-
1
-
-
84871969762
-
Largescale association analysis identifies new risk loci for coronary artery disease
-
CARDIoGRAMplusC4D Consortium; DIAGRAM Consortium; CARDIOGENICS Consortium; MuTHER Consortium; Wellcome Trust Case Control Consortium
-
Deloukas P, Kanoni S, Willenborg C, et al; CARDIoGRAMplusC4D Consortium; DIAGRAM Consortium; CARDIOGENICS Consortium; MuTHER Consortium; Wellcome Trust Case Control Consortium. Largescale association analysis identifies new risk loci for coronary artery disease. Nat Genet. 2013;45:25-33. doi: 10. 1038/ng. 2480.
-
(2013)
Nat Genet.
, vol.45
, pp. 25-33
-
-
Deloukas, P.1
Kanoni, S.2
Willenborg, C.3
-
2
-
-
84923342405
-
Genome-wide significant loci: How important are they? Systems genetics to understand heritability of coronary artery disease and other common complex disorders
-
BjÖrkegren JL, Kovacic JC, Dudley JT, Schadt EE. Genome-wide significant loci: how important are they? Systems genetics to understand heritability of coronary artery disease and other common complex disorders. J Am Coll Cardiol. 2015;65:830-845. doi: 10. 1016/j. jacc. 2014. 12. 033.
-
(2015)
J Am Coll Cardiol.
, vol.65
, pp. 830-845
-
-
Björkegren, J.L.1
Kovacic, J.C.2
Dudley, J.T.3
Schadt, E.E.4
-
3
-
-
77955499945
-
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus
-
Musunuru K, Strong A, Frank-Kamenetsky M, et al. From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus. Nature. 2010;466:714-719. doi: 10. 1038/nature09266.
-
(2010)
Nature.
, vol.466
, pp. 714-719
-
-
Musunuru, K.1
Strong, A.2
Frank-Kamenetsky, M.3
-
4
-
-
84905658469
-
Mendelian randomization studies in coronary artery disease
-
Jansen H, Samani NJ, Schunkert H. Mendelian randomization studies in coronary artery disease. Eur Heart J. 2014;35:1917-1924. doi: 10. 1093/ eurheartj/ehu208.
-
(2014)
Eur Heart J.
, vol.35
, pp. 1917-1924
-
-
Jansen, H.1
Samani, N.J.2
Schunkert, H.3
-
5
-
-
84865822182
-
Systematic localization of common disease-associated variation in regulatory DNA
-
Maurano MT, Humbert R, Rynes E, et al. Systematic localization of common disease-associated variation in regulatory DNA. Science. 2012;337:1190-1195. doi: 10. 1126/science. 1222794.
-
(2012)
Science.
, vol.337
, pp. 1190-1195
-
-
Maurano, M.T.1
Humbert, R.2
Rynes, E.3
-
6
-
-
77951439152
-
Traitassociated SNPs are more likely to be eQTLs: Annotation to enhance discovery from GWAS
-
Nicolae DL, Gamazon E, Zhang W, Duan S, Dolan ME, Cox NJ. Traitassociated SNPs are more likely to be eQTLs: Annotation to enhance discovery from GWAS. PLoS Genet. 2010;6:e1000888. doi: 10. 1371/journal. pgen. 1000888.
-
(2010)
PLoS Genet.
, vol.6
, pp. e1000888
-
-
Nicolae, D.L.1
Gamazon, E.2
Zhang, W.3
Duan, S.4
Dolan, M.E.5
Cox, N.J.6
-
7
-
-
84865777825
-
Linking disease associations with regulatory information in the human genome
-
Schaub MA, Boyle AP, Kundaje A, Batzoglou S, Snyder M. Linking disease associations with regulatory information in the human genome. Genome Res. 2012;22:1748-1759. doi: 10. 1101/gr. 136127. 111.
-
(2012)
Genome Res.
