Expression analysis of iPS cell - Inductive genes in esophageal squamous cell carcinoma by tissue microarray

Anticancer Research

Volumn 32, Issue 12, 2012, Pages 5507-5514

  Shimada, Yutaka ^a   Okumura, Tomoyuki ^a   Sekine, Shinichi ^a   Moriyama, Makoto ^a   Sawada, Shigeaki ^a   Matsui, Koshi ^a   Yoshioka, Isaku ^a   Hojo, Shozo ^a   Yoshida, Toru ^a   Nagata, Takuya ^a   Fukuoka, Junya ^a   Tsukada, Kazuhiro ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

c MYC; Esophageal cancer; KLF4; NANOG; OCT 3 4; SOX2

Indexed keywords

CISPLATIN; DOXORUBICIN; FLUOROURACIL; KRUPPEL LIKE FACTOR 4; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2;

ADULT; AGED; ARTICLE; CANCER CHEMOTHERAPY; CANCER PROGNOSIS; CANCER STAGING; DISEASE ASSOCIATION; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; TISSUE MICROARRAY;

AGED; CARCINOMA, SQUAMOUS CELL; ESOPHAGEAL NEOPLASMS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HOMEODOMAIN PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; INDUCED PLURIPOTENT STEM CELLS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MALE; MIDDLE AGED; OCTAMER TRANSCRIPTION FACTOR-3; PROGNOSIS; PROTO-ONCOGENE PROTEINS C-MYC; SOXB1 TRANSCRIPTION FACTORS; TISSUE ARRAY ANALYSIS;

EID: 84872574289     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Takahashi K and Yamanaka S: Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126: 663-676, 2006.
2. Yu J, Vodyanik MA, Smuga OK Antosiewicz BJ, Frane JL, Tian S Nie J, Jonsdottir GA, Ruotti V, Stewart R, Slukvin II, and Thomson JA: Induced pluripotent stem cell lines derived from human somatic cells. Science 318: 1917-1920, 2007.
3. Okita K, Ichisaka T and Yamanaka S: Generation of germline-competent induced pluripotent stem cells. Nature 448: 313-317, 2007.
4. Aoi T, Yae K, Nakagawa M, Ichisaka T, Okita K, Takahashi K, Chiba T and Yamanaka S: Generation of pluripotent stem cells from adult mouse liver and stomach cells. Science 321: 699-702, 2008.
5. Nagata T, Shimada Y, Sekine S, Hori R, Matsui K, Okumura T, Sawada S, Fukuoka J and Tsukada K: Prognostic significance of NANOG and KLF4 for breast cancer. Breast Cancer 2012 in press. DOI 10.1007/s12282-012-0357-y
6. Du Y, Shi L, Wang T. Liu Z and Wang Z: NANOG siRNA plus Cisplatin may enhance the sensitivity of chemotherapy in esophageal cancer. J Cancer Res Clin Oncol 138(10): 1759-1767, 2012.
7. Miyoshi, N, Ishii H, Nagaia K, Hoshino H, Mimori K, Tanaka F, Nagano H, Sekimoto M, Doki Y and Mori M: Defined factors induce reprogramming of gastrointestinal cancer cells. Proc Natl Acad Sci USA 107: 40-45, 2010.
8. Wang W, Xue L and Wang P: Prognostic value of beta-catenin, c-MYC, and cyclin D1 expressions in patients with esophageal squamous cell carcinoma. Med Oncol 28: 163-69, 2011.
9. Yang S, He S, Zhou1 X, Liu M, Zhu H, Wang Y, Zhang W, Yan S, Quan L, Bai J and Xu N: Suppression of aurora-A oncogenic potential by c-MYC down-regulation. Exp Mol Med 42: 759-767, 2010.
10. Mendelson J, Song S, Li Y, Maru DM, Mishra B, Davila M, Hofstetter WL and Mishra L: Dysfunctional transforming growth factor-beta signaling with constitutively active NOTCH signaling in Barrett's esophageal adenocarcinoma. Cancer 117: 3691-3702, 2011.
11. Long KB and Hornick JL: SOX2 is highly expressed in squamous cell carcinomas of the gastrointestinal tract. Hum Pathol 40(12): 1768-1773, 2009.
12. Bass AJ, Watanabe H, Mermel CH, Yu S, Perner S, Verhaak RG, Kim SY, Wardwell L, Tamayo P, Gat-Viks I, Ramos AH, Woo MS, Weir BA, Getz G, Beroukhim R, O'Kelly M, Dutt A, Rozenblatt-Rosen O, Dziunycz P, Komisarof J, Chirieac LR, Lafargue CJ, Scheble V, Wilbertz T, Ma C, Rao S, Nakagawa H, Stairs DB, Lin L, Giordano TJ, Wagner P, Minna JD, Gazdar AF, Zhu CQ, Brose MS, Cecconello I Jr. UR, Marie SK, Dahl O, Shivdasani RA, Tsao MS, Rubin MA, Wong KK, Regev A, Hahn WC, Beer DG, Rustgi AK and Meyerson M: SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nat Genet 41: 1238-1242, 2009.
13. Gen Y, Yasui K, Zen Y, Zen K, Dohi O, Endo M, Tsuji K, Wakabayashi N, Itoh Y, Naito Y, Taniwaki M, Nakanuma Y, Okanoue T and Yoshikawa T: SOX2 identified as a target gene for the amplification at 3q26 that is frequently detected in esophageal squamous cell carcinoma. Cancer Genet Cytogenet 202: 82-93, 2010.
14. Wang Q, He W, Lu C, Wang Z, Wang J, Giercksky KE, Nesland JM and Suo Z: OCT3/4 and SOX2 are significantly associated with an unfavorable clinical outcome in human esophageal squamous cell carcinoma. Anticancer Res 29: 1233-1241, 2009.
15. Wilbertz T, Wagner P, Petersen K, Stiedl AC, Scheble VJ, Maier S, Reischl M, Mikut R, Altorki NK, Moch H, Fend F, Staebler A, Bass AJ, Meyerson M, Rubin MA, Soltermann A, Lengerke C and Perner S: SOX2 gene amplification and protein overexpression are associated with better outcome in squamous cell lung cancer. Mod Pathol 24: 944-953, 2011.
16. Tetreault MP, Wang ML, Yang Y, Travis J, Yu QC, Klein-Szanto AJ and Katz JP: KLF4 overexpression activates epithelial cytokines and inflammation-mediated esophageal squamous cell cancer in mice. Gastroenterology 139: 2124-2134.e9, 2010.
17. Zhang G, Zhu H, Wang Y, Yang S, Liu M, Zhang W, Quan L, Bai J, Liu Z and Xu N: Krüppel-like factor 4 represses transcription of the survivin gene in esophageal cancer cell lines. Biol Chem 390: 463-469, 2009.
18. Yang Y, Goldstein BG, Chao HH and Katz JP: KLF4 and KLF5 regulate proliferation, apoptosis and invasion in esophageal cancer cells. Cancer Biol Ther 4: 1216-1221, 2005.