Development of phase II xenobiotic metabolizing enzymes in differentiating murine Clara cells

Toxicology and Applied Pharmacology

Volumn 168, Issue 3, 2000, Pages 253-267

  Fanucchi, Michelle V ^a   Buckpitt, Alan R ^a   Murphy, Mary E ^a   Storms, David H ^a   Hammock, Bruce D ^a   Plopper, Charles G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Epoxide hydrolase; Glutathione S transferase; Lung development

Indexed keywords

DRUG METABOLIZING ENZYME; EPOXIDE HYDROLASE; GLUTATHIONE TRANSFERASE; ISOENZYME;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROTECTION; CLARA CELL; CONTROLLED STUDY; DETOXIFICATION; ENZYME ACTIVITY; FEMALE; GEL ELECTROPHORESIS; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; LUNG DEVELOPMENT; MALE; MICROSOME; MOUSE; NONHUMAN; PROTEIN EXPRESSION; XENOBIOTIC METABOLISM;

ANIMALIA; MURINAE;

EID: 0034329486     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.2000.9020     Document Type: Article

References (50)

1. Developmental regulation of glutathione S-transferases
2. Developmental aspects of hepatic glutathione S-transferase activities in male rats
3. Human glutathione S-transferases: Radioimmunoassay studies on the expression of alpha-, mu- and pi-class isoenzymes in developing lung and kidney
4. Indoor air pollution and pulmonary function growth in preadolescent children
5. Relationship of cytochrome P450 activity to Clara cell cytotoxicity. II. Comparison of stereoselectivity of naphthalene epoxidation in lung and nasal mucosa of mouse, hamster, rat and rhesus monkey
6. Relationship of cytochrome P450 activity to Clara cell cytotoxicity. IV. Metabolism of naphthalene and naphthalene oxide in microdissected airways from mice, rats, and hamsters
7. Metabolism and cytotoxicity of naphthalene and its metabolites in isolated murine Clara cells
8. Characterization of the cytochrome P-450 monooxygenase system in nonciliated bronchiolar epithelial (Clara) cells isolated from mouse lung
9. The alpha and pi isoenzymes of glutathione S-transferase in human fetal lung: In utero ontogeny compared with differentiation in lung organ culture
10. Immunolocalization of antioxidant enzymes and isozymes of glutathione S-transferase in normal rat lung
11. Racial differences in the association between maternal smoking during pregnancy and lung function in children
12. Maternal smoking during pregnancy as a predictor of lung function in children
13. Environmental tobacco smoke, wheezing, and asthma in children in 24 communities
14. Cytochrome P-450 monooxygenase, epoxide hydrolase and ravin monooxygenase activities in Clara cells and alveolar type II cells isolated from rabbit
15. Quantitation of rabbit cytochrome P-450, form 2, in microsomal preparations bound directly to nitrocellulose paper using a modified peroxidase-immunostaining procedure
16. Rates of glutathione synthesis in lung subcompartments of mice and monkeys: Possible role in species and site selective injury
17. Maternal cigarette smoking is associated with increased inner airway wall thickness in children who die from sudden infant death syndrome
18. Pulmonary developmental responses to toxicants
19. Naphthalene cytotoxicity in the differentiating Clara cells of neonatal mice
20. Pulmonary cytochrome P450 monooxygenase and Clara cell differentiation in mice
21. Expression and inducibility of alpha, pi, and mu glutathiorte S-transferase protein and mRNA in murine lung
22. The development of glutathione S-transferase and glutathione peroxidase activities in human lung
23. Radiometric assays for mammalian epoxide hydrolases and glutathione S-transferase
24. Glutathione S-transferases: The first enzymatic step in mercapturic acid formation
25. Antenatal interventions in childhood asthma
26. Pulmonary cytochrome P-450 monooxygenase system and Clara cell differentiation in rats
27. The regulation of hepatic glutathione
28. The effect of passive smoking and tobacco exposure through breast milk on sudden infant death syndrome
29. Immunolocalization of glutathione S-transferase isoenzymes in bronchlolar epithelium of rats and mice
30. Protein measurement with the Folin phenol reagent
31. The isoenzymes of glutathione transferase
32. Glutathione transferases: Structure and catalytic activity
33. Immunohistochemical localization of glutathione-S-transferase and glutathione peroxidase in adult Syrian hamster tissues and during kidney development
34. Developmental expression of human microsomal epoxide hydrolase
35. Metabolism of styrene oxide in different human fetal tissues
36. Relationship of cytochrome P-450 activity to Clara cell cytotoxicity. III. Morphometric comparison of changes in the epithelial populations of terminal bronchioles and lobar bronchi, in mice, hamsters, and rats after parenteral administration of naphthalene
37. Relationship of cytochrome P-450 activity to Clara cell cytotoxicity. I. Histopathologic comparison of the respiratory tract of mice, rats and hamsters after parenteral administration of naphthalene
38. Postnatal changes in the expression and distribution of pulmonary cytochrome P450 monooxygenases during Clara cell differentiation in rabbits
39. Elevated susceptibility to 4-ipomeanol cytotoxicity in immature Clara cells of neonatal rabbits
40. Ontogeny of benzo(a)pyrene hydroxylase, epoxide hydrolase and glutathione-S transferase in the brain, lung and liver of C57B1/6 mice
41. The distribution of cytochrome P-450 monooxygenase in cells of the rabbit lung: An ultrastructural immunocytochemical characterization
42. Quantitation of mRNAs specific for the mixed-function oxidase system in rat liver and extrahepatic tissues during development
43. Acute injury to differentiating Clara cells in neonatal rabbits results in age-related failure of bronchiolar repair
44. Neonatal Clara cell toxicity by 4-ipomeanol alters bronchiolar organization in adult rabbits
45. The human glutathione S-transferases: Developmental aspects of the GST1, GST2, and GST3 loci
46. A longitudinal study of the effects of parental smoking on pulmonary function in children 6-18 years
47. Passive smoking, gas cooking, and respiratory health of children living in six cities
48. The carcinogenic potential of the gas phase of environmental tobacco smoke
49. Membrane-bound and soluble-fraction epoxide hydrolases: Methodological aspects