Environmental Toxicants and Lung Development in Experimental Models

The Lung: Development, Aging and The Environment

Volumn , Issue , 2004, Pages 345-351

  Fanucchi, Michelle V ^a   Plopper, Charles G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84942248757     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012324751-3/50059-0     Document Type: Chapter

References (107)

1. Ji CM, Royce FH, Truong U, et al. Maternal exposure to environmental tobacco smoke alters Clara cell secretory protein expression in fetal rat lung. Am. J. Physiol. 1998, 275:L870-L876.
2. Lee CZ, Royce FH, Denison MS, et al. Effect of in utero and postnatal exposure to environmental tobacco smoke on the developmental expression of pulmonary cytochrome P450 monooxygenases. J. Biochem. Mol. Toxicol. 2000, 14:121-130.
3. Ji CM, Plopper CG, Witschi HP, et al. Exposure to sidestream cigarette smoke alters bronchiolar epithelial cell differentiation in the postnatal rat lung. Am. J. Respir. Cell Mol. Biol. 1994, 11:312-320.
4. Sindhu RK, Rasmussen RE, Kikkawa Y Effect of environmental tobacco smoke on the metabolism of (-)-trans-benzo[a]pyrene-7,8-dihydrodiol in juvenile ferret lung and liver. J. Toxicol. Environ. Health 1995, 45:453-464.
5. Uejima Y, Fukuchi Y, Nagase T, et al. Influences of tobacco smoke and vitamin E depletion on the distal lung of weanling rats. Exp. Lung Res. 1995, 21:631-642.
6. Mutoh T, Bonham AC, KOtt KS, et al. Chronic exposure to sidestream tobacco smoke augments lung C-fiber responsiveness in young guinea pigs. J. Appl. Physiol. 1999, 87:757-768.
7. Mutoh T, Joad JP, Bonham AC Chronic passive cigarette smoke exposure augments bronchopulmonary C-fibre inputs to nucleus tractus solitarii neurones and reflex output in young guinea-pigs. J. Physiol. 2000, 523(Pt 1):223-233.
8. Bonham AC, Chen CY, Mutoh T, et al. Lung C-fiber CNS reflex: role in the respiratory consequences of extended environmental tobacco smoke exposure in young guinea pigs. Environ. Health Perspect. 2001, 109(Suppl. 4):573-578.
9. Joad JP, Pinkerton KE, Bric JM Effects of sidestream smoke exposure and age on pulmonary function and airway reactivity in developing rats. Pediatr. Pulmonol. 1993, 16:281-288.
10. Joad JP, Bric JM, Peake JL, et al. Perinatal exposure to aged and diluted sidestream cigarette smoke produces airway hyperresponsiveness in older rats. Toxicol. Appl. Pharmacol. 1999, 155:253-260.
11. Slotkin TA, Pinkerton KE, Seidler FJ Perinatal exposure to environmental tobacco smoke alters cell signaling in a primate model: autonomic receptors and the control of adenylyl cyclase activity in heart and lung. Brain Res. Dev. Brain Res. 2000, 124:53-58.
12. Plopper CG, Weir AJ, Morin D, et al. Postnatal changes in the expression and distribution of pulmonary cytochrome P450 monooxygenases during Clara cell differentiation in rabbits. Mol. Pharmacol. 1993, 44:51-61.
13. Plopper CG, Suverkropp C, Morin D, et al. Relationship of cytochrome P-450 activity to Clara cell cytotoxicity. I. Histopathologic comparison of the respiratory tract of mice, rats and hamsters after parenteral administration of naphthalene. J. Pharmacol. Exp. Ther. 1992, 261:353-363.
14. Buckpitt A, Buonarati M, Avey LB, et al. Relationship of cytochrome P450 activity to Clara cell cytotoxicity. II. Comparison of stereoselectivity of naphthalene epoxidation in lung and nasal mucosa of mouse, hamster, rat and rhesus monkey. J. Pharmacol. Exp. Ther. 1992, 261:364-372.
