Lung Morphogenesis, Role of Growth Factors and Transcription Factors

The Lung: Development, Aging and The Environment

Volumn , Issue , 2003, Pages 4-11

  Cardoso, Wellington V ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84942254741     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012324751-3/50035-8     Document Type: Chapter

References (89)

1. Wells JM, Melton DA Vertebrate endoderm development. Ann. Rev. Cell Dev. Biol. 1993, 15:393-410.
2. Matsumoto K, Yoshitomi H, Rossant J, et al. Liver organogenesis promoted by endotherlial cells prior to vascular function. Science 2001, 294:559-563.
3. Lammert E, Cleaver O, Melton D Induction of pancreatic differentiation by signals from blood vessels. Science 2001, 294:564-567.
4. Jung J, Zheng M, Goldfarb M, et al. Initiation of mammalian liver development from endoderm by fibroblast growth factors. Science 1993, 284:1998-2003.
5. Rossi JM, Dunn NR, Hogan BL, et al. Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm. Genes Dev. 2001, 15:1998-2009.
6. Hebrok M, Kim SK, Melton DA Notochord repression of endodermal Sonic hedgehog permits pancreas development. Genes Dev. 1998, 12:725-731.
7. Kim SK, Hebrok M, Melton DA Notochord to endoderm signalling is required for pancreas development. Development 1997, 124:4243-4252.
8. Pringle KC Human fetal lung development and related animal models. Clin. Obst. Gynecol. 1986, 29:502-513.
9. Ten Have-Opbroek The development of lung in mammals: an analysis of concepts and findings. Am J Anat. 1981, 162:201-219.
10. Spooner BS, Wessels NK Mammalian lung development: interactions in primordium formation and bronchial morphogenesis. J. Exp. Zool. 1970, 175:445-454.
11. DeMello D, Sawyer D, Galvin N, et al. Early fetal development of lung vasculature. Am. J. Resp. Cell Mol. Biol. 1997, 16:568-581.
12. Lazzaro D, Price M, de Felice M, et al. The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the fetal brain. Development 1991, 113:1093-1104.
13. Minoo P, Su G, Drum H, et al. Defects in tracheoesophageal and lung morphogenesis in Nkx2.1(-/-) mouse embryos. Dev. Biol. 1999, 209:60-71.
14. Kimura S, Ward JM, Minoo P Thyroid-specific enhancer-binding protein/thyroid transcription factor 1 is not required for the initial specification of the thyroid and lung primordia. Biochimie 1999, 81:321-327.
15. Chambon P A decade of molecular biology of retinoic acid receptors. FASEB J 1996, 10:940-954.
16. Niederreither K, McCaffery P, Drager U, et al. Restricted expression and retinoic-induced downregulation of the retinaldehyde dehydrogenase type 2 (RALDH-2) gene during mouse development. Mech. Dev. 1997, 62:67-78.
17. Niederreither K, Subbarayan V, Dolle P, et al. Embryonic retinoic acid synthesis is essential for early mouse post-implantation development. Nat. Genet. 1999, 21:444-448.
18. Zhao D, McCaffery P, Ivins KJ, et al. Molecular identification of a major retinoic acid-synthesizing enzyme: a retinaldehyde-specific dehydrogenase. Eur. J. Biochem. 1996, 240:15-22.
19. Kastner P, Mark M, Ghyselinck N, et al. Genetic evidence that the retinoid signal is transduced by heterodimeric RXR/RAR functional units during mouse development. Development 1997, 124:313-326.
20. Dolle P, Ruberte E, Leroy P, et al. Retinoic acid receptors and cellular retinoid binding proteins. I. A systematic study of their differential pattern of transcription during mouse organogenesis. Development 1990, 110:1133-1151.
21. Mollard R, Viville S, Ward SJ, et al. Tissue-specific expression of retinoic acid receptor isoform transcripts in the mouse embryo. Mech. Dev. 2000, 94:223-232.
22. Malpel SM, Mendelsohn C, Cardoso WV Regulation of retinoic acid signalling during lung morphogenesis. Development 2000, 127:3057-3067.
23. Dickman ED, Thaller C, Smith SM Temporally regulated retinoic acid depletion produces specific neural crest, ocular and nervous defects. Development 1997, 124:3111-3121.
