, E.C. Leal-Junior, A.C. Alves, C.S. Rambo, S.A. Dos Santos, and R.P. Vieira Wound-healing effects of low-level laser therapy in diabetic rats involve the modulation of MMP-2 and MMP-9 and the redistribution of collagen types I and III Journal of Cosmetic and Laser Therapy 15 2013 210 216
    • (2013) Journal of Cosmetic and Laser Therapy , vol.15 , pp. 210-216
    • Aparecida Da Silva, A.1    Leal-Junior, E.C.2    Alves, A.C.3    Rambo, C.S.4    Dos Santos, S.A.5    Vieira, R.P.6
  • 3
    • 84883223211 scopus 로고    scopus 로고
    • Antimicrobial activity of propolis special extract GH 2002 against multidrug-resistant clinical isolates
    • A. Astani, S. Zimmermann, E. Hassan, J. Reichling, K.H. Sensch, and P. Schnitzler Antimicrobial activity of propolis special extract GH 2002 against multidrug-resistant clinical isolates Pharmazie 68 2013 695 701
    • (2013) Pharmazie , vol.68 , pp. 695-701
    • Astani, A.1    Zimmermann, S.2    Hassan, E.3    Reichling, J.4    Sensch, K.H.5    Schnitzler, P.6
  • 4
    • 0033976532 scopus 로고    scopus 로고
    • Propolis: Recent advances in chemistry and plant origin
    • V.S. Bankova, S.L. De Castro, and M.C. Marcucci Propolis: Recent advances in chemistry and plant origin Apidologie 31 2000 3 15
    • (2000) Apidologie , vol.31 , pp. 3-15
    • Bankova, V.S.1    De Castro, S.L.2    Marcucci, M.C.3
  • 6
  • 7
    • 51249168939 scopus 로고
    • The composition, active components and bacteriostatic activity of propolis in dietetics
    • J.S. Bonvehi, and F.V. Coll The composition, active components and bacteriostatic activity of propolis in dietetics Journal of the American Oil Chemists Society 71 1994 529 532
    • (1994) Journal of the American Oil Chemists Society , vol.71 , pp. 529-532
    • Bonvehi, J.S.1    Coll, F.V.2
  • 9
    • 84882272855 scopus 로고    scopus 로고
    • Propolis and its constituent caffeic acid suppress LPS-stimulated pro-inflammatory response by blocking NF-kappaB and MAPK activation in macrophages
    • M.C. Bufalo, I. Ferreira, G. Costa, V. Francisco, J. Liberal, and M.T. Cruz Propolis and its constituent caffeic acid suppress LPS-stimulated pro-inflammatory response by blocking NF-kappaB and MAPK activation in macrophages Journal of Ethnopharmacology 149 2013 84 92
    • (2013) Journal of Ethnopharmacology , vol.149 , pp. 84-92
    • Bufalo, M.C.1    Ferreira, I.2    Costa, G.3    Francisco, V.4    Liberal, J.5    Cruz, M.T.6
  • 12
    • 52149084627 scopus 로고    scopus 로고
    • Antimicrobial effects of Turkish propolis, pollen, and laurel on spoilage and pathogenic food-related microorganisms
    • O. Erkmen, and M.M. Ozcan Antimicrobial effects of Turkish propolis, pollen, and laurel on spoilage and pathogenic food-related microorganisms Journal of Medicinal Food 11 2008 587 592
    • (2008) Journal of Medicinal Food , vol.11 , pp. 587-592
    • Erkmen, O.1    Ozcan, M.M.2
  • 13
    • 27744448125 scopus 로고    scopus 로고
    • Wound healing and its impairment in the diabetic foot
    • V. Falanga Wound healing and its impairment in the diabetic foot Lancet 366 2005 1736 1743
    • (2005) Lancet , vol.366 , pp. 1736-1743
    • Falanga, V.1
  • 18
    • 0023838394 scopus 로고
    • Preferential cytotoxicity on tumor cells by caffeic acid phenethyl ester isolated from propolis
    • D. Grunberger, R. Banerjee, K. Eisinger, E.M. Oltz, L. Efros, and M. Caldwell Preferential cytotoxicity on tumor cells by caffeic acid phenethyl ester isolated from propolis Experientia 44 1988 230 232
    • (1988) Experientia , vol.44 , pp. 230-232
