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Volumn 96, Issue 1, 2015, Pages 9-19

Cancer stem cells in oesophageal squamous cell carcinoma: Identification, prognostic and treatment perspectives

Author keywords

Cancer stem cell; CSC biology; CSC markers; Oesophageal squamous cell carcinoma

Indexed keywords

ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE ISOENZYME 1; ANTINEOPLASTIC AGENT; BREAST CANCER RESISTANCE PROTEIN; CD133 ANTIGEN; CD271 ANTIGEN; CELL MARKER; HERMES ANTIGEN; LYMPHOCYTE ANTIGEN; NUCLEIC ACID BINDING PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; PODOPLANIN; PROTEIN HIWI; SAL LIKE PROTEIN 4; THY 1 ANTIGEN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; ISOENZYME; POU5F1 PROTEIN, HUMAN; PROM1 PROTEIN, HUMAN; RETINAL DEHYDROGENASE; SOX2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR SOX;

EID: 84942192030     PISSN: 10408428     EISSN: 18790461     Source Type: Journal    
DOI: 10.1016/j.critrevonc.2015.04.007     Document Type: Review
Times cited : (70)

References (125)
  • 1
    • 33646568784 scopus 로고    scopus 로고
    • Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world
    • Kamangar F., Dores G.M., Anderson W.F. Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. J Clin Oncol 2006, 24:2137-2150.
    • (2006) J Clin Oncol , vol.24 , pp. 2137-2150
    • Kamangar, F.1    Dores, G.M.2    Anderson, W.F.3
  • 2
    • 0035166704 scopus 로고    scopus 로고
    • Esophageal basaloid squamous cell carcinoma: an unique clinicopathological entity with telomerase activity as a prognostic indicator
    • Lam K.Y., Law S., Tung P.H., Wong J. Esophageal basaloid squamous cell carcinoma: an unique clinicopathological entity with telomerase activity as a prognostic indicator. J Pathol 2001, 195:435-442.
    • (2001) J Pathol , vol.195 , pp. 435-442
    • Lam, K.Y.1    Law, S.2    Tung, P.H.3    Wong, J.4
  • 4
    • 0028330766 scopus 로고
    • Squamous cell carcinoma of the esophagus with mucin-secreting component (mucoepidermoid carcinoma and adenosquamous cell carcinoma): a clinicopathologic study and a review of literature
    • Lam K.Y., Dickens P., Loke S.L., Fok M., Ma L., Wong J. Squamous cell carcinoma of the esophagus with mucin-secreting component (mucoepidermoid carcinoma and adenosquamous cell carcinoma): a clinicopathologic study and a review of literature. Eur J Surg Oncol 1994, 20:25-31.
    • (1994) Eur J Surg Oncol , vol.20 , pp. 25-31
    • Lam, K.Y.1    Dickens, P.2    Loke, S.L.3    Fok, M.4    Ma, L.5    Wong, J.6
  • 6
    • 0031152158 scopus 로고    scopus 로고
    • Pathology of esophageal cancers: local experience and current insights
    • Lam K.Y., Ma L. Pathology of esophageal cancers: local experience and current insights. Chin Med J 1997, 110:459-464.
    • (1997) Chin Med J , vol.110 , pp. 459-464
    • Lam, K.Y.1    Ma, L.2
  • 7
    • 0033963695 scopus 로고    scopus 로고
    • Critical review: molecular biology of esophageal squamous cell carcinoma
    • Lam A.K.Y. Critical review: molecular biology of esophageal squamous cell carcinoma. Crit Rev Oncol Hematol 2000, 33:71-90.
    • (2000) Crit Rev Oncol Hematol , vol.33 , pp. 71-90
    • Lam, A.K.Y.1
  • 8
    • 0034789420 scopus 로고    scopus 로고
    • Telomerase activity in small cell esophageal carcinoma
    • Chow V., Law S., Lam K.Y., Luk J.M., Wong J. Telomerase activity in small cell esophageal carcinoma. Dis Esophagus 2001, 14:139-142.
    • (2001) Dis Esophagus , vol.14 , pp. 139-142
    • Chow, V.1    Law, S.2    Lam, K.Y.3    Luk, J.M.4    Wong, J.5
  • 9
    • 0033950599 scopus 로고    scopus 로고
    • Esophageal small cell carcinoma: clinicopathologic parameters, p53 overexpression, proliferative marker, and their impact on pathogenesis
    • Lam K.Y., Law S., Tung P.H., Wong J. Esophageal small cell carcinoma: clinicopathologic parameters, p53 overexpression, proliferative marker, and their impact on pathogenesis. Arch Pathol Lab Med 2000, 124:228-233.
    • (2000) Arch Pathol Lab Med , vol.124 , pp. 228-233
    • Lam, K.Y.1    Law, S.2    Tung, P.H.3    Wong, J.4
  • 10
    • 0030997699 scopus 로고    scopus 로고
    • Prevalence and predictive value of p53 mutation in patients with esophageal squamous cell carcinomas: a prospective clinicopatholgical study and survival analysis of 70 patients
    • Lam K.Y., Tsao S.W., Zhang D., Law S., He D., Ma L., et al. Prevalence and predictive value of p53 mutation in patients with esophageal squamous cell carcinomas: a prospective clinicopatholgical study and survival analysis of 70 patients. Int J Cancer 1997, 74:212-219.
    • (1997) Int J Cancer , vol.74 , pp. 212-219
    • Lam, K.Y.1    Tsao, S.W.2    Zhang, D.3    Law, S.4    He, D.5    Ma, L.6
  • 11
    • 84877808476 scopus 로고    scopus 로고
    • Oncogene GAEC1 regulates CAPN10 expression which predicts survival in esophageal squamous cell carcinoma
    • Chan D., Tsoi M.Y., Liu C.D., Chan S.H., Law S.Y., Chan K.W., et al. Oncogene GAEC1 regulates CAPN10 expression which predicts survival in esophageal squamous cell carcinoma. World J Gastroenterol 2013, 19:2772-2780.
    • (2013) World J Gastroenterol , vol.19 , pp. 2772-2780
    • Chan, D.1    Tsoi, M.Y.2    Liu, C.D.3    Chan, S.H.4    Law, S.Y.5    Chan, K.W.6
  • 12
    • 0033180047 scopus 로고    scopus 로고
    • The clinicopathological significance of p21 and p53 expression in esophageal squamous cell carcinoma: an analysis of 153 patients
    • Lam K.Y., Law S., Lo T., Tung H.M., Wong J. The clinicopathological significance of p21 and p53 expression in esophageal squamous cell carcinoma: an analysis of 153 patients. Am J Gastroenterol 1999, 94:2060-2068.
    • (1999) Am J Gastroenterol , vol.94 , pp. 2060-2068
    • Lam, K.Y.1    Law, S.2    Lo, T.3    Tung, H.M.4    Wong, J.5
  • 13
    • 13344281014 scopus 로고    scopus 로고
    • Prognostic implication of proliferative markers MIB-1 and PC 10 in esophageal squamous cell carcinoma
    • Lam K.Y., Law S.Y.K., So M.K.P., Fok M., Ma L.T., Wong J. Prognostic implication of proliferative markers MIB-1 and PC 10 in esophageal squamous cell carcinoma. Cancer 1996, 77:7-13.
    • (1996) Cancer , vol.77 , pp. 7-13
    • Lam, K.Y.1    Law, S.Y.K.2    So, M.K.P.3    Fok, M.4    Ma, L.T.5    Wong, J.6
  • 14
    • 77955012425 scopus 로고    scopus 로고
    • Histological regression of squamous esophageal carcinoma assessed by percentage of residual viable cells after neoadjuvant chemoradiation is an important prognostic factor
    • Tong D.K., Law S., Kwong D.L., Chan K.W., Lam A.K., Wong K.H. Histological regression of squamous esophageal carcinoma assessed by percentage of residual viable cells after neoadjuvant chemoradiation is an important prognostic factor. Ann Surg Oncol 2010, 17:2184-2192.