, vol.22
, pp. 1748-1759
-
-
Schaub, M.A.1
Boyle, A.P.2
Kundaje, A.3
Batzoglou, S.4
Snyder, M.5
-
8
-
-
84888132259
-
Identifying multiple causative genes at a single GWAS locus
-
Flister MJ, Tsaih SW, O'Meara CC, Endres B, Hoffman MJ, Geurts AM, Dwinell MR, Lazar J, Jacob HJ, Moreno C. Identifying multiple causative genes at a single GWAS locus. Genome Res. 2013;23:1996-2002. doi: 10. 1101/gr. 160283. 113.
-
(2013)
Genome Res.
, vol.23
, pp. 1996-2002
-
-
Flister, M.J.1
Tsaih, S.W.2
O'Meara, C.C.3
Endres, B.4
Hoffman, M.J.5
Geurts, A.M.6
Dwinell, M.R.7
Lazar, J.8
Jacob, H.J.9
Moreno, C.10
-
9
-
-
84929001104
-
Human genomics. The genotype-tissue expression (GTEx) pilot analysis: Multitissue gene regulation in humans
-
Consortium GT. Human genomics. The genotype-tissue expression (GTEx) pilot analysis: Multitissue gene regulation in humans. Science. 2015;348:648-660.
-
(2015)
Science.
, vol.348
, pp. 648-660
-
-
Consortium, G.T.1
-
10
-
-
84858779229
-
HaploReg: A resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants
-
Database issue
-
Ward LD, Kellis M. HaploReg: A resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants. Nucleic Acids Res. 2012;40(Database issue):D930-D934. doi: 10. 1093/nar/gkr917.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. D930-D934
-
-
Ward, L.D.1
Kellis, M.2
-
11
-
-
57249114505
-
SNAP: A web-based tool for identification and annotation of proxy SNPs using HapMap
-
Johnson AD, Handsaker RE, Pulit SL, Nizzari MM, O'Donnell CJ, de Bakker PI. SNAP: A web-based tool for identification and annotation of proxy SNPs using HapMap. Bioinformatics. 2008;24:2938-2939. doi: 10. 1093/bioinformatics/btn564.
-
(2008)
Bioinformatics.
, vol.24
, pp. 2938-2939
-
-
Johnson, A.D.1
Handsaker, R.E.2
Pulit, S.L.3
Nizzari, M.M.4
O'Donnell, C.J.5
De Bakker, P.I.6
-
12
-
-
84891767394
-
RefSeq: An update on mammalian reference sequences
-
Database issue
-
Pruitt KD, Brown GR, Hiatt SM, et al. RefSeq: An update on mammalian reference sequences. Nucleic Acids Res. 2014;42(Database issue):D756-D763. doi: 10. 1093/nar/gkt1114.
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. D756-D763
-
-
Pruitt, K.D.1
Brown, G.R.2
Hiatt, S.M.3
-
13
-
-
84865760395
-
GENCODE: The reference human genome annotation for the ENCODE Project
-
Harrow J, Frankish A, Gonzalez JM, et al. GENCODE: the reference human genome annotation for The ENCODE Project. Genome Res. 2012;22:1760-1774. doi: 10. 1101/gr. 135350. 111.
-
(2012)
Genome Res.
, vol.22
, pp. 1760-1774
-
-
Harrow, J.1
Frankish, A.2
Gonzalez, J.M.3
-
15
-
-
77956534324
-
ANNOVAR: Functional annotation of genetic variants from high-throughput sequencing data
-
Wang K, Li M, Hakonarson H. ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data. Nucleic Acids Res. 2010;38:e164. doi: 10. 1093/nar/gkq603.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. e164
-
-
Wang, K.1
Li, M.2
Hakonarson, H.3
-
16
-
-
84881613239
-
DbNSFP v2. 0: A database of human nonsynonymous SNVs and their functional predictions and annotations
-
Liu X, Jian X, Boerwinkle E. dbNSFP v2. 0: A database of human nonsynonymous SNVs and their functional predictions and annotations. Hum Mutat. 2013;34:E2393-E2402. doi: 10. 1002/humu. 22376.
-
(2013)
Hum Mutat.