    • Grunberger, D.1    Banerjee, R.2    Eisinger, K.3    Oltz, E.M.4    Efros, L.5    Caldwell, M.6
  • 19
    • 27744466146 scopus 로고    scopus 로고
    • Caffeic acid phenyl ester in propolis is a strong inhibitor of matrix metalloproteinase-9 and invasion inhibitor: Isolation and identification
    • U.H. Jin, T.W. Chung, S.K. Kang, S.J. Suh, J.K. Kim, and K.H. Chung Caffeic acid phenyl ester in propolis is a strong inhibitor of matrix metalloproteinase-9 and invasion inhibitor: Isolation and identification Clinica Chimica Acta 362 2005 57 64
    • (2005) Clinica Chimica Acta , vol.362 , pp. 57-64
    • Jin, U.H.1    Chung, T.W.2    Kang, S.K.3    Suh, S.J.4    Kim, J.K.5    Chung, K.H.6
  • 20
    • 29244472483 scopus 로고    scopus 로고
    • Flavonoid analysis and antimicrobial activity of commercially available propolis products
    • I. Kosalec, S. Pepeljnjak, M. Bakmaz, and S. Vladimir-Knezevic Flavonoid analysis and antimicrobial activity of commercially available propolis products Acta Pharmaceutica 55 2005 423 430
    • (2005) Acta Pharmaceutica , vol.55 , pp. 423-430
    • Kosalec, I.1    Pepeljnjak, S.2    Bakmaz, M.3    Vladimir-Knezevic, S.4
  • 21
    • 0036247632 scopus 로고    scopus 로고
    • Ratios of activated matrix metalloproteinase-9 to tissue inhibitor of matrix metalloproteinase-1 in wound fluids are inversely correlated with healing of pressure ulcers
    • G.P. Ladwig, M.C. Robson, R. Liu, M.A. Kuhn, D.F. Muir, and G.S. Schultz Ratios of activated matrix metalloproteinase-9 to tissue inhibitor of matrix metalloproteinase-1 in wound fluids are inversely correlated with healing of pressure ulcers Wound Repair and Regeneration 10 2002 26 37
    • (2002) Wound Repair and Regeneration , vol.10 , pp. 26-37
    • Ladwig, G.P.1    Robson, M.C.2    Liu, R.3    Kuhn, M.A.4    Muir, D.F.5    Schultz, G.S.6
  • 22
    • 84876523196 scopus 로고    scopus 로고
    • Systematic review of the effectiveness of hyperbaric oxygenation therapy in the management of chronic diabetic foot ulcers
    • R. Liu, L. Li, M. Yang, G. Boden, and G. Yang Systematic review of the effectiveness of hyperbaric oxygenation therapy in the management of chronic diabetic foot ulcers Mayo Clinic Proceedings 88 2013 166 175
    • (2013) Mayo Clinic Proceedings , vol.88 , pp. 166-175
    • Liu, R.1    Li, L.2    Yang, M.3    Boden, G.4    Yang, G.5
  • 23
    • 64549119604 scopus 로고    scopus 로고
    • Increased matrix metalloproteinase-9 predicts poor wound healing in diabetic foot ulcers
    • Y. Liu, D. Min, T. Bolton, V. Nubé, S.M. Twigg, and D.K. Yue Increased matrix metalloproteinase-9 predicts poor wound healing in diabetic foot ulcers Diabetes Care 32 2009 117 119
    • (2009) Diabetes Care , vol.32 , pp. 117-119
    • Liu, Y.1    Min, D.2    Bolton, T.3    Nubé, V.4    Twigg, S.M.5    Yue, D.K.6
  • 24
    • 33845944797 scopus 로고    scopus 로고
    • Combined use of honey, bee propolis and myrrh in healing a deep, infected wound in a patient with diabetes mellitus
    • M. Lotfy, G. Badra, W. Burham, and F.Q. Alenzi Combined use of honey, bee propolis and myrrh in healing a deep, infected wound in a patient with diabetes mellitus British Journal of Biomedical Science 63 2006 171 173
    • (2006) British Journal of Biomedical Science , vol.63 , pp. 171-173
    • Lotfy, M.1    Badra, G.2    Burham, W.3    Alenzi, F.Q.4
  • 25
    • 51349114196 scopus 로고    scopus 로고
    • The anti-inflammatory agent propolis improves wound healing in a rodent model of experimental diabetes
