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Volumn 279, Issue 3, 1996, Pages 1484-1490

Differential formation of 1,1-dichloroethylene-metabolites in the lungs of adult and weanling male and female mice: Correlation with severities of bronchiolar cytotoxicity

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; VINYLIDENE CHLORIDE;

EID: 0030425572     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (26)

References (30)
  • 1
    • 0022534104 scopus 로고
    • Dimethylnitrosamine metabolism: I. in vitro activation of dimethylnitrosamine to mutagenic substance(s) by hepatic and renal tissues from three inbred strains of mice
    • AMPY, F. R. AND WILLIAMS, A. O.: Dimethylnitrosamine metabolism: I. In vitro activation of dimethylnitrosamine to mutagenic substance(s) by hepatic and renal tissues from three inbred strains of mice. Life Sci. 39: 923-930, 1986.
    • (1986) Life Sci. , vol.39 , pp. 923-930
    • Ampy, F.R.1    Williams, A.O.2
  • 2
    • 0028901298 scopus 로고
    • Reaction of glutathione with the electrophilic metabolites of 1,1-dichloroethylene
    • DOWSLEY, T. F., FORKERT, P. G., BENESCH, L. A. AND BOLTON, J. L.: Reaction of glutathione with the electrophilic metabolites of 1,1-dichloroethylene. Chem. Biol. Interact. 96: 227-244, 1995.
    • (1995) Chem. Biol. Interact. , vol.96 , pp. 227-244
    • Dowsley, T.F.1    Forkert, P.G.2    Benesch, L.A.3    Bolton, J.L.4
  • 3
    • 0030200743 scopus 로고    scopus 로고
    • CYP2E1-dependent bioactivation of 1,1-dichloroethylene in murine lung: Formation of reactive intermediates and glutathione conjugates
    • DOWSLEY, T. F., ULREICH, J. B., BOLTON, J. L., PARK, S. S. AND FORKERT, P. G.: CYP2E1-dependent bioactivation of 1,1-dichloroethylene in murine lung: Formation of reactive intermediates and glutathione conjugates. Toxicol. Appl. Pharmacol. 139: 42-48, 1996.
    • (1996) Toxicol. Appl. Pharmacol. , vol.139 , pp. 42-48
    • Dowsley, T.F.1    Ulreich, J.B.2    Bolton, J.L.3    Park, S.S.4    Forkert, P.G.5
  • 4
    • 0029321404 scopus 로고
    • CYP2E1 is preferentially expressed in Clara cells of murine lung: Localization by in situ hybridization and immunohistochemical methods
    • FORKERT, P. G.: CYP2E1 is preferentially expressed in Clara cells of murine lung: Localization by in situ hybridization and immunohistochemical methods. Am. J. Respir. Cell Mol. Biol. 12: 589-596, 1995.
    • (1995) Am. J. Respir. Cell Mol. Biol. , vol.12 , pp. 589-596
    • Forkert, P.G.1
  • 5
    • 0025354245 scopus 로고
    • Morphologic changes and covalent binding of 1,1-dichloroethylene in Clara and alveolar type II cells isolated from lungs of mice following in vivo administration
    • FORKERT, P. G., GEDDES, B. A., BIRCH, D. W. AND MASSEY, T. E.: Morphologic changes and covalent binding of 1,1-dichloroethylene in Clara and alveolar type II cells isolated from lungs of mice following in vivo administration. Drug Metab. Dispos. 18: 534-539, 1990.
    • (1990) Drug Metab. Dispos. , vol.18 , pp. 534-539
    • Forkert, P.G.1    Geddes, B.A.2    Birch, D.W.3    Massey, T.E.4
  • 6
    • 0029985411 scopus 로고    scopus 로고
    • Alterations in expression of CYP1A1 and NADPH-cytochrome P450 reductase during lung tumor development in SWR/J mice
    • FORKERT, P. G., LORD, J. A. AND PARKINSON, A.: Alterations in expression of CYP1A1 and NADPH-cytochrome P450 reductase during lung tumor development in SWR/J mice. Carcinogenesis 17: 127-132, 1996.
