Monocyte-derived dendritic cells upregulate extracellular catabolism of aggregated low-density lipoprotein on maturation, leading to foam cell formation

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 35, Issue 10, 2015, Pages 2092-2103

  Haka, Abigail S ^a   Singh, Rajesh K ^a   Grosheva, Inna ^a   Hoffner, Haley ^a   Capetillo Zarate, Estibaliz ^a   Chin, Harvey F ^a   Anandasabapathy, Niroshana ^b   Maxfield, Frederick R ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Atherosclerosis; Dendritic cells; Foam cells; Lipoproteins, LDL; Phagocytosis

Indexed keywords

AGGREGATED LOW DENSITY LIPOPROTEIN; CHOLESTEROL; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; LIPID; LOW DENSITY LIPOPROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROTIC PLAQUE; AUTOPHAGY; BONE MARROW DERIVED DENDRITIC CELL; CATABOLISM; CELL MATURATION; CELL PHAGOCYTOSIS; CONTROLLED STUDY; DENDRITIC CELL; EXOPHAGY; EXPERIMENTAL ATHEROSCLEROSIS; EXTRACELLULAR SPACE; FOAM CELL; HUMAN; HUMAN CELL; INTERNALIZATION; LIPID STORAGE; MONOCYTE; MONOCYTE DERIVED DENDRITIC CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; UPREGULATION; ANIMAL; ATHEROSCLEROSIS; CELL CULTURE; COMPARATIVE STUDY; CYTOLOGY; DISEASE MODEL; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PHAGOCYTOSIS; PHYSIOLOGY; RANDOMIZATION; TRANSCRIPTION INITIATION;

ANIMALS; ATHEROSCLEROSIS; CELLS, CULTURED; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; FOAM CELLS; HUMANS; LIPOPROTEINS, LDL; MICE; MICE, KNOCKOUT; MONOCYTES; PHAGOCYTOSIS; RANDOM ALLOCATION; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION;

EID: 84942241918     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.115.305843     Document Type: Article

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