15. Verschoyle RD, Carthew P, Wolf CR, et al. 1-Nitronaphthalene toxicity in rat lung and liver: effects of inhibiting and inducing cytochrome P450 activity. Toxicol. Appl. Pharmacol. 1993, 122:208-213.
16. Boyd MR, Reznik-Schuller HM Metabolic basis for the pulmonary Clara cell as a target for pulmonary carcinogenesis. Toxicol. Pathol. 1984, 12:56-61.
17. Ogawa T, Tsubakihara M, Ichikawa M, et al. An autoradiographic study of the renewal of mouse bronchiolar epithelium following bromobenzene exposure. Toxicol. Pathol. 1993, 21:547-553.
18. Johnson DE, Riley MG, Cornish HH Acute target organ toxicity of 1-nitronaphthalene in the rat. J. Appl. Toxicol. 1984, 4:253-257.
19. Rasmussen RE, Do DH, Kim TS, et al. Comparative cytotoxicity of naphthalene and its monomethyl- and mononitroderivatives in the mouse lung. J. Appl. Toxicol. 1986, 6:13-20.
20. Forkert PG, Birch DW Pulmonary toxicity of trichloroethylene in mice. Covalent binding and morphological manifestations. Drug Metab. Dispos. 1989, 17:106-113.
21. Paige R, Wong V, Plopper C Dose-related airway-selective epithelial toxicity of 1-nitronaphthalene in rats. Toxicol. Appl. Pharmacol. 1997, 147:224-233.
22. O'Brien KA, Smith LL, Cohen GM Differences in naphthalene-induced toxicity in the mouse and rat. Chem-Biol. Int. 1985, 55:109-122.
23. Plopper CG, Weir AJ, Nishio SJ Elevated susceptibility to 4-ipomeanol cytotoxicity in immature Clara cells of neonatal rabbits. J. Pharmacol. Exp. Ther. 1994, 269:867-880.
24. Smiley-Jewell SM, Liu FJ, Weir AJ Acute injury to differentiating Clara cells in neonatal rabbits results in age-related failure of bronchiolar repair. Toxicol. Pathol. 2000, 28:267-276.
25. Fanucchi MV, Buckpitt AR, Murphy ME, et al. Naphthalene cytotoxicity in the differentiating Clara cells of neonatal mice. Toxicol. Appl. Pharmacol. 1997, 144:96-104.
26. Fanucchi MV, Murphy ME, Buckpitt AR, et al. Pulmonary cytochrome P450 monooxygenase and Clara cell differentiation in mice. Am. J. Respir. Cell Mol. Biol. 1997, 17:302-314.
27. Faustman-Watts E, Giachelli C, Juchau M Carbon monoxide inhibits monooxygenation by the conceptus and embryotoxic effects of proteratogens in vitro. Toxicol. Appl. Pharmacol. 1986, 83:590-595.
28. Faustman-Watts E, Namkung M, Juchau M Modulation of the embryotoxicity in vitro of reactive metabolites of 2-acetylaminofluorence by reduced glutathione and ascorbate and via sulfation. Toxicol. Appl. Pharmacol. 1986, 86:400-410.
29. Filler R, Lew KJ Developmental onset of mixed-function oxidase activity in preimplantation mouse embryos. Proc. Natl. Acad. Sci. USA 1981, 78:6991-6995.
30. Galloway SM, Perry PE, Meneses J, et al. Cultured mouse embryos metabolize benzo[a]pyrene during early gestation: genetic differences detectable by sister chromatid exchange. Proc. Natl. Acad. Sci. USA 1980, 77:3524-3528.
31. Juchau MR, Giachelli CM, Fantel AG, et al. Effects of 3-methylcholanthrene and phenobarbital on the capacity of embryos to bioactivate teratogens during organogenesis. Toxicol. Appl. Pharmacol. 1985, 80:137-146.