24. Mollard R, Ghyselinck NB, Wendling O, et al. Stage-dependent responses of the developing lung to retinoic acid signalling. Int. J Dev. Biol. 2000, 44:457-462.
25. Mendelsohn C, Lohnes D, Decimo D, et al. Function of retinoic acid receptors (RNRs) during development. II. Multiple abnormalities at various stages of organogenesis in RAR double mutants. Development 1994, 120:2749-2771.
26. Ang S-L, Rossant J HNF-3 is essential for node and notochord formation in mouse development. Cell 1994, 78:561-574.
27. Stahlman MT, Gray ME, Whitsett JA Temporal-spatial distribution of hepatocyte nuclear factor-3beta in developing human lung and other foregut derivatives. J. Histochem. Cytochem. 1998, 46:955-962.
28. Hui C-C, Slusarski D, Platt KA, et al. Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development. Dev. Biol. 1994, 162:402-413.
29. Grindley JC, Bellusci S, Perkins D, et al. Evidence for the involvement of the Gli gene family in embryonic mouse lung development. Dev. Biol. 1997, 188:337-348.
30. Motoyama J, Liu J, Mo R, et al. Essential function of Gli2 and Gli2 in the formation of lung, trachea and oesophagus. Nature Genet. 1998, 20:54-57.
31. Pepicelli CV, Lewis P, McMahon A Sonic hedgehog regulates branching morphogenesis in the mammalian lung. Cur. Biol. 1998, 8:1083-1086.
32. Sekine K, Ohuchi H, Fujiwara M, et al. Fgf-10 is essential for limb and lung formation. Nature Genet. 1999, 21:138-141.
33. De Moerlooze L, Spencer-Dene B, Revest J-M, et al. An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis. Development 2000, 127:483-492.
34. Orr-Urtreger A, Bedford MT, Burakova T, et al. Developmental localization of the splicing alternatives of fibroblast growth factor receptor-2 (FGFR2). Dev. Biol. 1993, 158:475-486.
35. Bellusci S, Grindley J, Emoto H, et al. Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung. Development 1997, 124:4867-4878.
36. Park WY, Miranda B, Lebeche D, et al. FGF-10 is a chemotactic factor for distal epithelial buds during lung development. Dev. Biol. 1998, 201:125-134.
37. Weaver M, Dunn NR, Hogan BL Bmp-4 and Fgf10 play opposing roles during lung bud morphogenesis. Development 2000, 127:2695-2704.
38. Ohuchi H, Hori Y, Yamasaki M, et al. FGF10 acts as a major ligand for FGF receptor 2 IIIb in mouse multi-organ development. Biochem. Biophys. Res. Commun. 2000, 277:643-649.
39. Sutliff KS, Hutchins GM Septation of the respiratory and digestive tracts in human embryos: crucial role of the tracheosophageal sulcus. Anat. Rec. 1994, 238:237-247.
40. Zaw-Tun HA The tracheosophageal septum-Fact or fantasy?. Acta Anat. 1982, 114:1-21.
41. Zhou, Hutson JM, Parmer PJ, Hasthorpe S, et al. Apoptosis in tracheosophageal embryogenesis in rat embryos with or without adriamycin treatment. J Pediatr. Surg. 1999, 34:872-875.
42. Landing BH, Dixon LG Congental malformations and genetic disorders of the respiratory tract (larynx, trachea, bronchi and lungs. Am. Rev. Respir. Dis. 1979, 120:151-185.
43. Hogan BLM Morphogenesis. Cell 1999, 96:225-233.
44. Shannon JM Induction of alveolar type II cell differentiation in fetal tracheal epithelium by grafted distal, lung mesenchyme. Dev. Biol. 1994, 166:600-614.
45. Szebenyi G, Fallon JF Fibroblast growthy factors, as multifunctional signalling factors. Int. Rev. Cytol. 1999, 185:45-106.
46. Sutherland D, Samakovlis C, Krasnow MA Breathless encodes a Drosophila FGF homolog that controls tracheal cell migration and the pattern of branching. Cell 1996, 87:1091-1101.