, vol.34
, pp. E2393-E2402
-
-
Liu, X.1
Jian, X.2
Boerwinkle, E.3
-
17
-
-
84895858942
-
A general framework for estimating the relative pathogenicity of human genetic variants
-
Kircher M, Witten DM, Jain P, O'Roak BJ, Cooper GM, Shendure J. A general framework for estimating the relative pathogenicity of human genetic variants. Nat Genet. 2014;46:310-315. doi: 10. 1038/ng. 2892.
-
(2014)
Nat Genet.
, vol.46
, pp. 310-315
-
-
Kircher, M.1
Witten, D.M.2
Jain, P.3
O'Roak, B.J.4
Cooper, G.M.5
Shendure, J.6
-
18
-
-
84941053261
-
GRASP v2. 0: An update on the Genome-Wide Repository of Associations between SNPs and phenotypes
-
Database issue
-
Eicher JD, Landowski C, Stackhouse B, Sloan A, Chen W, Jensen N, Lien JP, Leslie R, Johnson AD. GRASP v2. 0: An update on the Genome-Wide Repository of Associations between SNPs and phenotypes. Nucleic Acids Res. 2015;43(Database issue):D799-D804. doi: 10. 1093/nar/gku1202.
-
(2015)
Nucleic Acids Res.
, vol.43
, pp. D799-D804
-
-
Eicher, J.D.1
Landowski, C.2
Stackhouse, B.3
Sloan, A.4
Chen, W.5
Jensen, N.6
Lien, J.P.7
Leslie, R.8
Johnson, A.D.9
-
19
-
-
84923328349
-
Expression quantitative trait loci acting across multiple tissues are enriched in inherited risk for coronary artery disease
-
CARDIoGRAM Consortium
-
Foroughi Asl H, Talukdar HA, Kindt AS, et al; CARDIoGRAM Consortium. Expression quantitative trait loci acting across multiple tissues are enriched in inherited risk for coronary artery disease. Circ Cardiovasc Genet. 2015;8:305-315. doi: 10. 1161/CIRCGENETICS. 114. 000640.
-
(2015)
Circ Cardiovasc Genet.
, vol.8
, pp. 305-315
-
-
Foroughi Asl, H.1
Talukdar, H.A.2
Kindt, A.S.3
-
20
-
-
77953194222
-
Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes
-
Zhong H, Beaulaurier J, Lum PY, et al. Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes. PLoS Genet. 2010;6:e1000932. doi: 10. 1371/journal. pgen. 1000932.
-
(2010)
PLoS Genet.
, vol.6
, pp. e1000932
-
-
Zhong, H.1
Beaulaurier, J.2
Lum, P.Y.3
-
21
-
-
84855267424
-
Integrating genome-wide genetic variations and monocyte expression data reveals trans-regulated gene modules in humans
-
Cardiogenics Consortium
-
Rotival M, Zeller T, Wild PS, et al; Cardiogenics Consortium. Integrating genome-wide genetic variations and monocyte expression data reveals trans-regulated gene modules in humans. PLoS Genet. 2011;7:e1002367. doi: 10. 1371/journal. pgen. 1002367.
-
(2011)
PLoS Genet.
, vol.7
, pp. e1002367
-
-
Rotival, M.1
Zeller, T.2
Wild, P.S.3
-
22
-
-
84878989857
-
Identification of CAD candidate genes in GWAS loci and their expression in vascular cells
-
Erbilgin A, Civelek M, Romanoski CE, Pan C, Hagopian R, Berliner JA, Lusis AJ. Identification of CAD candidate genes in GWAS loci and their expression in vascular cells. J Lipid Res. 2013;54:1894-1905. doi: 10. 1194/jlr. M037085.
-
(2013)
J Lipid Res.
, vol.54
, pp. 1894-1905
-
-
Erbilgin, A.1
Civelek, M.2
Romanoski, C.E.3
Pan, C.4
Hagopian, R.5
Berliner, J.A.6
Lusis, A.J.7
-
23
-
-
80052733701
-
A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease
-
Wild PS, Zeller T, Schillert A, et al. A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease. Circ Cardiovasc Genet. 2011;4:403-412. doi: 10. 1161/ CIRCGENETICS. 110. 958728.