    • (1996) Carcinogenesis , vol.17 , pp. 127-132
    • Forkert, P.G.1    Lord, J.A.2    Parkinson, A.3
  • 7
    • 0025755301 scopus 로고
    • 1,1-Dichloroethylene elicits dose-dependent alterations in covalent binding and glutathione in liver
    • FORKERT, P. G. AND MOUSSA, M.: 1,1-Dichloroethylene elicits dose-dependent alterations in covalent binding and glutathione in liver. Drug Metab. Dispos. 19: 580-586, 1991.
    • (1991) Drug Metab. Dispos. , vol.19 , pp. 580-586
    • Forkert, P.G.1    Moussa, M.2
  • 8
    • 0027433172 scopus 로고
    • Temporal effects of 1,1-dichloroethylene on nonprotein sulfhydryl content in murine lung and liver
    • FORKERT, P. G. AND MOUSSA, M.: Temporal effects of 1,1-dichloroethylene on nonprotein sulfhydryl content in murine lung and liver. Drug Metab. Dispos. 21: 770-776, 1993.
    • (1993) Drug Metab. Dispos. , vol.21 , pp. 770-776
    • Forkert, P.G.1    Moussa, M.2
  • 9
    • 0022608880 scopus 로고
    • Pulmonary toxicity of 1,1-dichloroethylene: Correlation of early changes with covalent binding
    • FORKERT, P. G., STRINGER, V. AND TROUGHTON, K. M.: Pulmonary toxicity of 1,1-dichloroethylene: Correlation of early changes with covalent binding. Can. J. Physiol. Pharmacol. 64: 112-121, 1986.
    • (1986) Can. J. Physiol. Pharmacol. , vol.64 , pp. 112-121
    • Forkert, P.G.1    Stringer, V.2    Troughton, K.M.3
  • 10
    • 0026595042 scopus 로고
    • cDNA sequence, deduced amino acid sequence, predicted gene structure and chemical regulation of mouse Cyp2e1
    • FREEMAN, J. E., STIRLING, D., RUSSEL, A. L. AND WOLF, C. R.: cDNA sequence, deduced amino acid sequence, predicted gene structure and chemical regulation of mouse Cyp2e1. Biochem. J. 281: 689-695, 1992.
    • (1992) Biochem. J. , vol.281 , pp. 689-695
    • Freeman, J.E.1    Stirling, D.2    Russel, A.L.3    Wolf, C.R.4
  • 11
    • 0021995437 scopus 로고
    • Major differences in the specificity of renal cytochrome P450-dependent monoxgenases. A comparison of xenobiotic and endogenous substrates
    • HAWKE, R. L. AND WELCH, R. M.: Major differences in the specificity of renal cytochrome P450-dependent monoxgenases. A comparison of xenobiotic and endogenous substrates. Mol. Pharmacol. 28: 283-289, 1985.
    • (1985) Mol. Pharmacol. , vol.28 , pp. 283-289
    • Hawke, R.L.1    Welch, R.M.2
  • 12
    • 0023552965 scopus 로고
    • Regulation of N-nitrosodimethylamine demethylase in rat liver and kidney
    • HONG, J.-H., PAN, J., DONG, Z., NING, S. M. AND YANG, C. S.: Regulation of N-nitrosodimethylamine demethylase in rat liver and kidney. Cancer Res. 47: 5948-5953, 1987.
    • (1987) Cancer Res. , vol.47 , pp. 5948-5953
    • Hong, J.-H.1    Pan, J.2    Dong, Z.3    Ning, S.M.4    Yang, C.S.5
  • 13
    • 0024383652 scopus 로고
    • Molecular basis for the sex-related difference in renal N-nitrosodimethylamine demethylase in C3H/HeJ mice
    • HONG, J.-H., PAN, J., NING, S. M. AND YANG, C. S.: Molecular basis for the sex-related difference in renal N-nitrosodimethylamine demethylase in C3H/HeJ mice. Cancer Res. 49: 2973-2979, 1989.