    • S.V. McLennan, J. Bonner, S. Milne, L. Lo, A. Charlton, and S. Kurup The anti-inflammatory agent propolis improves wound healing in a rodent model of experimental diabetes Wound Repair and Regeneration 16 2008 706 713
    • (2008) Wound Repair and Regeneration , vol.16 , pp. 706-713
    • McLennan, S.V.1    Bonner, J.2    Milne, S.3    Lo, L.4    Charlton, A.5    Kurup, S.6
  • 28
    • 0031238824 scopus 로고    scopus 로고
    • Antimicrobial action of propolis and some of its components: The effects on growth, membrane potential and motility of bacteria
    • O.K. Mirzoeva, R.N. Grishanin, and P.C. Calder Antimicrobial action of propolis and some of its components: The effects on growth, membrane potential and motility of bacteria Microbiological Research 152 1997 239 246
    • (1997) Microbiological Research , vol.152 , pp. 239-246
    • Mirzoeva, O.K.1    Grishanin, R.N.2    Calder, P.C.3
  • 32
    • 0035135501 scopus 로고    scopus 로고
    • A comparison of two diabetic foot ulcer classification systems: The Wagner and the University of Texas wound classification systems
    • S.O. Oyibo, E.B. Jude, I. Tarawneh, H.C. Nguyen, L.B. Harkless, and A.J. Boulton A comparison of two diabetic foot ulcer classification systems: The Wagner and the University of Texas wound classification systems Diabetes Care 24 2001 84 88
    • (2001) Diabetes Care , vol.24 , pp. 84-88
    • Oyibo, S.O.1    Jude, E.B.2    Tarawneh, I.3    Nguyen, H.C.4    Harkless, L.B.5    Boulton, A.J.6
  • 33
    • 7044253545 scopus 로고    scopus 로고
    • Galangin expresses bactericidal activity against multiple-resistant bacteria: MRSA, Enterococcus spp. and Pseudomonas aeruginosa
    • S. Pepeljnjak, and I. Kosalec Galangin expresses bactericidal activity against multiple-resistant bacteria: MRSA, Enterococcus spp. and Pseudomonas aeruginosa FEMS Microbiology Letters 240 2004 111 116
    • (2004) FEMS Microbiology Letters , vol.240 , pp. 111-116
    • Pepeljnjak, S.1    Kosalec, I.2
  • 34
    • 79954590766 scopus 로고    scopus 로고
    • Gene expression of pro-inflammatory cytokines and neuropeptides in diabetic wound healing
    • L. Pradhan, X. Cai, S. Wu, N.D. Andersen, M. Martin, and J. Malek Gene expression of pro-inflammatory cytokines and neuropeptides in diabetic wound healing Journal of Surgical Research 167 2011 336 342
    • (2011) Journal of Surgical Research , vol.167 , pp. 336-342
    • Pradhan, L.1    Cai, X.2    Wu, S.3    Andersen, N.D.4    Martin, M.5    Malek, J.6
  • 35
    • 41849139963 scopus 로고    scopus 로고
    • Prediction of outcome in individuals with diabetic foot ulcers: Focus on the differences between individuals with and without peripheral arterial disease the EURODIALE Study
    • L. Prompers, N. Schaper, J. Apelqvist, M. Edmonds, E.B. Jude, and D. Mauricio Prediction of outcome in individuals with diabetic foot ulcers: Focus on the differences between individuals with and without peripheral arterial disease. The EURODIALE Study Diabetologia 51 2008 747 755
    • (2008) Diabetologia , vol.51 , pp. 747-755
    • Prompers, L.1    Schaper, N.2    Apelqvist, J.3    Edmonds, M.4    Jude, E.B.5    Mauricio, D.6
  • 38
    • 0036865289 scopus 로고    scopus 로고
    • Antioxidant activity of propolis: Role of caffeic acid phenethyl ester and galangin
    • A. Russo, R. Longo, and A. Vanella Antioxidant activity of propolis: Role of caffeic acid phenethyl ester and galangin Fitoterapia 73 Suppl. 1 2002 S21 S29
    • (2002) Fitoterapia , vol.73 , pp. 21-S29
    • Russo, A.1    Longo, R.2    Vanella, A.3
  • 39
    • 0005804003 scopus 로고