    • (2010) Ann Surg Oncol , vol.17 , pp. 2184-2192
    • Tong, D.K.1    Law, S.2    Kwong, D.L.3    Chan, K.W.4    Lam, A.K.5    Wong, K.H.6
  • 15
    • 0030738995 scopus 로고    scopus 로고
    • Pre-operative chemotherapy for squamous cell carcinoma of the esophagus: do histological assessment and p53 overexpression predict chemo-responsiveness
    • Lam K.Y., Law S., Ma L.T., Ong S.K., Wong J. Pre-operative chemotherapy for squamous cell carcinoma of the esophagus: do histological assessment and p53 overexpression predict chemo-responsiveness. Eur J Cancer 1997, 33:1221-1225.
    • (1997) Eur J Cancer , vol.33 , pp. 1221-1225
    • Lam, K.Y.1    Law, S.2    Ma, L.T.3    Ong, S.K.4    Wong, J.5
  • 17
    • 84907742261 scopus 로고    scopus 로고
    • Lymph node enlargement after definitive chemoradiotherapy for clinical stage I esophageal squamous cell carcinoma
    • Hayashi Y., Nishida T., Tsujii M., Tsutsui S., Yamamoto K., Isohashi F., et al. Lymph node enlargement after definitive chemoradiotherapy for clinical stage I esophageal squamous cell carcinoma. BMC Cancer 2014, 14:706.
    • (2014) BMC Cancer , vol.14 , pp. 706
    • Hayashi, Y.1    Nishida, T.2    Tsujii, M.3    Tsutsui, S.4    Yamamoto, K.5    Isohashi, F.6
  • 18
    • 0026681035 scopus 로고
    • Low dose preoperative radiotherapy for carcinoma of the oesophagus: results of a randomized clinical trial
    • Arnott S.J., Duncan W., Kerr G.R., Walbaum P.R., Cameron E., Jack W.J., et al. Low dose preoperative radiotherapy for carcinoma of the oesophagus: results of a randomized clinical trial. Radiother Oncol 1992, 24:108-113.
    • (1992) Radiother Oncol , vol.24 , pp. 108-113
    • Arnott, S.J.1    Duncan, W.2    Kerr, G.R.3    Walbaum, P.R.4    Cameron, E.5    Jack, W.J.6
  • 19
    • 0027055350 scopus 로고
    • Pre-operative radiotherapy prolongs survival in operable esophageal carcinoma: a randomized, multicentre study of pre-operative radiotherapy and chemotherapy. The second Scandinavian trial in esophageal cancer
    • Nygaard K., Hagen S., Hansen H.S., Hatlevoll R., Hultborn R., Jakobsen A., et al. Pre-operative radiotherapy prolongs survival in operable esophageal carcinoma: a randomized, multicentre study of pre-operative radiotherapy and chemotherapy. The second Scandinavian trial in esophageal cancer. World J Surg 1992, 16:1104-1110.
    • (1992) World J Surg , vol.16 , pp. 1104-1110
    • Nygaard, K.1    Hagen, S.2    Hansen, H.S.3    Hatlevoll, R.4    Hultborn, R.5    Jakobsen, A.6
  • 20
    • 84906254637 scopus 로고    scopus 로고
    • Re-evaluating the optimal radiation dose for definitive chemoradiotherapy for esophageal squamous cell carcinoma
    • He L., Allen P.K., Potter A., Wang J., Chang J.Y., Gomez D.R., et al. Re-evaluating the optimal radiation dose for definitive chemoradiotherapy for esophageal squamous cell carcinoma. J Thorac Oncol 2014, 9:1398-1405.
    • (2014) J Thorac Oncol , vol.9 , pp. 1398-1405
    • He, L.1    Allen, P.K.2    Potter, A.3    Wang, J.4    Chang, J.Y.5    Gomez, D.R.6
  • 21
    • 69249147027 scopus 로고    scopus 로고
    • Effects of neoadjuvant radiochemotherapy on pathological staging and prognosis for locally advanced esophageal squamous cell carcinoma
    • Cao X.F., He X.T., Ji L., Xiao J., Lv J. Effects of neoadjuvant radiochemotherapy on pathological staging and prognosis for locally advanced esophageal squamous cell carcinoma. Dis Esophagus 2009, 22:477-481.
    • (2009) Dis Esophagus , vol.22 , pp. 477-481
    • Cao, X.F.1    He, X.T.2    Ji, L.3    Xiao, J.4    Lv, J.5
  • 22
    • 84863203881 scopus 로고    scopus 로고
    • Photodynamic therapy as salvage treatment for local failure after chemoradiotherapy in patients with esophageal squamous cell carcinoma: a phase II study
    • Yano T., Muto M., Minashi K., Iwasaki J., Kojima T., Fuse N., et al. Photodynamic therapy as salvage treatment for local failure after chemoradiotherapy in patients with esophageal squamous cell carcinoma: a phase II study. Int J Cancer 2012, 131:1228-1234.
    • (2012) Int J Cancer , vol.131 , pp. 1228-1234
    • Yano, T.1    Muto, M.2    Minashi, K.3    Iwasaki, J.4    Kojima, T.5    Fuse, N.6
  • 24
    • 84885508334 scopus 로고    scopus 로고
    • Three-dimensional conformal radiotherapy with concurrent chemotherapy for postoperative recurrence of esophageal squamous cell carcinoma: clinical efficacy and failure pattern
    • Bao Y., Liu S., Zhou Q., Cai P., Anfossi S., Li Q., et al. Three-dimensional conformal radiotherapy with concurrent chemotherapy for postoperative recurrence of esophageal squamous cell carcinoma: clinical efficacy and failure pattern. Radiat Oncol 2013, 8:241.
    • (2013) Radiat Oncol , vol.8 , pp. 241
    • Bao, Y.1    Liu, S.2    Zhou, Q.3    Cai, P.4    Anfossi, S.5    Li, Q.6
  • 25
    • 79961127318 scopus 로고    scopus 로고
    • Long-term results of salvage photodynamic therapy for patients with local failure after chemoradiotherapy for esophageal squamous cell carcinoma
    • Yano T., Muto M., Minashi K., Onozawa M., Nihei K., Ishikura S., et al. Long-term results of salvage photodynamic therapy for patients with local failure after chemoradiotherapy for esophageal squamous cell carcinoma. Endoscopy 2011, 43:657-663.
    • (2011) Endoscopy , vol.43 , pp. 657-663
    • Yano, T.1    Muto, M.2    Minashi, K.3    Onozawa, M.4    Nihei, K.5    Ishikura, S.6
  • 26
    • 50649114915 scopus 로고    scopus 로고
    • Nonoperable patients with superficial esophageal cancer treated by photodynamic therapy after chemoradiotherapy have more severe complications than patients treated in primary intent
    • Lecleire S., Di Fiore F., Antonietti M., Ben-Soussan E., Hochain P., Lerebours E., et al. Nonoperable patients with superficial esophageal cancer treated by photodynamic therapy after chemoradiotherapy have more severe complications than patients treated in primary intent. Am J Gastroenterol 2008, 103:2215-2219.
    • (2008) Am J Gastroenterol , vol.103 , pp. 2215-2219
    • Lecleire, S.1    Di Fiore, F.2    Antonietti, M.3    Ben-Soussan, E.4    Hochain, P.5    Lerebours, E.6
  • 27
    • 84856501335 scopus 로고    scopus 로고
    • The developing cancer stem-cell model: clinical challenges and opportunities
    • Vermeulen L., de Sousa e Melo F., Richel D.J., Medema J.P. The developing cancer stem-cell model: clinical challenges and opportunities. Lancet Oncol 2012, 13:e83-e89.
    • (2012) Lancet Oncol , vol.13 , pp. e83-e89
    • Vermeulen, L.1    de Sousa e Melo, F.2    Richel, D.J.3    Medema, J.P.4
  • 28
    • 84916244865 scopus 로고    scopus 로고
    • Epigenetic regulation of CD271, a potential cancer stem cell marker associated with chemoresistance and metastatic capacity
    • Li S., Yue D., Chen X., Wang L., Li J., Ping Y., et al. Epigenetic regulation of CD271, a potential cancer stem cell marker associated with chemoresistance and metastatic capacity. Oncol Rep 2015, 33:425-432.
