Novel bat influenza virus NS1 proteins bind double-stranded RNA and antagonize host innate immunity

Journal of Virology

Volumn 89, Issue 20, 2015, Pages 10696-10701

  Turkington, Hannah L ^a   Juozapaitis, Mindaugas ^b   Kerry, Philip S ^c,e   Aydillo, Teresa ^d   Ayllon, Juan ^d   García Sastre, Adolfo ^d   Schwemmle, Martin ^b   Hale, Benjamin G ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY OF ST ANDREWS   (United Kingdom)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^e EVOTEC UK LTD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED RNA; NONSTRUCTURAL PROTEIN 1; BETA INTERFERON; INS1 PROTEIN, INFLUENZA VIRUS; ISOPROTEIN; PROTEIN BINDING; RNA BINDING PROTEIN; VIRUS PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; AVIAN INFLUENZA VIRUS; BAT INFLUENZA VIRUS; CHIMERA; HUMAN; INFLUENZA VIRUS; INNATE IMMUNITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANTAGONISM; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN RNA BINDING; RNA BINDING; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; VIRUS REPLICATION; VIRUS VIRULENCE; ANIMAL; BAT; CHEMICAL STRUCTURE; CHEMISTRY; GENE EXPRESSION REGULATION; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; INFLUENZA A VIRUS; METABOLISM; ORTHOMYXOVIRUS INFECTION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; VETERINARY; VIROLOGY;

ANIMALS; CHIROPTERA; GENE EXPRESSION REGULATION; HOST-PATHOGEN INTERACTIONS; IMMUNITY, INNATE; INFLUENZA A VIRUS; INTERFERON-BETA; MODELS, MOLECULAR; ORTHOMYXOVIRIDAE INFECTIONS; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RNA, DOUBLE-STRANDED; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

EID: 84942155957     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01430-15     Document Type: Article

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