    • (1989) Cancer Res. , vol.49 , pp. 2973-2979
    • Hong, J.-H.1    Pan, J.2    Ning, S.M.3    Yang, C.S.4
  • 15
    • 0025688981 scopus 로고
    • Mouse renal cytochrome P450: Immunocytochemical localization, sex-related difference and regulation by testosterone
    • HU, J. J., RHOTEN, W. B. AND YANG, C. S.: Mouse renal cytochrome P450: Immunocytochemical localization, sex-related difference and regulation by testosterone. Biochem. Pharmacol. 40: 2597-2602, 1990.
    • (1990) Biochem. Pharmacol. , vol.40 , pp. 2597-2602
    • Hu, J.J.1    Rhoten, W.B.2    Yang, C.S.3
  • 16
    • 77957187616 scopus 로고
    • Effects of 1,1-dichloroethene and some of its metabolites on the functional viability of mouse hepatocytes
    • KAINZ, A., CROSS, H., FREEMAN, S., GESCHER, A. AND CHIPMAN, J. K.: Effects of 1,1-dichloroethene and some of its metabolites on the functional viability of mouse hepatocytes. Fund. Appl. Toxicol. 21: 140-148, 1993.
    • (1993) Fund. Appl. Toxicol. , vol.21 , pp. 140-148
    • Kainz, A.1    Cross, H.2    Freeman, S.3    Gescher, A.4    Chipman, J.K.5
  • 17
    • 0022494453 scopus 로고
    • Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a
    • KOOP, D. R.: Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a. Mol. Pharmacol. 29: 399-404, 1986.
    • (1986) Mol. Pharmacol. , vol.29 , pp. 399-404
    • Koop, D.R.1
  • 18
    • 0028239623 scopus 로고
    • In vitro biotransformation of 1,1-dichloroethylene by hepatic cytochrome P-450 2E1 in mice
    • LEE, R. P. AND FORKERT, P. G.: In vitro biotransformation of 1,1-dichloroethylene by hepatic cytochrome P-450 2E1 in mice. J. Pharmacol. Exp. Ther. 270: 371-376, 1994.
    • (1994) J. Pharmacol. Exp. Ther. , vol.270 , pp. 371-376
    • Lee, R.P.1    Forkert, P.G.2
  • 19
    • 0028926741 scopus 로고
    • Pulmonary CYP2E1 bioactivates 1,1-dichloroethylene in male and female mice
    • LEE, R. P. AND FORKERT, P. G.: Pulmonary CYP2E1 bioactivates 1,1-dichloroethylene in male and female mice. J. Pharmacol. Exp. Ther. 273: 561-567, 1995.
    • (1995) J. Pharmacol. Exp. Ther. , vol.273 , pp. 561-567
    • Lee, R.P.1    Forkert, P.G.2
  • 20
    • 0021934593 scopus 로고
    • Formation of glutathione conjugates by reactive metabolites of vinylidine chloride in microsomes and isolated hepatocytes
    • LIEBLER, D. C., MEREDITH, M. J. AND GUENGERICH, F. P.: Formation of glutathione conjugates by reactive metabolites of vinylidine chloride in microsomes and isolated hepatocytes. Cancer Res. 45: 186-193, 1985.
    • (1985) Cancer Res. , vol.45 , pp. 186-193
    • Liebler, D.C.1    Meredith, M.J.2    Guengerich, F.P.3
  • 22
    • 0019500050 scopus 로고
    • Hormonal regulation of the metabolism of carcinogens in renal tissue of BALB/c mice
    • MOHLA, S., AMPY, F. R., SANDERS, K. J. AND CRISS, W. E.: Hormonal regulation of the metabolism of carcinogens in renal tissue of BALB/c mice. Cancer Res. 41: 3821-3823, 1981.
    • (1981) Cancer Res. , vol.41 , pp. 3821-3823
    • Mohla, S.1    Ampy, F.R.2    Sanders, K.J.3    Criss, W.E.4
  • 23
    • 0023948215 scopus 로고
    • Tissue specific regulation of renal N-nitrosodimethylamine demethylase activity by testosterone in BALB/c mice
    • MOHLA, S., AHIR, S. AND AMPY, F. R.: Tissue specific regulation of renal N-nitrosodimethylamine demethylase activity by testosterone in BALB/c mice. Biochem. Pharmacol. 37: 2697-2702, 1988.