    • (2015) Oncol Rep , vol.33 , pp. 425-432
    • Li, S.1    Yue, D.2    Chen, X.3    Wang, L.4    Li, J.5    Ping, Y.6
  • 29
    • 84864288026 scopus 로고    scopus 로고
    • HAX-1 promotes the chemoresistance, invasion, and tumorigenicity of esophageal squamous carcinoma cells
    • Sun S.J., Feng L., Zhao G.Q., Dong Z.M. HAX-1 promotes the chemoresistance, invasion, and tumorigenicity of esophageal squamous carcinoma cells. Dig Dis Sci 2012, 57:1838-1846.
    • (2012) Dig Dis Sci , vol.57 , pp. 1838-1846
    • Sun, S.J.1    Feng, L.2    Zhao, G.Q.3    Dong, Z.M.4
  • 31
    • 59249091316 scopus 로고    scopus 로고
    • Targeting beta1 integrin restores sensitivity to docetaxel of esophageal squamous cell carcinoma
    • Mori R., Ishiguro H., Kuwabara Y., Kimura M., Mitsui A., Tomoda K., et al. Targeting beta1 integrin restores sensitivity to docetaxel of esophageal squamous cell carcinoma. Oncol Rep 2008, 20:1345-1351.
    • (2008) Oncol Rep , vol.20 , pp. 1345-1351
    • Mori, R.1    Ishiguro, H.2    Kuwabara, Y.3    Kimura, M.4    Mitsui, A.5    Tomoda, K.6
  • 32
    • 84865367715 scopus 로고    scopus 로고
    • Bmi-1 confers adaptive radioresistance to KYSE-150R esophageal carcinoma cells
    • Wang G., Liu L., Sharma S., Liu H., Yang W., Sun X., et al. Bmi-1 confers adaptive radioresistance to KYSE-150R esophageal carcinoma cells. Biochem Biophys Res Commun 2012, 425:309-314.
    • (2012) Biochem Biophys Res Commun , vol.425 , pp. 309-314
    • Wang, G.1    Liu, L.2    Sharma, S.3    Liu, H.4    Yang, W.5    Sun, X.6
  • 33
    • 84877666481 scopus 로고    scopus 로고
    • CD44 integrates signaling in normal stem cell, cancer stem cell and (pre)metastatic niches
    • Williams K., Motiani K., Giridhar P.V., Kasper S. CD44 integrates signaling in normal stem cell, cancer stem cell and (pre)metastatic niches. Exp Biol Med (Maywood) 2013, 238:324-338.
    • (2013) Exp Biol Med (Maywood) , vol.238 , pp. 324-338
    • Williams, K.1    Motiani, K.2    Giridhar, P.V.3    Kasper, S.4
  • 35
    • 84873597497 scopus 로고    scopus 로고
    • Notch1 is a 5-fluorouracil resistant and poor survival marker in human esophagus squamous cell carcinomas
    • Liu J., Fan H., Ma Y., Liang D., Huang R., Wang J., et al. Notch1 is a 5-fluorouracil resistant and poor survival marker in human esophagus squamous cell carcinomas. PLoS One 2013, 8:e56141.
    • (2013) PLoS One , vol.8 , pp. e56141
    • Liu, J.1    Fan, H.2    Ma, Y.3    Liang, D.4    Huang, R.5    Wang, J.6
  • 36
    • 84875582123 scopus 로고    scopus 로고
    • PITX2: a promising predictive biomarker of patients' prognosis and chemoradioresistance in esophageal squamous cell carcinoma
    • Zhang J.X., Tong Z.T., Yang L., Wang F., Chai H.P., Zhang F., et al. PITX2: a promising predictive biomarker of patients' prognosis and chemoradioresistance in esophageal squamous cell carcinoma. Int J Cancer 2013, 132:2567-2577.
    • (2013) Int J Cancer , vol.132 , pp. 2567-2577
    • Zhang, J.X.1    Tong, Z.T.2    Yang, L.3    Wang, F.4    Chai, H.P.5    Zhang, F.6
  • 37
    • 79952387584 scopus 로고    scopus 로고
    • Correlation of hedgehog signal activation with chemoradiotherapy sensitivity and survival in esophageal squamous cell carcinomas
    • Zhu W., You Z., Li T., Yu C., Tao G., Hu M., et al. Correlation of hedgehog signal activation with chemoradiotherapy sensitivity and survival in esophageal squamous cell carcinomas. Jpn J Clin Oncol 2011, 41:386-393.
    • (2011) Jpn J Clin Oncol , vol.41 , pp. 386-393
    • Zhu, W.1    You, Z.2    Li, T.3    Yu, C.4    Tao, G.5    Hu, M.6
  • 38
    • 84896709638 scopus 로고    scopus 로고
    • Biomarkers for predicting the response of esophageal squamous cell carcinoma to neoadjuvant chemoradiation therapy
    • Okumura H., Uchikado Y., Setoyama T., Matsumoto M., Owaki T., Ishigami S., et al. Biomarkers for predicting the response of esophageal squamous cell carcinoma to neoadjuvant chemoradiation therapy. Surg Today 2014, 44:421-428.
    • (2014) Surg Today , vol.44 , pp. 421-428
    • Okumura, H.1    Uchikado, Y.2    Setoyama, T.3    Matsumoto, M.4    Owaki, T.5    Ishigami, S.6
  • 40
    • 77953809918 scopus 로고    scopus 로고
    • Normal stem cells and cancer stem cells: similar and different
    • Shackleton M. Normal stem cells and cancer stem cells: similar and different. Semin Cancer Biol 2010, 20:85-92.
    • (2010) Semin Cancer Biol , vol.20 , pp. 85-92
    • Shackleton, M.1
  • 41
    • 33847296106 scopus 로고    scopus 로고
    • Targeted therapy for cancer stem cells: the patched pathway and ABC transporters
    • Lou H., Dean M. Targeted therapy for cancer stem cells: the patched pathway and ABC transporters. Oncogene 2007, 26:1357-1360.
    • (2007) Oncogene , vol.26 , pp. 1357-1360
    • Lou, H.1    Dean, M.2
  • 42
  • 43
    • 81755172443 scopus 로고    scopus 로고
    • CD133 protein N-glycosylation processing contributes to cell surface recognition of the primitive cell marker AC133 epitope
    • Mak A.B., Blakely K.M., Williams R.A., Penttilä P.A., Shukalyuk A.I., Osman K.T., et al. CD133 protein N-glycosylation processing contributes to cell surface recognition of the primitive cell marker AC133 epitope. J Biol Chem 2011, 286:41046-41056.
    • (2011) J Biol Chem , vol.286 , pp. 41046-41056
    • Mak, A.B.1    Blakely, K.M.2    Williams, R.A.3    Penttilä, P.A.4    Shukalyuk, A.I.5    Osman, K.T.6
  • 44
    • 80054003177 scopus 로고    scopus 로고
    • Targeting tumor-initiating cancer cells with dCD133KDEL shows impressive tumor reductions in a xenotransplant model of human head and neck cancer
    • Waldron N.N., Kaufman D.S., Oh S., Inde Z., Hexum M.K., Ohlfest J.R., et al. Targeting tumor-initiating cancer cells with dCD133KDEL shows impressive tumor reductions in a xenotransplant model of human head and neck cancer. Mol Cancer Ther 2011, 10:1829-1838.
    • (2011) Mol Cancer Ther , vol.10 , pp. 1829-1838
    • Waldron, N.N.1    Kaufman, D.S.2    Oh, S.3    Inde, Z.4    Hexum, M.K.5    Ohlfest, J.R.6
  • 45
    • 33750313208 scopus 로고    scopus 로고
    • Cancer stem cells-perspectives on current status and future directions: AACR workshop on cancer stem cells
    • Clarke M.F., Dick J.E., Dirks P.B., Eaves C.J., Jamieson C.H., Jones D.L., et al. Cancer stem cells-perspectives on current status and future directions: AACR workshop on cancer stem cells. Cancer Res 2006, 66:9339-9344.