-
(2011)
Circ Cardiovasc Genet.
, vol.4
, pp. 403-412
-
-
Wild, P.S.1
Zeller, T.2
Schillert, A.3
-
24
-
-
84860317030
-
Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles
-
Fairfax BP, Makino S, Radhakrishnan J, Plant K, Leslie S, Dilthey A, Ellis P, Langford C, Vannberg FO, Knight JC. Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles. Nat Genet. 2012;44:502-510. doi: 10. 1038/ng. 2205.
-
(2012)
Nat Genet.
, vol.44
, pp. 502-510
-
-
Fairfax, B.P.1
Makino, S.2
Radhakrishnan, J.3
Plant, K.4
Leslie, S.5
Dilthey, A.6
Ellis, P.7
Langford, C.8
Vannberg, F.O.9
Knight, J.C.10
-
25
-
-
84887099827
-
Discovery and refinement of loci associated with lipid levels
-
Global Lipids Genetics C
-
Willer CJ, Schmidt EM, et al; Global Lipids Genetics C. Discovery and refinement of loci associated with lipid levels. Nat Genet. 2013;45:1274-1283. doi: 10. 1038/ng. 2797.
-
(2013)
Nat Genet.
, vol.45
, pp. 1274-1283
-
-
Willer, C.J.1
Schmidt, E.M.2
-
26
-
-
84897379124
-
Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation
-
Miller CL, Haas U, Diaz R, Leeper NJ, Kundu RK, Patlolla B, Assimes TL, Kaiser FJ, Perisic L, Hedin U, Maegdefessel L, Schunkert H, Erdmann J, Quertermous T, Sczakiel G. Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation. PLoS Genet. 2014;10:e1004263. doi: 10. 1371/journal. pgen. 1004263.
-
(2014)
PLoS Genet.
, vol.10
, pp. e1004263
-
-
Miller, C.L.1
Haas, U.2
Diaz, R.3
Leeper, N.J.4
Kundu, R.K.5
Patlolla, B.6
Assimes, T.L.7
Kaiser, F.J.8
Perisic, L.9
Hedin, U.10
Maegdefessel, L.11
Schunkert, H.12
Erdmann, J.13
Quertermous, T.14
Sczakiel, G.15
-
27
-
-
78049420577
-
MicroSNiPer: A web tool for prediction of SNP effects on putative microRNA targets
-
Barenboim M, Zoltick BJ, Guo Y, Weinberger DR. MicroSNiPer: A web tool for prediction of SNP effects on putative microRNA targets. Hum Mutat. 2010;31:1223-1232. doi: 10. 1002/humu. 21349.
-
(2010)
Hum Mutat.
, vol.31
, pp. 1223-1232
-
-
Barenboim, M.1
Zoltick, B.J.2
Guo, Y.3
Weinberger, D.R.4
-
28
-
-
70349326007
-
Genomic interactions: Chromatin loops and gene meeting points in transcriptional regulation
-
Sexton T, Bantignies F, Cavalli G. Genomic interactions: chromatin loops and gene meeting points in transcriptional regulation. Semin Cell Dev Biol. 2009;20:849-855. doi: 10. 1016/j. semcdb. 2009. 06. 004.
-
(2009)
Semin Cell Dev Biol.
, vol.20
, pp. 849-855
-
-
Sexton, T.1
Bantignies, F.2
Cavalli, G.3
-
29
-
-
84865800494
-
The long-range interaction landscape of gene promoters
-
Sanyal A, Lajoie BR, Jain G, Dekker J. The long-range interaction landscape of gene promoters. Nature. 2012;489:109-113. doi: 10. 1038/ nature11279.
-
(2012)
Nature.
, vol.489
, pp. 109-113
-
-
Sanyal, A.1
Lajoie, B.R.2
Jain, G.3
Dekker, J.4
-
30
-
-
67651205715
-
Identifying relationships among genomic disease regions: Predicting genes at pathogenic SNP associations and rare deletions
-
International Schizophrenia Consortium
-
Raychaudhuri S, Plenge RM, Rossin EJ, Ng AC, Purcell SM, Sklar P, Scolnick EM, Xavier RJ, Altshuler D, Daly MJ; International Schizophrenia Consortium. Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions. PLoS Genet. 2009;5:e1000534. doi: 10. 1371/journal. pgen. 1000534.