    • (1988) Biochem. Pharmacol. , vol.37 , pp. 2697-2702
    • Mohla, S.1    Ahir, S.2    Ampy, F.R.3
  • 24
    • 0026511385 scopus 로고
    • 1,1-Dichloroethylene-induced alterations in glutathione and covalent binding in murine lung: Morphological, histochemical and biochemical studies
    • MOUSSA, M. AND FORKERT, P. G.: 1,1-Dichloroethylene-induced alterations in glutathione and covalent binding in murine lung: Morphological, histochemical and biochemical studies. J. Pathol. 166: 199-207, 1992.
    • (1992) J. Pathol. , vol.166 , pp. 199-207
    • Moussa, M.1    Forkert, P.G.2
  • 25
    • 0022443227 scopus 로고
    • 14C]1,1-dichloroethylene by mouse liver, kidney and lung
    • 14C]1,1-dichloroethylene by mouse liver, kidney and lung. Biochem. Pharmacol. 35: 2789-2795, 1986.
    • (1986) Biochem. Pharmacol. , vol.35 , pp. 2789-2795
    • Okine, L.K.1    Gram, T.E.2
  • 26
    • 0021674961 scopus 로고
    • Strain and sex differences in chloroform-induced nephrotoxicity
    • POHL, L. R., GEORGE, J. W. AND SATOH, J.: Strain and sex differences in chloroform-induced nephrotoxicity. Drug Metab. Dispos. 12: 304-310, 1984.
    • (1984) Drug Metab. Dispos. , vol.12 , pp. 304-310
    • Pohl, L.R.1    George, J.W.2    Satoh, J.3
  • 27
    • 0028893497 scopus 로고
    • Renal tumorigenicity of 1,1-dichloroethene in mice: The role of male-specific expression of cytochrome P450 2E1 in the renal bioactivation of 1,1-dichloroethene
    • SPEERSCHNEIDER, P. AND DEKANT, W.: Renal tumorigenicity of 1,1-dichloroethene in mice: The role of male-specific expression of cytochrome P450 2E1 in the renal bioactivation of 1,1-dichloroethene. Toxicol. Appl. Pharmacol. 130: 48-56, 1995.
    • (1995) Toxicol. Appl. Pharmacol. , vol.130 , pp. 48-56
    • Speerschneider, P.1    Dekant, W.2
  • 28
    • 0023180336 scopus 로고
    • Regulation of cytochrome P-450j, a high-affinity N-nitrosodimethylamine demethylase, in rat hepatic microsomes
    • THOMAS, P. E., BANDIERA, S., MAINES, S. L., RYAN, D. E. AND LEVIN, W.: Regulation of cytochrome P-450j, a high-affinity N-nitrosodimethylamine demethylase, in rat hepatic microsomes. Biochemistry 26: 2280-2289, 1987.
    • (1987) Biochemistry , vol.26 , pp. 2280-2289
    • Thomas, P.E.1    Bandiera, S.2    Maines, S.L.3    Ryan, D.E.4    Levin, W.5
  • 29
    • 0026319304 scopus 로고
    • Induction, purification, and characterization of cytochrome P450IIE
    • YANG, C. S., PATTEN, C. J., ISHIZAKI, H. AND YOO, J.-S. H.: Induction, purification, and characterization of cytochrome P450IIE. Methods Enzymol. 206: 595-603, 1991.
    • (1991) Methods Enzymol. , vol.206 , pp. 595-603
    • Yang, C.S.1    Patten, C.J.2    Ishizaki, H.3    Yoo, J.-S.H.4
  • 30
    • 0023119110 scopus 로고
    • Metabolism and activation of N-nitrosodimethylamine by hamster and rat microsomes: Comparative study with weanling and adult animals
    • YOO, J.-S. H., NING, S. M., PATTEN, C. J. AND YANG, C. S.: Metabolism and activation of N-nitrosodimethylamine by hamster and rat microsomes: Comparative study with weanling and adult animals. Cancer Res. 47: 992-998, 1987.
    • (1987) Cancer Res. , vol.47 , pp. 992-998
    • Yoo, J.-S.H.1    Ning, S.M.2    Patten, C.J.3    Yang, C.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.