    • (2006) Cancer Res , vol.66 , pp. 9339-9344
    • Clarke, M.F.1    Dick, J.E.2    Dirks, P.B.3    Eaves, C.J.4    Jamieson, C.H.5    Jones, D.L.6
  • 46
    • 84924656152 scopus 로고    scopus 로고
    • Cancer stem cell: fundamental experimental pathological concepts and updates
    • Islam F., Qiao B., Smith R.A., Gopalan V., Lam A.K. Cancer stem cell: fundamental experimental pathological concepts and updates. Exp Mol Pathol 2015, 98:184-191.
    • (2015) Exp Mol Pathol , vol.98 , pp. 184-191
    • Islam, F.1    Qiao, B.2    Smith, R.A.3    Gopalan, V.4    Lam, A.K.5
  • 47
    • 79959590586 scopus 로고    scopus 로고
    • Tumor initiating cells in esophageal squamous cell carcinomas express high levels of CD44
    • Zhao J.S., Li W.J., Ge D., Zhang P.J., Li J.J., Lu C.L., et al. Tumor initiating cells in esophageal squamous cell carcinomas express high levels of CD44. PLoS One 2011, 6:e21419.
    • (2011) PLoS One , vol.6 , pp. e21419
    • Zhao, J.S.1    Li, W.J.2    Ge, D.3    Zhang, P.J.4    Li, J.J.5    Lu, C.L.6
  • 49
    • 33845951437 scopus 로고    scopus 로고
    • Hyaluronan constitutively regulates activation of multiple receptor tyrosine kinases in epithelial and carcinoma cells
    • Misra S., Toole B.P., Ghatak S. Hyaluronan constitutively regulates activation of multiple receptor tyrosine kinases in epithelial and carcinoma cells. J Biol Chem 2006, 281:34936-34941.
    • (2006) J Biol Chem , vol.281 , pp. 34936-34941
    • Misra, S.1    Toole, B.P.2    Ghatak, S.3
  • 50
    • 0034024811 scopus 로고    scopus 로고
    • Expression of CD44 variants and prognosis in oesophageal squamous cell carcinoma
    • Gotoda T., Matsumura Y., Kondo H., Ono H., Kanamoto A., Kato H., et al. Expression of CD44 variants and prognosis in oesophageal squamous cell carcinoma. Gut 2000, 46:14-19.
    • (2000) Gut , vol.46 , pp. 14-19
    • Gotoda, T.1    Matsumura, Y.2    Kondo, H.3    Ono, H.4    Kanamoto, A.5    Kato, H.6
  • 51
    • 0032951097 scopus 로고    scopus 로고
    • Expression of epidermal growth factor receptor and CD44 splicing variants sharing exons 6 and 9 on gastric and esophageal carcinomas: a two-color flow-cytometric analysis
    • Koyama S., Maruyama T., Adachi S. Expression of epidermal growth factor receptor and CD44 splicing variants sharing exons 6 and 9 on gastric and esophageal carcinomas: a two-color flow-cytometric analysis. J Cancer Res Clin Oncol 1999, 125:47-54.
    • (1999) J Cancer Res Clin Oncol , vol.125 , pp. 47-54
    • Koyama, S.1    Maruyama, T.2    Adachi, S.3
  • 52
    • 70350774077 scopus 로고    scopus 로고
    • The relationship between cyclooxygenase-2, CD44v6, and nm23H1 in esophageal squamous cell carcinoma
    • Liu W.K., Fu Q., Li Y.M., Jiang X.Y., Zhang M.P., Zhang Z.X. The relationship between cyclooxygenase-2, CD44v6, and nm23H1 in esophageal squamous cell carcinoma. Onkologie 2009, 32:574-578.
    • (2009) Onkologie , vol.32 , pp. 574-578
    • Liu, W.K.1    Fu, Q.2    Li, Y.M.3    Jiang, X.Y.4    Zhang, M.P.5    Zhang, Z.X.6
  • 54
    • 79960936439 scopus 로고    scopus 로고
    • Cancer stem cells in squamous cell carcinoma switch between two distinct phenotypes that are preferentially migratory or proliferative
    • Biddle A., Liang X., Gammon L., Fazil B., Harper L.J., Emich H., et al. Cancer stem cells in squamous cell carcinoma switch between two distinct phenotypes that are preferentially migratory or proliferative. Cancer Res 2011, 71:5317-5326.
    • (2011) Cancer Res , vol.71 , pp. 5317-5326
    • Biddle, A.1    Liang, X.2    Gammon, L.3    Fazil, B.4    Harper, L.J.5    Emich, H.6
  • 55
    • 84864746741 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and mesenchymal-epithelial transition are essential for the acquisition of stem cell properties in hTERT-immortalised oral epithelial cells
    • Qiao B., Gopalan V., Chen Z., Smith R.A., Tao Q., Lam A.K.Y. Epithelial-mesenchymal transition and mesenchymal-epithelial transition are essential for the acquisition of stem cell properties in hTERT-immortalised oral epithelial cells. Bio Cell 2012, 104:476-489.
    • (2012) Bio Cell , vol.104 , pp. 476-489
    • Qiao, B.1    Gopalan, V.2    Chen, Z.3    Smith, R.A.4    Tao, Q.5    Lam, A.K.Y.6
  • 56
    • 33746846201 scopus 로고    scopus 로고
    • Inhibition of aldehyde dehydrogenase and retinoid signaling induces the expansion of human hematopoietic stem cells
    • Chute J.P., Muramoto G.G., Whitesides J., Colvin M., Safi R., Chao N.J., et al. Inhibition of aldehyde dehydrogenase and retinoid signaling induces the expansion of human hematopoietic stem cells. Proc Natl Acad Sci U S A 2006, 103:11707-11712.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 11707-11712
    • Chute, J.P.1    Muramoto, G.G.2    Whitesides, J.3    Colvin, M.4    Safi, R.5    Chao, N.J.6
  • 57
    • 33344468146 scopus 로고    scopus 로고
    • Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells
    • Hess D.A., Wirthlin L., Craft T.P., Herrbrich P.E., Hohm S.A., Lahey R., et al. Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells. Blood 2006, 107:2162-2169.
    • (2006) Blood , vol.107 , pp. 2162-2169
    • Hess, D.A.1    Wirthlin, L.2    Craft, T.P.3    Herrbrich, P.E.4    Hohm, S.A.5    Lahey, R.6
  • 58
    • 84882944107 scopus 로고    scopus 로고
    • A new method for identifying stem-like cells in esophageal cancer cell lines
    • Almanaa T.N., Geusz M.E., Jamasbi R.J. A new method for identifying stem-like cells in esophageal cancer cell lines. J Cancer 2013, 4:536-548.
    • (2013) J Cancer , vol.4 , pp. 536-548
    • Almanaa, T.N.1    Geusz, M.E.2    Jamasbi, R.J.3
  • 59
    • 84862263486 scopus 로고    scopus 로고
    • Expression analysis elucidates the roles of MAML1 and Twist1 in esophageal squamous cell carcinoma aggressiveness and metastasis
    • Forghanifard M.M., Moaven O., Farshchian M., Montazer M., Raeisossadati R., Abdollahi A., et al. Expression analysis elucidates the roles of MAML1 and Twist1 in esophageal squamous cell carcinoma aggressiveness and metastasis. Ann Surg Oncol 2012, 19:743-749.
    • (2012) Ann Surg Oncol , vol.19 , pp. 743-749
    • Forghanifard, M.M.1    Moaven, O.2    Farshchian, M.3    Montazer, M.4    Raeisossadati, R.5    Abdollahi, A.6
  • 61
    • 84898828823 scopus 로고    scopus 로고
    • Clinicopathological sex-related relevance of Musashi1 mRNA expression in esophageal squamous cell carcinoma patients
    • Moghbeli M., Forghanifard M.M., Aarabi A., Mansourian A., Abbaszadegan M.R. Clinicopathological sex-related relevance of Musashi1 mRNA expression in esophageal squamous cell carcinoma patients. Pathol Oncol Res 2014, 20:427-433.