-
(2009)
PLoS Genet.
, vol.5
, pp. e1000534
-
-
Raychaudhuri, S.1
Plenge, R.M.2
Rossin, E.J.3
Ng, A.C.4
Purcell, S.M.5
Sklar, P.6
Scolnick, E.M.7
Xavier, R.J.8
Altshuler, D.9
Daly, M.J.10
-
31
-
-
84923096381
-
Biological interpretation of genome-wide association studies using predicted gene functions
-
Genetic Investigation of ANthropometric Traits (GIANT) Consortium
-
Pers TH, Karjalainen JM, Chan Y, et al; Genetic Investigation of ANthropometric Traits (GIANT) Consortium. Biological interpretation of genome-wide association studies using predicted gene functions. Nat Commun. 2015;6:5890. doi: 10. 1038/ncomms6890.
-
(2015)
Nat Commun.
, vol.6
, pp. 5890
-
-
Pers, T.H.1
Karjalainen, J.M.2
Chan, Y.3
-
32
-
-
84859727275
-
The Mouse Genome Database (MGD): Comprehensive resource for genetics and genomics of the laboratory mouse
-
Database issue
-
Eppig JT, Blake JA, Bult CJ, Kadin JA, Richardson JE; Mouse Genome Database Group. The Mouse Genome Database (MGD): comprehensive resource for genetics and genomics of the laboratory mouse. Nucleic Acids Res. 2012;40(Database issue):D881-D886. doi: 10. 1093/nar/gkr974.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. D881-D886
-
-
Eppig, J.T.1
Blake, J.A.2
Bult, C.J.3
Kadin, J.A.4
Richardson, J.E.5
-
33
-
-
66349110163
-
Annotating the human genome with Disease Ontology
-
Osborne JD, Flatow J, Holko M, Lin SM, Kibbe WA, Zhu LJ, Danila MI, Feng G, Chisholm RL. Annotating the human genome with Disease Ontology. BMC Genomics. 2009;10(suppl 1):S6. doi: 10. 1186/1471-2164-10-S1-S6.
-
(2009)
BMC Genomics.
, vol.10
, pp. S6
-
-
Osborne, J.D.1
Flatow, J.2
Holko, M.3
Lin, S.M.4
Kibbe, W.A.5
Zhu, L.J.6
Danila, M.I.7
Feng, G.8
Chisholm, R.L.9
-
34
-
-
84876008750
-
The ConsensusPathDB interaction database: 2013 update
-
Database issue
-
Kamburov A, Stelzl U, Lehrach H, Herwig R. The ConsensusPathDB interaction database: 2013 update. Nucleic Acids Res. 2013;41(Database issue):D793-D800. doi: 10. 1093/nar/gks1055.
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. D793-D800
-
-
Kamburov, A.1
Stelzl, U.2
Lehrach, H.3
Herwig, R.4
-
35
-
-
0034069495
-
Gene ontology: Tool for the unification of biology. The Gene Ontology Consortium
-
Ashburner M, Ball CA, Blake JA, et al. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet. 2000;25:25-29 doi: 10. 1038/75556.
-
(2000)
Nat Genet.
, vol.25
, pp. 25-29
-
-
Ashburner, M.1
Ball, C.A.2
Blake, J.A.3
-
36
-
-
84946735654
-
Gene ontology consortium: Going forward
-
Gene Ontology C. Gene ontology consortium: Going forward. Nucleic acids research. 2015;43:D1049-D1056.
-
(2015)
Nucleic Acids Research.
, vol.43
, pp. D1049-D1056
-
-
Gene Ontology, C.1
-
37
-
-
84867332713
-
Hybrid mouse diversity panel: A panel of inbred mouse strains suitable for analysis of complex genetic traits
-
Ghazalpour A, Rau CD, Farber CR, et al. Hybrid mouse diversity panel: A panel of inbred mouse strains suitable for analysis of complex genetic traits. Mamm Genome. 2012;23:680-692. doi: 10. 1007/s00335-012-9411-5.