32. Juchau MR Bioactivation in chemical teratogenesis. Annu. Rev. Pharmacol. Toxicol. 1989, 29:165-187.
33. Palmer KC Clara cell adenomas of the mouse lung. Interaction with alveolar type 2 cells. Am. J. Pathol. 1985, 120:455-463.
34. Yang HY, Namkung MJ, Juchau MR Immunodetection, immunoinhibition, immunoquantitation and biochemical analyses of cytochrome P-450IA1 in tissues of the ratoffceptus during the progression of organogenesis. Biochem. Pharmacol. 1989, 38:4027-4036.
35. Eriksson C, Brittebo EB Dichlobenil in the fetal and neonatal mouse olfactory mucosa. Toxicology 1995, 96:93-104.
36. Forkett PG, Dowsley TF, Lee RP, et al. Differential formation of 1,1-dichloroethylene-metabolites in the lungs of adult and weanling male and female mice: correlation with severities of bronchiolar cytotoxicity. J. Pharmacol. Exp. Ther. 1996, 279:1484-1490.
37. Fanucchi MV, Buckpitt AR, Murphy ME, et al. Development of phase II xenobiotic metabolizing enzymes in differentiating murine clara cells. Toxicol. Appl. Pharmacol. 2000, 168:253-267.
38. Das RM, Scott JE Trichloroethylene-induced pneumotoxicity in fetal and neonatal mice. Toxicol. Lett. 1994, 73:227-239.
39. Turusov VS, Nikonova TV, Parfenov Y Increased multiplicity of lung adenomas in five generations of mice treated with benz(a)pyrene when pregnant. Cancer Lett. 1990, 55:227-231.
40. Frank L, Bucher JR, Roberts RJ Oxygen toxicity in neonatal and adult animals of various species. Am. Physiol. Soc. 1978, 45(5):699-704.
41. Hoffman M, Stevens JB, Autor AP Adaptation to hyperoxia in the neonatal rat: kinetic parameters of the oxygen-mediated induction of lung superoxide dismutases, catalase and glutathione peroxidase. Toxicology 1980, 16:215-225.
42. Stevens JB, Autor AP Proposed mechanism for neonatal rat tolerance to normobaric hyperoxia. Fed. Proc. 1980, 39:3138-3143.
43. Dennery PA, Rodgers PA, Lum MA, et al. Hyperoxic regulation of lung heme oxygenase in neonatal rats. Pediatr. Res. 1996, 40:815-821.
44. Kim HS, Kang SW, Rhee SG, et al. Rat lung peroxiredoxins I and II are differentially regulated during development and by hyperoxia. Am. J. Physiol. Lung Cell Mol. Physiol. 2001, 280:L1212-L1217.
45. Yang G, Madan A, Dennery PA Maturational differences in hyperoxic AP-1 activation in rat lung. Am. J. Physiol. Lung Cell Mol. Physiol. 2000, 278:L393-L398.
46. Bartlett DJ, Faulkner CS, Cook K Effect of chronic ozone exposure on lung elasticity in young rats. J. Appl. Physiol. 1974, 37(1):92-96.
47. Frank L Developmental aspects of experimental pulmonary oxygen toxicity. Free Radic. Biol. Med. 1991, 11:463-494.
48. Bucher JR, Roberts RJ The development of the newborn rat lung in hyperoxia: a dose-response study of lung growth, maturation, and changes in antioxidant enzyme activities. Pediatr. Res. 1981, 15:999-1008.
49. Bonuccelli CM, Permutt S, Sylvester JT Developmental differences in catalase activity and hypoxic-hyperoxic effects on fluid balance in isolated lamb lungs. Pediatr. Res. 1993, 33:519-526.
50. Kennedy KA, Lane NL Effect of in vivo hyperoxia on the glutathione system in neonatal rat lung. Exp. Lung Res. 1994, 20:73-83.