    • (2014) Pathol Oncol Res , vol.20 , pp. 427-433
    • Moghbeli, M.1    Forghanifard, M.M.2    Aarabi, A.3    Mansourian, A.4    Abbaszadegan, M.R.5
  • 63
    • 48349133869 scopus 로고    scopus 로고
    • Side population cells in human cancers
    • Wu C., Alman B.A. Side population cells in human cancers. Cancer Lett 2008, 268:1-9.
    • (2008) Cancer Lett , vol.268 , pp. 1-9
    • Wu, C.1    Alman, B.A.2
  • 64
    • 65349130616 scopus 로고    scopus 로고
    • Isolation and identification of cancer stem-like cells in esophageal carcinoma cell lines
    • Huang D., Gao Q., Guo L., Zhang C., Jiang W., Li H., et al. Isolation and identification of cancer stem-like cells in esophageal carcinoma cell lines. Stem Cells Dev 2009, 18:465-473.
    • (2009) Stem Cells Dev , vol.18 , pp. 465-473
    • Huang, D.1    Gao, Q.2    Guo, L.3    Zhang, C.4    Jiang, W.5    Li, H.6
  • 65
    • 79957846955 scopus 로고    scopus 로고
    • The EN/PI3K/Akt pathway regulates stem-like cells in primary esophageal carcinoma cells
    • Li H., Gao Q., Guo L., Lu S.H. The EN/PI3K/Akt pathway regulates stem-like cells in primary esophageal carcinoma cells. Cancer Biol Ther 2011, 11:950-958.
    • (2011) Cancer Biol Ther , vol.11 , pp. 950-958
    • Li, H.1    Gao, Q.2    Guo, L.3    Lu, S.H.4
  • 66
    • 33749004013 scopus 로고    scopus 로고
    • The biological role of the low-affinity p75 neurotrophin receptor in esophageal squamous cell carcinoma
    • Okumura T., Tsunoda S., Mori Y., Ito T., Kikuchi K., Wang T.C., et al. The biological role of the low-affinity p75 neurotrophin receptor in esophageal squamous cell carcinoma. Clin Cancer Res 2006, 12:5096-5103.
    • (2006) Clin Cancer Res , vol.12 , pp. 5096-5103
    • Okumura, T.1    Tsunoda, S.2    Mori, Y.3    Ito, T.4    Kikuchi, K.5    Wang, T.C.6
  • 67
    • 0038001274 scopus 로고    scopus 로고
    • Neurotrophin receptor p75 (NTR) characterizes human esophageal keratinocyte stem cells in vitro
    • Okumura T., Shimada Y., Imamura M., Yasumoto S. Neurotrophin receptor p75 (NTR) characterizes human esophageal keratinocyte stem cells in vitro. Oncogene 2003, 22:4017-4026.
    • (2003) Oncogene , vol.22 , pp. 4017-4026
    • Okumura, T.1    Shimada, Y.2    Imamura, M.3    Yasumoto, S.4
  • 68
    • 84862317152 scopus 로고    scopus 로고
    • CD90 is identified as a candidate marker for cancer stem cells in primary high-grade gliomas using tissue microarrays
    • [M111.010744]
    • He J., Liu Y., Zhu T., Zhu J., Dimeco F., Vescovi A.L., et al. CD90 is identified as a candidate marker for cancer stem cells in primary high-grade gliomas using tissue microarrays. Mol Cell Proteomics 2012, 11. [M111.010744].
    • (2012) Mol Cell Proteomics , vol.11
    • He, J.1    Liu, Y.2    Zhu, T.3    Zhu, J.4    Dimeco, F.5    Vescovi, A.L.6
  • 69
    • 84875981178 scopus 로고    scopus 로고
    • A CD90 tumor-initiating cell population with an aggressive signature and metastatic capacity in esophageal cancer
    • Tang K.H., Dai Y.D., Tong M., Chan Y.P., Kwan P.S., Fu L., et al. A CD90 tumor-initiating cell population with an aggressive signature and metastatic capacity in esophageal cancer. Cancer Res 2013, 73:2322-2332.
    • (2013) Cancer Res , vol.73 , pp. 2322-2332
    • Tang, K.H.1    Dai, Y.D.2    Tong, M.3    Chan, Y.P.4    Kwan, P.S.5    Fu, L.6
  • 70
    • 79952370202 scopus 로고    scopus 로고
    • The cancer stem cell: premises, promises and challenges
    • Clevers H. The cancer stem cell: premises, promises and challenges. Nat Med 2011, 17:313-319.
    • (2011) Nat Med , vol.17 , pp. 313-319
    • Clevers, H.1
  • 71
    • 0034767957 scopus 로고    scopus 로고
    • Cancer burden in the year 2000. The global picture
    • Parkin D.M., Bray F.I., Devesa S.S. Cancer burden in the year 2000. The global picture. Eur J Cancer 2001, 37:54-66.
    • (2001) Eur J Cancer , vol.37 , pp. 54-66
    • Parkin, D.M.1    Bray, F.I.2    Devesa, S.S.3
  • 72
    • 79961126637 scopus 로고    scopus 로고
    • Gastric cancer stem-like cells possess higher capability of invasion and metastasis in association with a mesenchymal transition phenotype
    • Yang L., Ping Y.F., Yu X., Qian F., Guo Z.J., Qian C., et al. Gastric cancer stem-like cells possess higher capability of invasion and metastasis in association with a mesenchymal transition phenotype. Cancer Lett 2011, 310:46-52.
    • (2011) Cancer Lett , vol.310 , pp. 46-52
    • Yang, L.1    Ping, Y.F.2    Yu, X.3    Qian, F.4    Guo, Z.J.5    Qian, C.6
  • 73
    • 70349157505 scopus 로고    scopus 로고
    • Enrichment of cancer stem cells based on heterogeneity of invasiveness
    • Yu S.C., Bian X.W. Enrichment of cancer stem cells based on heterogeneity of invasiveness. Stem Cell Rev 2009, 5:66-71.
    • (2009) Stem Cell Rev , vol.5 , pp. 66-71
    • Yu, S.C.1    Bian, X.W.2
  • 74
    • 84862879740 scopus 로고    scopus 로고
    • Tumor-associated microglia/macrophages enhance the invasion of glioma stem-like cells via TGF-beta1 signaling pathway
    • Ye X.Z., Xu S.L., Xin Y.H., Yu S.C., Ping Y.F., Chen L., et al. Tumor-associated microglia/macrophages enhance the invasion of glioma stem-like cells via TGF-beta1 signaling pathway. J Immunol 2012, 189:444-453.
    • (2012) J Immunol , vol.189 , pp. 444-453
    • Ye, X.Z.1    Xu, S.L.2    Xin, Y.H.3    Yu, S.C.4    Ping, Y.F.5    Chen, L.6
  • 75
    • 84899983111 scopus 로고    scopus 로고
    • ALDH1A1 defines invasive cancer stem-like cells and predicts poor prognosis in patients with esophageal squamous cell carcinoma
    • Yang L., Ren Y., Yu X., Qian F., Bian B.S., Xiao H.L., et al. ALDH1A1 defines invasive cancer stem-like cells and predicts poor prognosis in patients with esophageal squamous cell carcinoma. Mod Pathol 2014, 27:775-783.
    • (2014) Mod Pathol , vol.27 , pp. 775-783
    • Yang, L.1    Ren, Y.2    Yu, X.3    Qian, F.4    Bian, B.S.5    Xiao, H.L.6
  • 76
    • 84864994388 scopus 로고    scopus 로고
    • Cancer stem cell marker ALDH1 expression is associated with lymph node metastasis and poor survival in esophageal squamous cell carcinoma: a study from high incidence area of northern China
    • Wang Y., Zhe H., Gao P., Zhang N., Li G., Qin J. Cancer stem cell marker ALDH1 expression is associated with lymph node metastasis and poor survival in esophageal squamous cell carcinoma: a study from high incidence area of northern China. Dis Esophagus 2012, 25:560-565.