-
(2012)
Mamm Genome.
, vol.23
, pp. 680-692
-
-
Ghazalpour, A.1
Rau, C.D.2
Farber, C.R.3
-
38
-
-
25844523898
-
Downregulated REST transcription factor is a switch enabling critical potassium channel expression and cell proliferation
-
Cheong A, Bingham AJ, Li J, Kumar B, Sukumar P, Munsch C, Buckley NJ, Neylon CB, Porter KE, Beech DJ, Wood IC. Downregulated REST transcription factor is a switch enabling critical potassium channel expression and cell proliferation. Mol Cell. 2005;20:45-52. doi: 10. 1016/j. molcel. 2005. 08. 030.
-
(2005)
Mol Cell.
, vol.20
, pp. 45-52
-
-
Cheong, A.1
Bingham, A.J.2
Li, J.3
Kumar, B.4
Sukumar, P.5
Munsch, C.6
Buckley, N.J.7
Neylon, C.B.8
Porter, K.E.9
Beech, D.J.10
Wood, I.C.11
-
39
-
-
0029594509
-
Glucagon-like peptide-1 and control of insulin secretion
-
Thorens B. Glucagon-like peptide-1 and control of insulin secretion. Diabete Metab. 1995;21:311-318.
-
(1995)
Diabete Metab.
, vol.21
, pp. 311-318
-
-
Thorens, B.1
-
40
-
-
0036068322
-
Inhibition of gastric inhibitory polypeptide signaling prevents obesity
-
Miyawaki K, Yamada Y, Ban N, et al. Inhibition of gastric inhibitory polypeptide signaling prevents obesity. Nat Med. 2002;8:738-742. doi: 10. 1038/nm727.
-
(2002)
Nat Med.
, vol.8
, pp. 738-742
-
-
Miyawaki, K.1
Yamada, Y.2
Ban, N.3
-
41
-
-
84903207650
-
Chronic reduction of GIP secretion alleviates obesity and insulin resistance under high-fat diet conditions
-
Nasteska D, Harada N, Suzuki K, Yamane S, Hamasaki A, Joo E, Iwasaki K, Shibue K, Harada T, Inagaki N. Chronic reduction of GIP secretion alleviates obesity and insulin resistance under high-fat diet conditions. Diabetes. 2014;63:2332-2343. doi: 10. 2337/db13-1563.
-
(2014)
Diabetes.
, vol.63
, pp. 2332-2343
-
-
Nasteska, D.1
Harada, N.2
Suzuki, K.3
Yamane, S.4
Hamasaki, A.5
Joo, E.6
Iwasaki, K.7
Shibue, K.8
Harada, T.9
Inagaki, N.10
-
42
-
-
0034724504
-
Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro
-
Nagase T, Kikuno R, Ishikawa K, Hirosawa M, Ohara O. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 2000;7:143-150.
-
(2000)
DNA Res.
, vol.7
, pp. 143-150
-
-
Nagase, T.1
Kikuno, R.2
Ishikawa, K.3
Hirosawa, M.4
Ohara, O.5
-
43
-
-
84861184197
-
Developmental expression and cardiac transcriptional regulation of Myh7b, a third myosin heavy chain in the vertebrate heart
-
Warkman AS, Whitman SA, Miller MK, Garriock RJ, Schwach CM, Gregorio CC, Krieg PA. Developmental expression and cardiac transcriptional regulation of Myh7b, a third myosin heavy chain in the vertebrate heart. Cytoskeleton (Hoboken). 2012;69:324-335. doi: 10. 1002/cm. 21029.
-
(2012)
Cytoskeleton (Hoboken).