51. Warshaw JB, Wilson CWD, Saito K, et al. The responses of glutathione and antioxidant enzymes to hyperoxia in developing lung. Pediatr. Res. 1985, 19:819-823.
52. Langley SC, Kelly FJ Depletion of pulmonary glutathione using diethylmaleic acid accelerates the development of oxygen-induced lung injury in term and preterm guinea-pig neonates. J. Pharm. Pharmacol. 1993, 46:98-102.
53. Frank L, Groseclose E Oxygen toxicity in newborn rats: the adverse effects of undernutrition. Am. Physiol. Soc. 1982, 53(5):1248-1255.
54. Chessex P, Lavoie JC, Laborie S, et al. Survival of guinea pig pups in hyperoxia is improved by enhanced nutritional substrate availability for glutathione production. Pediatr. Res. 1999, 46:305-310.
55. 2 exposure. Pediatr. Res. 1992, 32:215-221.
56. Sosenko JR, Chen Y, Price LT, et al. Failure of premature rabbits to increase lung antioxidant enzyme activities after hyperoxic exposure: antioxidant enzyme gene expression and pharmacologic intervention with endotoxin and dexamethasone. Pediatr. Res. 1995, 37:469-475.
57. Barnard JA, Lyons RM, Moses HL The cell biology of transforming growth factor b. Biochim. Biophys. Acta Res. Cancer 1990, 1032:79-87.
58. Bartlett D Postnatal growth of the mammalian lung: Influence of low and high oxygen tensions. Respir. Physiol. 1970, 9:58-64.
59. Burri PH, Weibel ER Ultrastructure and Morphometry of the Developing lung. Development of the Lung. Lung Biology in Health and Disease 1977, 215-268. Marcel Dekker, New York. W.A. Hodson (Ed.).
60. Koppel R, Han RNN, Cox D, et al. α1-Antitrypsin protects neonatal rats from pulmonary vascular and parenchymal effects of oxygen toxicity. Pediatr. Res. 1994, 36:763-770.
61. Massaro GD, Olivier J, Massaro D Brief perinatal hypoxia impairs postnatal development of the bronchiolar epithelium. Am. J. Physiol. 1989, 257:L80-L85.
62. 2-induced inhibition of lung septation. Am. J. Physiol. Lung Cell Mol. Physiol. 2002, 283:L971-L980.
63. Veness-Meehan KA, Bottone FG, Stiles AD Effects of retinoic acid on airspace development and lung collagen in hyperoxia-exposed newborn rats. Pediatr. Res. 2000, 48:434-444.
64. Keeney SE, Mathews MJ, Haque AK, et al. Comparison of pulmonary neutrophils in the adult and neonatal rat after hyperoxia. Pediatr. Res. 1995, 38:857-863.
65. Auten RL, Mason SN, Tanaka DT, et al. Anti-neutrophil chemokine preserves alveolar development in hyperoxia-exposed newborn rats. Am. J. Physiol. Lung Cell Mol. Physiol. 2001, 281:L336-L344.
66. Auten RL, Whorton MH, Nicholas Mason S Blocking neutrophil influx reduces DNA damage in hyperoxia-exposed newborn rat lung. Am. J. Respir. Cell Mol. Biol. 2002, 26:391-397.
67. Manji JS, O'Kelly CJ, Leung WI, et al. Timing of hyperoxic exposure during alveolarization influences damage mediated by leukotrienes. Am. J. Physiol. Lung Cell Mol. Physiol. 2001, 281:L799-L806.
68. McGrath-Morrow SA, Stahl J Apoptosis in neonatal murine lung exposed to hyperoxia. Am. J. Respir. Cell Mol. Biol. 2001, 25:150-155.
69. Barry BE, Miller FJ, Crapo JD Effects of inhalation of 0.12 and 0.25 parts per million ozone on the proximal alveolar region of juvenile and adult rats. Lab. Invest. 1985, 53:692-704.