    • (2012) Dis Esophagus , vol.25 , pp. 560-565
    • Wang, Y.1    Zhe, H.2    Gao, P.3    Zhang, N.4    Li, G.5    Qin, J.6
  • 77
    • 84940248392 scopus 로고    scopus 로고
    • A retrospective review of the prognostic value of ALDH-1. Bmi-1 and Nanog stem cell markers in esophageal squamous cell carcinoma
    • Hwang C.C., Nieh S., Lai C.H., Tsai C.S., Chang L.C., Hua C.C., et al. A retrospective review of the prognostic value of ALDH-1. Bmi-1 and Nanog stem cell markers in esophageal squamous cell carcinoma. PLoS One 2014, 9:e105676.
    • (2014) PLoS One , vol.9 , pp. e105676
    • Hwang, C.C.1    Nieh, S.2    Lai, C.H.3    Tsai, C.S.4    Chang, L.C.5    Hua, C.C.6
  • 78
    • 84871802319 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1 expression is associated with poor prognosis in patients with esophageal squamous cell carcinoma
    • Minato T., Yamamoto Y., Seike J., Yoshida T., Yamai H., Takechi H., et al. Aldehyde dehydrogenase 1 expression is associated with poor prognosis in patients with esophageal squamous cell carcinoma. Ann Surg Oncol 2013, 20:209-217.
    • (2013) Ann Surg Oncol , vol.20 , pp. 209-217
    • Minato, T.1    Yamamoto, Y.2    Seike, J.3    Yoshida, T.4    Yamai, H.5    Takechi, H.6
  • 79
    • 0037030522 scopus 로고    scopus 로고
    • Molecular characterization of hiwi, a human member of the piwi gene family whose overexpression is correlated to seminomas
    • Qiao D., Zeeman A.M., Deng W., Looijenga L.H., Lin H. Molecular characterization of hiwi, a human member of the piwi gene family whose overexpression is correlated to seminomas. Oncogene 2002, 21:3988-3999.
    • (2002) Oncogene , vol.21 , pp. 3988-3999
    • Qiao, D.1    Zeeman, A.M.2    Deng, W.3    Looijenga, L.H.4    Lin, H.5
  • 80
    • 74049085017 scopus 로고    scopus 로고
    • Expression of HIWI in human esophageal squamous cell carcinoma is significantly associated with poorer prognosis
    • He W., Wang Z., Wang Q., Fan Q., Shou C., Wang J., et al. Expression of HIWI in human esophageal squamous cell carcinoma is significantly associated with poorer prognosis. BMC Cancer 2009, 9:426.
    • (2009) BMC Cancer , vol.9 , pp. 426
    • He, W.1    Wang, Z.2    Wang, Q.3    Fan, Q.4    Shou, C.5    Wang, J.6
  • 81
    • 0034028901 scopus 로고    scopus 로고
    • Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
    • Niwa H., Miyazaki J., Smith A.G. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet 2000, 24:372-376.
    • (2000) Nat Genet , vol.24 , pp. 372-376
    • Niwa, H.1    Miyazaki, J.2    Smith, A.G.3
  • 82
    • 20344364163 scopus 로고    scopus 로고
    • Oct-3/4 maintains the proliferative embryonic stem cell state via specific binding to a variant octamer sequence in the regulatory region of the UTF1 locus
    • Nishimoto M., Miyagi S., Yamagishi T., Sakaguchi T., Niwa H., Muramatsu M., et al. Oct-3/4 maintains the proliferative embryonic stem cell state via specific binding to a variant octamer sequence in the regulatory region of the UTF1 locus. Mol Cell Biol 2005, 25:5084-5094.
    • (2005) Mol Cell Biol , vol.25 , pp. 5084-5094
    • Nishimoto, M.1    Miyagi, S.2    Yamagishi, T.3    Sakaguchi, T.4    Niwa, H.5    Muramatsu, M.6
  • 83
    • 64949085479 scopus 로고    scopus 로고
    • Oct 3/4 and SOX2 are significantly associated with an unfavorable clinical outcome in human esophageal squamous cell carcinoma
    • Wang Q., He W., Lu C., Wang Z., Wang J., Giercksky K.E., et al. Oct 3/4 and SOX2 are significantly associated with an unfavorable clinical outcome in human esophageal squamous cell carcinoma. Anticancer Res 2009, 29:1233-1241.
    • (2009) Anticancer Res , vol.29 , pp. 1233-1241
    • Wang, Q.1    He, W.2    Lu, C.3    Wang, Z.4    Wang, J.5    Giercksky, K.E.6
  • 84
    • 79960604772 scopus 로고    scopus 로고
    • Over-expression of Oct 4 in human esophageal squamous cell carcinoma
    • Zhou X., Huang G.R., Hu P. Over-expression of Oct 4 in human esophageal squamous cell carcinoma. Mol Cells 2011, 32:39-45.
    • (2011) Mol Cells , vol.32 , pp. 39-45
    • Zhou, X.1    Huang, G.R.2    Hu, P.3
  • 85
    • 0037520693 scopus 로고    scopus 로고
    • Stem cell pluripotency and transcription factor Oct 4
    • Pan G.J., Chang Z.Y., Scholer H.R., Pei D. Stem cell pluripotency and transcription factor Oct 4. Cell Res 2002, 12:321-329.
    • (2002) Cell Res , vol.12 , pp. 321-329
    • Pan, G.J.1    Chang, Z.Y.2    Scholer, H.R.3    Pei, D.4
  • 86
    • 59049084011 scopus 로고    scopus 로고
    • Physiological and pharmacological roles of ABCG2 (BCRP): recent findings in Abcg2 knockout mice
    • Vlaming M.L., Lagas J.S., Schinkel A.H. Physiological and pharmacological roles of ABCG2 (BCRP): recent findings in Abcg2 knockout mice. Adv Drug Deliv Rev 2009, 61:14-25.
    • (2009) Adv Drug Deliv Rev , vol.61 , pp. 14-25
    • Vlaming, M.L.1    Lagas, J.S.2    Schinkel, A.H.3
  • 87
    • 84861018126 scopus 로고    scopus 로고
    • Prognostic value of the stem cell markers CD133 and ABCG2 expression in esophageal squamous cell carcinoma
    • Hang D., Dong H.C., Ning T., Dong B., Hou D.L., Xu W.G. Prognostic value of the stem cell markers CD133 and ABCG2 expression in esophageal squamous cell carcinoma. Dis Esophagus 2012, 25:638-644.
    • (2012) Dis Esophagus , vol.25 , pp. 638-644
    • Hang, D.1    Dong, H.C.2    Ning, T.3    Dong, B.4    Hou, D.L.5    Xu, W.G.6
  • 88
    • 34548071672 scopus 로고    scopus 로고
    • ABCG2 expression is an independent unfavorable prognostic factor in esophageal squamous cell carcinoma
    • Tsunoda S., Okumura T., Ito T., Kondo K., Ortiz C., Tanaka E., et al. ABCG2 expression is an independent unfavorable prognostic factor in esophageal squamous cell carcinoma. Oncology 2006, 71:251-258.
    • (2006) Oncology , vol.71 , pp. 251-258
    • Tsunoda, S.1    Okumura, T.2    Ito, T.3    Kondo, K.4    Ortiz, C.5    Tanaka, E.6
  • 89
    • 77955640829 scopus 로고    scopus 로고
    • SOX2 and Oct-3/4: a versatile pair of master regulators that orchestrate the self-renewal and pluripotency of embryonic stem cells
    • Rizzino A. SOX2 and Oct-3/4: a versatile pair of master regulators that orchestrate the self-renewal and pluripotency of embryonic stem cells. Wiley Interdiscip Rev Syst Biol Med 2009, 1:228-236.
    • (2009) Wiley Interdiscip Rev Syst Biol Med , vol.1 , pp. 228-236
    • Rizzino, A.1
  • 90
    • 84891792702 scopus 로고    scopus 로고
    • Two novel splice variants of SOX2OT, SOX2OT-S1, and SOX2OT-S2 are coupregulated with SOX2 and Oct 4 in esophageal squamous cell carcinoma
    • Shahryari A., Rafiee M.R., Fouani Y., Oliae N.A., Samaei N.M., Shafiee M., et al. Two novel splice variants of SOX2OT, SOX2OT-S1, and SOX2OT-S2 are coupregulated with SOX2 and Oct 4 in esophageal squamous cell carcinoma. Stem Cells 2014, 32:126-134.