47. Cardoso WV, Ito A, Nogawa H, et al. FGF-1 and FGF-7 induce distinct patterns of growth and differentiation in embryonic lung epithelium. Dev. Dyn. 1997, 208:398-405.
48. Lebeche D, Malpel S, Cardoso WV Fibroblasts growth factor interactions in the developing lung. Mech. Dev. 1999, 86:125-136.
49. Bellusci S, Furuta Y, Rush MG, et al. Involvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesis. Development 1997, 124:53-63.
50. Hacohen N, Kramer S, Sutherland D, et al. Sprouty encodes, a novel antagonist of FGF signalling that patterns apical branching of the Drosophila airways. Cell 1998, 92:253-263.
51. Minowada G, Jarvis LA, Candace L, et al. Vertebrate sprouty genes are induced by FGF signalling and can cause chondrodysplasia when overexpressed. Development 1999, 126:4465-4475.
52. Tefft DT, Lee M, Smith S, et al. Conserved function of mSpry-2, a murine homolog of Drosophila sprouty, which negatively modulates respiratory organogenesis. Current Biol. 1999, 9:219-222.
53. DeMaximy AA, Nakatake Y, Moncada S, et al. Cloning and expression pattern of a mouse homologue of Drosophila sprouty in the mouse embryo. Mech. Dev. 1999, 81:213-216.
54. Mailleux AA, Tefft D, Ndiaye D, et al. Evidence that SPROUTY2 functions as an inhibitor of mouse embryonic lung growth and morphogenesis. Mech Dev. 2001, 102:81-94.
55. Bellusci S, Henderson R, Winnier G, et al. Evidence from normal expression and targeted misexpression that bone morphogenetic protein-4 (Bmp-4) plays a role in mouse embryonic lung morphogenesis. Development 1996, 122:1693-1702.
56. Weaver M, Yingling JM, Dunn NR, et al. Bmp signalling regulates proximal-distal differentiation of endoderm in mouse lung development. Development 1999, 126:4005-4015.
57. Massague J, Chen YG Controlling TGF signalling. Genes Dev. 2000, 14:627-644.
58. Brunet LJ, McMahon JA, McMahon AP, et al. Noggin, cartilage, morphogenesis, and joint formation in the mammalian skeleton. Science 1998, 280:1455-1457.
59. Heine UI, Munoz EF, Flanders KC, et al. Colocalization of TGF-β1 and collagen I and III, fibronectin, and glycosaminoglycans during lung branching morphogenesis. Development 1990, 109:29-36.
60. Serra R, Moses HL pRb is necessary for inhibition of N-myc expression by TGF-1 in embryonic lung organ cultures. Development 1995, 121:3057-3066.
61. Cardoso WV, Williams MC, Mitsialis SA, et al. Retinoic, acid induces changes in the pattern of airway branching and alters epithelial cell differentiation in the developing lung in vitro. Am. J. Respir. Cell Mol. Biol. 1995, 12:464-476.
62. Cardoso WV, Mitsialis SA, Brody JS, et al. Retinoic acid alters the expression of pattern-related genes in the developing rat lung. Dev. Dyn. 1996, 207:47-59.
63. Lewis EB A gene complex controlling segmentation in Drosophila. Nature 1978, 276:565-570.
64. Kappen C Hox genes in the lung. Am. J. Respir. Cell Mol. Biol. 1996, 15:156-162.
65. Aubin J, Lemieux M, Tremblay M, et al. Early postnatal lethality in Hoxa-5 mutant mice is attributable to respiratory tract defects. Dev. Biol. 1997, 192:432-445.
66. Mercola M, Levin M Left-right asymmetry determination in vertebrates. Annu. Rev. Cell Dev. Biol. 2002, 17:779-805.
67. Meno C, Shimono A, Saijoh Y, et al. Lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal. Cell 1998, 94:287-297.
68. Tsukui T, Capdevila J, Tamura K, et al. Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a conver-gence of the Shh and retinoic acid pathways in the control of Lefty-1. Proc. Natl. Acad. Sci. USA 1999, 96:11376-11381.
69. Suk OP, Li E The signalling pathway mediated by the type IIB activin receptor controls axial patterning and lateral asymmetry in the mouse. Genes Dev. 1997, 11:1812-1826.