70. Elsayed NM, Mustafa MG, Postlethwait EM Age-dependent pulmonary response of rats to ozone exposure. J. Toxicol. Environ. Health 1982, 9:835-848.
71. 2 exposure. Am. J. Pathol. 1978, 93:183-200.
72. 3-exposed rat lungs. Arch. Environ. Health 1982, 37:167-176.
73. Raub JA, Mercer RR, Kevlock RJ Effects of prenatal nitrofen exposure on postnatal lung function in the rat. Toxicol. Appl. Pharmacol. 1983, 94:119-134.
74. Stiles J, Tyler WS Age-related morphometric differences in responses of rat lungs to ozone. Toxicol. Appl. Pharmacol. 1988, 92:274-285.
75. Tyler WS, Tyler NK, Magliano DJ, et al. Effects of ozone inhalation on lungs of juvenile monkeys. Morphometry after a 12 month exposure and following a 6 month post-exposure. Tropospheric Ozone and the Environment 1990, 152-159. Air & Waste Management Association, Pittsburg, PA. R.L. Berglund, D.R. Lawson, D.J. McKee (Eds.).
76. Mariassy AT, Sielczak MW, McCray MN, et al. Effects of ozone on lamb tracheal mucosa. Quantitative glycoconjugate histochemistry. Am. J. Pathol. 1989, 135:871-879.
77. Shore SA, Abraham JH, Schwartzman IN, et al. Ventilatory responses to ozone are reduced in immature rats. J. Appl. Physiol. 2000, 88:2023-2030.
78. Bunt JE, Carnielli VP, Darcos Wattimena JL, et al. The effect in premature infants of prenatal corticosteroids on endogenous surfactant synthesis as measured with stable isotopes. Am. J. Respir. Crit. Care Med. 2000, 162:844-849.
79. Bancalari E Corticosteroids and neonatal chronic lung disease. Eur. J. Pediatr. 1998, 157(Suppl. 1):S31-S37.
80. National Asthma Education and Prevention Program Expert Panel Report: Guidelines for the Diagnosis and Management of Asthma Update on Selected Topics. J. Allergy Clin. Immunol. 2002, 110:S141-S219.
81. Kay HH, Bird IM, Coe CL, et al. Antenatal steroid treatment and adverse fetal effects: what is the evidence. J. Soc. Gynecol. Invest. 2000, 7:269-278.
82. Moss TJ, Harding R, Newnham JP Lung function, arterial pressure and growth in sheep during early postnatal life following single and repeated prenatal corticosteroid treatments. Early Hum. Dev. 2002, 66:11-24.
83. Willet KE, Jobe AH, Ikegami M, et al. Antenatal endotoxin and glucocorticoid effects on lung morphometry in preterm lambs. Pediatr. Res. 2000, 48:782-788.
84. Walther FJ, Ikegami M, Warburton D, et al. Corticosteroids, thyrotropin-releasing hormone, and antioxidant enzymes in preterm lamb lungs. Pediatr. Res. 1991, 30:518-521.
85. Walther FJ, David-Cu R, Mehta EI, et al. Higher lung antioxidant enzyme activity persists after single dose of corticosteroids in preterm lambs. Am. J. Physiol. 1996, 271:L187-L191.
86. Willet KE, Jobe AH, Ikegami M, et al. Pulmonary interstitial emphysema 24 hours after antenatal betamethasone treatment in preterm sheep. Am. J. Respir. Crit. Care Med. 2000, 162:1087-1094.
87. Tschanz SA, Haenni B, Burri PH Glucocorticoid induced impairment of lung structure assessed by digital image analysis. Eur. J. Pediatr. 2002, 161:26-30.
88. Tschanz SA, Damke BM, Burri PH Influence of postnatally administered glucocorticoids on rat lung growth. Biol. Neonate 1995, 68:229-245.
89. Okajima S, Matsuda T, Cho K, et al. Antenatal dexamethasone administration impairs normal postnatal lung growth in rats. Pediatr. Res. 2001, 49:777-781.