    • (2014) Stem Cells , vol.32 , pp. 126-134
    • Shahryari, A.1    Rafiee, M.R.2    Fouani, Y.3    Oliae, N.A.4    Samaei, N.M.5    Shafiee, M.6
  • 91
    • 80053168039 scopus 로고    scopus 로고
    • Podoplanin and SOX2 expression in esophageal squamous cell carcinoma after neoadjuvant chemo-radiotherapy
    • Saigusa S., Mohri Y., Ohi M., Toiyama Y., Ishino Y., Okugawa Y., et al. Podoplanin and SOX2 expression in esophageal squamous cell carcinoma after neoadjuvant chemo-radiotherapy. Oncol Rep 2011, 26:1069-1074.
    • (2011) Oncol Rep , vol.26 , pp. 1069-1074
    • Saigusa, S.1    Mohri, Y.2    Ohi, M.3    Toiyama, Y.4    Ishino, Y.5    Okugawa, Y.6
  • 92
    • 77957065335 scopus 로고    scopus 로고
    • SOX2 identified as a target gene for the amplification at 3q26 that is frequently detected in esophageal squamous cell carcinoma
    • Gen Y., Yasui K., Zen Y., Zen K., Dohi O., Endo M., et al. SOX2 identified as a target gene for the amplification at 3q26 that is frequently detected in esophageal squamous cell carcinoma. Cancer Genet Cytogenet 2010, 202:82-93.
    • (2010) Cancer Genet Cytogenet , vol.202 , pp. 82-93
    • Gen, Y.1    Yasui, K.2    Zen, Y.3    Zen, K.4    Dohi, O.5    Endo, M.6
  • 93
    • 84896417983 scopus 로고    scopus 로고
    • Stemness state regulators SALL4 and SOX2 are involved in progression and invasiveness of esophageal squamous cell carcinoma
    • Forghanifard M.M., Ardalan Khales S., Javdani-Mallak A., Rad A., Farshchian M., Abbaszadegan M.R. Stemness state regulators SALL4 and SOX2 are involved in progression and invasiveness of esophageal squamous cell carcinoma. Med Oncol 2014, 31:922.
    • (2014) Med Oncol , vol.31 , pp. 922
    • Forghanifard, M.M.1    Ardalan Khales, S.2    Javdani-Mallak, A.3    Rad, A.4    Farshchian, M.5    Abbaszadegan, M.R.6
  • 94
    • 84879129284 scopus 로고    scopus 로고
    • BMI-1 activation is crucial in HTERT-induced epithelial-mesenchymal transition of oral epithelial cells
    • Qiao B., Chen Z., Hu F., Tao Q., Lam A.K. BMI-1 activation is crucial in HTERT-induced epithelial-mesenchymal transition of oral epithelial cells. Exp Mol Pathol 2013, 95:57-61.
    • (2013) Exp Mol Pathol , vol.95 , pp. 57-61
    • Qiao, B.1    Chen, Z.2    Hu, F.3    Tao, Q.4    Lam, A.K.5
  • 95
    • 84857497457 scopus 로고    scopus 로고
    • Role of BMI1, a stem cell factor, in cancer recurrence and chemoresistance: preclinical and clinical evidences
    • Siddique H.R., Saleem M. Role of BMI1, a stem cell factor, in cancer recurrence and chemoresistance: preclinical and clinical evidences. Stem Cells 2012, 30:372-378.
    • (2012) Stem Cells , vol.30 , pp. 372-378
    • Siddique, H.R.1    Saleem, M.2
  • 96
    • 84867127629 scopus 로고    scopus 로고
    • The oncoprotein and stem cell renewal factor BMI1 associates with poor clinical outcome in oesophageal cancer patients undergoing preoperative chemoradiotherapy
    • Yoshikawa R., Tsujimura T., Tao L., Kamikonya N., Fujiwara Y. The oncoprotein and stem cell renewal factor BMI1 associates with poor clinical outcome in oesophageal cancer patients undergoing preoperative chemoradiotherapy. BMC Cancer 2012, 12:461.
    • (2012) BMC Cancer , vol.12 , pp. 461
    • Yoshikawa, R.1    Tsujimura, T.2    Tao, L.3    Kamikonya, N.4    Fujiwara, Y.5
  • 97
    • 0037806031 scopus 로고    scopus 로고
    • The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
    • Mitsui K., Tokuzawa Y., Itoh H., Segawa K., Murakami M., Takahashi K., et al. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 2003, 113:631-642.
    • (2003) Cell , vol.113 , pp. 631-642
    • Mitsui, K.1    Tokuzawa, Y.2    Itoh, H.3    Segawa, K.4    Murakami, M.5    Takahashi, K.6
  • 98
    • 84872574289 scopus 로고    scopus 로고
    • Expression analysis of iPS cell-inductive genes in esophageal squamous cell carcinoma by tissue microarray
    • Shimada Y., Okumura T., Sekine S., Moriyama M., Sawada S., Matsui K., et al. Expression analysis of iPS cell-inductive genes in esophageal squamous cell carcinoma by tissue microarray. Anticancer Res 2012, 32:5507-5514.
    • (2012) Anticancer Res , vol.32 , pp. 5507-5514
    • Shimada, Y.1    Okumura, T.2    Sekine, S.3    Moriyama, M.4    Sawada, S.5    Matsui, K.6
  • 99
    • 84964285764 scopus 로고    scopus 로고
    • A three-gene signature and clinical outcome in esophageal squamous cell carcinoma
    • Sun L.L., Wu J.Y., Wu Z.Y., Shen J.H., Xu X.E., Chen B., et al. A three-gene signature and clinical outcome in esophageal squamous cell carcinoma. Int J Cancer 2015, 136:E569-E577.
    • (2015) Int J Cancer , vol.136 , pp. E569-E577
    • Sun, L.L.1    Wu, J.Y.2    Wu, Z.Y.3    Shen, J.H.4    Xu, X.E.5    Chen, B.6
  • 100
    • 45749102020 scopus 로고    scopus 로고
    • CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors
    • Shmelkov S.V., Butler J.M., Hooper A.T., Hormigo A., Kushner J., Milde T. CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors. J Clin Invest 2008, 118:2111-2120.
    • (2008) J Clin Invest , vol.118 , pp. 2111-2120
    • Shmelkov, S.V.1    Butler, J.M.2    Hooper, A.T.3    Hormigo, A.4    Kushner, J.5    Milde, T.6
  • 101
    • 84888860467 scopus 로고    scopus 로고
    • Isolation, identification and expression of specific human CD133 antibodies
    • Xia J., Zhang Y., Qian J., Zhu X., Zhang Y., Zhang J., et al. Isolation, identification and expression of specific human CD133 antibodies. Sci Rep 2013, 3:3320.
    • (2013) Sci Rep , vol.3 , pp. 3320
    • Xia, J.1    Zhang, Y.2    Qian, J.3    Zhu, X.4    Zhang, Y.5    Zhang, J.6
  • 103
    • 0033565967 scopus 로고    scopus 로고
    • Cloning and characterization of gp36, a human mucin-type glycoprotein preferentially expressed in vascular endothelium
    • Zimmer G., Oeffner F., Von Messling V., Tschernig T., Gröness H.J., Klenk H.D., et al. Cloning and characterization of gp36, a human mucin-type glycoprotein preferentially expressed in vascular endothelium. Biochem J 1999, 341:277-284.
    • (1999) Biochem J , vol.341 , pp. 277-284
    • Zimmer, G.1    Oeffner, F.2    Von Messling, V.3    Tschernig, T.4    Gröness, H.J.5    Klenk, H.D.6
  • 104
    • 84906014874 scopus 로고    scopus 로고
    • Podoplanin: a novel regulator of tumor invasion and metastasis
    • Dang Q., Liu J., Li J., Sun Y. Podoplanin: a novel regulator of tumor invasion and metastasis. Med Oncol 2014, 31:24.