    • Biological properties and clinical application of propolis. III. Investigation of the sensitivity of Staphylococci isolated from pathological cases to ethanol extract of propolis (EEP). Attempts on inducing resistance in laboratory Staphylococcus strain to EEP
    • S. Scheller, J. Tustanowski, B. Kurylo, Z. Paradowski, and Z. Obuszko Biological properties and clinical application of propolis. III. Investigation of the sensitivity of Staphylococci isolated from pathological cases to ethanol extract of propolis (EEP). Attempts on inducing resistance in laboratory Staphylococcus strain to EEP Arzneimittel-Forschung 27 1977 1395
    • (1977) Arzneimittel-Forschung , vol.27 , pp. 1395
    • Scheller, S.1    Tustanowski, J.2    Kurylo, B.3    Paradowski, Z.4    Obuszko, Z.5
  • 40
    • 84875532294 scopus 로고    scopus 로고
    • A prospective, non comparative, multicenter study to investigate the effect of cadexomer iodine on bioburden load and other wound characteristics in diabetic foot ulcers
    • J.A. Schwartz, JCn Lantis, C. Gendics, A.M. Fuller, W. Payne, and D. Ochs A prospective, non comparative, multicenter study to investigate the effect of cadexomer iodine on bioburden load and other wound characteristics in diabetic foot ulcers International Wound Journal 10 2013 193 199
    • (2013) International Wound Journal , vol.10 , pp. 193-199
    • Schwartz, J.A.1    Lantis, J.2    Gendics, C.3    Fuller, A.M.4    Payne, W.5    Ochs, D.6
  • 41
    • 78651407339 scopus 로고    scopus 로고
    • Propolis: Is there a potential for the development of new drugs?
    • J.M. Sforcin, and V. Bankova Propolis: Is there a potential for the development of new drugs? Journal of Ethnopharmacology 133 2011 253 260
    • (2011) Journal of Ethnopharmacology , vol.133 , pp. 253-260
    • Sforcin, J.M.1    Bankova, V.2
  • 42
    • 35348829375 scopus 로고    scopus 로고
    • The clinical effect of topical phenytoin on wound healing: A systematic review
    • J. Shaw, C.M. Hughes, K.M. Lagan, and P.M. Bell The clinical effect of topical phenytoin on wound healing: A systematic review British Journal of Dermatology 157 2007 997 1004
    • (2007) British Journal of Dermatology , vol.157 , pp. 997-1004
    • Shaw, J.1    Hughes, C.M.2    Lagan, K.M.3    Bell, P.M.4
  • 43
    • 80053014487 scopus 로고    scopus 로고
    • The effect of topical phenytoin on healing in diabetic foot ulcers: A randomized controlled trial
    • J. Shaw, C.M. Hughes, K.M. Lagan, M.R. Stevenson, C.R. Irwin, and P.M. Bell The effect of topical phenytoin on healing in diabetic foot ulcers: A randomized controlled trial Diabetic Medicine 28 2011 1154 1157
    • (2011) Diabetic Medicine , vol.28 , pp. 1154-1157
    • Shaw, J.1    Hughes, C.M.2    Lagan, K.M.3    Stevenson, M.R.4    Irwin, C.R.5    Bell, P.M.6
  • 45
    • 33748272307 scopus 로고    scopus 로고
    • Percent change in wound area of diabetic foot ulcers over a 4-week period is a robust predictor of complete healing in a 12-week prospective trial
    • P. Sheehan, P. Jones, J.M. Giurini, A. Caselli, and A. Veves Percent change in wound area of diabetic foot ulcers over a 4-week period is a robust predictor of complete healing in a 12-week prospective trial Plastic and Reconstructive Surgery 17 2006 239S 244S
    • (2006) Plastic and Reconstructive Surgery , vol.17 , pp. 239S-244S
    • Sheehan, P.1    Jones, P.2    Giurini, J.M.3    Caselli, A.4    Veves, A.5
  • 46
    • 0031656215 scopus 로고    scopus 로고
    • Physiology and healing dynamics of chronic cutaneous wounds