90. Mitzner W, Johnson JW, Beck J, et al. Influence of betamethasone on the development of mechanical properties in the fetal rhesus monkey lung. Am. Rev. Respir. Dis. 1982, 125:233-238.
91. Edwards LA, Read LC, Nishio SJ Comparison of the distinct effects of epidermal growth factor and betamethasone on the morphogenesis of the gas exchange region and differentiation of alveolar type II cells in lungs of fetal rhesus monkeys. J. Pharmacol. Exp. Ther. 1995, 274:1025-1032.
92. Bunton TE, Plopper CG Triamcinolone-induced structural alterations in the development of the lung of the fetal rhesus macaque. Am. J. Obstet. Gynecol. 1984, 148:203-215.
93. Bhatt AJ, Amin SB, Chess PR, et al. Expression of vascular endothelial growth factor and Flk-1 in developing and glucocorticoid-treated mouse lung. Pediatr. Res. 2000, 47:606-613.
94. Fayon M, Jouvencel P, Carles D, et al. Differential effect of dexamethasone and hydrocortisone on alveolar growth in rat pups. Pediatr. Pulmonol. 2002, 33:443-448.
95. le Cras TD, Markham NE, Morris KG, et al. Neonatal dexamethasone treatment increases the risk for pulmonary hypertension in adult rats. Am. J. Physiol. Lung Cell Mol. Physiol. 2000, 278:L822-L829.
96. Nagai A, Matsumiya H, Yasui S, et al. Administration of bromodeoxyuridine in early postnatal rats results in lung changes at maturity. Exp. Lung Res. 1993, 19:203-219.
97. Anisimov VN, Osipova G Two-step carcinogenesis induced by neonatal exposure to 5-bromo-2'-deoxyuridine and subsequent administration of urethan in BALB/c mice. Cancer Lett. 1992, 64:75-82.
98. Manson JM Mechanism of nitrofen teratogenesis. Environ. Health Perspect. 1986, 70:137-147.
99. Brown TJ, Manson JM Further characterization of the distribution and metabolism of nitrofen in the pregnant rat. Teratology 1986, 34:129-139.
100. Losada A, Tovar JA, Xia HM, et al. Down-regulation of thyroid transcription factor-1 gene expression in fetal lung hypoplasia is restored by glucocorticoids. Endocrinology 2000, 141:2166-2173.
101. Losada A, Xia H, Migliazza L, et al. Lung hypoplasia caused by nitrofen is mediated by down-regulation of thyroid transcription factor TTF-1. Pediatr. Surg. Int. 1999, 15:188-191.
102. Gosney JR, Okoye BO, Lloyd DA, et al. Pulmonary neuroendocrine cells in nitrofen-induced diaphragmatic hernia and the effect of prenatal glucocorticoids. Pediatr. Surg. Int. 1999, 15:180-183.
103. Branstetter DG, Moseley PP Effect of lung development on the histological pattern of lung tumors induced by ethylnitrosourea in the C3HeB/FeJ mouse. Exp. Lung Res. 1991, 17:169-179.
104. Rehm S, Ward JM, Anderson LM, et al. Transplacental induction of mouse lung tumors: stage of fetal organogenesis in relation to frequency, morphology, size, and neoplastic progression of N-nitrosoethylurea-induced tumors. Toxicol. Pathol. 1991, 19:35-46.
105. Mauceri HJ, Lee WH, Conway S Effect of ethanol on insulin-like growth factor-II release from fetal organs. Alcohol Clin. Exp. Res. 1994, 18:35-41.
106. Mauceri HJ, Becker KB, Conway S The influence of ethanol exposure on insulin-like growth factor (IGF) type II receptors in fetal rat tissues. Life Sci. 1996, 59:51-60.
107. Sosenko IR Antenatal cocaine exposure produces accelerated surfactant maturation without stimulation of antioxidant enzyme development in the late gestation rat. Pediatr. Res. 1993, 33:327-331.