Presenting native-like HIV-1 envelope trimers on ferritin nanoparticles improves their immunogenicity

Retrovirology

Volumn 12, Issue 1, 2015, Pages

  Sliepen, Kwinten ^a   Ozorowski, Gabriel ^b   Burger, Judith A ^a   Van Montfort, Thijs ^a   Stunnenberg, Melissa ^a   LaBranche, Celia ^c   Montefiori, David C ^c   Moore, John P ^d   Ward, Andrew B ^b   Sanders, Rogier W ^a,d  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

BG505; Envelope glycoprotein; Ferritin; HIV 1; Nanoparticles; SOSIP; Vaccine

Indexed keywords

FERRITIN NANOPARTICLE; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; NANOPARTICLE; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; FERRITIN; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIGEN ANTIBODY REACTION; ARTICLE; CONTROLLED STUDY; DRUG BINDING; DRUG DESIGN; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNIZATION; IMMUNOGENICITY; MOUSE; NONHUMAN; PROTEIN TRANSPORT; RABBIT; ANIMAL; BIOSYNTHESIS; CHEMISTRY; FEMALE; HUMAN; IMMUNOLOGY; PROTEIN MULTIMERIZATION;

AIDS VACCINES; ANIMALS; ANTIBODIES, NEUTRALIZING; ENV GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; FEMALE; FERRITINS; HIV ANTIBODIES; HIV-1; HUMANS; IMMUNIZATION; MICE; NANOPARTICLES; PROTEIN MULTIMERIZATION; RABBITS;

EID: 84942254962     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/s12977-015-0210-4     Document Type: Article

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