    • (2014) Med Oncol , vol.31 , pp. 24
    • Dang, Q.1    Liu, J.2    Li, J.3    Sun, Y.4
  • 105
    • 84902484525 scopus 로고    scopus 로고
    • Clinicopathology significance of podoplanin immunoreactivity in esophageal squamous cell carcinoma
    • Ma W., Wang K., Yang S., Wang J., Tan B., Bai B., et al. Clinicopathology significance of podoplanin immunoreactivity in esophageal squamous cell carcinoma. Int J Clin Exp Pathol 2014, 7:2361-2371.
    • (2014) Int J Clin Exp Pathol , vol.7 , pp. 2361-2371
    • Ma, W.1    Wang, K.2    Yang, S.3    Wang, J.4    Tan, B.5    Bai, B.6
  • 106
    • 84855357168 scopus 로고    scopus 로고
    • Prognostic significance of high podoplanin expression after chemoradiotherapy in esophageal squamous cell carcinoma patients
    • Chao Y.K., Chuang W.Y., Yeh C.J., Wu Y.C., Liu Y.H., Hsieh M.J., et al. Prognostic significance of high podoplanin expression after chemoradiotherapy in esophageal squamous cell carcinoma patients. J Surg Oncol 2012, 105:183-188.
    • (2012) J Surg Oncol , vol.105 , pp. 183-188
    • Chao, Y.K.1    Chuang, W.Y.2    Yeh, C.J.3    Wu, Y.C.4    Liu, Y.H.5    Hsieh, M.J.6
  • 107
    • 84855770033 scopus 로고    scopus 로고
    • Role of podoplanin expression in esophageal squamous cell carcinoma: a retrospective study
    • Tong L., Yuan S., Feng F., Zhang H. Role of podoplanin expression in esophageal squamous cell carcinoma: a retrospective study. Dis Esophagus 2012, 25:72-80.
    • (2012) Dis Esophagus , vol.25 , pp. 72-80
    • Tong, L.1    Yuan, S.2    Feng, F.3    Zhang, H.4
  • 108
    • 77952090143 scopus 로고    scopus 로고
    • Tumorigenic role of podoplanin in esophageal squamous-cell carcinoma
    • Rahadiani N., Ikeda J., Makino T., Tian T., Qiu Y., Mamat S., et al. Tumorigenic role of podoplanin in esophageal squamous-cell carcinoma. Ann Surg Oncol 2010, 17:1311-1323.
    • (2010) Ann Surg Oncol , vol.17 , pp. 1311-1323
    • Rahadiani, N.1    Ikeda, J.2    Makino, T.3    Tian, T.4    Qiu, Y.5    Mamat, S.6
  • 109
    • 69149103535 scopus 로고    scopus 로고
    • Tumor cell expression of podoplanin correlates with nodal metastasis in esophageal squamous cell carcinoma
    • Chuang W.Y., Yeh C.J., Wu Y.C., Chao Y.K., Liu Y.H., Tseng C.K., et al. Tumor cell expression of podoplanin correlates with nodal metastasis in esophageal squamous cell carcinoma. Histol Histopathol 2009, 24:1021-1027.
    • (2009) Histol Histopathol , vol.24 , pp. 1021-1027
    • Chuang, W.Y.1    Yeh, C.J.2    Wu, Y.C.3    Chao, Y.K.4    Liu, Y.H.5    Tseng, C.K.6
  • 110
    • 80053144962 scopus 로고    scopus 로고
    • A decade of exploring the cancer epigenome-biological and translational implications
    • Baylin S.B., Jones P.A. A decade of exploring the cancer epigenome-biological and translational implications. Nat Rev Cancer 2011, 11:726-734.
    • (2011) Nat Rev Cancer , vol.11 , pp. 726-734
    • Baylin, S.B.1    Jones, P.A.2
  • 112
    • 84879983245 scopus 로고    scopus 로고
    • Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity
    • Chaffer C.L., Marjanovic N.D., Lee T., Bell G., Kleer C.G., Reinhardt F., et al. Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity. Cell 2013, 154:61-74.
    • (2013) Cell , vol.154 , pp. 61-74
    • Chaffer, C.L.1    Marjanovic, N.D.2    Lee, T.3    Bell, G.4    Kleer, C.G.5    Reinhardt, F.6
  • 114
    • 84860342715 scopus 로고    scopus 로고
    • Pancreatic stellate cells form a niche for cancer stem cells and promote their self-renewal and invasiveness
    • Lonardo E., Frias-Aldeguer J., Hermann P.C., Heeschen C. Pancreatic stellate cells form a niche for cancer stem cells and promote their self-renewal and invasiveness. Cell Cycle 2012, 11:1282-1290.
    • (2012) Cell Cycle , vol.11 , pp. 1282-1290
    • Lonardo, E.1    Frias-Aldeguer, J.2    Hermann, P.C.3    Heeschen, C.4
  • 115
    • 78751522709 scopus 로고    scopus 로고
    • Breast cancer stem cells are regulated by mesenchymal stem cells through cytokine networks
    • Liu S., Ginestier C., Ou S.J., Clouthier S.G., Patel S.H., Monville F., et al. Breast cancer stem cells are regulated by mesenchymal stem cells through cytokine networks. Cancer Res 2011, 71:614-624.
    • (2011) Cancer Res , vol.71 , pp. 614-624
    • Liu, S.1    Ginestier, C.2    Ou, S.J.3    Clouthier, S.G.4    Patel, S.H.5    Monville, F.6
  • 117
    • 84884368877 scopus 로고    scopus 로고
    • Influence of tumour micro-environment heterogeneity on therapeutic response
    • Junttila M.R., de Sauvage F.J. Influence of tumour micro-environment heterogeneity on therapeutic response. Nature 2013, 501:346-354.
    • (2013) Nature , vol.501 , pp. 346-354
    • Junttila, M.R.1    de Sauvage, F.J.2
  • 118
    • 84876489727 scopus 로고    scopus 로고
    • Cancer stem cells: the challenges ahead
    • Medema J.P. Cancer stem cells: the challenges ahead. Nat Cell Biol 2013, 15:338-344.
    • (2013) Nat Cell Biol , vol.15 , pp. 338-344
    • Medema, J.P.1
  • 120
    • 66949150208 scopus 로고    scopus 로고
    • Targeting stem cells-clinical implications for cancer therapy
    • Tu L.C., Foltz G., Lin E., Hood L., Tian Q. Targeting stem cells-clinical implications for cancer therapy. Curr Stem Cell Res Ther 2009, 4:147-153.
    • (2009) Curr Stem Cell Res Ther , vol.4 , pp. 147-153
    • Tu, L.C.1    Foltz, G.2    Lin, E.3    Hood, L.4    Tian, Q.5
  • 121
    • 79957989939 scopus 로고    scopus 로고
    • Drug discovery approaches to target Wnt signaling in cancer stem cells
    • Curtin J.C., Lorenzi M.V. Drug discovery approaches to target Wnt signaling in cancer stem cells. Oncotarget 2010, 1:563-577.
    • (2010) Oncotarget , vol.1 , pp. 563-577
    • Curtin, J.C.1    Lorenzi, M.V.2
  • 123
    • 79551600015 scopus 로고    scopus 로고
    • Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways
    • Takebe N., Harris P.J., Warren R.Q., Ivy S.P. Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways. Nat Rev Clin Oncol 2011, 8:97-106.
    • (2011) Nat Rev Clin Oncol , vol.8 , pp. 97-106
    • Takebe, N.1    Harris, P.J.2    Warren, R.Q.3    Ivy, S.P.4
  • 124
    • 84861995326 scopus 로고    scopus 로고
    • Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells
    • Sachlos E., Risueño R.M., Laronde S., Shapovalova Z., Lee J.H., Russell J., et al. Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells. Cell 2012, 149:1284-1297.
    • (2012) Cell , vol.149 , pp. 1284-1297
    • Sachlos, E.1    Risueño, R.M.2    Laronde, S.3    Shapovalova, Z.4    Lee, J.H.5    Russell, J.6


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