70. Wert S, Glasser SW, Korfhagen TR, et al. Transcriptional elements from the human SP-C gene direct expression in the primordial respiratory epithelium of transgenic mice. Dev. Biol. 1993, 156:426-443.
71. Wuenschell CW, Sunday ME, Singh G, et al. Embryonic mouse lung epithelial progenitor cells co-express immunohistochemical markers of diverse mature cell lineages. J. Histochem. Cytochem. 1996, 44:113-123.
72. Botas C, Poulain F, Akiyama J, et al. Altered surfactant homostasis and alveolar type II cell morphology in mice lacking surfactant protein D. Proc. Natl. Acad. Sci. USA 1998, 9:11869-11874.
73. Zhou L, Lim L, Costa RH, et al. Thyroid transcription factor-1, hepatocyte nuclear factor-3beta, surfactant protein B, C, and Clara cell secretory protein in developing mouse lung. J. Histochem. Cytochem. 1996, 44:1183-1193.
74. Williams MC, Cao Y, Hinds A, et al. T1 alpha protein is developmentally regulated and expressed by alveolar type I cells choroid plexus, and ciliary epithelia of adult rats. Am. J. Respir. Cell. Mol. Biol. 1996, 14:577-585.
75. Borok Z, Lubman RL, Danto SI, et al. Keratinocyte growth factor modulates alveolar epithelial cell phenotype in vitro: expression of aquaporin 5. Am. J. Repir. Cell Mol. Biol. 1998, 18:554-561.
76. Borok Z, Danto SI, Lubman RL, et al. Modulation of tlalpha expression with alveolar epithelial cell phenotype in vitro. Am. J. Physiol. 1998, 275:L155-L164.
77. Perl A-KT, Whitsett JA Molecular mechanisms controlling lung morphogenesis. Clin. Genet. 1999, 56:14-27.
78. Zhou LJ, Dey C, Wert SE, et al. Arrested lung morphogenesis in transgenic mice bearing an SP-C-TGF-1 chimeric gene. Dev. Biol. 1996, 175:227-238.
79. Hackett BB, Brody SL, Liang M, et al. Primary structure of hepatocyte nuclear factor/forkhead homologue 4 and characterization of gene expression in the developing respiratory system and reproductive epithelium. Proc. Natl. Acad. Sci. 1995, 92:4249-4253.
80. Chen J, Knowles HJ, Hebert JL, et al. Mutation of the mouse hepatocyte nuclear factor/forkhead homologue 4 gene results in an absence of cilia and random left-right asymmetry. J. Clin. Invest. 1998, 102:1077-1082.
81. Tichelaar JW, Lim L, Costa RH, et al. HNF3/forkhead homologue-4 influences lung morphogenesis and respiratory epithelial cell differentiation in vivo. Dev. Biol. 1999, 213:405-417.
82. Nord M, Cassel TN, Braun H, et al. Regulation of the Clara cell secretory protein/uteroglobin promoter in lung. Ann. NY Acad. Sci. 2000, 923:154-165.
83. Bostrom H, Willetts K, Pekny M, et al. PDGF-A signalling is a critical event in lung alveolar myofibroblast development and alveogenesis. Cell 1996, 85:863-873.
84. Weinstein M, Xu X, Ohyama K, et al. FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung. Development 1998, 125:3615-3623.
85. Tschanz SA, Damke BM, Burri PH Influence of postnatally administered glucocorticoids on rat lung growth. Biol. Neonate 1995, 68:229-245.
86. Massaro GD, Massaro D Retinoic acid treatment partially rescues failed septation in rats and in mice. Am. J Physiol. 2000, 278:L955-L960.
87. Holgate ST, Davies DE, Lackie PM, et al. Epithelial-mesenchymal interactions in the pathogenesis of asthma. J. Allerg. Clin. Immunol. 2000, 105:193-204.
88. Echelard Y, Epstein DJ, St-Jacques B, et al. Sonic hedgehog, a member of a family of putative signalling molecules, is implicated in the regulation of CNS polarity. Cell 1993, 75:1417-1430.
89. Gebert JF, Moghal N, Frangioni JV, et al. High frequency of retinoic acid receptor beta abnormalities in human lung cancer. Oncogene 1991, 6:1859-1868.