GSK3β inhibition protects the immature brain from hypoxic-ischaemic insult via reduced STAT3 signalling

Neuropharmacology

Volumn 101, Issue , 2016, Pages 13-23

  D'Angelo, Barbara ^a   Joakim Ek, C ^a   Sun, Yanyan ^b   Zhu, Changlian ^b   Sandberg, Mats ^c   Mallard, Carina ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

GSK3 ; Hypoxia ischaemia; Neuroinflammation; Oxidative stress; Perinatal; STAT3

Indexed keywords

2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; CASPASE 3; GLYCOGEN SYNTHASE KINASE 3BETA; INTERLEUKIN 10; INTERLEUKIN 6; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; DOUBLECORTIN PROTEIN; ENZYME INHIBITOR; GLYCOGEN SYNTHASE KINASE 3; GSK3B PROTEIN, MOUSE; INDOLE DERIVATIVE; MALEIMIDE DERIVATIVE; MICROTUBULE ASSOCIATED PROTEIN; NERVE PROTEIN; NEUROPEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BRAIN BLOOD FLOW; BRAIN HYPOXIA; BRAIN INFARCTION SIZE; CELL DEATH; CELL FRACTIONATION; CELL LOSS; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE RELEASE; ENCEPHALITIS; ENZYME ACTIVATION; ENZYME INHIBITION; GENE; GENE EXPRESSION; GENE TRANSLOCATION; GLIA CELL; IL 10 GENE; IL 6 GENE; MOUSE; NERVE CELL; NEUROPROTECTION; NEWBORN; NONHUMAN; PGC1ALPHA GENE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SOD2 GENE; TNFALPHA GENE; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN; BRAIN CIRCULATION; BRAIN INFARCTION; C57BL MOUSE; DISEASE MODEL; DRUG ADMINISTRATION; DRUG EFFECTS; GENETICS; HIPPOCAMPUS; HYPOXIA-ISCHEMIA, BRAIN; METABOLISM; PATHOLOGY; STEM CELL;

ANIMALS; ANIMALS, NEWBORN; BRAIN; BRAIN INFARCTION; CASPASE 3; CEREBROVASCULAR CIRCULATION; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION SCHEDULE; ENZYME INHIBITORS; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; HIPPOCAMPUS; HYPOXIA-ISCHEMIA, BRAIN; INDOLES; MALEIMIDES; MICE; MICE, INBRED C57BL; MICROTUBULE-ASSOCIATED PROTEINS; NERVE TISSUE PROTEINS; NEUROPEPTIDES; STAT3 TRANSCRIPTION FACTOR; STEM CELLS; SUBCELLULAR FRACTIONS;

EID: 84942279106     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2015.09.017     Document Type: Article

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