    • W.K. Stadelmann, and A.G. Digenis Physiology and healing dynamics of chronic cutaneous wounds American Journal of Surgery 176 1998 26S 38S
    • (1998) American Journal of Surgery , vol.176 , pp. 26S-38S
    • Stadelmann, W.K.1    Digenis, A.G.2
  • 47
    • 61849184930 scopus 로고    scopus 로고
    • 15-Deoxy-Delta(12,14)-prostaglandin J(2) inhibits fibrogenic response in human hepatoma cells
    • F.M. Suk, C.H. Chen, S.Y. Lin, C.J. Cheng, S.J. Yen, and L.F. Hung 15-Deoxy-Delta(12,14)-prostaglandin J(2) inhibits fibrogenic response in human hepatoma cells Toxicology Letters 187 2009 22 27
    • (2009) Toxicology Letters , vol.187 , pp. 22-27
    • Suk, F.M.1    Chen, C.H.2    Lin, S.Y.3    Cheng, C.J.4    Yen, S.J.5    Hung, L.F.6
  • 48
    • 84908280844 scopus 로고    scopus 로고
    • Role of propolis on biochemical parameters in kidney and heart tissues against l-NAME induced oxidative injury in rats
    • [Ahead of print; PMID: 24490594]
    • Z.S. Talas, I. Ozdemir, O. Ciftci, O. Cakir, M.F. Gulhan, and O.M. Pasaoglu Role of propolis on biochemical parameters in kidney and heart tissues against l-NAME induced oxidative injury in rats Clinical and Experimental Hypertension 2014 [Ahead of print; PMID: 24490594]
    • (2014) Clinical and Experimental Hypertension
    • Talas, Z.S.1    Ozdemir, I.2    Ciftci, O.3    Cakir, O.4    Gulhan, M.F.5    Pasaoglu, O.M.6
  • 49
    • 84893763071 scopus 로고    scopus 로고
    • Propolis: A wonder bees product and its pharmacological potentials
    • V.D. Wagh Propolis: A wonder bees product and its pharmacological potentials Advances in Pharmacological Sciences 2013 10.1155/2013/308249
    • (2013) Advances in Pharmacological Sciences
    • Wagh, V.D.1
  • 50
    • 84893763071 scopus 로고    scopus 로고
    • Propolis: A wonder bees product and its pharmacological potentials
    • V.D. Wagh Propolis: A wonder bees product and its pharmacological potentials Advances in Pharmacological Sciences 2013 2013 308249
    • (2013) Advances in Pharmacological Sciences , vol.2013 , pp. 308249
    • Wagh, V.D.1
  • 51
    • 84883163448 scopus 로고    scopus 로고
    • Susceptibility of Staphylococcus aureus clinical isolates to propolis extract alone or in combination with antimicrobial drugs
    • R.D. Wojtyczka, A. Dziedzic, D. Idzik, M. Kepa, R. Kubina, and A. Kabala-Dzik Susceptibility of Staphylococcus aureus clinical isolates to propolis extract alone or in combination with antimicrobial drugs Molecules 18 2013 9623 9640
    • (2013) Molecules , vol.18 , pp. 9623-9640
    • Wojtyczka, R.D.1    Dziedzic, A.2    Idzik, D.3    Kepa, M.4    Kubina, R.5    Kabala-Dzik, A.6
  • 52
    • 0035348591 scopus 로고    scopus 로고
    • Geographic variation of lower-extremity major amputation in individuals with and without diabetes in the Medicare population
    • J.S. Wrobel, J.A. Mayfield, and R. GE Geographic variation of lower-extremity major amputation in individuals with and without diabetes in the Medicare population Diabetes Care 24 2005 860 864
    • (2005) Diabetes Care , vol.24 , pp. 860-864
    • Wrobel, J.S.1    Mayfield, J.A.2    Ge, R.3
  • 53
    • 33846673915 scopus 로고    scopus 로고
    • Bacterial load predicts healing rate in neuropathic diabetic foot ulcers
    • L. Xu, S.V. McLennan, L. Lo, A. Natfaji, T. Bolton, and Y. Liu Bacterial load predicts healing rate in neuropathic diabetic foot ulcers Diabetes Care 30 2007 378 380
    • (2007) Diabetes Care , vol.30 , pp. 378-380
    • Xu, L.1    McLennan, S.V.2    Lo, L.3    Natfaji, A.4    Bolton, T.5    Liu, Y.6


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