, vol.69
, pp. 324-335
-
-
Warkman, A.S.1
Whitman, S.A.2
Miller, M.K.3
Garriock, R.J.4
Schwach, C.M.5
Gregorio, C.C.6
Krieg, P.A.7
-
44
-
-
84890557979
-
Dysfunctional nitric oxide signalling increases risk of myocardial infarction
-
CARDIoGRAM
-
Erdmann J, Stark K, Esslinger UB, et al; CARDIoGRAM. Dysfunctional nitric oxide signalling increases risk of myocardial infarction. Nature. 2013;504:432-436. doi: 10. 1038/nature12722.
-
(2013)
Nature.
, vol.504
, pp. 432-436
-
-
Erdmann, J.1
Stark, K.2
Esslinger, U.B.3
-
45
-
-
84880779995
-
Disease-related growth factor and embryonic signaling pathways modulate an enhancer of TCF21 expression at the 6q23. 2 coronary heart disease locus
-
Miller CL, Anderson DR, Kundu RK, Raiesdana A, Nürnberg ST, Diaz R, Cheng K, Leeper NJ, Chen CH, Chang IS, Schadt EE, Hsiung CA, Assimes TL, Quertermous T. Disease-related growth factor and embryonic signaling pathways modulate an enhancer of TCF21 expression at the 6q23. 2 coronary heart disease locus. PLoS Genet. 2013;9:e1003652. doi: 10. 1371/journal. pgen. 1003652.
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003652
-
-
Miller, C.L.1
Anderson, D.R.2
Kundu, R.K.3
Raiesdana, A.4
Nürnberg, S.T.5
Diaz, R.6
Cheng, K.7
Leeper, N.J.8
Chen, C.H.9
Chang, I.S.10
Schadt, E.E.11
Hsiung, C.A.12
Assimes, T.L.13
Quertermous, T.14
-
46
-
-
84856136800
-
Recent studies of the human chromosome 9p21 locus, which is associated with atherosclerosis in human populations
-
Holdt LM, Teupser D. Recent studies of the human chromosome 9p21 locus, which is associated with atherosclerosis in human populations. Arterioscler Thromb Vasc Biol. 2012;32:196-206. doi: 10. 1161/ ATVBAHA. 111. 232678.
-
(2012)
Arterioscler Thromb Vasc Biol.
, vol.32
, pp. 196-206
-
-
Holdt, L.M.1
Teupser, D.2
-
47
-
-
84925089678
-
The role of regulatory variation in complex traits and disease
-
Albert FW, Kruglyak L. The role of regulatory variation in complex traits and disease. Nat Rev Genet. 2015;16:197-212. doi: 10. 1038/nrg3891.
-
(2015)
Nat Rev Genet.
, vol.16
, pp. 197-212
-
-
Albert, F.W.1
Kruglyak, L.2
-
48
-
-
84897855294
-
Obesity-associated variants within FTO form long-range functional connections with IRX3
-
Smemo S, Tena JJ, Kim KH, et al. Obesity-associated variants within FTO form long-range functional connections with IRX3. Nature. 2014;507:371-375. doi: 10. 1038/nature13138.
-
(2014)
Nature.
, vol.507
, pp. 371-375
-
-
Smemo, S.1
Tena, J.J.2
Kim, K.H.3
-
49
-
-
84897379124
-
Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation
-
Miller CL, Haas U, Diaz R, Leeper NJ, Kundu RK, Patlolla B, Assimes TL, Kaiser FJ, Perisic L, Hedin U, Maegdefessel L, Schunkert H, Erdmann J, Quertermous T, Sczakiel G. Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation. PLoS Genet. 2014;10:e1004263. doi: 10. 1371/journal. pgen. 1004263.
-
(2014)
PLoS Genet.
, vol.10
, pp. e1004263
-
-
Miller, C.L.1
Haas, U.2
Diaz, R.3
Leeper, N.J.4
Kundu, R.K.5
Patlolla, B.6
Assimes, T.L.7
Kaiser, F.J.8
Perisic, L.9
Hedin, U.10
Maegdefessel, L.11
Schunkert, H.12
Erdmann, J.13
Quertermous, T.14
Sczakiel, G.15
-
50
-
-
79952256739
-
The architecture of gene regulatory variation across multiple human tissues: The MuTHER study
-
Nica AC, Parts L, Glass D, et al; MuTHER Consortium. The architecture of gene regulatory variation across multiple human tissues: the MuTHER study. PLoS Genet. 2011;7:e1002003. doi: 10. 1371/journal. pgen. 1002003.
-
(2011)
PLoS Genet.
, vol.7
, pp. e1002003
-
-
Nica, A.C.1
Parts, L.2
Glass, D.3
-
51
-
-
84884611024
-
Integrative modeling of eQTLs and cis-regulatory elements suggests mechanisms underlying cell type specificity of eQTLs
-
Brown CD, Mangravite LM, Engelhardt BE. Integrative modeling of eQTLs and cis-regulatory elements suggests mechanisms underlying cell type specificity of eQTLs. PLoS Genet. 2013;9:e1003649. doi: 10. 1371/ journal. pgen. 1003649.
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003649
-
-
Brown, C.D.1
Mangravite, L.M.2
Engelhardt, B.E.3
-
52
-
-
84857487802
-
Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression
-
Fu J, Wolfs MG, Deelen P, et al. Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression. PLoS Genet. 2012;8:e1002431. doi: 10. 1371/journal. pgen. 1002431.
-
(2012)
PLoS Genet.
, vol.8
, pp. e1002431
-
-
Fu, J.1
Wolfs, M.G.2
Deelen, P.3
-
53
-
-
84890231680
-
Beyond GWASs: Illuminating the dark road from association to function
-
Edwards SL, Beesley J, French JD, Dunning AM. Beyond GWASs: illuminating the dark road from association to function. Am J Hum Genet. 2013;93:779-797. doi: 10. 1016/j. Ajhg. 2013. 10. 012.
-
(2013)
Am J Hum Genet.
, vol.93
, pp. 779-797
-
-
Edwards, S.L.1
Beesley, J.2
French, J.D.3
Dunning, A.M.4
-
54
-
-
0038483826
-
Emergence of scaling in random networks
-
Barabasi AL, Albert R. Emergence of scaling in random networks. Science. 1999;286:509-512.
-
(1999)
Science.
, vol.286
, pp. 509-512
-
-
Barabasi, A.L.1
Albert, R.2
-
55
-
-
84931572130
-
Towards a molecular understanding of microRNAmediated gene silencing
-
Jonas S, Izaurralde E. Towards a molecular understanding of microRNAmediated gene silencing. Nat Rev Genet. 2015;16:421-433. doi: 10. 1038/ nrg3965.
-
(2015)
Nat Rev Genet.
, vol.16
, pp. 421-433
-
-
Jonas, S.1
Izaurralde, E.2
-
56
-
-
84901004299
-
The rise of regulatory RNA
-
Morris KV, Mattick JS. The rise of regulatory RNA. Nat Rev Genet. 2014;15:423-437. doi: 10. 1038/nrg3722.
-
(2014)
Nat Rev Genet.
, vol.15
, pp. 423-437
-
-
Morris, K.V.1
Mattick, J.S.2
-
57
-
-
34248524473
-
Mapping networks of physical interactions between genomic elements using 5C technology
-
Dostie J, Dekker J. Mapping networks of physical interactions between genomic elements using 5C technology. Nat Protoc. 2007;2:988-1002. doi: 10. 1038/nprot. 2007. 116.
-
(2007)
Nat Protoc.
, vol.2
, pp. 988-1002
-
-
Dostie, J.1
Dekker, J.2
-
58
-
-
84938276507
-
A method to predict the impact of regulatory variants from DNA sequence
-
Lee D, Gorkin DU, Baker M, Strober BJ, Asoni AL, McCallion AS, Beer MA. A method to predict the impact of regulatory variants from DNA sequence. Nat Genet. 2015;47:955-961. doi: 10. 1038/ng. 3331.
-
(2015)
Nat Genet.
, vol.47
, pp. 955-961
-
-
Lee, D.1
Gorkin, D.U.2
Baker, M.3
Strober, B.J.4
Asoni, A.L.5
McCallion, A.S.6
Beer, M.A.7
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